Treadmill exercise is associated with reduction of reactive microgliosis and pro-inflammatory cytokine levels in the hippocampus of type 2 diabetic rats.

abstract：:Compromise of blood flow to the brain leads to cerebral ischemia, which if left untreated may even result in cerebral infarction. This has been the main cause of major morbidity and mortality over the years in the US and around the world. Cerebral ischemia to the posterior fossa is more critical and difficult to treat...

journal_title：Neurological research

authors： Misra M,Alp MS,Hier D,Ausman JI

更新日期：2004-01-01 00:00:00

abstract：:This article covers the basis of tethered cord syndrome as a stretch-induced spinal cord disorder, including pathophysiology, signs and symptoms, imaging diagnosis, indication for surgical treatment, and surgical procedures. Anomalies that cause mechanical spinal cord tethering are listed, and the surgical untethering...

journal_title：Neurological research

authors： Yamada S,Won DJ,Siddiqi J,Yamada SM

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:Daughter aneurysms have been strongly associated with saccular aneurysm rupture. We constructed a mathematical model to help explain this association as a possible hemodynamic mechanism for intracranial saccular aneurysm rupture. METHODS:Our model is based on the assumption that when an aneurysm reaches a s...

journal_title：Neurological research

authors： Meng H,Feng Y,Woodward SH,Bendok BR,Hanel RA,Guterman LR,Hopkins LN

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:The purpose of this study is to use diffusion tensor imaging (DTI) parameters to evaluate cerebral ischemia/reperfusion injury in the infarct core (IC) and ischemic penumbra (IP) in a rhesus transient middle cerebral artery occlusion (MCAO) model. METHODS:Seven rhesus monkeys were used to construct the MCAO...

journal_title：Neurological research

authors： Guo J,Zheng HB,Duan JC,He L,Chen N,Gong QY,Tang HH,Li HX,Wang L,Cheng JQ

更新日期：2011-01-01 00:00:00

abstract：:This paper presents the results of transsphenoidal surgery in 41 consecutive patients with visual loss from pituitary adenomas. The most common pattern of loss was bitemporal hemianopia. Transsphenoidal decompression resulted in visual improvement in 78% of patients. If patients with optic atrophy and pre-operative co...

journal_title：Neurological research

authors： el-Azouzi M,Black PM,Candia G,Zervas NT,Panagopoulos KP

更新日期：1990-03-01 00:00:00

abstract：:Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...

journal_title：Neurological research

authors： Droste DW,Sonne M,Siemens HJ,Kaps M

更新日期：1996-10-01 00:00:00

abstract：:Ninety percent of cerebral aneurysms were diagnosed after their first rupture with consecutive subarachnoid haemorrhage. In order to detect the aneurysms before rupture investigation by transcranial Doppler sonography was used on the basis of intra-operative evaluation of the normal aneurysmal flow pattern. In 34 pati...

journal_title：Neurological research

authors： Gilsbach JM,Harders AG

更新日期：1989-03-01 00:00:00

abstract：:Huntington's disease is an inherited neurodegenerative disorder, characterized by loss of spiny neurons in the striatum and cortex, which usually happens in the third or fourth decades of life. In advanced form of the disease, progressive striatum atrophy happens and medium spiny neurons, which occupy more than 80% of...

journal_title：Neurological research

authors： Amin EM,Reza BA,Morteza BR,Maryam MM,Ali M,Zeinab N

更新日期：2008-12-01 00:00:00

abstract：:The therapeutic effect of insulin alone or insulin combined with 30 min delayed thrombolytic therapy was investigated in rats embolized in the right hemisphere with a fibrin clot made from autologous blood. Animals were killed seven days after embolization and the infarct volumes were measured in % of the affected hem...

journal_title：Neurological research

authors： Meden P,Andersen M,Overgaard K,Rasmussen RS,Boysen G

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the characteristics of atherosclerotic middle cerebral artery (MCA) stenosis by high-resolution magnetic resonance imaging (HR-MRI) and determine the relationship between wall characteristics and infarction patterns. METHODS:Thirty-six patients with acute ischaemic stroke due to MCA stenosis unde...

