Abstract:
:Insertion of pedicle screws in the thoracolumbar spine can be challenging. Incorrect placement can lead to a failure of fusion or to significant neurologic morbidity. Recently, techniques utilizing intraoperative monitoring and stereotaxis have been developed to achieve proper screw placement. While these techniques may be accurate, they are expensive and may require additional operating room personnel. We have developed an endoscopic pedicle probe for placement of pedicle screws that may overcome some of these limitations. A small 1.2 mm endoscope was adapted to fit within a hollow pedicle probe. Irrigation was provided via a separate channel within the endoscope. Images from the probe were displayed both on a monitor screen and on a heads up display. The endoscopic probe was used to probe 36 sawbone and 22 cadaver thoracolumbar pedicles. After cannulation each specimen was examined to assess nonvisualized pedicle perforation. In sawbones, perforation was visualized endoscopically in 3 pedicles (8%) with no further perforations found on later direct examination. In cadavers the cortical cancellous interface was adequately visualized and no perforations occurred. These preliminary results suggest that the endoscopic probe may have utility in the placement of thoracolumbar pedicle screws.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Frank EH,Chamberland DLdoi
10.1080/01616412.1997.11740877subject
Has Abstractpub_date
1997-12-01 00:00:00pages
657-61issue
6eissn
0161-6412issn
1743-1328journal_volume
19pub_type
杂志文章abstract::We describe a novel approach for analysing the hemodynamic alterations that result after focal cerebral ischemia. This approach utilizes a temporal correlation analysis of first pass transit data obtained with functional imaging. First pass transits of injected contrast agents are measured with dynamic CT scanning. No...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1996.11740394
更新日期:1996-04-01 00:00:00
abstract::Recent work has suggested that one factor in the etiology of the neuromuscular disease, amyotrophic lateral sclerosis (ALS), may be an autoimmune mechanism in which presynaptic voltage-sensitive calcium channels are an antigenic target. We have developed a fluorescence technique to measure rapid Ca2+ influx through pr...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740785
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:This study assesses the clinical outcome after early combined cranioplasty (own frozen bone) and shunt implantation (Codman-Medos programmable VP shunt) in patients with skull bone defects and cerebrospinal fluid (CSF) circulation disorders. METHOD:Medical records were reviewed retrospectively for the last 1...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164106X98008
更新日期:2006-03-01 00:00:00
abstract::Precocious puberty and amenorrhea have been associated with hydrocephalus, but the pathogenesis has not been determined. Approximately 22 cases of amenorrhea, and a few cases of precocious puberty, have been reported in hydrocephalic patients. Shunt treatment leads to initiation and maintenance of normal reproductive ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1080/01616412.2000.11741047
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1787661
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The predictive effect of blood cell ratio on ischemic event has been widely confirmed. Whether PWR and PNR can assess the risk of endovascular treatment (EVT) is largely unclear. This study aimed to investigate the prognostic value of PNR and PWR in acute ischemic stroke patients treated with EVT...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1790868
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:Meningiomas are benign intracranial tumors growing from the arachnoid cap cells. Although their behavior is usually benign, they tend to recur even after total removal, and their recurrence is dependent on different aspects. METHODS:Between 1991 and 2002, 463 patients with an intracranial meningioma were ope...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313208X338043
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:Membrane disruption is one of the main factors that cause axonal damage and functional deficits manifested in spinal cord injury (SCI). In this study, we used polyethylene glycol (PEG) to induce immediate membrane sealing and to promote functional recovery after SCI. METHODS:The effects of PEG (200-2000 Da)...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000133
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Ischemic stroke is one of the most common causes of death worldwide. Early and accurate prediction of outcome in acute ischemic stroke (AIS) is important and influences risk-optimized therapeutic strategies. We investigated the changes in high-sensitivity C-reactive protein (Hs-CRP) and homocysteine (HCY) le...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000228
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:Tadalafil is a selective phosphodiesterase type 5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction. Less is known about the electroencephalography (EEG) effects of PDE-5 inhibitors, and the present study, therefore, examined the risk of EEG abnormalities associated with tadalafil. METHOD:...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X382548
更新日期:2009-04-01 00:00:00
abstract::Microsurgical anatomy for the pterional approach was studied regarding the origin and the course of the ophthalmic artery and the distal dural ring using human cadaveric specimens, with special reference to the surrounding bony structures. In 50 human adult formalin-fixed cadaveric cerebral hemispheres and 10 block sp...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198703
更新日期:2001-06-01 00:00:00
abstract::Parkinson's disease (PD) the second most common age-associated progressive neurodegenerative disorder is characterized by loss of dopaminergic neurons, cytoplasmic inclusions of aggregated proteins (Lewy bodies), and neuroinflammation. The inflammation of neurons causes release of various inflammatory mediators (IFNs,...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1249997
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313208X325191
