Hydrogen gas protects against delayed encephalopathy after acute carbon monoxide poisoning in a rat model.

abstract：OBJECTIVE:Cerebral small vessel disease (CSVD) describes a syndrome of neuroimaging, pathological, and associated clinical features caused by small intracranial vascular lesions, which commonly coexists with large artery atherosclerosis (LAA) and has been identified as a major cause of motor impairment over time. In th...

journal_title：Neurological research

authors： Zhu H,Li Z,Lv J,Zhao R

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:This study investigated the role of matrix metalloproteinase-9 (MMP-9) in early brain injury after subarachnoid hemorrhage (SAH). METHOD:Sprague-Dawley male rats (n=36) weighing between 250 and 300 g were used. SAH was produced by injecting autologous arterial blood into the pre-chiasmatic cistern. MMP-9 pro...

journal_title：Neurological research

authors： Guo Z,Sun X,He Z,Jiang Y,Zhang X,Zhang JH

更新日期：2010-09-01 00:00:00

abstract：:The purpose of this prospective observational study was to investigate the relation between the frequency of critical neuromonitoring parameters (brain tissue pO2, (PtiO2) < or = 10 mmHg, intracranial pressure (ICP) > 20 mmHg, cerebral perfusion pressure (CPP) < or = 70 mmHg) and outcome after severe aneurysmal subara...

journal_title：Neurological research

authors： Meixensberger J,Vath A,Jaeger M,Kunze E,Dings J,Roosen K

更新日期：2003-07-01 00:00:00

abstract：:Anoxic depolarization (AD) is one of the major physiological characteristics in the ischemic core. The effect of mild hypothermia on the appearance of AD and subsequent brain injury following profound ischemia is studied to evaluate the protective mechanism of hypothermia against severe ischemia. Sprague-Dawley rats w...

journal_title：Neurological research

authors： Kaminogo M,Ichikura A,Onizuka M,Takahata H,Matsuo Y,Kitagawa N,Shibata S

更新日期：1999-10-01 00:00:00

abstract：:We examined the microsurgical anatomy of the supratentorial subarachnoid cisterns with a surgical microscope in 20 brains prepared using the immersion technique. The adult brains were immersed in Ringer's solution and air was injected into the subarachnoid cisterns while the brains remained submerged in solution. We i...

journal_title：Neurological research

authors： Vinas FC,Fandino R,Dujovny M,Chavez V

更新日期：1994-12-01 00:00:00

abstract：:Before extending the application of motor cortex stimulation it is important to investigate the intimate mechanisms by which it alleviates intractable pain and to consider possible side effects. Self-mutilation in animals following extensive neurectomy or posterior rhizotomy of a limb is thought to reveal severe dyses...

journal_title：Neurological research

authors： Pioli EY,Gross CE,Meissner W,Bioulac BH,Bezard E

更新日期：2003-03-01 00:00:00

abstract：:Using magnetic resonance imaging, we reviewed 141 infratentorial infarcts in 81 consecutive cases: 65 infarcts were seen in the paramedian pons, while 18 in the posterior inferior cerebellar artery (PICA) territory and 17 in the watershed area between PICA and superior cerebellar artery. No comparable sign or symptom ...

journal_title：Neurological research

authors： Yin WM,Nagata K,Satoh Y,Yokoyama E,Watahiki Y,Yuya H,Hirata Y,Ogawa T,Inugami A

更新日期：1994-06-01 00:00:00

abstract：:Following cerebral ischemia, the extracellular concentration of excitatory amino acids increases, and the excitatory cell death may play an important role contributing to ischemic neuronal damage. Although sequential metabolic changes in permanent local cerebral ischemia have been reported, the effect of reperfusion i...

journal_title：Neurological research

authors： Liu Y,Mituska S,Hashizume K,Hosaka T,Nukui H

更新日期：1996-12-01 00:00:00

abstract：:This investigation was designed to clarify the chronic effects of cardiogenic emboli on cerebral perfusion and tissue densities within remaining noninfarcted brain. Local cerebral perfusion and tissue densities were measured by xenon-contrasted CT scanning and compared by cross-sectional designs among normal volunteer...

journal_title：Neurological research

authors： Obara K,Meyer JS,Muramatsu K,Mortel KF

更新日期：1995-10-01 00:00:00

abstract：:The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...

