Loss of essential membrane lipids and ascorbic acid from rat brain following cryogenic injury and protection by methylprednisolone.

abstract：OBJECTIVE:It is not fully understood how the stimulus/response curves obtained by transcranial magnetic stimulation (TMS) reflect the function of the cortico-motoneuronal (CM) and spinal motoneuronal (SM) systems in healthy subjects. To understand these response functions, we studied patients with amyotrophic lateral s...

journal_title：Neurological research

authors： Oishi A,Tobimatsu S,Ogata K,Taniwaki T,Kinukawa N,Toyoshiba H,Kira J

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker that is associated with the outcomes of ischemic stroke. However, the role of hs-CRP levels in the functional outcomes after large-artery atherosclerosis (LAA) and small-artery occlusion (SAO) is poorly understood. METHODS:We recruited 1...

journal_title：Neurological research

authors： Hou D,Liu J,Feng R,Gao Y,Wang Y,Wu J

更新日期：2017-11-01 00:00:00

abstract：:Mountain trekking is significantly increasing in popularity. Hypoxia seems to play a key role in the pathogenesis of acute mountain sickness (AMS). The purpose of this study was to investigate regional cerebral (rSO2) and peripheral (SaO2) oxygen saturation for the first time, during 22 days high altitude trekking (me...

journal_title：Neurological research

authors： Hadolt I,Litscher G

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:To review the use of immunoassays in the diagnosis and research of disorders affecting the nervous system. METHODS:Systematic review of the English literature. RESULTS:Immunoassays have demonstrated utility for: (1) the detection of antigen (molecules, genes, gene products, peptides, hormones and drug meta...

journal_title：Neurological research

authors： Meriggioli MN

更新日期：2005-10-01 00:00:00

abstract：:Background: IVS5-91G>A (rs3812718) polymorphism of the sodium voltage-gated channel alpha subunit 1 (SCN1A) gene has been associated with inadequate responsiveness to common antiepileptic drugs which act as sodium channel blockers. This study was performed to investigate the effect of IVS5-91G>A (rs3812718) polymorphi...

journal_title：Neurological research

authors： Markovic I,Pejanovic-Skobic N,Bozina N,Susak Sporis I,Sporis D,Basic S

更新日期：2019-10-01 00:00:00

abstract：:Various surgical approaches have been described for treating lesions which arise in the sellar region. The popular transnasal-transsphenoidal and transethmoidal-transsphenoidal approaches avoid the morbidity associated with transcranial operations while allowing enough exposure to successfully remove most lesions that...

journal_title：Neurological research

authors： Das K,Spencer W,Nwagwu CI,Schaeffer S,Wenk E,Weiss MH,Couldwell WT

更新日期：2001-01-01 00:00:00

abstract：:Regional glucose utilization was measured in the rat brain after occlusion of the middle cerebral artery. Normoglycaemic rat had increased glucose use in the cerebral cortex adjacent to the infarct. A fraction of the nerve cells were irreversibly injured in this region. In hyperglycaemic rats, the glucose metabolism r...

journal_title：Neurological research

authors： Nedergaard M,Gjedde A,Diemer NH

更新日期：1987-12-01 00:00:00

abstract：:We examined antioxidant activity of cabergoline, a dopamine agonist, during the aerobic oxidation of phosphatidylcholine liposomes at 37 degrees C. Cabergoline retarded the oxidation initiated with a lipid-soluble initiator significantly better than that with a water-soluble initiator, suggesting that cabergoline loca...

journal_title：Neurological research

authors： Sohmiya M,Tanaka M,Okamoto K,Fujisawa A,Yamamoto Y

更新日期：2004-06-01 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy (31P-MRS) was made to measure changes in brain high energy phosphate compounds, adenosine triphosphate (ATP) and phosphocreatine (PCr), inorganic phosphorus (Pi) and intracellular pH (pHi) during a prolonged period of incomplete brain ischaemia produced, in anaesthetized dogs...

journal_title：Neurological research

authors： Anderson ML,Smith DS,Nioka S,Subramanian H,Garcia JH,Halsey JH,Chance B

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...

