Epidemiology of traumatic brain injuries: Indian scenario.

Abstract:

:Traumatic brain injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. Specific topics addressed in this paper include magnitude of the problem, causes, context of injury occurrence, risk factors, severity, outcome and impact of TBIs on rapidly transforming societies. It is estimated that nearly 1.5 to 2 million persons are injured and 1 million succumb to death every year in India. Road traffic injuries are the leading cause (60%) of TBIs followed by falls (20%-25%) and violence (10%). Alcohol involvement is known to be present among 15%-20% of TBIs at the time of injury. The rehabilitation needs of brain injured persons are significantly high and increasing from year to year. India and other developing countries face the major challenges of prevention, pre-hospital care and rehabilitation in their rapidly changing environments to reduce the burden of TBIs.

journal_name

Neurol Res

journal_title

Neurological research

authors

Gururaj G

doi

10.1179/016164102101199503

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

24-8

issue

1

eissn

0161-6412

issn

1743-1328

journal_volume

24

pub_type

杂志文章,评审
  • Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.

    abstract::Cerebral vasospasm and/or delayed ischaemic state following subarachnoid haemorrhage still remain unsolved serious problems. With the development and introduction of calcium antagonists as well as the advances in perioperative management, however, the clinical outcome has much improved in recent years. Among such drug...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1080/01616412.1993.11740140

    authors: Hongo K,Kobayashi S

    更新日期:1993-08-01 00:00:00

  • Increased hippocampal CD38 and systemic inflammation after partial hepatectomy does not induce impairment of spatial cognition.

    abstract:OBJECTIVE:The role of inflammation in cognitive alterations in a post-operative setting is still not fully understood. Surgical interventions can cause systemic inflammations which eventually can induce neuroinflammation. However, the main causes of functional changes after surgery are still elusive. In this study, we ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2016.1242452

    authors: Schnitzler S,Kopitz J,Plaschke K

    更新日期:2016-11-01 00:00:00

  • Stent, balloon-assisted coiling and double microcatheter for treating wide-neck aneurysms in anterior cerebral circulation.

    abstract:OBJECTIVE:To investigate the clinical application of adjuvant coiling techniques in treating anterior-circulation wide-necked aneurysms. METHODS:Over 4·5 years, 93 anterior-circulation wide-neck aneurysms in 81 patients were treated with different endovascular techniques: balloon-assisted, stent-assisted, and double-m...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132813Y.0000000234

    authors: Pan J,Xiao F,Szeder V,Yan M,Fan W,Gu J,He L,Zhan R

    更新日期:2013-12-01 00:00:00

  • Can safe and radical resection of all types of parasagittal meningiomas be achievable? -the introduction of a simplified surgical strategy.

    abstract::Background: Surgery of parasagittal meningiomas (PSMs) is still technically challenging, for the balance between radical resection and preservation of venous circulation. In this article, we'd systemically introduce the technical nuances of a simplified strategy for radical resection of all types of PSMs. All the case...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2020.1847530

    authors: Zhang N,Yang T,Hameed F,Zhang X,Yao Y,Li D,Li C,Yu S,Xu Y,Xia C,Fu X

    更新日期:2020-11-11 00:00:00

  • Comparison of transcranial Doppler ultrasonography and positron emission tomography using a three-dimensional template of the middle cerebral artery.

    abstract:OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313208X325191

    authors: Rijbroek A,Boellaard R,Vriens EM,Lammertsma AA,Rauwerda JA

    更新日期:2009-02-01 00:00:00

  • Association of glutathione S-transferases M1, P1 and T1 variations and risk of late-onset Alzheimer's disease.

    abstract:OBJECTIVE:Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) polymorphisms with the risk factors for AD have not been definitely confirmed. We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2017.1390902

    authors: Jafarian Z,Saliminejad K,Kamali K,Ohadi M,Kowsari A,Nasehi L,Khorram Khorshid HR

    更新日期:2018-01-01 00:00:00

  • Comprehensive management of arteriovenous malformations.

    abstract::The treatment of arteriovenous malformations depends on the efforts of a multidisciplinary team whose ultimate goal is to achieve better results when compared to the natural history of the pathology. The role of adjuvant treatment modalities such as radiosurgery and endovascular embolization is discussed. Treatment st...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1080/01616412.1998.11740583

    authors: de Oliveira E,Tedeschi H,Raso J

    更新日期:1998-12-01 00:00:00

  • Acute vasoparalysis after subarachnoid haemorrhage and cerebral trauma: general reflex phenomenon?