journal_title：Neurological research

authors： Matsui T,Nagafuji T,Mori T,Asano T

更新日期：1997-04-01 00:00:00

abstract：:The STA-MCA (superficial temporal artery-middle cerebral artery) bypass has become increasingly popular in the treatment of cerebral vascular disease. Indication and assessment of postoperative results have been based on clinical grounds and on findings from cerebral angiography (10). In order to obtain objective data...

journal_title：Neurological research

authors： Gratzl O,Schmiedek P

更新日期：1983-01-01 00:00:00

abstract：:Objective: To determine the time of dementia diagnosis, symptom intensity and to assess the comorbidities.Methods: 110 patients with dementia or mild cognitive impairment were enrolled in this retrospective study. The study group was divided into subgroups: patients with a maximum of three (S ≤ 3 n = 62) and four or m...

journal_title：Neurological research

authors： Niedziela N,Nowak MM,Lis M,Blaszkowska M,Kośmider R,Adamczyk-Sowa M

更新日期：2020-05-01 00:00:00

abstract：:Parkinson's disease (PD) the second most common age-associated progressive neurodegenerative disorder is characterized by loss of dopaminergic neurons, cytoplasmic inclusions of aggregated proteins (Lewy bodies), and neuroinflammation. The inflammation of neurons causes release of various inflammatory mediators (IFNs,...

journal_title：Neurological research

authors： Pal R,Tiwari PC,Nath R,Pant KK

更新日期：2016-12-01 00:00:00

abstract：:We studied brain temperature and the effect of mild hypothermia in 58 patients after severe head injury (SHI). Brain tissue oxygen tension (ptiO2), carbon dioxide tension (ptiCO2), tissuie pH (pHti) and temperature (T.br) were measured using a multiparameter probe. Microdialysis was performed to measure glucose, lacta...

journal_title：Neurological research

authors： Soukup J,Zauner A,Doppenberg EM,Menzel M,Gilman C,Bullock R,Young HF

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:In multiple sclerosis (MS) demyelination occurs in both white and gray matter. Here we introduce an electrophysiological approach for studying functional demyelination and myelin repair in rat hippocampus, a gray matter structure, which is frequently affected in patients suffering from MS. METHODS:Using a s...

journal_title：Neurological research

authors： Azin M,Goudarzvand M,Mirnajafi-Zadeh J,Javan M

更新日期：2013-10-01 00:00:00

abstract：:One case of dural arteriovenous malformation in the base of the anterior cranial fossa is reported. It was discovered by means of a PW-Doppler examination of angular branch of the ophthalmic artery in a patient under observation for hypertrophy of a superficial temporal artery. The nidus was located in the region of t...

journal_title：Neurological research

authors： Fiori L,Parenti G,Puglioli M,Padolecchia R

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:The role of inflammation in cognitive alterations in a post-operative setting is still not fully understood. Surgical interventions can cause systemic inflammations which eventually can induce neuroinflammation. However, the main causes of functional changes after surgery are still elusive. In this study, we ...

journal_title：Neurological research

authors： Schnitzler S,Kopitz J,Plaschke K

更新日期：2016-11-01 00:00:00

abstract：OBJECT:The pathologies resulting from traumatic brain injury (TBI) have been thoroughly studied, but rarely have the effects of bleeding and coagulation in the early stage of TBI been considered. In this study, we investigated the effects of topical Surgiflo® application on brain injury in experimental TBI mice using S...

journal_title：Neurological research

authors： Guo D,Li D,Li J,Li Y,Hu X,Guan F,Yang B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to investigate the effect of bone mesenchymal stem cells (BMSCs) conditioned medium on BMP4-induced activation of the Smad signaling pathway during the process of neural stem cells differentiation. METHODS:We designed four experimental groups: (A) control group, (B) BMP-4 treatment g...

journal_title：Neurological research

authors： Fang H,Song P,Shen C,Liu X,Li H

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To review the use of immunoassays in the diagnosis and research of disorders affecting the nervous system. METHODS:Systematic review of the English literature. RESULTS:Immunoassays have demonstrated utility for: (1) the detection of antigen (molecules, genes, gene products, peptides, hormones and drug meta...

