Enhanced expression of p53 in reactive astrocytes following transient focal ischemia.

abstract：:Objectives: Brain arteriovenous malformations (AVMs) represent high-flow vascular lesions made up of a complex network of feeding arteries and draining veins interposed by a nidus and without a capillary bed. The management of the AVMs represents a challenge, and the optimal treatment should be considered based on the...

journal_title：Neurological research

authors： Gorgan RM,Petrescu GED,Brehar FM

更新日期：2020-12-01 00:00:00

abstract：:The present study was designed to investigate the beneficial effects of cornel iridoid glycoside (CIG), a main component extract from Cornus officinalis, on neurotrophin expression in mouse experimental autoimmune encephalomyelitis (EAE), a classical model of multiple sclerosis (MS). After EAE initiation, CIG was intr...

journal_title：Neurological research

authors： Qu Z,Zheng N,Zhang Y,Zhang L,Liu J,Wang Q,Yin L

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Neuropsychological outcomes after carotid endarterectomy (CEA) have been investigated extensively. However, cognitive impacts of carotid angioplasty and stenting (CAS), an emerging alternative to CEA, have not been studied. This study is aimed at investigating pattern and degree of cognitive changes after CAS...

journal_title：Neurological research

authors： Xu G,Liu X,Meyer JS,Yin Q,Zhang R

更新日期：2007-04-01 00:00:00

abstract：:The objective of this study was to determine, whether 0.5-2/min oscillations in intracranial pressure ('B-waves') are a physiological phenomenon. In a group of 5 patients 0.5-2/min oscillations of ventricular pressure simultaneous with oscillations in the middle cerebral artery (MCA) flow velocity, as assessed by tran...

journal_title：Neurological research

authors： Mautner-Huppert D,Haberl RL,Dirnagl U,Villringer A,Schmiedek P,Einhäupl K

更新日期：1989-12-01 00:00:00

abstract：:Mild vascular cognitive impairment (mVCI) is a broader term that is intended to detect cognitive loss before the development of dementia. The identification of preventable risk factors as well as therapeutic strategies of intervention is still unclear. It has been suggested that carotid endarterectomy (CEA) improves c...

journal_title：Neurological research

authors： Borroni B,Tiberio G,Bonardelli S,Cottini E,Facheris M,Akkawi N,Pezzini A,Cervi E,Giulini SM,Padovani A

更新日期：2004-07-01 00:00:00

abstract：:The object of the study was to evaluate brain tissue oxygenation (p(ti)O2) for intra-operative monitoring of critical ischemic events during early cerebral aneurysm surgery of the anterior circulation supplementary to somatosensory evoked potentials (SEPs). P(ti)O2 was continuously evaluated during surgery for an intr...

journal_title：Neurological research

authors： Szelényi A,Jung CS,Schön H,Seifert V

更新日期：2002-09-01 00:00:00

abstract：:The treatment of arteriovenous malformations depends on the efforts of a multidisciplinary team whose ultimate goal is to achieve better results when compared to the natural history of the pathology. The role of adjuvant treatment modalities such as radiosurgery and endovascular embolization is discussed. Treatment st...

journal_title：Neurological research

authors： de Oliveira E,Tedeschi H,Raso J

更新日期：1998-12-01 00:00:00

abstract：:Sixty-five years old patient suffering from acute stroke was treated by rTPA intravenously. TCD monitoring of both middle cerebral arteries (MCA) was carried out simultaneously with administration of rTPA. Seven microemboli were found in right and four in left MCA. Duplex ultrasound, CT angiography and digital subtrac...

journal_title：Neurological research

authors： Telman G,Kouperberg E,Eran A,Goldsher D,Yarnitsky D

更新日期：2008-09-01 00:00:00

abstract：:Brain tumours were induced by intracerebral inoculation of beagle puppies with Avian sarcoma virus (ASV) suspension. The inoculation produced solitary or multiple sarcomas in three dogs and intraventricular anaplastic gliomas in four dogs. At the time of the first tumour positive CT-control Iodine-125 seeds (activity ...

journal_title：Neurological research

authors： Ostertag CB,Warnke P,Kleihues P,Bigner DD

更新日期：1984-12-01 00:00:00

abstract：:No marker that predicts accurately the time of occurrence of cerebral vasospasm due to subarachnoid hemorrhage (SAH) has been reported. In the present study, membrane-bound tissue factor (mTF) and myelin basic protein (MBP) concentrations in cerebrospinal fluid (CSF) were evaluated as a predictor of the time of occurr...

