Abstract:
:This paper presents the results of transsphenoidal surgery in 41 consecutive patients with visual loss from pituitary adenomas. The most common pattern of loss was bitemporal hemianopia. Transsphenoidal decompression resulted in visual improvement in 78% of patients. If patients with optic atrophy and pre-operative complete blindness were excluded, improvement extended to 94% of patients. Because of its efficacy and low morbidity, transsphenoidal resection of pituitary tumours is the procedure of choice for most adenomas with extrasellar extension and visual field loss.
journal_name
Neurol Resjournal_title
Neurological researchauthors
el-Azouzi M,Black PM,Candia G,Zervas NT,Panagopoulos KPdoi
10.1080/01616412.1990.11739907subject
Has Abstractpub_date
1990-03-01 00:00:00pages
23-5issue
1eissn
0161-6412issn
1743-1328journal_volume
12pub_type
杂志文章abstract::The relationship between the states of spinal impact injuries and magnetically evoked electromyograms (EMGs) were studied in rats. Impact injuries to the spinal cord were induced at a depth of 0.25-2.0 mm by insertion of a cylinder tip measuring 2 mm in diameter into the lumbar vertebrae L1-L2. Magnetically induced el...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2000.11740747
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVES:Changes in systemic arterial blood pressure and the degree of cerebral vasospasm were investigated in 125 patients with aneurysmal subarachnoid hemorrhage. METHODS:Systemic arterial blood pressure was measured every 2 hours in each patient for a period of more than 2 weeks, and a fall in systemic blood pres...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X48761
更新日期:2006-03-01 00:00:00
abstract::Endolymphatic sac tumors are rare, low-grade adenocarcinomas of the petrous bone. These tumors are highly vascularized and surgical removal is often challenging. We present a staged endovascular-neurosurgical approach consisting of stent-assisted angioplasty of the petrous carotid, selective endovascular embolization ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164103101201436
更新日期:2003-04-01 00:00:00
abstract::The effects of etomidate on focal cerebral ischaemia following transorbital occlusion of the cat middle cerebral artery were investigated. Etomidate had no effect on CBF before or after onset of ischaemia by comparison with controls, but caused a greater fall in CBF in cats with high preocclusion or initial ischaemic ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1986.11739756
更新日期:1986-12-01 00:00:00
abstract:OBJECTIVE:This study assesses the clinical outcome after early combined cranioplasty (own frozen bone) and shunt implantation (Codman-Medos programmable VP shunt) in patients with skull bone defects and cerebrospinal fluid (CSF) circulation disorders. METHOD:Medical records were reviewed retrospectively for the last 1...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164106X98008
更新日期:2006-03-01 00:00:00
abstract:INTRODUCTION:Alzheimer's disease (AD) is the most common neurodegenerative disease across the world. The major cause of AD is extensive oxidative stress and inflammation in central nervous system (CNS). Vitamin D3 and E are the most known vitamins that control oxidative stress and mitochondrial respiratory function. Th...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1787624
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system. A contribution from complement has long been suspected. We investigated the association of complement factor H (CFH) Tyr402 His gene polymorphism and serum level in Egyptian patients with MS to examine whet...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132815Y.0000000075
更新日期:2015-10-01 00:00:00
abstract::Objectives: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). Methods: Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.5 h, 6...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2019.1672388
更新日期:2019-11-01 00:00:00
abstract::Alzheimer disease (AD), a central nervous system degenerative disease, is characterized by abnormal deposition of amyloid-β peptide (Aβ), neurofibrillary tangles formed by hyperphosphorylated tau and synaptic loss. It is widely accepted that Aβ is the chief culprit of AD. Aβ peptide is the cleavage product of amyloid-...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1080/01616412.2015.1133485
更新日期:2016-02-01 00:00:00
abstract::A series of 15 arteriovenous malformations (AVMs) of the corpus callosum--9% of 170 intracranial AVMs admitted to the School of Medicine of the University of Rome during a 30-yr period--was studied. In all cases the lesion concerned mainly the corpus callosum, although in some it also involved the surrounding structur...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1982.11739626
更新日期:1982-01-01 00:00:00
abstract::This paper describes a test prototype for precision robot-assisted surgery using a hexapod operating robot and a movable operating cockpit for tactile feedback. The objective of the work described is twofold: 1, to evaluate the use of hexapod robots for precisely manipulating endoscopes and surgical instruments in sub...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1999.11740887
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:Intravenous administration of recombinant tissue plasminogen activator (rtPA) is known as the only approved treatment for acute ischemic stroke. However, it is still controversial whether acute ischemic stroke patients with atrial fibrillation should receive rtPA therapy. METHODS:We studied 99 patients altog...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12656393665206
更新日期:2010-05-01 00:00:00
abstract::Ninety percent of cerebral aneurysms were diagnosed after their first rupture with consecutive subarachnoid haemorrhage. In order to detect the aneurysms before rupture investigation by transcranial Doppler sonography was used on the basis of intra-operative evaluation of the normal aneurysmal flow pattern. In 34 pati...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1989.11739860