journal_title：Neurological research

authors： Zhao DL,Deng G,Xie B,Gao B,Peng CY,Nie F,Yang M,Ju S,Teng GJ

更新日期：2016-07-01 00:00:00

abstract：:We examined the effect of local anaesthesia of the skin on somatosensory evoked potentials (SEPs) and psychophysical magnitude estimates for a constant intensity air-puff stimulation (7 kg.cm-2) in 23 normal subjects. Before and after intradermal injection (0.1 ml of 1% xylocain) to the tip of the right index finger, ...

journal_title：Neurological research

authors： Hashimoto I,Yoshikawa K,Gatayama T,Sasaki M,Nomura M,Yokoyama S,Sano K

更新日期：1995-02-01 00:00:00

abstract：:This paper reviews our recent studies of the role of cortical spreading depression (CSD) in the pathogenesis of brain disorders. Our investigation is a computational one, involving the development and utilization of a complex neuro-metabolic model of the interactions assumed to occur in the cortex during the passage o...

journal_title：Neurological research

authors： Ruppin E,Reggia JA

更新日期：2001-07-01 00:00:00

abstract：:Background Transtemporal Doppler (TTD) with middle cerebral artery (MCA) is widely used for right-to-left shunt (RLS) detection. However, an alternative method for patients without suitable temporal bone windows should be established. The present study prospectively evaluated the effectiveness of transorbital Doppler ...

journal_title：Neurological research

authors： Duan Z,Yang Z,Song B,Ma C,Li Y,Du Y,Shang D,Li S,Lou J

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:We attempted to determine whether a functional polymorphism of TRPM6 (rs2274924) is associated with susceptibility to epilepsy following ischemic stroke, and to further explore the effect of this polymorphism on serum levels of Mg2+ in post-stroke patients. METHODS:We carried out a case-control study on 378...

journal_title：Neurological research

authors： Fu CY,Chen SJ,Cai NH,Liu ZH,Zhang M,Wang PC,Zhao JN

更新日期：2019-04-01 00:00:00

abstract：:Traumatic brain injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. Specific topics addressed in this paper include magnitude of the problem, causes, context of injury occurrence, risk factors, severity, outcome and impact of TBIs on...

journal_title：Neurological research

authors： Gururaj G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:The aim of this report was to set up an effective experimental model of cocultures between cells from spinal cord explants and myotubes from adductor muscle. METHODS:We obtained neuronal cells from chick spinal cord explants at embryonic day 5 (ED5) by means of an enzymatic digestion. Small spinal cord fragm...

journal_title：Neurological research

authors： Martinello T,Patruno M

更新日期：2008-03-01 00:00:00

abstract：:Induction of stress proteins is thought to be important in the protection of cells from a variety of environmental insults including heat, hypoxia and ischemia. The aim of this study was to compare the mechanism of induction of heat shock protein 72 (HSP72) in primary cultures of murine cortical astrocytes by heat and...

journal_title：Neurological research

authors： Bergeron M,Mivechi NF,Giaccia AJ,Giffard RG

更新日期：1996-02-01 00:00:00

abstract：:Tissue PCO2 (carbon dioxide tension) (PtCO2), interstitial H+ (H+e) and potassium activities (K+e) were monitored in the cerebral cortex of rats during and after 2-3 min of anoxia. Anoxia was associated with systemic hypotension and caused H+e (extracellular hydrogen ion activity) to increase from pH approximately equ...

journal_title：Neurological research

authors： Ohno M,Obrenovitch TP,Hartell N,Barratt S,Bachelard HS,Symon L

更新日期：1989-09-01 00:00:00

abstract：:The effect of labetalol, a combined alpha- and beta-adrenoceptor antagonist, on the cerebral circulation was investigated in 7 normotensive subjects. Cerebral blood flow (CBF) was measured with the intravenous 133Xe method and mean flow velocity (Vmean) in the middle cerebral artery was determined using transcranial D...

journal_title：Neurological research

authors： Schroeder T,Schierbeck J,Howardy P,Knudsen L,Skafte-Holm P,Gefke K

更新日期：1991-03-01 00:00:00

abstract：:Magnetic resonance (MR) is a powerful new imaging modality which has recently become competitive with X-ray computed tomography (CT) for imaging of the central nervous system (CNS). The advantages of MR include lack of ionizing radiation and the necessity to use iodinated contrast. MR is able to image directly in the ...