    abstract::In patients with head trauma and consecutive acute diffuse cerebral swelling the sudden initial rise in intracranial pressure with subsequent impairment of cerebral blood flow is explained by engorgement due to vasoparalysis. How quickly hyperaemic brain swelling can occur is shown by a case report. The review of clin...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1994.11740190

    authors: Krasznai L,Grote EH

    更新日期:1994-02-01 00:00:00

  • Endovascular treatment of giant and large intracranial aneurysms using the neuroform stent-assisted coil placement.

    abstract:BACKGROUND:Giant and large intracranial aneurysms represent enormous therapeutic challenges for neurosurgeons as well as for endovascular therapists. Since they may involve entire vessels or be irregular in shape, the rate of complete obliteration with GDCs is low and the incidence of recanalization is very high. So th...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章

    doi:10.1179/174313208X319017

    authors: Yang X,Wu Z,Mu S,Li Y,Lv M

    更新日期:2008-07-01 00:00:00

  • Progesterone treatment in rats after severe global cerebral ischemia promotes hippocampal dentate gyrus neurogenesis and functional recovery.

    abstract:OBJECTIVE:Rats treated with progesterone (P4) after ischemia show an adequate functional performance despite a significant loss of hippocampal pyramidal neurons, suggesting that P4 could favour a permissive microenvironment for cerebral plasticity mechanisms. The possibility of P4 treatment promoting the survival of ne...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2019.1576356

    authors: Montes P,Vigueras-Villaseñor RM,Rojas-Castañeda JC,Monfil T,Cervantes M,Moralí G

    更新日期:2019-05-01 00:00:00

  • Alzheimer's disease like pathology induced six weeks after aggregated amyloid-beta injection in rats: increased oxidative stress and impaired long-term memory with anxiety-like behavior.

    abstract:OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2016.1209337

    authors: Sharma S,Verma S,Kapoor M,Saini A,Nehru B

    更新日期:2016-09-01 00:00:00

  • Endovascular treatment of congenital carotid-cavernous fistulas in infancy.

    abstract::Congenital dural arteriovenous fistulas have been infrequently described in pediatric population and they generally affect the transverse, sigmoid, straight or sagittal sinuses. Congenital carotid-cavernous fistulas in infancy are considered very rare and to our knowledge, only four cases have been reported in literat...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313208X291612

    authors: Cohen JE,Gomori JM,Grigoriadis S,Rajz G

    更新日期:2008-07-01 00:00:00

  • Experimental brain ischaemia: assessment of injury by magnetic resonance spectroscopy and histology.

    abstract::Phosphorus magnetic resonance spectroscopy (31P-MRS) was made to measure changes in brain high energy phosphate compounds, adenosine triphosphate (ATP) and phosphocreatine (PCr), inorganic phosphorus (Pi) and intracellular pH (pHi) during a prolonged period of incomplete brain ischaemia produced, in anaesthetized dogs...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1990.11739943

    authors: Anderson ML,Smith DS,Nioka S,Subramanian H,Garcia JH,Halsey JH,Chance B

    更新日期:1990-12-01 00:00:00

  • Interleukin-21 expression in hippocampal astrocytes is enhanced following kainic acid-induced seizures.

    abstract:OBJECTIVE:Interleukin-21 (IL-21) is a cytokine that is an important modulator of immune responses. However, its roles in epilepsy are not completely clear. Here, we investigated the expression and distribution of IL-21 in a kainic acid (KA)-induced acute seizure mouse model. MATERIALS AND METHODS:Mice (n = 146) were r...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2015.1135557

    authors: Xiong XY,Wang TG,Yang MH,Meng ZY,Yang QW,Wang FX

    更新日期:2016-02-01 00:00:00

  • Treadmill exercise is associated with reduction of reactive microgliosis and pro-inflammatory cytokine levels in the hippocampus of type 2 diabetic rats.

