Effects of tetrahydrobiopterin on cerebral infarction after transient focal ischemia in rats.

abstract：:Endolymphatic sac tumors are rare, low-grade adenocarcinomas of the petrous bone. These tumors are highly vascularized and surgical removal is often challenging. We present a staged endovascular-neurosurgical approach consisting of stent-assisted angioplasty of the petrous carotid, selective endovascular embolization ...

journal_title：Neurological research

authors： Cohen JE,Spektor S,Valarezo J,Fellig Y,Umansky F

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To determine the functional abnormalities of the Leu89Pro mutation in connexin32 (CX32), which we have previously reported is present within an X-linked dominant Charcot-Marie-Tooth disease family. In this family, male patients were moderately to severely affected. METHODS:We performed immunofluorescence to ...

journal_title：Neurological research

authors： Da Y,Wang W,Liu Z,Chen H,Di L,Previch L,Chen Z

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Alzheimer's disease (AD) is the most common neurodegenerative disease across the world. The major cause of AD is extensive oxidative stress and inflammation in central nervous system (CNS). Vitamin D3 and E are the most known vitamins that control oxidative stress and mitochondrial respiratory function. Th...

journal_title：Neurological research

authors： Mehrabadi S,Sadr SS

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...

journal_title：Neurological research

authors： DeGracia DJ,Kreipke CW,Kayali FM,Rafols JA

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:It is difficult for the treatment of neurologic tumors with current therapies, including glioma. Despite the advances in cancer therapeutics, the outcomes in these patients remain poor and, therefore, new modalities are required. Recent findings have demonstrated that human umbilical cord blood mesenchymal st...

journal_title：Neurological research

authors： Jiao H,Yang B,Guan F,Li J,Shan H,Song L,Hu X,Liang S,Du Y,Jiang C

更新日期：2011-05-01 00:00:00

abstract：:We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelming amyloid accumulation in the walls of leptomeningeal and cortical ...

journal_title：Neurological research

authors： Kalback W,Esh C,Castaño EM,Rahman A,Kokjohn T,Luehrs DC,Sue L,Cisneros R,Gerber F,Richardson C,Bohrmann B,Walker DG,Beach TG,Roher AE

更新日期：2004-07-01 00:00:00

abstract：:We examined the microsurgical anatomy of the supratentorial subarachnoid cisterns with a surgical microscope in 20 brains prepared using the immersion technique. The adult brains were immersed in Ringer's solution and air was injected into the subarachnoid cisterns while the brains remained submerged in solution. We i...

journal_title：Neurological research

authors： Vinas FC,Fandino R,Dujovny M,Chavez V

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:After a spinal cord injury (SCI), most men experience fertility related problems including poor semen quality in which decreased sperm viability and motility, have been proposed to be related to the accessory sex glands dysfunction. In this study, we investigated the probable effects of SCI on the seminal ves...

journal_title：Neurological research

authors： Dashtdar H,Valojerdi MR

更新日期：2008-06-01 00:00:00

abstract：:Refractory status epilepticus (RSE), defined as status epilepticus that fails to respond to the acute administration of two antiepileptic medications, occurs in approximately a third of patients with status epilepticus, and is associated with increased hospital length of stay, mortality, and functional disability. Com...

journal_title：Neurological research

authors： Hocker S,Wijdicks EF,Rabinstein AA

更新日期：2013-03-01 00:00:00

abstract：:To estimate the regional perfusion pressure and possibly the stump pressure during carotid endarterectomy, cerebral blood flow (CBF) measurements including a vasodilatory test were performed preoperatively. CBF was measured by 133Xe inhalation and emission tomography. An intravenous dose of 1g acetazolamide (Diamox) w...

journal_title：Neurological research

authors： Vorstrup S,Boysen G,Brun B,Engell HC

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:Acquired neurological diseases such as severe traumatic brain or spinal cord injury (SCI) cause irreversible disability. Olfactory ensheathing cell (OEC) transplantation has been trialed as a promising SCI treatment. Extracellular vesicles (EVs), which regulate cell-cell interactions, have recently garnered e...