journal_title：Neurological research

authors： Bradley WG Jr

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to analyse inflammatory cells in lumbar disc tissue under cyclooxygenase-2 (COX-2) inhibitor therapy, to detect their prevalence in different subtypes of lumbar disc herniations and to assess the influence of inflammatory reactions in herniated disc tissue on postoperative out...

journal_title：Neurological research

authors： Aydin MV,Sen O,Kayaselcuk F,Bolat F,Tufan K,Caner H,Altinors N

更新日期：2005-09-01 00:00:00

abstract：:Mild vascular cognitive impairment (mVCI) is a broader term that is intended to detect cognitive loss before the development of dementia. The identification of preventable risk factors as well as therapeutic strategies of intervention is still unclear. It has been suggested that carotid endarterectomy (CEA) improves c...

journal_title：Neurological research

authors： Borroni B,Tiberio G,Bonardelli S,Cottini E,Facheris M,Akkawi N,Pezzini A,Cervi E,Giulini SM,Padovani A

更新日期：2004-07-01 00:00:00

abstract：:The abnormal muscle response, elicited by electrical stimulation of one branch of the facial nerve and recorded from muscles innervated by another branch, has been used previously as an objective sign of hemifacial spasm in the development of animal models of this disorder. In the present study we recorded spontaneous...

journal_title：Neurological research

authors： Kuroki A,Møller AR

更新日期：1994-08-01 00:00:00

abstract：:A new and reproducible saccular aneurysm model has been developed at the bifurcation of the common carotid artery in rats. The details of the experimental methods and results are described. It is strongly suggested that the internal elastic lamina is a critical layer in saccular aneurysm formation, because an experime...

journal_title：Neurological research

authors： van Alphen HA,Gao YZ,Kamphorst W

更新日期：1990-12-01 00:00:00

abstract：:The normal cerebral circulation has the ability to maintain a stable cerebral blood flow over a wide range of cerebral perfusion pressures and this is known as cerebral autoregulation. This autoregulation may be impaired in the injured brain. Closed head injury was induced in 28 Sprague-Dawley rats weighing 400-450 g....

journal_title：Neurological research

authors： Prat R,Markiv V,Dujovny M,Misra M

更新日期：1997-08-01 00:00:00

abstract：:Cerebral hemorrhages are subject to a heavy short- and long-term case fatality. A study of prognostic factors and of relative survival based on the data of a population registry is of great value to study patients having a hematoma of all ages, irrespective of the method of care. We have listed 183 patients having a c...

journal_title：Neurological research

authors： el Chami B,Milan C,Giroud M,Sautreaux JL,Faivre J

更新日期：2000-12-01 00:00:00

abstract：:Objectives: Neurovascular compression syndromes (NVCS) could be cured with an intravascular device that releases compression of the root entry zone of cranial nerves by changing the course of offending vessels. The purpose of this study was to report our results of in vitro and in vivo experiments with a novel intra-a...

journal_title：Neurological research

authors： Chun Y,Chen Y,Elsisy M,Sukinik J,Shridhar P,Park JK,Kim YB,Hong CK,Chung J

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Music-supported therapy (MST) is a new approach for motor rehabilitation of stroke patients. Recently, many studies have demonstrated that MST improved the motor functions of post-stroke patients. However, the underlying mechanism for this effect is still unclear. It may result from repeated practice or repea...

journal_title：Neurological research

authors： Tong Y,Forreider B,Sun X,Geng X,Zhang W,Du H,Zhang T,Ding Y

更新日期：2015-05-01 00:00:00

abstract：:Excessive entry of Ca2+ into injured cochlear neurons activates various Ca(2+)-activated enzymes and subsequent spiral ganglion cell death. Therefore, preventing intracellular calcium overload by using Ca2+ channel antagonists may become an important countermeasure to spiral ganglion cell death. We experimentally inve...

journal_title：Neurological research

authors： Sekiya T,Yagihashi A,Asano K,Suzuki S

更新日期：2002-12-01 00:00:00