Correlation between distal motor latency and compound muscle action potential in amyotrophic lateral sclerosis.

Abstract:

OBJECTIVES:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, characterized by a selective progressive degeneration of the motor system. Electromyography is essential for the diagnosis of ALS. The measurement of motor conduction of peripheral nerves is of major importance to recognize other possible causes of progressive muscle wasting. However, there are also pathologic changes in nerve conduction studies in ALS patients. METHODS:In this study we analysed the values of distal motor latency (DML), compound muscle action potential (CMAP) and motor nerve conduction velocity (MNCV) in 95 patients with definite ALS. RESULTS:We found slight slowing of MNCV and moderate to strong reduction of CMAP and a prolongation of DML. We found no significant correlation between MNCV and CMAP. DISCUSSION:The main finding of the present work was the negative correlation between DML and CMAP. It is interpreted as a very distal axonal damage as the main reason for prolongation of DML in ALS patients.

journal_name

Neurol Res

journal_title

Neurological research

authors

Mohammadi B,Krampfl K,Kollewe K,Seyfadini A,Bufler J,Dengler R

doi

10.1179/016164107X159261

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

425-8

issue

5

eissn

0161-6412

issn

1743-1328

journal_volume

29

pub_type

杂志文章
  • Superior protective effects of phenytoin against hypoxia in a pharmacological screening test.

    abstract::The selection of drugs to prevent the development of pathology in cerebral infarction remains an important problem. For the selection of effective drugs from among a large number of possible candidates, widely-used test screening techniques are sufficient for obtaining a good understanding of candidate drug effects. T...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1988.11739810

    authors: Imaizumi S,Suzuki J,Kinouchi H,Yoshimoto T

    更新日期:1988-03-01 00:00:00

  • Cerebral hemodynamics during induced tachycardia in routine electrophysiologic studies: a transcranial Doppler study.

    abstract::Supraventricular and ventricular tachyarrhythmia are established causes of syncope. We investigated the mean blood flow velocities (Vmean) of the middle cerebral arteries (MCA) during routine cardiac electrophysiologic studies in patients with supraventricular and ventricular tachyarrhythmias in order to evaluate the ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1998.11740555

    authors: Zunker P,Haase C,Borggrefe M,Georgiadis D,Georgiadis A,Ringelstein EB

    更新日期:1998-09-01 00:00:00

  • Prognostic value of perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage.

    abstract:OBJECTIVE:This study intends to investigate the prognostic value of perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage. METHODS:Demographic, clinical and biochemical data between acute intracerebral hemorrhage (AICH) and healthy volunteer groups were assessed in this study, such as rCBV an...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2016.1177932

    authors: Hu X,Bai X,Zai N,Sun X,Zhu L,Li X

    更新日期:2016-07-01 00:00:00

  • Positron emission tomographic evaluation of histological malignancy in gliomas using oxygen-15 and fluorine-18-fluorodeoxyglucose.

    abstract::HEADTOME III, a high resolution PET, has been employed using 15O and 18F labelled pharmaceuticals to evaluate histological malignancy of gliomas preoperatively. PET study was applied on eighteen preoperative gliomas including two recurrent cases. Haemocirculatory and metabolic indices of regional cerebral blood flow (...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1986.11739749

    authors: Mineura K,Yasuda T,Kowada M,Shishido F,Ogawa T,Uemura K

    更新日期:1986-09-01 00:00:00

  • Thrombin up-regulates vascular endothelial growth factor in experimental gliomas.

    abstract:OBJECTIVE:Vascular endothelial growth factor is a potent stimulator of angiogenesis; activation of hypoxia inducible factor-1alpha and p44/42 mitogen-activated protein kinase pathways has been associated with vascular endothelial growth factor production. The present study examined if thrombin modulates vascular endoth...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X385699

    authors: Xu Y,Gu Y,Keep RF,Heth J,Muraszko KM,Xi G,Hua Y

    更新日期:2009-09-01 00:00:00

  • A correlative analysis between inflammatory cytokines and trigeminal neuralgia or hemifacial spasm.

