Abstract:
OBJECTIVES:To review the historical development and current status of endovascular techniques used in the treatment of symptomatic vasospasm following aneurysmal subarachnoid hemorrhage. METHODS:This article summarizes the relevant literature on neurointerventional therapy for vasospasm, namely instillation of intraarterial medication (papaverine, nicardipine, verapamil) and transluminal balloon angioplasty. The authors synthesize the available literature with their own experience using the various endovascular modalities to treat vasospasm at high volume cerebrovascular centers. TECHNIQUE:Indications for the use of neurointerventional therapy as well as a summary of the technique for transluminal angioplasty to treat vasospasm as employed by the authors is described. DISCUSSION:Neurointerventional treatment of vasospasm following aneurysmal hemorrhage has been proven to be a safe and successful technique for those patients suffering symptomatic vasospasm refractory to medical management. The techniques contunue to undergo refinement as endovascular technology advances. We currently favor the use of balloon angioplasty over intraarterial antispasmotics due to the increased durability and long-lasting effects of the former and lower risk profile.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Brisman JL,Eskridge JM,Newell DWdoi
10.1179/016164106X152043subject
Has Abstractpub_date
2006-10-01 00:00:00pages
769-76issue
7eissn
0161-6412issn
1743-1328journal_volume
28pub_type
杂志文章,评审abstract::More reliable prediction of outcome would be helpful for clinicians who treat severely head-injured patients. To determine if neural network modeling would improve outcome prediction compared with standard logistic regression analysis and to determine if data available 24 h after severe head injury allows better predi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740813
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X204666
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:We reviewed our most recent work on the protective effect of adenosine A(2A)antagonism in cerebral ischemia. METHODS:Focal ischemia was produced in rats by introducing a nylon monofilament pre-coated with silicone through the external carotid artery to occlude the right MCA at its origin. RESULTS:A(2A) ant...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164105X21913
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20 in mice. METHODS:Mi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000216
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To explore whether intracranial pulse pressure amplitudes relate to arterial pulse pressure amplitudes and whether correlations between time-related changes in intracranial and arterial pulse pressure amplitudes associate with indices of cerebral autoregulation. METHODS:A total of 257 continuous and simultan...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X172167
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVES:The presence of beta-amyloid (betaA) deposition, induction of reactive gliosis and dystrophic neurites, is a characteristic feature of neuritic plaques in Alzheimer's disease. In vitro, betaA-exposed astrocytes become reactive, similar to astrocytes in contact with betaA plaques in vivo. How betaA-exposed re...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X40020
更新日期:2005-07-01 00:00:00
abstract::We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelming amyloid accumulation in the walls of leptomeningeal and cortical ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164104225017668
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:To explore the risk factors for stroke-associated pneumonia (SAP). METHODS:A retrospective research study was carried out to investigate the clinical data of 1435 patients admitted to the neurological intensive care unit at our university hospital between 1 January 2000 and 31 December 2009. RESULTS:A multi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164111X13007856084205
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this study is to use diffusion tensor imaging (DTI) parameters to evaluate cerebral ischemia/reperfusion injury in the infarct core (IC) and ischemic penumbra (IP) in a rhesus transient middle cerebral artery occlusion (MCAO) model. METHODS:Seven rhesus monkeys were used to construct the MCAO...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12761752770177
更新日期:2011-01-01 00:00:00
abstract::The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199388
更新日期:2001-12-01 00:00:00
abstract::L-644,711 is a novel anion channel inhibitor which has previously been shown to decrease brain injury in two related rabbit models of cerebral ischaemia. We hypothesize two mechanisms of action of L-644,711 for its salutary effects on cerebral ischaemia: inhibition of neutrophil function and prevention of excitotoxin ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1992.11740011
更新日期:1992-03-01 00:00:00
abstract::Objective: To assess the neuropsychological status of pediatric multiple sclerosis (MS) patients and its relationship with clinical variables in a longitudinal study.Methods: Patients with MS (n = 46) and age- and gender-matched healthy control subjects (HCs, n = 53) were given tests of non-verbal reasoning, attention...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2019.1710417
更新日期:2020-02-01 00:00:00
abstract::Different surgical approaches exist for the treatment of chronic subdural hematoma. None of these approaches is superior to the other, so a minimal-invasive device (a hollow screw) was developed. The system consists of a stable hollow screw of surgical steel with a perforated tip, a hand-drill, screwdriver with guide,...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1999.11740897
更新日期:1999-01-01 00:00:00
abstract::Six cases of very large anterior circulation intracranial aneurysms are presented. Aneurysms of 53-84 mm in three female and two male adults and a 40 mm lesion in a seven week infant were successfully excised. Three patients tolerated trial intraluminal balloon occlusion preoperatively and underwent subsequent parent ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1992.11740053
更新日期:1992-01-01 00:00:00
abstract::The object of the study was to evaluate brain tissue oxygenation (p(ti)O2) for intra-operative monitoring of critical ischemic events during early cerebral aneurysm surgery of the anterior circulation supplementary to somatosensory evoked potentials (SEPs). P(ti)O2 was continuously evaluated during surgery for an intr...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1179/016164102101200528
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:This study examined whether a needle-free acupuncture can be an alternative to conventional needle injection acupuncture. METHODS:Patients (n=101) suffering myofascial shoulder pain were randomly assigned to either needle-free or conventional needle injection acupuncture group. Bee venom was administered int...