journal_title：Neurological research

authors： Tu YK,Hsueh YH

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:The syntheses of endothelin receptors A and B were previously shown to be upregulated in rat dorsal hippocampus after traumatic brain injury. Here we characterize endothelin receptor A and endothelin receptor B cellular distribution in hippocampus after permanent global brain ischemia and their possible asso...

journal_title：Neurological research

authors： Kreipke CW,Reynolds CA,Schafer PC,Schafer S,Pirooz R,Rafols JA

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Parkinson's disease (PD) is the most common neurodegenerative disease in humans, and an abundance of evidence has implicated apoptosis signaling pathways in the neurodegeneration of PD. The purpose of this study was to assess the role of B-cell lymphoma 2 (Bcl-2)-associated athanogene 5 (BAG5) protein, whic...

journal_title：Neurological research

authors： Ma M,Wang X,Ding X,Jing J,Ma Y,Teng J

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:This study investigated the role of matrix metalloproteinase-9 (MMP-9) in early brain injury after subarachnoid hemorrhage (SAH). METHOD:Sprague-Dawley male rats (n=36) weighing between 250 and 300 g were used. SAH was produced by injecting autologous arterial blood into the pre-chiasmatic cistern. MMP-9 pro...

journal_title：Neurological research

authors： Guo Z,Sun X,He Z,Jiang Y,Zhang X,Zhang JH

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To explore whether intracranial pulse pressure amplitudes relate to arterial pulse pressure amplitudes and whether correlations between time-related changes in intracranial and arterial pulse pressure amplitudes associate with indices of cerebral autoregulation. METHODS:A total of 257 continuous and simultan...

journal_title：Neurological research

authors： Eide PK,Czosnyka M,Sorteberg W,Pickard JD,Smielewski P

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Transient ischemic attack (TIA) with carotid artery disease (CAD) can increase the risk of cognitive decline. However, the neural mechanisms of the disorder remain unclear. The aim of this study was, using diffusion tensor imaging (DTI), to detect microstructural changes in patients with symptomatic CAD pres...

journal_title：Neurological research

authors： Guo J,Wang S,Li R,Chen N,Zhou M,Chen H,Gong Q,He L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is a multi-factorial disease influenced by both genetic and environmental factors. The aim of this case-control study was to determine the association between Endothelial Nitric Oxide Synthase G894T (rs1799983) gene polymorphism and susceptibility to ischemic stroke (IS) in North Indian po...

journal_title：Neurological research

authors： Kumar A,Misra S,Kumar P,Sagar R,Prasad K,Pandit AK,Chakravarty K,Kathuria P,Yadav AK

更新日期：2016-07-01 00:00:00

abstract：:The application of optical spectroscopy for intra-operatively delineating brain tumors has been studied in this paper. The classification of tissue as normal, tumor and boundary is done using the LAMSTAR neural network (NN). The objective is to combine both fluorescence and reflectance as attributes to be used for the...

journal_title：Neurological research

authors： Sivaramakrishnan A,Graupe D

更新日期：2004-09-01 00:00:00

abstract：:The anatomical substrates of the perception of motion have not yet been established in a detailed way on an individual level. The aim of this study was to develop a systematic procedure for mapping the visual cortex using Transcranial Magnetic Stimulation (TMS). The results showed that such an individual and detailed ...

journal_title：Neurological research

authors： d'Alfonso AA,van Honk J,Schutter DJ,Caffé AR,Postma A,de Haan EH

更新日期：2002-04-01 00:00:00

abstract：:The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...

journal_title：Neurological research

authors： Matsui T,Nagafuji T,Mori T,Asano T

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:In this clinical case-control study, we investigated statin treatment in stroke patients on a range of inflammatory effectors in peripheral blood. We focus on RhoA GTPase and its downstream effectors as a future inflammatory target in stroke treatment. METHODS:Data from 10 patients already on statins at stro...

