Increased hippocampal CD38 and systemic inflammation after partial hepatectomy does not induce impairment of spatial cognition.

abstract：OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, characterized by a selective progressive degeneration of the motor system. Electromyography is essential for the diagnosis of ALS. The measurement of motor conduction of peripheral nerves is of major importance to recognize other poss...

journal_title：Neurological research

authors： Mohammadi B,Krampfl K,Kollewe K,Seyfadini A,Bufler J,Dengler R

更新日期：2007-07-01 00:00:00

abstract：:This study was designed to assess the effects of volume expansion with Fluosol-DA and hetastarch on local cerebral blood flow (CBF), cortical O2 availability (O2a) and computerized EEG power data during cerebral ischaemia in a primate stroke model. Focal cerebral ischaemia was produced in 20 anaesthetized Macaca monke...

journal_title：Neurological research

authors： Tranmer BI,Iacobacci R,Feiler S

更新日期：1990-03-01 00:00:00

abstract：:Mountain trekking is significantly increasing in popularity. Hypoxia seems to play a key role in the pathogenesis of acute mountain sickness (AMS). The purpose of this study was to investigate regional cerebral (rSO2) and peripheral (SaO2) oxygen saturation for the first time, during 22 days high altitude trekking (me...

journal_title：Neurological research

authors： Hadolt I,Litscher G

更新日期：2003-03-01 00:00:00

abstract：:Vestibular neuritis (VN) rapidly damages unilateral vestibular periphery, inducing severe balance disorders. In most cases, such vestibular imbalance is gradually restored to within the normal level after clinical therapies. This successive clinical recovery occurs due to regeneration of vestibular periphery and/or ac...

journal_title：Neurological research

authors： Kitahara T,Kondoh K,Morihana T,Okumura S,Horii A,Takeda N,Kubo T

更新日期：2003-04-01 00:00:00

abstract：:The frequency of skull metastasis from hepatocellular carcinoma (HCC) is increasing together with the recent progress in the management of the primary lesion. Cases are often complicated with poor general conditions or metastasis to the other organs, and not readily indicated for surgery. A direct injection of ethanol...

journal_title：Neurological research

authors： Isaka T,Yoshimine T,Fujimoto K,Masuzawa M,Maruno M,Hayakawa T,Nakatani S

更新日期：1998-12-01 00:00:00

abstract：:Cyclic GMP (cGMP) mediates smooth muscle relaxation in the central nervous system. In subarachnoid hemorrhage (SAH), decreases in intrinsic nitric oxide (NO) cause cerebral vasospasms due to the regulation of cGMP formation by NO-mediated pathways. As phosphodiesterase type V (PDE V) selectively hydrolyzes cGMP, we hy...

journal_title：Neurological research

authors： Inoha S,Inamura T,Ikezaki K,Nakamizo A,Amano T,Fukui M

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:This study investigated the relationship between traumatic coagulopathy and severe brain swelling (SBS) during decompressive surgery to evacuate a supratentorial intradural mass lesion in patients with traumatic brain injury (TBI). METHODS:A retrospective study was conducted in 96 patients who consecutively ...

journal_title：Neurological research

authors： Wang K,Xue Y,Chen X,Zhou B,Lou M

更新日期：2013-07-01 00:00:00

abstract：:Recent evidence indicates that different vascular risk factors are present in Alzheimer's disease (AD) and other prevalent dementia types probably contributing to deterioration of cerebrovascular function, thus enhancing neurodegeneration and premature neuronal death due to a reduction in brain perfusion. Brain blood ...

journal_title：Neurological research

authors： Cacabelos R,Fernández-Novoa L,Lombardi V,Corzo L,Pichel V,Kubota Y

更新日期：2003-09-01 00:00:00

abstract：:The objective of this study was to investigate the effects of transplanted bone marrow mesenchymal stem cells (BMSCs) administered via internal jugular vein injection, carotid artery injection, or intraventricular transplantation for the treatment of cerebral infarction, which was modeled in rats. The neurological sco...