    abstract:BACKGROUND:It is necessary to understand the mechanism of trigeminal neuralgia (TN) and hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous studies implied that inflammatory cytokines induced by demyelination following the nerve injury may be the initiated factor causing neuropathic...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1564188

    authors: Liu MX,Zhong J,Xia L,Dou NN,Li ST

    更新日期:2019-04-01 00:00:00

  • Safely performing neurosurgical procedures during COVID-19 pandemic.

    abstract:INTRODUCTION:The novel coronavirus disease (COVID-19) pandemic poses a substantial threat to the health of healthcare personnel on the front line of caring for COVID-19 patients. The Centers for Medicare and Medicaid Services previously announced that all non-essential planned surgeries and procedures should be postpon...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2020.1781455

    authors: Reed LK,Wen J,Liang B,Wang X,Feng D,Huang JH

    更新日期:2020-10-01 00:00:00

  • Layered structure of saccular aneurysms assessed by collagen birefringence.

    abstract::Cerebral aneurysms are composed principally of collagen, a birefringent protein which is responsible for withstanding the forces of blood pressure. The known correlation between collagen birefringence and its mechanics provides the basis for using polarizing microscopy to evaluate the strength of collagen, layer by la...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1999.11740986

    authors: Canham PB,Finlay HM,Kiernan JA,Ferguson GG

    更新日期:1999-10-01 00:00:00

  • Comparative study among three different methods of bone marrow mesenchymal stem cell transplantation following cerebral infarction in rats.

    abstract::The objective of this study was to investigate the effects of transplanted bone marrow mesenchymal stem cells (BMSCs) administered via internal jugular vein injection, carotid artery injection, or intraventricular transplantation for the treatment of cerebral infarction, which was modeled in rats. The neurological sco...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132812Y.0000000152

    authors: Ruan GP,Han YB,Wang TH,Xing ZG,Zhu XB,Yao X,Ruan GH,Wang JX,Pang RQ,Cai XM,He J,Zhao J,Pan XH

    更新日期:2013-03-01 00:00:00

  • Serum leptin is associated with first-ever ischemic stroke, lesion size and stroke severity in a Chinese cohort.

    abstract:OBJECTIVE:Leptin may be associated with cardiovascular disease. We tested to determine whether leptin is a marker for first-ever acute ischemic stroke (AIS) in a nested case-referent study. METHODS:Consecutive patients with first-ever AIS from May 2017 to December 2017 were included. Referents were matched for sex, ag...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1544399

    authors: Liu G,Dong M,Ma S,Fu L,Xiao Y,Zhong L,Geng J

    更新日期:2019-02-01 00:00:00

  • A comparative study on clinical characterizations between acute myelitis onset of neuromyelitis optica spectrum disease and idiopathic transverse myelitis.

    abstract:BACKGROUND/AIMS:Both of neuromyelitis optica spectrum disease (NMOSDs) and idiopathic transverse myelitis (ITM) could present as acute transverse myelitis. However, long-term immunological treatment and prognosis are different for high recurrence of NMOSDs. In this study, we summarized clinical differences between acut...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2020.1773628

    authors: Liu Z,Xie M,Lu Z,Zhang C,Chen H,Xu Y,Zhang M

    更新日期:2020-07-01 00:00:00

  • [15O]-water PET and intraoperative brain mapping: a comparison in the localization of eloquent cortex.

    abstract::[15O]-water PET was performed on 12 patients with structural lesions for localization of the motor (n = 5), language (receptive and expressive; n = 6), and visual cortex (n = 1). All these patients underwent interactive image-guided surgery using an infrared digitizer and intraoperative electrical stimulation mapping ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1997.11740867

    authors: Viñas FC,Zamorano L,Mueller RA,Jiang Z,Chugani H,Fuerst D,Muzik O,Mangner TJ,Diaz FG

    更新日期:1997-12-01 00:00:00

  • Local fibrinolysis and aspiration of intracerebral hematomas in rats. An experimental study using MR monitoring.