journal_title：Neurological research

authors： Schultz NEØ,Hasseldam H,Rasmussen RS,Vindegaard N,McWilliam O,Iversen HK,Johansen FF

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The predictive effect of blood cell ratio on ischemic event has been widely confirmed. Whether PWR and PNR can assess the risk of endovascular treatment (EVT) is largely unclear. This study aimed to investigate the prognostic value of PNR and PWR in acute ischemic stroke patients treated with EVT...

journal_title：Neurological research

authors： Wang L,Cheng Q,Peng M,Lv D,Zi W,Xu G,Liu X

更新日期：2020-10-01 00:00:00

abstract：:Brain tumours were induced by intracerebral inoculation of beagle puppies with Avian sarcoma virus (ASV) suspension. The inoculation produced solitary or multiple sarcomas in three dogs and intraventricular anaplastic gliomas in four dogs. At the time of the first tumour positive CT-control Iodine-125 seeds (activity ...

journal_title：Neurological research

authors： Ostertag CB,Warnke P,Kleihues P,Bigner DD

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) polymorphisms with the risk factors for AD have not been definitely confirmed. We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G...

journal_title：Neurological research

authors： Jafarian Z,Saliminejad K,Kamali K,Ohadi M,Kowsari A,Nasehi L,Khorram Khorshid HR

更新日期：2018-01-01 00:00:00

abstract：:Neuronal nitric oxide synthase (nNOS) regulates neurogenesis in normal developing brain, but the role of nNOS in neurogenesis in the ischemic brain remains unclear. To investigate the temporal and spatial relationship between cell proliferation of the ependymal/subventricular zone (SVZ), a principal neuroproliferative...

journal_title：Neurological research

authors： Zhang P,Liu Y,Li J,Kang Q,Tian Y,Chen X,Shi Q,Song T

更新日期：2006-01-01 00:00:00

abstract：:Precocious puberty and amenorrhea have been associated with hydrocephalus, but the pathogenesis has not been determined. Approximately 22 cases of amenorrhea, and a few cases of precocious puberty, have been reported in hydrocephalic patients. Shunt treatment leads to initiation and maintenance of normal reproductive ...

journal_title：Neurological research

authors： Abdolvahabi RM,Mitchell JA,Diaz FG,McAllister JP 2nd

更新日期：2000-01-01 00:00:00

abstract：:The intracranial aneurysm, with an estimated occurrence of up to 4% in the general population, belongs among the most dangerous of cerebrovascular diseases. Although less than one-fifth of these cases results in a subarachnoid haemorrhage, the resulting disability and mortality rate is too high. More understanding is ...

journal_title：Neurological research

authors： Duros J,Clark ME,Kufahl RH,Nadvornik P

更新日期：1991-12-01 00:00:00

abstract：:[15O]-water PET was performed on 12 patients with structural lesions for localization of the motor (n = 5), language (receptive and expressive; n = 6), and visual cortex (n = 1). All these patients underwent interactive image-guided surgery using an infrared digitizer and intraoperative electrical stimulation mapping ...

journal_title：Neurological research

authors： Viñas FC,Zamorano L,Mueller RA,Jiang Z,Chugani H,Fuerst D,Muzik O,Mangner TJ,Diaz FG

更新日期：1997-12-01 00:00:00

abstract：:We assessed the effect of a novel calmodulin antagonist, DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) in a spontaneously hypertensive rat (SHR) permanent focal cerebral ischemia. In experiment I, the left middle cerebral ...

journal_title：Neurological research

authors： Takagi K,Sato T,Shirasaki Y,Narita K,Tamura A,Sano K

更新日期：2001-09-01 00:00:00

abstract：:Recovery of motor function following stroke is believed to be supported, at least in part, by functional compensation involving residual neural tissue. The present study used a rodent model of focal ischemia and intracortical microstimulation (ICMS) to examine the behavioral and physiological effects of cortical stimu...

journal_title：Neurological research

authors： Kleim JA,Bruneau R,VandenBerg P,MacDonald E,Mulrooney R,Pocock D

更新日期：2003-12-01 00:00:00