Effect of labetalol on cerebral blood flow and middle cerebral arterial flow velocity in healthy volunteers.

abstract：OBJECTIVES:The purpose of this study was to investigate the ability of bone marrow mesenchymal stem cells (BMSCs) to survive in the striatum and improve motor function in the quinolinic acid (QA) lesion rat model of Huntington's disease (HD). METHODS:One week following QA lesioning of the striatum, rats were transplan...

journal_title：Neurological research

authors： Jiang Y,Lv H,Huang S,Tan H,Zhang Y,Li H

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:4-N-trimethylammonium-3-hydroxybutyric acid (L-carnitine) is an endogenous mitochondrial membrane compound and some studies have reported that L-carnitine could effectively protect various cells against oxidative injury both in vitro and in vivo. In the present study, we used the human neuroblastoma SH-SY5Y ...

journal_title：Neurological research

authors： Yu J,Ye J,Liu X,Han Y,Wang C

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:In order to avoid occurrence of post-operative hygromas in specific hydrocephalus patients being at high risk of overdrainage, a combination of programmable valve and anti-gravity device is widely recommended. We analyzed our series of hydrocephalus patients implanted with such a shunt configuration focusin...

journal_title：Neurological research

authors： Zachenhofer I,Donat M,Roessler K

更新日期：2012-04-01 00:00:00

abstract：:The successful treatment of an intracranial arteriovenous malformation poses both technical and conceptual problems to the neurosurgeon. Treatment decisions are made in light of current understanding of the natural history of these lesions. It is important to understand the pros, cons and current indication of open cr...

journal_title：Neurological research

authors： Surdell DL Jr,Bhattacharjee S,Loftus CM

更新日期：2002-06-01 00:00:00

abstract：:Until recently, endovascular management of intracranial aneurysms has focused on mechanical and hemodynamic aspects: characterizing aneurysm morphology by angiogram, mechanical obstruction by detachable coils, and flow diversion with endovascular stents. Although now common practice, these interventions only ward off ...

journal_title：Neurological research

authors： Esfahani DR,Viswanathan V,Alaraj A

更新日期：2015-03-01 00:00:00

abstract：:Promyelocytic leukemia (PML) protein is involved in apoptotic death of cultured neuronal cells, but its role in ischemic brain damage remains uncertain. In this study, we investigated change of immunoreactivity for PML protein in rat brain after transient middle cerebral artery occlusion, and compared the results with...

journal_title：Neurological research

authors： Hayashi T,Sasaki C,Iwai M,Sato K,Zhang WR,Warita H,Abe K

更新日期：2001-10-01 00:00:00

abstract：:Serial magnetic resonance (MR) imaging has not yet been validated in the therapy of experimental intracerebral hematomas in a rat model. It is possible to test the effect of local fibrinolysis and aspiration on the clot volume using serial magnetic resonance imaging and different MR-sequences. Experiments were carried...

journal_title：Neurological research

authors： Deinsberger W,Hartmann M,Vogel J,Jansen O,Kuschinsky W,Sartor K,Böker DK

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...

journal_title：Neurological research

authors： DeGracia DJ,Kreipke CW,Kayali FM,Rafols JA

更新日期：2007-06-01 00:00:00

abstract：:Objective The aim of the study was to evaluate the parameters for localizing the seizure onset zone in refractory epilepsy patients using cortico-cortical evoked potentials (CCEP). Methods Fifteen patients (nine females) with medically refractory partial epilepsy underwent stereo electro encephalography (SEEG) in Tsin...

journal_title：Neurological research

authors： Zhang N,Zhang B,Rajah GB,Geng X,Singh R,Yang Y,Yan X,Li Z,Zhou W,Ding Y,Sun W

更新日期：2018-06-01 00:00:00

abstract：:The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and a...

