Mechanism of heat shock protein 72 induction in primary cultured astrocytes after oxygen-glucose deprivation.

abstract：:The association between glucocerebrosidase (GBA) mutations and Parkinson's disease (PD) is attracting increased attention worldwide. Results from previous studies on the association of GBA mutations with PD in different ethnicities remain contradictory. In order to derive a more comprehensive understanding of the rela...

journal_title：Neurological research

authors： Mao X,Wang T,Peng R,Chang X,Li N,Gu Y,Zhao D,Liao Q,Liu M

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Elevated homocysteine level is a risk factor for ischemic stroke and associated with small vessel disease such as confluent leukoaraiosis in white and black population. We investigated the relationship between the total serum homocysteine level and ischemic stroke subtypes in Chinese population. METHODS:Thre...

journal_title：Neurological research

authors： Ma Y,Zhao X,Zhang W,Liu L,Wang Y,Fang R,Wang Y

更新日期：2010-07-01 00:00:00

abstract：:Insertion of pedicle screws in the thoracolumbar spine can be challenging. Incorrect placement can lead to a failure of fusion or to significant neurologic morbidity. Recently, techniques utilizing intraoperative monitoring and stereotaxis have been developed to achieve proper screw placement. While these techniques m...

journal_title：Neurological research

authors： Frank EH,Chamberland DL

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Tadalafil is a selective phosphodiesterase type 5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction. Less is known about the electroencephalography (EEG) effects of PDE-5 inhibitors, and the present study, therefore, examined the risk of EEG abnormalities associated with tadalafil. METHOD:...

journal_title：Neurological research

authors： Okuyucu EE,Guven O,Duman T,Gorur S,Melek IM,Akcin S,Yilmazer S

更新日期：2009-04-01 00:00:00

abstract：:Promyelocytic leukemia (PML) protein is involved in apoptotic death of cultured neuronal cells, but its role in ischemic brain damage remains uncertain. In this study, we investigated change of immunoreactivity for PML protein in rat brain after transient middle cerebral artery occlusion, and compared the results with...

journal_title：Neurological research

authors： Hayashi T,Sasaki C,Iwai M,Sato K,Zhang WR,Warita H,Abe K

更新日期：2001-10-01 00:00:00

abstract：:There have been reports that superior cervical ganglionectomy (SCG) is effective as a treatment for cerebral vasospasm following subarachnoid haemorrhage (SAH). On the other hand, denervation supersensitivity is supposed to play an important role in vasospasm. The two accounts contradict each other. To investigate thi...

journal_title：Neurological research

authors： Iwai R,Kamiyama K,Nagahori T,Ohtsuji T,Endo S,Takaku A

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:To evaluate by MR diffusion weighted image (DWI-MR) the presence of new ischemic cerebral lesions after carotid artery stenting (CAS) and distal cerebral protection, in patients with internal carotid artery (ICA) stenosis >70. METHODS:Sixty-seven CAS were performed under cerebral protection with a distal fil...

journal_title：Neurological research

authors： González A,Piñero P,Martínez E,González-Marcos JR,Rafel E,Mayol A,Gil-Peralta A

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:The actual relationship between neural stem cells and SDF-1alpha/CXCR4 after brain injury has not yet been elucidated, although recent studies have speculated that stromal cell-derived factor-1alpha (SDF-1alpha) and its receptor, CXCR4, could contribute to neural stem cells migration after brain injury. In th...

journal_title：Neurological research

authors： Itoh T,Satou T,Ishida H,Nishida S,Tsubaki M,Hashimoto S,Ito H

更新日期：2009-02-01 00:00:00

abstract：:The efficacy of delayed thrombolysis with recombinant tissue plasminogen activator was tested in combination with the ischaemic protecting drug NBQX in an embolic stroke model. In 113 rats the carotid territory was embolized with a fibrin-rich clot formed in polyethylene tube. Hemispheric cerebral blood flow (CBF) was...

journal_title：Neurological research

authors： Overgaard K,Sereghy T,Pedersen H,Boysen G

更新日期：1993-10-01 00:00:00

abstract：:Alzheimer disease (AD), a central nervous system degenerative disease, is characterized by abnormal deposition of amyloid-β peptide (Aβ), neurofibrillary tangles formed by hyperphosphorylated tau and synaptic loss. It is widely accepted that Aβ is the chief culprit of AD. Aβ peptide is the cleavage product of amyloid-...