journal_title：Neurological research

authors： Ruan GP,Han YB,Wang TH,Xing ZG,Zhu XB,Yao X,Ruan GH,Wang JX,Pang RQ,Cai XM,He J,Zhao J,Pan XH

更新日期：2013-03-01 00:00:00

abstract：:Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...

journal_title：Neurological research

authors： Shen M,Zheng Y,Zhu K,Cai Z,Liu W,Sun X,Liu J,Zhu D

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20 in mice. METHODS:Mi...

journal_title：Neurological research

authors： Figueredo YN,Rodríguez EO,Reyes YV,Domínguez CC,Parra AL,Sánchez JR,Hernández RD,Verdecia MP,Pardo Andreu GL

更新日期：2013-10-01 00:00:00

abstract：:In patients with head trauma and consecutive acute diffuse cerebral swelling the sudden initial rise in intracranial pressure with subsequent impairment of cerebral blood flow is explained by engorgement due to vasoparalysis. How quickly hyperaemic brain swelling can occur is shown by a case report. The review of clin...

journal_title：Neurological research

authors： Krasznai L,Grote EH

更新日期：1994-02-01 00:00:00

abstract：:An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...

journal_title：Neurological research

authors： Sano K

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To determine the functional abnormalities of the Leu89Pro mutation in connexin32 (CX32), which we have previously reported is present within an X-linked dominant Charcot-Marie-Tooth disease family. In this family, male patients were moderately to severely affected. METHODS:We performed immunofluorescence to ...

journal_title：Neurological research

authors： Da Y,Wang W,Liu Z,Chen H,Di L,Previch L,Chen Z

更新日期：2016-10-01 00:00:00

abstract：:Induction of stress proteins is thought to be important in the protection of cells from a variety of environmental insults including heat, hypoxia and ischemia. The aim of this study was to compare the mechanism of induction of heat shock protein 72 (HSP72) in primary cultures of murine cortical astrocytes by heat and...

journal_title：Neurological research

authors： Bergeron M,Mivechi NF,Giaccia AJ,Giffard RG

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:Surgical management of tumors in the sacropelvic region is a challenging field of spine surgery because of the region's complex local anatomy and biomechanics. Recent developments in anesthesia and intensive care have allowed us to perform extended surgeries focused on the en bloc resection of sacropelvic tu...

journal_title：Neurological research

authors： Varga PP,Szoverfi Z,Lazary A

更新日期：2014-06-01 00:00:00

abstract：:Different surgical approaches exist for the treatment of chronic subdural hematoma. None of these approaches is superior to the other, so a minimal-invasive device (a hollow screw) was developed. The system consists of a stable hollow screw of surgical steel with a perforated tip, a hand-drill, screwdriver with guide,...

journal_title：Neurological research

authors： Emonds N,Hassler WE

更新日期：1999-01-01 00:00:00

abstract：:The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...

journal_title：Neurological research

authors： Matsui T,Nagafuji T,Mori T,Asano T

更新日期：1997-04-01 00:00:00

abstract：:Previous work has shown that unsaturated fatty acid components of model membrane phospholipids in vitro, damaged via a free radical mechanism, are protected by the presence of cholesterol in these membranes. The participation of these membrane lipids in the pathogenesis of traumatic injury to brain was studied in vivo...

journal_title：Neurological research

authors： Mitamura JA,Seligman ML,Solomon JJ,Flamm ES,Demopoulos HB,Ransohoff J

更新日期：1981-01-01 00:00:00

abstract：:In order to investigate the role of the endothelium in the regulation of cerebrovascular tone, we studied selective intraluminal and extraluminal vasoactive mechanisms of acetylcholine, potassium and serotonin. We also examined the effects of removal of the endothelium on these vasoactive responses. With 0.75 g of ten...