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:One of the important causes of failed back surgery is the extensive peridural fibrosis collecting in the surgical field after spinal surgeries. Today we know that inflammatory mechanisms mediated by the immune system of the body plays an important role in generation of fibrosis. Azithromycin, a macrolide anti...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12767786356471
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:One of the main obstacles of electrode implantation in epilepsy surgery is the electrode shift between implantation and the day of explantation. We evaluated this possible electrode displacement using intraoperative MRI (iopMRI) data and CT/MRI reconstruction. METHODS:Thirteen patients (nine female, four ma...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1484588
更新日期:2018-10-01 00:00:00
abstract::The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740795
更新日期:1997-04-01 00:00:00
abstract::The efficacy of delayed thrombolysis with recombinant tissue plasminogen activator was tested in combination with the ischaemic protecting drug NBQX in an embolic stroke model. In 113 rats the carotid territory was embolized with a fibrin-rich clot formed in polyethylene tube. Hemispheric cerebral blood flow (CBF) was...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1993.11740159
更新日期:1993-10-01 00:00:00
abstract::Although radiation injuries to the brain are well documented, immediate early histological changes in the brain remain to be defined. The present study characterizes glial injury provoked in adult rat white matter within 24 h after a single irradiation of the whole brain (10 or 20 Gray). Irradiated brains were histolo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199324
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:We evaluate the bladder volume and pressure through recording the bladder afferent activity in the sacral nerve roots in acute experiments of paraplegic dogs. These measurements are intended to report the status of the bladder and to adjust the stimulation parameters of an implantable electric stimulator. ME...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164108X268250
更新日期:2008-02-01 00:00:00
abstract::The spontaneous disappearance and reappearance of a ruptured cerebral aneurysm is generally assumed to be a rare phenomenon although the actual incidence is unknown. Among 39 consecutive cases of acute subarachnoid hemorrhage (SAH), 33 were studied by three-dimensional computed tomographic angiography (CTA) within 6 h...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2000.11740723
更新日期:2000-09-01 00:00:00
abstract::Excessive calcium influx has been implicated in the pathophysiology of ischemic cerebral damage. The effects of nimodipine, a calcium antagonist, on the Na(+)-K+/MG+2 ATPase activity, Ca+2/Mg+2 ATPase, lipid peroxidation, and early ultrastructural findings were examined at the acute stage of ischemia in the rat brain....
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198208
更新日期:2001-01-01 00:00:00
abstract::A 52-year-old male underwent lumboperitoneal shunting after external decompressive craniectomy. His postoperative course was accompanied by remarkable displacement of the intracranial structures to the opposite side of craniectomy. This phenomenon, probably caused by the siphon effect of cerebrospinal fluid shunting, ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1991.11739979
更新日期:1991-06-01 00:00:00
abstract:: Objectives : To detect and compare the features of interictal perfusion and volume asymmetry between temporal lobe epilepsy (TLE) patients with and without hippocampal sclerosis (HS). Methods : Sixty-one TLE patients (mean age ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1853988
更新日期:2020-12-15 00:00:00
abstract::We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelming amyloid accumulation in the walls of leptomeningeal and cortical ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164104225017668
更新日期:2004-07-01 00:00:00
abstract::Recent publications have suggested that intra-ocular pressure (IOP) may be an indirect assessment of intra-cranial pressure (ICP). Both IOP and ICP have similar physiologic pressure ranges and similar responses to changes in intra-abdominal, intra-thoracic and aortic pressure. Previous studies have demonstrated the re...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1999.11740925
更新日期:1999-04-01 00:00:00
abstract::Objective: Remote limb ischemic postconditioning (RIPostC) protects the brain from damage induced by transient focal ischemia/reperfusion. However, the underlying mechanism remains unclear. Methods: RIPostC induced by 10 min of occlusion and another 10 min releasing of blood flow for three cycles in the hind limbs was...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1523037
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:Progesterone modulates dopamine (DA) release in corpus striatum. Our objective was to evaluate the effect of the i.c.v injection of the neurosteroid allopregnanolone (ALL), a progesterone metabolite on dopaminergic activity in the corpus striatum of rats under different gonadal hormonal conditions. METHODS:...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X166281
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVES:Daughter aneurysms have been strongly associated with saccular aneurysm rupture. We constructed a mathematical model to help explain this association as a possible hemodynamic mechanism for intracranial saccular aneurysm rupture. METHODS:Our model is based on the assumption that when an aneurysm reaches a s...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X25171
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Traumatic brain injuries (TBIs) cause a substantial burden to the patient, relatives, and the society as a whole. Much experience and knowledge during the last two decades have improved the neurosurgical treatment as well as the outcome. However, there is still much debate on what actually happens when exter...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000227
更新日期:2013-10-01 00:00:00
abstract::Objective: Nowadays, retinal microvascular structures can be investigated using optical coherence tomography angiography (OCTA). We aimed to evaluate the probable vascular changes in the foveal and peripapillary regions of patients with multiple sclerosis (MS).Methods: A total of 20 patients with relapsing remitting m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1726585
更新日期:2020-04-01 00:00:00