    abstract:OBJECTIVES:In the present study, we investigated the effects of treadmill exercise on microglial activation and the subsequent release of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6 and IL-1-beta in the hippocampus in a rat model of type 2 diabetes. METHODS:At 30 weeks of age, diabetic (Zucker diabeti...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132815Y.0000000015

    authors: Yoo DY,Chae J,Jung HY,Yim HS,Kim JW,Nam SM,Kim DW,Choi JH,Seong JK,Yoon YS,Hwang IK

    更新日期:2015-08-01 00:00:00

  • Dynamical levels of plasma F(1+2) and D-dimer in patients with acute cerebral infarction during intravenous urokinase thrombolysis.

    abstract:OBJECTIVE:To explore the value of dynamically monitored levels of plasma prothrombin fragment(1+2) (F(1+2)) and D-dimer in the process of thrombolysis with urokinase. METHODS:Blood samples were collected at baseline and at hours 1, 2, 3, 6, 12, 24, 48, 72, and 96 after urokinase infusion finished. The levels of plasma...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X443991

    authors: Meng R,Ji X,Li B,Zhou J,Li W,Ding Y

    更新日期:2009-05-01 00:00:00

  • Cerebellar contusion associated with type I Chiari malformation following supratentorial head trauma: case report.

    abstract::Acute presentation of Type I Chiari malformation in children is distinctly rare. An 11 year old male suffered a trauma to the right temporal-parietal region in a tobogganing accident resulting in an open depressed skull fracture. Radiographic evaluation included a Computed Tomographic scan which also demonstrated a si...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1998.11740599

    authors: Couldwell WT,Zhang W,Allen R,Arce D,Stillerman CB

    更新日期:1998-01-01 00:00:00

  • Vasoconstrictor mechanism of neuropeptides augmented after endothelial removal in isolated, perfused canine basilar arteries.

    abstract::In order to investigate the functional role of endothelium and vasoeffector mechanism in cerebrovascular responses to neuropeptides, the stainless steel cannula inserting method was applied to examine the responses to intraluminally-applied bradykinin, substance P and vasopressin in isolated and perfused canine basila...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1995.11758611

    authors: Tsuji T,Cook DA

    更新日期:1995-06-01 00:00:00

  • Superior protective effects of phenytoin against hypoxia in a pharmacological screening test.

    abstract::The selection of drugs to prevent the development of pathology in cerebral infarction remains an important problem. For the selection of effective drugs from among a large number of possible candidates, widely-used test screening techniques are sufficient for obtaining a good understanding of candidate drug effects. T...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1988.11739810

    authors: Imaizumi S,Suzuki J,Kinouchi H,Yoshimoto T

    更新日期:1988-03-01 00:00:00

  • Cerebral edema leading to decompressive craniectomy: an assessment of the preceding clinical and neuromonitoring trends.

    abstract::The aim of this study was to examine the pre-operative clinical and neuromonitoring courses in patients with a decompressive craniectomy to assess and to compare clinical and neuromonitoring signs indicating extensive cerebral edema. We conducted a retrospective analysis of the clinical signs and courses of simultaneo...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164103101201742

    authors: Strege RJ,Lang EW,Stark AM,Scheffner H,Fritsch MJ,Barth H,Mehdorn HM

    更新日期:2003-07-01 00:00:00

  • Role of the endothelium on extraluminal and intraluminal vasoactive mechanisms in the perfused rabbit basilar artery.

    abstract::In order to investigate the role of the endothelium in the regulation of cerebrovascular tone, we studied selective intraluminal and extraluminal vasoactive mechanisms of acetylcholine, potassium and serotonin. We also examined the effects of removal of the endothelium on these vasoactive responses. With 0.75 g of ten...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1993.11740128

    authors: Ogawa R,Ohta T,Tsuji M,Mori M

    更新日期:1993-06-01 00:00:00

  • Hourly neurologic assessments for traumatic brain injury in the ICU.

    abstract:OBJECTIVES:Hourly neurologic assessments for traumatic brain injury (TBI) in the critical care setting are common practice but prolonged use may actually be harming patients through sleep deprivation. We reviewed practice patterns at our institution in order to gain insight into the role of frequent neurological assess...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132813Y.0000000285

    authors: Stone JJ,Childs S,Smith LE,Battin M,Papadakos PJ,Huang JH

    更新日期:2014-02-01 00:00:00

  • One year of home-based daily FES in complete lower motor neuron paraplegia: recovery of tetanic contractility drives the structural improvements of denervated muscle.