journal_title：Neurological research

authors： Ogawa R,Ohta T,Tsuji M,Mori M

更新日期：1993-06-01 00:00:00

abstract：:The aim of this study was to use quantitative microdialysis to estimate the true extracellular concentrations of glucose and lactate in minimally disturbed human brain. These values are important as criteria for microdialytical monitoring in critical care patients and for determining therapy. Microdialysis procedures ...

journal_title：Neurological research

authors： Langemann H,Alessandri B,Mendelowitsch A,Feuerstein T,Landolt H,Gratzl O

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:This study examined whether a needle-free acupuncture can be an alternative to conventional needle injection acupuncture. METHODS:Patients (n=101) suffering myofascial shoulder pain were randomly assigned to either needle-free or conventional needle injection acupuncture group. Bee venom was administered int...

journal_title：Neurological research

authors： An K,Kim YS,Kim HY,Lee H,Hahm DH,Lee KS,Kang SK

更新日期：2010-02-01 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy (31P-MRS) was made to measure changes in brain high energy phosphate compounds, adenosine triphosphate (ATP) and phosphocreatine (PCr), inorganic phosphorus (Pi) and intracellular pH (pHi) during a prolonged period of incomplete brain ischaemia produced, in anaesthetized dogs...

journal_title：Neurological research

authors： Anderson ML,Smith DS,Nioka S,Subramanian H,Garcia JH,Halsey JH,Chance B

更新日期：1990-12-01 00:00:00

abstract：:The objective was to examine the effect of the nitric oxide synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME) on leukocyte adhesion in the cerebral microcirculation during reperfusion following partial forebrain ischemia in the rat. Intravital fluorescence video-microscopy through a closed cranial win...

journal_title：Neurological research

authors： Hudetz AG,Wood JD,Kampine JP

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:Vascular endothelial growth factor is a potent stimulator of angiogenesis; activation of hypoxia inducible factor-1alpha and p44/42 mitogen-activated protein kinase pathways has been associated with vascular endothelial growth factor production. The present study examined if thrombin modulates vascular endoth...

journal_title：Neurological research

authors： Xu Y,Gu Y,Keep RF,Heth J,Muraszko KM,Xi G,Hua Y

更新日期：2009-09-01 00:00:00

abstract：:Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...

journal_title：Neurological research

authors： Nagasawa S,Kawanishi M,Tanaka H,Ohta T,Nagayasu S,Kikuchi H

更新日期：1993-12-01 00:00:00

abstract：:Because clinicians require objectively demonstrable neurological deficits to confirm a diagnosis, the recognition of embolic events in the nervous system is generally restricted to the effects of ischemic necrosis produced by arterial occlusion. However, magnetic resonance imaging (MRI) has shown that lesser degrees o...

journal_title：Neurological research

authors： James PB

更新日期：2007-03-01 00:00:00

abstract：:The purpose of this study was to determine the efficacy of nicardipine prolonged-release implants for preventing vasospasm in a canine SAH model in a dose-escalating placebo-controlled blind fashion. Drug-release kinetics of copoly(lactic/glycolic acid) pellet containing nicardipine were evaluated in vitro. In vivo, 1...

journal_title：Neurological research

authors： Kawashima A,Kasuya H,Sasahara A,Miyajima M,Izawa M,Hori T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:Papaverine has been used in treating vasospasm following subarachnoid hemorrhage (SAH). However, its action mechanism for cerebral vascular relaxation is not clear. Potassium and calcium channels are closely related to the contraction and relaxation of cerebral smooth muscle. Therefore, to identify the role ...

journal_title：Neurological research

authors： Han DH,Bai GY,Yang TK,Sim BS,Kwak YG,Kim CJ

更新日期：2007-09-01 00:00:00

abstract：:As early as 1 to 3 hr after cord transection, proliferation of many reactive oligodendrocytes was observed. Bundles of microfilaments and microtubules were observed in those cells that sent out long, complex pseudopodlike processes near the area of injury. These reactive oligodendrocytes may be comparable to Vaughn's ...

journal_title：Neurological research

authors： Chang LW,Kao CC

更新日期：1980-01-01 00:00:00