journal_title：Neurological research

authors： Rijbroek A,Boellaard R,Vriens EM,Lammertsma AA,Rauwerda JA

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:This study intends to investigate the prognostic value of perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage. METHODS:Demographic, clinical and biochemical data between acute intracerebral hemorrhage (AICH) and healthy volunteer groups were assessed in this study, such as rCBV an...

journal_title：Neurological research

authors： Hu X,Bai X,Zai N,Sun X,Zhu L,Li X

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:This study investigated the role of matrix metalloproteinase-9 (MMP-9) in early brain injury after subarachnoid hemorrhage (SAH). METHOD:Sprague-Dawley male rats (n=36) weighing between 250 and 300 g were used. SAH was produced by injecting autologous arterial blood into the pre-chiasmatic cistern. MMP-9 pro...

journal_title：Neurological research

authors： Guo Z,Sun X,He Z,Jiang Y,Zhang X,Zhang JH

更新日期：2010-09-01 00:00:00

abstract：:This study was performed to test whether GYKI 52466, a nonNMDA receptor antagonist, would improve microregional oxygen supply and consumption balance in the focal cerebral ischemic area. Rats were anesthetized with 1.4% isoflurane. For the GYKI Group (n = 8), 10 min before middle cerebral artery (MCA) occlusion, a bol...

journal_title：Neurological research

authors： Chi OZ,Chang Q,Wang G,Liu X,Weiss HR

更新日期：1999-04-01 00:00:00

abstract：:There have been reports that superior cervical ganglionectomy (SCG) is effective as a treatment for cerebral vasospasm following subarachnoid haemorrhage (SAH). On the other hand, denervation supersensitivity is supposed to play an important role in vasospasm. The two accounts contradict each other. To investigate thi...

journal_title：Neurological research

authors： Iwai R,Kamiyama K,Nagahori T,Ohtsuji T,Endo S,Takaku A

更新日期：1988-09-01 00:00:00

abstract：:The possibility of the evaluation of ischemia solely by the momentary values of regional cerebral blood flow (rCBF) was investigated. Ischaemic damage was evaluated histopathologically and by observing albumin extravasation. Unilateral carotid clippings were performed for 1 h and the gerbils evaluated with regard to t...

journal_title：Neurological research

authors： Kadota E

更新日期：1988-12-01 00:00:00

abstract：:The anatomical substrates of the perception of motion have not yet been established in a detailed way on an individual level. The aim of this study was to develop a systematic procedure for mapping the visual cortex using Transcranial Magnetic Stimulation (TMS). The results showed that such an individual and detailed ...

journal_title：Neurological research

authors： d'Alfonso AA,van Honk J,Schutter DJ,Caffé AR,Postma A,de Haan EH

更新日期：2002-04-01 00:00:00

abstract：:Precocious puberty and amenorrhea have been associated with hydrocephalus, but the pathogenesis has not been determined. Approximately 22 cases of amenorrhea, and a few cases of precocious puberty, have been reported in hydrocephalic patients. Shunt treatment leads to initiation and maintenance of normal reproductive ...

journal_title：Neurological research

authors： Abdolvahabi RM,Mitchell JA,Diaz FG,McAllister JP 2nd

更新日期：2000-01-01 00:00:00

abstract：:The mechanism of cerebral ischaemic injury is complex and likely involves more than a single pathophysiologic event. Drugs are available which interfere with numerous harmful biochemical and pharmacologic processes begun by ischaemia. Hence, combination chemotherapy might be useful in cerebral ischaemia. The purpose o...

journal_title：Neurological research

authors： Auer RN

更新日期：1995-04-01 00:00:00

abstract：:To investigate the migration of neural stem cells as well as neural plastic changes in epileptic brain, spaciotemporal expression of immunoreactive highly polysialylated neural cell adhesion molecule (PSA-NCAM) was examined in amygdala kindling development of rat. The neural migration and synaptic remodeling detected ...

journal_title：Neurological research

authors： Sato K,Iwai M,Nagano I,Shoji M,Abe K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Diabetes is one of the major risk factors for ischemic stroke and is reported to aggravate the ischemic brain damage in different experimental models as well as clinical situations. However, the mechanisms underlying the exacerbated ischemia/reperfusion (I/R) brain injury associated with comorbid diabetes ar...