更新日期:1989-03-01 00:00:00
abstract:OBJECTIVES:Papaverine has been used in treating vasospasm following subarachnoid hemorrhage (SAH). However, its action mechanism for cerebral vascular relaxation is not clear. Potassium and calcium channels are closely related to the contraction and relaxation of cerebral smooth muscle. Therefore, to identify the role ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X191021
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X385617
更新日期:2009-11-01 00:00:00
abstract::Phosphorus magnetic resonance spectroscopy (31P-MRS) was made to measure changes in brain high energy phosphate compounds, adenosine triphosphate (ATP) and phosphocreatine (PCr), inorganic phosphorus (Pi) and intracellular pH (pHi) during a prolonged period of incomplete brain ischaemia produced, in anaesthetized dogs...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1990.11739943
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVES:Patients presenting to the emergency room with an acute or subacute onset of focal neurological deficits are evaluated initially by non-contrast computed tomogram (CT) of the brain. This is primarily carried out to differentiate an ischemic from hemorrhagic stroke. However, other neurological conditions may ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164109X12445505689607
更新日期:2009-10-01 00:00:00
abstract::We assessed the effect of a novel calmodulin antagonist, DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) in a spontaneously hypertensive rat (SHR) permanent focal cerebral ischemia. In experiment I, the left middle cerebral ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198992
更新日期:2001-09-01 00:00:00
abstract::No marker that predicts accurately the time of occurrence of cerebral vasospasm due to subarachnoid hemorrhage (SAH) has been reported. In the present study, membrane-bound tissue factor (mTF) and myelin basic protein (MBP) concentrations in cerebrospinal fluid (CSF) were evaluated as a predictor of the time of occurr...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199225
更新日期:2001-10-01 00:00:00
abstract::This study comprises scientific-theoretic fundamental investigations of laserneedle technology, a new and painless method of acupuncture stimulation. Laserneedles are not inserted in the skin, but are merely placed on the surface of the acupuncture point. The study documents the significant changes in peripheral micro...
journal_title:Neurological research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1179/016164103101202237
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To study histopathologic changes and the role of the microglia/macrophage cell in the therapeutic effect of I-125 interstitial brachytherapy on the cerebral gliomas. METHODS:Out of a series of 60 cases with cerebral astrocytomas and other brain tumors treated with I-125 interstitial brachytherapy, autopsy ma...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1179/016164107X158875
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVES:To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS. METHODS:Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1792700
更新日期:2020-11-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, whose relentless course leads to death within 2-5 years, generally due to respiratory failure. Apart from the age and site of onset, no other factors have consistently demonstrated to be related to the ALS outc...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000049
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVES:Although magnesium is a well-known treatment for vasospasm following subarachnoid hemorrhage, its mechanism of action for cerebral vascular relaxation is not clear. In addition, it is known that L-type calcium (Ca(2+)) channels play a pivotal role in smooth muscle contraction. To investigate the role of L-t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000016
更新日期:2012-04-01 00:00:00
abstract::Insertion of pedicle screws in the thoracolumbar spine can be challenging. Incorrect placement can lead to a failure of fusion or to significant neurologic morbidity. Recently, techniques utilizing intraoperative monitoring and stereotaxis have been developed to achieve proper screw placement. While these techniques m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740877
更新日期:1997-12-01 00:00:00
abstract::Our goal was to clarify the optimum management of the inaccessible unruptured giant and large aneurysms of the internal carotid artery (ICA). Since 1981, we have treated 18 patients with unclippable unruptured giant or large aneurysms of the ICA. Aneurysms were classified as either intracavernous or intradural. We per...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198604
更新日期:2001-06-01 00:00:00
abstract::Mild vascular cognitive impairment (mVCI) is a broader term that is intended to detect cognitive loss before the development of dementia. The identification of preventable risk factors as well as therapeutic strategies of intervention is still unclear. It has been suggested that carotid endarterectomy (CEA) improves c...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164104225016245
更新日期:2004-07-01 00:00:00
abstract::Neural stem cells (NSCs) are self-renewable, multipotential cells capable of differentiating into the three major neural cell types, but the mechanisms which regulate their development are not fully understood. Both basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) promote the proliferation of NS...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199090
更新日期:2001-09-01 00:00:00
abstract::Basic fibroblast growth factor (bFGF) possesses neuroprotective effects on a variety of neurons. Here we report that it delays progression of motor neuron disease (MND) in the wobbler mouse. After initial diagnosis of MND at post-natal age 3-4 weeks, wobbler mice receive either recombinant human bFGF (1 mg kg-1, n = 1...
journal_title:Neurological research
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164110X12644252260592
更新日期:2010-04-01 00:00:00