Cell transplantation for Parkinson's disease.

Abstract:

:Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of the dopamine producing neurons projecting from the substantia nigra into the corpus striatum. Current medical therapy is limited and cannot stop or reverse the degeneration. Over the past 30 years, attempts were made to change the course of the disease by replacing the lost neurons with grafts from various sources. Recent controlled clinical trials of fetal cell transplantation for PD have had disappointing results. These events present an opportunity to examine the past developments and future direction of cell transplantation for PD.

journal_name

Neurol Res

journal_title

Neurological research

authors

Roitberg B,Urbaniak K,Emborg M

doi

10.1179/016164104225017604

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

355-62

issue

4

eissn

0161-6412

issn

1743-1328

journal_volume

26

pub_type

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