journal_title：Neurological research

authors： Robertson J,Timmons S

更新日期：2007-10-01 00:00:00

abstract：:This study was designed to evaluate the effects of two consecutive ischaemias on extracellular monoaminergic neurotransmitter concentrations. The data on the neuroamine changes induced by the second ischaemia could be used to assess the delay in aminergic neurotransmission subsequent to the primary injury. Dopamine (D...

journal_title：Neurological research

authors： Decombe R,Bentué-Ferrer D,Allain H,Van den Driessche J

更新日期：1993-06-01 00:00:00

abstract：:Twenty-four patients presenting an acute stroke with watershed cerebral infarct on CT scan or MRI were included in this retrospective study. Age was 63 +/- 14 years (mean +/- SD), and sex ratio was 2 men for 1 woman. Main clinical features were: in anterior location, lower limb weakness and frontal syndrome with trans...

journal_title：Neurological research

authors： Evrard S,Woimant F,Le Coz P,Polivka M,Cousin C,Haguenau M

更新日期：1992-01-01 00:00:00

abstract：:We examined regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO2) in 10 patients with progressive dementia and amyotrophic lateral sclerosis (DALS), in 21 patients with classical amyotrophic lateral sclerosis without dementia (ALS), and in 17 controls. The mean rCBF and rCMRO2, especially in the anterior ...

journal_title：Neurological research

authors： Tanaka M,Ichiba T,Kondo S,Hirai S,Okamoto K

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...

journal_title：Neurological research

authors： Rijbroek A,Boellaard R,Vriens EM,Lammertsma AA,Rauwerda JA

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Acquired neurological diseases such as severe traumatic brain or spinal cord injury (SCI) cause irreversible disability. Olfactory ensheathing cell (OEC) transplantation has been trialed as a promising SCI treatment. Extracellular vesicles (EVs), which regulate cell-cell interactions, have recently garnered e...

journal_title：Neurological research

authors： Tu YK,Hsueh YH

更新日期：2020-11-01 00:00:00

abstract：:We have reliable data on the degree of stenosis above which endarterectomy for symptomatic carotid stenosis is beneficial, but benefit is also influenced by other factors, particularly age, sex, the timing of surgery, plaque surface morphology and the nature of the presenting symptomatic event(s). This review will con...

journal_title：Neurological research

authors： Rothwell PM

更新日期：2005-01-01 00:00:00

abstract：:Cerebral hemorrhages are subject to a heavy short- and long-term case fatality. A study of prognostic factors and of relative survival based on the data of a population registry is of great value to study patients having a hematoma of all ages, irrespective of the method of care. We have listed 183 patients having a c...

journal_title：Neurological research

authors： el Chami B,Milan C,Giroud M,Sautreaux JL,Faivre J

更新日期：2000-12-01 00:00:00

abstract：:Refractory status epilepticus (RSE), defined as status epilepticus that fails to respond to the acute administration of two antiepileptic medications, occurs in approximately a third of patients with status epilepticus, and is associated with increased hospital length of stay, mortality, and functional disability. Com...

journal_title：Neurological research

authors： Hocker S,Wijdicks EF,Rabinstein AA

更新日期：2013-03-01 00:00:00

abstract：:Acute presentation of Type I Chiari malformation in children is distinctly rare. An 11 year old male suffered a trauma to the right temporal-parietal region in a tobogganing accident resulting in an open depressed skull fracture. Radiographic evaluation included a Computed Tomographic scan which also demonstrated a si...

journal_title：Neurological research

authors： Couldwell WT,Zhang W,Allen R,Arce D,Stillerman CB

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is a major risk factor for stroke and all of its pathological subtypes including subarachnoid hemorrhage (SAH). However, there is little evidence demonstrating whether failure to have regular BP measured could result in underestimation of people at risk for SAH. Therefore, we aimed ...

journal_title：Neurological research

authors： Shiue I,Hankey GJ,Arima H,Anderson CS

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:Occipital petalia is an anatomic description where one of the occipital lobes protrudes towards the contralateral side. Transverse sinus (TS) asymmetry might cause diagnostic challenges with regards to thrombotic or compressive pathologies involving these sinuses. In this study, we investigated the associati...