journal_title:Neurological research
pub_type: 杂志文章,随机对照试验
doi:10.1179/016164109X12537002793760
更新日期:2010-02-01 00:00:00
abstract::Objective: To determine the time of dementia diagnosis, symptom intensity and to assess the comorbidities.Methods: 110 patients with dementia or mild cognitive impairment were enrolled in this retrospective study. The study group was divided into subgroups: patients with a maximum of three (S ≤ 3 n = 62) and four or m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1738648
更新日期:2020-05-01 00:00:00
abstract::Recent work has suggested that one factor in the etiology of the neuromuscular disease, amyotrophic lateral sclerosis (ALS), may be an autoimmune mechanism in which presynaptic voltage-sensitive calcium channels are an antigenic target. We have developed a fluorescence technique to measure rapid Ca2+ influx through pr...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740785
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVES:Daughter aneurysms have been strongly associated with saccular aneurysm rupture. We constructed a mathematical model to help explain this association as a possible hemodynamic mechanism for intracranial saccular aneurysm rupture. METHODS:Our model is based on the assumption that when an aneurysm reaches a s...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X25171
更新日期:2005-07-01 00:00:00
abstract::Following cerebral ischemia, the extracellular concentration of excitatory amino acids increases, and the excitatory cell death may play an important role contributing to ischemic neuronal damage. Although sequential metabolic changes in permanent local cerebral ischemia have been reported, the effect of reperfusion i...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1996.11740462
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:This review will describe the novel contributions to the field of nerve repair from the emerging disciplines of microtechnology and nanotechnology. METHOD:This broad review will cover the advances described in the literature of the medical and biological fields and the engineering and physical sciences. The ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/174313208X362532
更新日期:2008-12-01 00:00:00
abstract::Background The distribution of risk factors for stroke is related to gender and age. The main objective of study was to determine the type and frequency of stroke risk factors in patients with first-in-life stroke before the age of 50. Methods Our study included patients under the age of 50 with first-in-life stroke. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2018.1455367
更新日期:2018-07-01 00:00:00
abstract::The haemodynamic mechanisms responsible for the appearance of paraparetic transient ischaemic attacks in ten patients with childhood moyamoya disease who subsequently underwent bifrontal omental transplantation were investigated. Cerebral perfusion (CP) was measured with 99mTc-hexamethylene-propyleneamine oxime single...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1995.11740306
更新日期:1995-06-01 00:00:00
abstract::It has been established that following injury to the central nervous system two types of damage take place, the initial insult and the secondary response to injury. This review will focus on the secondary molecular aspects of neurotrauma. These responses may be either deleterious or have protective effects upon the in...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164101101198343
更新日期:2001-03-01 00:00:00
abstract::Predictions from a structured cortical model led us to test the hypothesis that music training enhances young children's spatial-temporal reasoning. Seventy-eight preschool children participated in this study. Thirty-four children received private piano keyboard lessons, 20 children received private computer lessons, ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740765
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:Crossed-uncrossed differentials (CUDs) are viewed as surrogates for interhemispheric transfer time (IHTT). Not uncommonly CUDs assume statistically significant negative values (inverted CUDs). This raises doubts of the accepted interpretation of CUDs, i.e. intra- and inter-hemispheric routings of signals in ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164106X115107
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Traumatic brain injuries (TBIs) cause a substantial burden to the patient, relatives, and the society as a whole. Much experience and knowledge during the last two decades have improved the neurosurgical treatment as well as the outcome. However, there is still much debate on what actually happens when exter...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000227
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1209337
更新日期:2016-09-01 00:00:00
abstract::The present study used immunohistochemistry to investigate p53 expression in rat brain following transient occlusion of the middle cerebral artery. In the control group, no p53-immunoreactive cells were found in any region of the central nervous system. P53 expression in reactive astrocytes was not obvious in the fore...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164102101199828
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:4-N-trimethylammonium-3-hydroxybutyric acid (L-carnitine) is an endogenous mitochondrial membrane compound and some studies have reported that L-carnitine could effectively protect various cells against oxidative injury both in vitro and in vivo. In the present study, we used the human neuroblastoma SH-SY5Y ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132810Y.0000000028
更新日期:2011-09-01 00:00:00