journal_title：Neurological research

authors： Zheng BW,Yang L,Dai XL,Jiang ZF,Huang HC

更新日期：2016-02-01 00:00:00

abstract：:This study was designed to assess the effects of volume expansion with Fluosol-DA and hetastarch on local cerebral blood flow (CBF), cortical O2 availability (O2a) and computerized EEG power data during cerebral ischaemia in a primate stroke model. Focal cerebral ischaemia was produced in 20 anaesthetized Macaca monke...

journal_title：Neurological research

authors： Tranmer BI,Iacobacci R,Feiler S

更新日期：1990-03-01 00:00:00

abstract：:We describe the advantages and clarify the technical key points of a microendoscopic, minimally invasive technique to the posterior surgical approach for cervical degenerative disease. The authors studied the microendoscopic posterior approach using the METRx system in both cadaver models and in clinical cases. This n...

journal_title：Neurological research

authors： Yuguchi T,Nishio M,Akiyama C,Ito M,Yoshimine T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Ischemic stroke is one of the most common causes of death worldwide. Early and accurate prediction of outcome in acute ischemic stroke (AIS) is important and influences risk-optimized therapeutic strategies. We investigated the changes in high-sensitivity C-reactive protein (Hs-CRP) and homocysteine (HCY) le...

journal_title：Neurological research

authors： Tu WJ,Zhao SJ,Liu TG,Yang DG,Chen H

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:Cocaine- and amphetamine-regulated transcript (CART) peptide has been demonstrated to exert neuroprotective effects in stroke and some neurodegeneration diseases. In current study, we investigated the protective effects and underlying mechanisms of CART in APP/PS1 mice. METHODS:The protein levels of CART,...

journal_title：Neurological research

authors： Yin K,Jin J,Zhu X,Yu L,Wang S,Qian L,Han L,Xu Y

更新日期：2017-10-01 00:00:00

abstract：:Previous work has shown that unsaturated fatty acid components of model membrane phospholipids in vitro, damaged via a free radical mechanism, are protected by the presence of cholesterol in these membranes. The participation of these membrane lipids in the pathogenesis of traumatic injury to brain was studied in vivo...

journal_title：Neurological research

authors： Mitamura JA,Seligman ML,Solomon JJ,Flamm ES,Demopoulos HB,Ransohoff J

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:We evaluate the bladder volume and pressure through recording the bladder afferent activity in the sacral nerve roots in acute experiments of paraplegic dogs. These measurements are intended to report the status of the bladder and to adjust the stimulation parameters of an implantable electric stimulator. ME...

journal_title：Neurological research

authors： Saleh A,Sawan M,Elzayat EA,Corcos J,Elhilali MM

更新日期：2008-02-01 00:00:00

abstract：:Using magnetic resonance imaging, we reviewed 141 infratentorial infarcts in 81 consecutive cases: 65 infarcts were seen in the paramedian pons, while 18 in the posterior inferior cerebellar artery (PICA) territory and 17 in the watershed area between PICA and superior cerebellar artery. No comparable sign or symptom ...

journal_title：Neurological research

authors： Yin WM,Nagata K,Satoh Y,Yokoyama E,Watahiki Y,Yuya H,Hirata Y,Ogawa T,Inugami A

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:Spinal cord injury (SCI) causes muscle atrophy, which is particularly severe, due to inability to perform tetanic contractions, when lower motor neurons (LMN) are involved. We performed a longitudinal study in 25 Europeans suffering from complete conus cauda syndrome from 0.7 to 8.7 years comparing functional...

journal_title：Neurological research

authors： Kern H,Carraro U,Adami N,Hofer C,Loefler S,Vogelauer M,Mayr W,Rupp R,Zampieri S

更新日期：2010-02-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) possesses neuroprotective effects on a variety of neurons. Here we report that it delays progression of motor neuron disease (MND) in the wobbler mouse. After initial diagnosis of MND at post-natal age 3-4 weeks, wobbler mice receive either recombinant human bFGF (1 mg kg-1, n = 1...

journal_title：Neurological research

authors： Ikeda K,Iwasaki Y,Tagaya N,Shiojima T,Kobayashi T,Kinoshita M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Intracranial artery stenosis may be the most frequent cause of ischemic stroke in the world. Early detection of asymptomatic intracranial artery stenosis may allow for therapeutic intervention. Most elements of the Framingham stroke risk profile (FSRP) are also risk factors for intracranial artery stenosis....