journal_title：Neurological research

authors： Srinivasan K,Sharma SS

更新日期：2011-10-01 00:00:00

abstract：:Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...

journal_title：Neurological research

authors： Nagasawa S,Kawanishi M,Tanaka H,Ohta T,Nagayasu S,Kikuchi H

更新日期：1993-12-01 00:00:00

abstract：:The possible role of nitric oxide (NO) on vibrissa-stimulated increase of regional cerebral cerebral blood flow (rCBF) and cerebral metabolic rate of glucose (rCMRglu) was investigated in conscious Wistar rats by using an inhibitor of NO synthase, NG-nitro-L-arginine (NOLAG) at a concentration of 30 mg/kg. In vivo aut...

journal_title：Neurological research

authors： Wang Q,Kjaer T,Jørgensen MB,Paulson OB,Lassen NA,Diemer NH,Lou HC

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China. SUBJECTS AND METHODS:A cross-sectional study (across 19 urban outpatient clinics) on secondary stroke prevention measures w...

journal_title：Neurological research

authors： Wang Y,Wu D,Zhou Y,Zhao X,Wang C,Liu L,Liao X,Wang Y

更新日期：2008-05-01 00:00:00

abstract：:Although rat models implanted with C6 glioma cells have been widely utilized for the assessment of new therapeutic modalities, a convenient in vivo model is still required. We implanted C6 glioma cells into the brains and the abdominal subcutaneous regions of Wistar rats, and evaluated the volumes of the growing tumor...

journal_title：Neurological research

authors： Watanabe K,Sakamoto M,Somiya M,Amin MR,Kamitani H,Watanabe T

更新日期：2002-07-01 00:00:00

abstract：:The effect of labetalol, a combined alpha- and beta-adrenoceptor antagonist, on the cerebral circulation was investigated in 7 normotensive subjects. Cerebral blood flow (CBF) was measured with the intravenous 133Xe method and mean flow velocity (Vmean) in the middle cerebral artery was determined using transcranial D...

journal_title：Neurological research

authors： Schroeder T,Schierbeck J,Howardy P,Knudsen L,Skafte-Holm P,Gefke K

更新日期：1991-03-01 00:00:00

abstract：:This paper presents the results of transsphenoidal surgery in 41 consecutive patients with visual loss from pituitary adenomas. The most common pattern of loss was bitemporal hemianopia. Transsphenoidal decompression resulted in visual improvement in 78% of patients. If patients with optic atrophy and pre-operative co...

journal_title：Neurological research

authors： el-Azouzi M,Black PM,Candia G,Zervas NT,Panagopoulos KP

更新日期：1990-03-01 00:00:00

abstract：:To estimate the regional perfusion pressure and possibly the stump pressure during carotid endarterectomy, cerebral blood flow (CBF) measurements including a vasodilatory test were performed preoperatively. CBF was measured by 133Xe inhalation and emission tomography. An intravenous dose of 1g acetazolamide (Diamox) w...

journal_title：Neurological research

authors： Vorstrup S,Boysen G,Brun B,Engell HC

更新日期：1987-03-01 00:00:00

abstract：:A new suction device for microneurosurgery is presented. A surgical cottonoid is covered with a polyethylene film so that vacuum power is maintained throughout the length of the cottonoid. One end is connected to a vacuum pump via a plastic tube. Five to 10 mm of the surgical cottonoid are exposed for suctioning at th...

journal_title：Neurological research

authors： Sakatani K,Zuo H

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Ischemic stroke is one of the most common causes of death worldwide. Early and accurate prediction of outcome in acute ischemic stroke (AIS) is important and influences risk-optimized therapeutic strategies. We investigated the changes in high-sensitivity C-reactive protein (Hs-CRP) and homocysteine (HCY) le...

journal_title：Neurological research

authors： Tu WJ,Zhao SJ,Liu TG,Yang DG,Chen H

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) polymorphisms with the risk factors for AD have not been definitely confirmed. We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G...

journal_title：Neurological research

authors： Jafarian Z,Saliminejad K,Kamali K,Ohadi M,Kowsari A,Nasehi L,Khorram Khorshid HR

更新日期：2018-01-01 00:00:00