    abstract:OBJECTIVE:Spinal cord injury (SCI) causes muscle atrophy, which is particularly severe, due to inability to perform tetanic contractions, when lower motor neurons (LMN) are involved. We performed a longitudinal study in 25 Europeans suffering from complete conus cauda syndrome from 0.7 to 8.7 years comparing functional...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X385644

    authors: Kern H,Carraro U,Adami N,Hofer C,Loefler S,Vogelauer M,Mayr W,Rupp R,Zampieri S

    更新日期:2010-02-01 00:00:00

  • Catalpol protects rat pheochromocytoma cells against oxygen and glucose deprivation-induced injury.

    abstract:OBJECTIVES:Catalpol has been identified to have neuroprotective effect on gerbils subjected to transient global cerebral ischemia. However, the mechanism that catalpol prevents ischemia is still unclear. In the present study, PC12 cells, exposed to oxygen and glucose deprivation (OGD) followed by reperfusion, were used...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164107X229894

    authors: Wang Z,An LJ,Duan YL,Li YC,Jiang B

    更新日期:2008-02-01 00:00:00

  • Silent cerebral ischemic lesions after carotid artery stenting with distal cerebral protection.

    abstract:OBJECTIVE:To evaluate by MR diffusion weighted image (DWI-MR) the presence of new ischemic cerebral lesions after carotid artery stenting (CAS) and distal cerebral protection, in patients with internal carotid artery (ICA) stenosis >70. METHODS:Sixty-seven CAS were performed under cerebral protection with a distal fil...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164105X35431

    authors: González A,Piñero P,Martínez E,González-Marcos JR,Rafel E,Mayol A,Gil-Peralta A

    更新日期:2005-01-01 00:00:00

  • Habenular neuron responses to noxious input are modified by dorsal raphe stimulation.

    abstract::Single-cell experiments were undertaken to characterize the neurons of the rat habenular complex (Hab) which respond to noxious input and the extent to which the noxious responses can be modulated by dorsal raphe stimulation. The reported observations demonstrate that habenular neurons exhibit two response patterns to...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1990.11739929

    authors: Dafny N,Qiao JT

    更新日期:1990-06-01 00:00:00

  • Cardiac risk factors and potential treatments in Alzheimer's disease.

    abstract::Dementia is one of the commonest neurological disorders in the elderly population. In regards to the increasing longevity of populations worldwide, prevention of dementia has become a major public health challenge. There has been an intense research in the identification of modifiable risk factors for dementia. These ...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/016164106X130498

    authors: Bergmann C,Sano M

    更新日期:2006-09-01 00:00:00

  • Increased risk of post-stroke epilepsy in Chinese patients with a TRPM6 polymorphism.

    abstract:OBJECTIVES:We attempted to determine whether a functional polymorphism of TRPM6 (rs2274924) is associated with susceptibility to epilepsy following ischemic stroke, and to further explore the effect of this polymorphism on serum levels of Mg2+ in post-stroke patients. METHODS:We carried out a case-control study on 378...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2019.1568755

    authors: Fu CY,Chen SJ,Cai NH,Liu ZH,Zhang M,Wang PC,Zhao JN

    更新日期:2019-04-01 00:00:00

  • Topical application of the hematostatic agent Surgiflo® could attenuate brain injury in experimental TBI mice.

    abstract:OBJECT:The pathologies resulting from traumatic brain injury (TBI) have been thoroughly studied, but rarely have the effects of bleeding and coagulation in the early stage of TBI been considered. In this study, we investigated the effects of topical Surgiflo® application on brain injury in experimental TBI mice using S...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2017.1330815

    authors: Guo D,Li D,Li J,Li Y,Hu X,Guan F,Yang B

    更新日期:2017-09-01 00:00:00

  • Computer-controlled acupuncture. Quantification and separation of specific effects.

    abstract::The effects of acupuncture have been described and handed down empirically for centuries but there are few reports based on objective data. The aim of this study was to provide selective evidence of a specific effect of acupuncture on the brain and the eye using a Doppler ultrasound technique. A transcranial Doppler s...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章

    doi:10.1080/01616412.1999.11740970

    authors: Litscher G,Wang L,Yang NH,Schwarz G

    更新日期:1999-09-01 00:00:00