journal_title：Neurological research

authors： Zhang Y,Wu S,Jia Z,Zhou Y,Liu X,Wang W,Wang T,Wang L,Zhang S,Jin C,Zhao X

更新日期：2012-05-01 00:00:00

abstract：:Choroid plexus carcinoma in an adult case is a very rare tumor and difficult to differentiate from metastatic tumors. The authors report a case of a 49-year-old female with choroid plexus carcinoma who previously had multiple carcinomas. In this case, synaptophysin immunohistochemistry proved to be extremely helpful f...

journal_title：Neurological research

authors： Kohmura E,Maruno M,Sawada K,Arita N,Yoshimine T

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:The present study investigated the effects of tetrahydrobiopterin (BH4) on cerebral infarction after transient focal ischemia in rats. METHODS:Focal ischemia (1·5 hours) was created in male Sprague-Dawley rats (250-280 g) by middle cerebral artery occlusion. Some rats were treated with 20 mg/kg tetrahydrob...

journal_title：Neurological research

authors： Tang LL,Zheng JS

更新日期：2011-12-01 00:00:00

abstract：:An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...

journal_title：Neurological research

authors： Sano K

更新日期：1980-01-01 00:00:00

abstract：:Refractory status epilepticus (RSE), defined as status epilepticus that fails to respond to the acute administration of two antiepileptic medications, occurs in approximately a third of patients with status epilepticus, and is associated with increased hospital length of stay, mortality, and functional disability. Com...

journal_title：Neurological research

authors： Hocker S,Wijdicks EF,Rabinstein AA

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:To review the historical development and current status of endovascular techniques used in the treatment of symptomatic vasospasm following aneurysmal subarachnoid hemorrhage. METHODS:This article summarizes the relevant literature on neurointerventional therapy for vasospasm, namely instillation of intraar...

journal_title：Neurological research

authors： Brisman JL,Eskridge JM,Newell DW

更新日期：2006-10-01 00:00:00

abstract：:Objectives: Increased attention is being paid to Asian medicine in balanced total health care. We investigated the effects of mixed exercise including yoga ('Yoga-plus') among elderly individuals. Methods: A total of 385 subjects (72 males and 313 females, 75.5 ± 8.7 years old) participated in a 12-month (M) exercise ...

journal_title：Neurological research

authors： Hishikawa N,Takahashi Y,Fukui Y,Tokuchi R,Furusawa J,Takemoto M,Sato K,Yamashita T,Ohta Y,Abe K

更新日期：2019-11-01 00:00:00

abstract：:Excessive entry of Ca2+ into injured cochlear neurons activates various Ca(2+)-activated enzymes and subsequent spiral ganglion cell death. Therefore, preventing intracellular calcium overload by using Ca2+ channel antagonists may become an important countermeasure to spiral ganglion cell death. We experimentally inve...

journal_title：Neurological research

authors： Sekiya T,Yagihashi A,Asano K,Suzuki S

更新日期：2002-12-01 00:00:00

abstract：:Experiments were carried out to clarify the effect of serotonin [5-hydroxytryptamine (5-HT)] upon the somatosensory evoked potential (SEP) elicited by superficial radial nerve stimulation in cat, and the following results were obtained: (i) in untreated (control) animals, a significant reduction occurred in amplitude ...

journal_title：Neurological research

authors： Iwayama K,Mori K,Fukushima M,Yamashiro K

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to characterize mouse neural stem cells (NSC) transduced by a multigenic lentiviral vector (LV) and stably express recombinant human nerve growth factor (rhNGF). We obtained NSC-derived cell lines which express human NGF in relevant amount to exploit their ability for therapeuti...

journal_title：Neurological research

authors： Cenciarelli C,Budoni M,Mercanti D,Fernandez E,Pallini R,Aloe L,Cimino V,Maira G,Casalbore P

更新日期：2006-07-01 00:00:00

abstract：:The elements of peripheral nerve regeneration comprise a complex combination of nerve growth, muscle satellite cells proliferation and differentiation and vessel growth. There is also increasing evidence that growth factors may act at multiple levels in the regenerative response. One such factor affecting multiple cel...

journal_title：Neurological research

authors： Rabinovsky ED

更新日期：2004-03-01 00:00:00