journal_title：Neurological research

authors： Hirashima Y,Endo S,Nakamura S,Kurimoto M,Takaku A

更新日期：2001-10-01 00:00:00

abstract：:Neuronal nitric oxide synthase (nNOS) regulates neurogenesis in normal developing brain, but the role of nNOS in neurogenesis in the ischemic brain remains unclear. To investigate the temporal and spatial relationship between cell proliferation of the ependymal/subventricular zone (SVZ), a principal neuroproliferative...

journal_title：Neurological research

authors： Zhang P,Liu Y,Li J,Kang Q,Tian Y,Chen X,Shi Q,Song T

更新日期：2006-01-01 00:00:00

abstract：:It is known that mitochondrial ATP-sensitive potassium channels (mitoKATP) play a significant role in protecting cerebral function from ischemia-reperfusion injury, which is related with a decrease in the mitochondrial matrix calcium. However, the effect of mitochondrial calcium uniporter (MCU) on diazoxide-induced ce...

journal_title：Neurological research

authors： Zhang L,Wang S,Dong H,Li Y,Wang P,Li S,Guo Y,Yao R

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, characterized by a selective progressive degeneration of the motor system. Electromyography is essential for the diagnosis of ALS. The measurement of motor conduction of peripheral nerves is of major importance to recognize other poss...

journal_title：Neurological research

authors： Mohammadi B,Krampfl K,Kollewe K,Seyfadini A,Bufler J,Dengler R

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Surgical resection of complex glomus vagale tumors can be complicated by extensive blood loss and might require surgical sacrifice of an encased internal carotid artery. METHODS:A young patient presented with mass effect from glomus valage tumor. Computerized tomography angiography showed an encased interna...

journal_title：Neurological research

authors： Alaraj A,Pytynia K,Carlson AP,Krishna PH,Charbel FT,Amin-Hanjani S,Aletich V

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical application of adjuvant coiling techniques in treating anterior-circulation wide-necked aneurysms. METHODS:Over 4·5 years, 93 anterior-circulation wide-neck aneurysms in 81 patients were treated with different endovascular techniques: balloon-assisted, stent-assisted, and double-m...

journal_title：Neurological research

authors： Pan J,Xiao F,Szeder V,Yan M,Fan W,Gu J,He L,Zhan R

更新日期：2013-12-01 00:00:00

abstract：:This paper summarizes the work of developing and analyzing a mathematical model of schizophrenia. First the psychological and physiological studies of patients with periodic catatonia made by R. R. Gjessing are briefly described. Then a mathematical model, which is based on Gjessing's work and consists of a set of non...

journal_title：Neurological research

authors： Cronin J

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:To find new biomarkers by stimulating acupuncture point GB34 (Yangneungcheon) which has neuroprotective effect on the mouse model of Parkinson's disease, analysis of cDNA microarray on mRNAs of the substantia nigra was performed. METHODS:Male C57BL/6 mice were divided into two groups: 1-methyl-4-phenyl-1,2,...

journal_title：Neurological research

authors： Hong MS,Park HK,Yang JS,Park HJ,Kim ST,Kim SN,Park JY,Song JY,Park HK,Jo DJ,Park SW,HwanYun D,Ban JY,Chung JH

更新日期：2010-02-01 00:00:00

abstract：:This study was designed to evaluate the effects of two consecutive ischaemias on extracellular monoaminergic neurotransmitter concentrations. The data on the neuroamine changes induced by the second ischaemia could be used to assess the delay in aminergic neurotransmission subsequent to the primary injury. Dopamine (D...

journal_title：Neurological research

authors： Decombe R,Bentué-Ferrer D,Allain H,Van den Driessche J

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Diffusion-weighted imaging (DWI) abnormalities can frequently be detected after carotid endarterectomy (CEA) and carotid angioplasty with stent placement (CAS) of the carotid arteries. We looked for possible predictors for the development of DWI lesions during the intervention. METHODS:We investigated 41 pa...

journal_title：Neurological research

authors： Poppert H,Wolf O,Theiss W,Heider P,Hollweck R,Roettinger M,Sander D

更新日期：2006-07-01 00:00:00

abstract：:Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...