journal_title：Neurological research

authors： Meriggioli MN

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Elevated homocysteine level is a risk factor for ischemic stroke and associated with small vessel disease such as confluent leukoaraiosis in white and black population. We investigated the relationship between the total serum homocysteine level and ischemic stroke subtypes in Chinese population. METHODS:Thre...

journal_title：Neurological research

authors： Ma Y,Zhao X,Zhang W,Liu L,Wang Y,Fang R,Wang Y

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:Microglial cells in spinal dorsal horn can be activated by nociceptive stimuli and the activated microglial cells release various cytokines enhancing the nociceptive transmission. However, the mechanisms underlying the activation of spinal microglia during nociceptive stimuli have not been well understood. I...

journal_title：Neurological research

authors： Li L,Wu Y,Bai Z,Hu Y,Li W

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:The present study characterized glial cell injury provoked in adult rat chiasm within 24 hours after a single, high-dose irradiation of 20 Gy. METHODS:All chiasmal glial cells in a section were counted, and the percentage of TUNEL-positive glial cells exhibiting apoptotic morphology was defined as the apopt...

journal_title：Neurological research

authors： Nagayama K,Kurita H,Nakamura M,Kusuda J,Tonari A,Takayama M,Fujioka Y,Shiokawa Y

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:The amyloid hypothesis stimulates the discovery of compounds, which promotes beta-amyloid peptide (Aβ) clearance, thereby altering the underlying pathophysiology of Alzheimer's disease (AD). Hence, the present study aims at the evaluation of anti-amyloidogenic potential of Gelidiella acerosa. METHODS:Prevent...

journal_title：Neurological research

authors： Syad AN,Devi KP

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:We have investigated whether magnetic stimulation of the sural nerve can evoke a flexor reflex recorded from the ipsilateral short head of the biceps femoris muscle. METHODS:The sural nerve was subjected to magnetic stimulation as well as by single-pulse electrical stimulation in healthy subjects. RESULTS:...

journal_title：Neurological research

authors： Kizilay F,Bilgen R,Aydin Gungor H,Uysal H,Ertekin C

更新日期：2011-07-01 00:00:00

abstract：:Objective Preoperative magnetic resonance (MR) angiography sometimes shows the absence of collateral flow via the circle of Willis. This study examined whether brain temperature (BT) imaging on multi-voxel proton MR spectroscopy after this finding increases the accuracy of predicting hemispheric ischemia during intern...

journal_title：Neurological research

authors： Tsutsui S,Nanba T,Yoshioka Y,Sasaki M,Fujiwara S,Kobayashi M,Yoshida K,Miyoshi K,Sato S,Ogasawara K

更新日期：2018-08-01 00:00:00

abstract：:Objectives: Neurovascular compression syndromes (NVCS) could be cured with an intravascular device that releases compression of the root entry zone of cranial nerves by changing the course of offending vessels. The purpose of this study was to report our results of in vitro and in vivo experiments with a novel intra-a...

journal_title：Neurological research

authors： Chun Y,Chen Y,Elsisy M,Sukinik J,Shridhar P,Park JK,Kim YB,Hong CK,Chung J

更新日期：2019-07-01 00:00:00

abstract：:We describe a case of rebleeding from an intracranial vertebral dissecting aneurysm following proximal clipping. This case suggests that proximal clipping alone may not be an adequate surgical procedure to prevent rebleeding. Surgical treatment of intracranial dissecting aneurysms in the vertebral artery presenting as...

journal_title：Neurological research

authors： Kawamata T,Tanikawa T,Takeshita M,Onda H,Takakura K,Toyoda C

更新日期：1994-04-01 00:00:00

abstract：:The goal of this paper is to provide scientists with a comprehensive review of the state-of-the-art influence the ischemic blood-brain barrier (BBB) has on the final development of Alzheimer's disease and to provide detailed food-for-thought which will hopefully stimulate more researchers in this area of neuroscience....

journal_title：Neurological research

authors： Pluta R

更新日期：2006-09-01 00:00:00

abstract：:This study was designed to assess the effects of volume expansion with Fluosol-DA and hetastarch on local cerebral blood flow (CBF), cortical O2 availability (O2a) and computerized EEG power data during cerebral ischaemia in a primate stroke model. Focal cerebral ischaemia was produced in 20 anaesthetized Macaca monke...

journal_title：Neurological research

authors： Tranmer BI,Iacobacci R,Feiler S

更新日期：1990-03-01 00:00:00