journal_title：Neurological research

authors： Arsava EY,Arsava EM,Oguz KK,Topcuoglu MA

更新日期：2019-04-01 00:00:00

abstract：:Background: Surgery of parasagittal meningiomas (PSMs) is still technically challenging, for the balance between radical resection and preservation of venous circulation. In this article, we'd systemically introduce the technical nuances of a simplified strategy for radical resection of all types of PSMs. All the case...

journal_title：Neurological research

authors： Zhang N,Yang T,Hameed F,Zhang X,Yao Y,Li D,Li C,Yu S,Xu Y,Xia C,Fu X

更新日期：2020-11-11 00:00:00

abstract：OBJECTIVES:In the present study, we investigated the effects of treadmill exercise on microglial activation and the subsequent release of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6 and IL-1-beta in the hippocampus in a rat model of type 2 diabetes. METHODS:At 30 weeks of age, diabetic (Zucker diabeti...

journal_title：Neurological research

authors： Yoo DY,Chae J,Jung HY,Yim HS,Kim JW,Nam SM,Kim DW,Choi JH,Seong JK,Yoon YS,Hwang IK

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To explore the risk factors for stroke-associated pneumonia (SAP). METHODS:A retrospective research study was carried out to investigate the clinical data of 1435 patients admitted to the neurological intensive care unit at our university hospital between 1 January 2000 and 31 December 2009. RESULTS:A multi...

journal_title：Neurological research

authors： Sui R,Zhang L

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Tissue plasminogen activator (tPA) may aggravate ischemic neuronal damage after focal cerebral ischemia and increase blood-brain barrier permeability. Human serum albumin has neuroprotective effects on ischemic stroke. However, whether albumin can attenuate the deleterious effects of tPA is yet unknown. METH...

journal_title：Neurological research

authors： Tang J,Li YJ,Mu J,Li Q,Yang DY,Xie P

更新日期：2009-03-01 00:00:00

abstract：:Dementia is one of the commonest neurological disorders in the elderly population. In regards to the increasing longevity of populations worldwide, prevention of dementia has become a major public health challenge. There has been an intense research in the identification of modifiable risk factors for dementia. These ...

journal_title：Neurological research

authors： Bergmann C,Sano M

更新日期：2006-09-01 00:00:00

abstract：:The present study used immunohistochemistry to investigate p53 expression in rat brain following transient occlusion of the middle cerebral artery. In the control group, no p53-immunoreactive cells were found in any region of the central nervous system. P53 expression in reactive astrocytes was not obvious in the fore...

journal_title：Neurological research

authors： Chung YH,Shin CM,Kim MJ,Lee EY,Kim G,Cha CI

更新日期：2002-04-01 00:00:00

abstract：:This study was designed to assess the effects of volume expansion with Fluosol-DA and hetastarch on local cerebral blood flow (CBF), cortical O2 availability (O2a) and computerized EEG power data during cerebral ischaemia in a primate stroke model. Focal cerebral ischaemia was produced in 20 anaesthetized Macaca monke...

journal_title：Neurological research

authors： Tranmer BI,Iacobacci R,Feiler S

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) polymorphisms with the risk factors for AD have not been definitely confirmed. We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G...

journal_title：Neurological research

authors： Jafarian Z,Saliminejad K,Kamali K,Ohadi M,Kowsari A,Nasehi L,Khorram Khorshid HR

更新日期：2018-01-01 00:00:00

abstract：:This study examined the changes in cerebral blood flow, water content, and lipoxygenase metabolites (leukotrienes) following bilateral carotid artery occlusion (BCO) and reperfusion in the gerbil. The effect of inhibiting lipoxygenase with nordihydroguaretic acid (NDGA) was also examined. BCO caused cerebral blood flo...

journal_title：Neurological research

authors： Dempsey RJ,Roy MW,Cowen DE,Maley ME

更新日期：1986-03-01 00:00:00