journal_title：Neurological research

authors： Droste DW,Sonne M,Siemens HJ,Kaps M

更新日期：1996-10-01 00:00:00

abstract：:Two hundred and sixty-one neurologically asymptomatic patients were examined by computed tomography (CT) following a variable number of transient ischaemic attacks (TIAs) experienced over different time intervals. Cerebral infarcts were discovered in 101 patients. Dominant hemisphere infarcts were usually small, of re...

journal_title：Neurological research

authors： Turnbull IW,Bannister CM

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:Elevated homocysteine level is a risk factor for ischemic stroke and associated with small vessel disease such as confluent leukoaraiosis in white and black population. We investigated the relationship between the total serum homocysteine level and ischemic stroke subtypes in Chinese population. METHODS:Thre...

journal_title：Neurological research

authors： Ma Y,Zhao X,Zhang W,Liu L,Wang Y,Fang R,Wang Y

更新日期：2010-07-01 00:00:00

abstract：:We elected to compare the clinical outcomes of carotid endarterectomy (CEA) patients who were thought to be at increased risk for peri-operative complications because of advanced age (> 79 years), medical comorbidities and contralateral internal carotid artery occlusion to patients without these risk factors. A prospe...

journal_title：Neurological research

authors： Harbaugh RE,Magnadottir HB

更新日期：2002-01-01 00:00:00

abstract：:To investigate the migration of neural stem cells as well as neural plastic changes in epileptic brain, spaciotemporal expression of immunoreactive highly polysialylated neural cell adhesion molecule (PSA-NCAM) was examined in amygdala kindling development of rat. The neural migration and synaptic remodeling detected ...

journal_title：Neurological research

authors： Sato K,Iwai M,Nagano I,Shoji M,Abe K

更新日期：2003-01-01 00:00:00

abstract：:Severe head injuries tend to be associated with hypermetabolism and hypercatabolism resulting in negative nitrogen balances which may exceed 30 grams day-1. Enteral feeding should begin as soon as the patient is hemodynamically stable, attempting to reach a non-protein caloric intake of at least 30-35 kcal kg-1 day-1 ...

journal_title：Neurological research

authors： Wilson RF,Dente C,Tyburski JG

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To establish a detailed technical procedure for studying the anatomical correlates of chronic cerebrospinal venous insufficiency in cadavers of multiple sclerosis and control subjects, and to present our findings of the normal anatomic venous structures, with reference to previous descriptions from the liter...

journal_title：Neurological research

authors： Diaconu CI,Staugaitis SM,Fox RJ,Rae-Grant A,Schwanger C,McBride JM

更新日期：2012-10-01 00:00:00

abstract：:Traumatic brain injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. Specific topics addressed in this paper include magnitude of the problem, causes, context of injury occurrence, risk factors, severity, outcome and impact of TBIs on...

journal_title：Neurological research

authors： Gururaj G

更新日期：2002-01-01 00:00:00

abstract：:Although rat models implanted with C6 glioma cells have been widely utilized for the assessment of new therapeutic modalities, a convenient in vivo model is still required. We implanted C6 glioma cells into the brains and the abdominal subcutaneous regions of Wistar rats, and evaluated the volumes of the growing tumor...

journal_title：Neurological research

authors： Watanabe K,Sakamoto M,Somiya M,Amin MR,Kamitani H,Watanabe T

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:In conditions with reduced glucose levels/inability of glucose utilization, ketone bodies, especially beta-hydroxybutyrate (BHB), become a major energy source in the brain. In animal models, BHB infusion shows acute beneficial effects on the hypoxic brain. The present prospective observational study is the f...

journal_title：Neurological research

authors： Pikija S,Trkulja V,Simundic AM,Vrcek E,Boskovic K,Bacani S

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:To investigate the prevalence of Parkinson's disease (PD), a three-phase study was conducted. METHODS:In phase 1, standardized interviews were performed in a random sample of elderly aged 65 years or older using a questionnaire. In phase 2, neurological examinations were performed to clinically diagnose P...

journal_title：Neurological research

authors： Kim JM,Kim JS,Kim KW,Lee SB,Park JH,Lee JJ,Kim YK,Kim SE,Jeon BS

更新日期：2010-10-01 00:00:00