    abstract::Serial magnetic resonance (MR) imaging has not yet been validated in the therapy of experimental intracerebral hematomas in a rat model. It is possible to test the effect of local fibrinolysis and aspiration on the clot volume using serial magnetic resonance imaging and different MR-sequences. Experiments were carried...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1998.11740530

    authors: Deinsberger W,Hartmann M,Vogel J,Jansen O,Kuschinsky W,Sartor K,Böker DK

    更新日期:1998-06-01 00:00:00

  • Minimum apparent diffusion coefficient for the differential diagnosis of ganglioglioma.

    abstract:OBJECTIVES:The utility of apparent diffusion coefficient (ADC) values was evaluated for the differential diagnosis of ganglioglioma. METHODS:Ten consecutive patients, five men and five women, aged from 14 to 67 years, with histologically proven supratentorial gangliogliomas, underwent diffusion-weighted magnetic reson...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X382539

    authors: Kikuchi T,Kumabe T,Higano S,Watanabe M,Tominaga T

    更新日期:2009-12-01 00:00:00

  • Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study.

    abstract::The decrease in intracellular creatine concentration in Duchenne muscular dystrophy may contribute to the deterioration of intracellular energy homeostasis and may thus be one of the factors aggravating muscle weakness and degeneration. Oral creatine supplementation should have potential in alleviating the clinical sy...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2000.11741051

    authors: Felber S,Skladal D,Wyss M,Kremser C,Koller A,Sperl W

    更新日期:2000-03-01 00:00:00

  • Association between Endothelial nitric oxide synthase G894T gene polymorphism and risk of ischemic stroke in North Indian population: a case-control study.

    abstract:BACKGROUND AND PURPOSE:Stroke is a multi-factorial disease influenced by both genetic and environmental factors. The aim of this case-control study was to determine the association between Endothelial Nitric Oxide Synthase G894T (rs1799983) gene polymorphism and susceptibility to ischemic stroke (IS) in North Indian po...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2016.1181376

    authors: Kumar A,Misra S,Kumar P,Sagar R,Prasad K,Pandit AK,Chakravarty K,Kathuria P,Yadav AK

    更新日期:2016-07-01 00:00:00

  • Mechanism of heat shock protein 72 induction in primary cultured astrocytes after oxygen-glucose deprivation.

    abstract::Induction of stress proteins is thought to be important in the protection of cells from a variety of environmental insults including heat, hypoxia and ischemia. The aim of this study was to compare the mechanism of induction of heat shock protein 72 (HSP72) in primary cultures of murine cortical astrocytes by heat and...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1996.11740380

    authors: Bergeron M,Mivechi NF,Giaccia AJ,Giffard RG

    更新日期:1996-02-01 00:00:00

  • Brain tissue oxygen tension in clinical brain death: a case series.

    abstract:OBJECTIVES:Brain death is a clinical diagnosis often confirmed with supplementary tests. In this study, we examined the relationship between brain death and the partial pressure of brain tissue oxygen (PbtO(2)). We hypothesized that a sustained PbtO(2) of 0 is associated with brain death. METHODS:One hundred and twent...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164107X208121

    authors: Smith ML,Counelis GJ,Maloney-Wilensky E,Stiefel MF,Donley K,LeRoux PD

    更新日期:2007-10-01 00:00:00

  • Tethered cord syndrome: overview of diagnosis and treatment.

    abstract::This article covers the basis of tethered cord syndrome as a stretch-induced spinal cord disorder, including pathophysiology, signs and symptoms, imaging diagnosis, indication for surgical treatment, and surgical procedures. Anomalies that cause mechanical spinal cord tethering are listed, and the surgical untethering...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/016164104225017947

    authors: Yamada S,Won DJ,Siddiqi J,Yamada SM

    更新日期:2004-10-01 00:00:00

  • Severity dependent up-regulations of LOX-1 and MCP-1 in early sclerotic changes of common carotid arteries in spontaneously hypertensive rats.

    abstract::Lectin-like oxidized low-density lipoprotein receptor (LOX-1) and monocyte chemoattractant protein-1 (MCP-1) are molecules involving in the initiation and progression of atherosclerosis. In order to examine a possible difference in LOX-1 and MCP-1 expressions depending on the severity of early stage of atherosclerosis...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164104225016074

    authors: Hamakawa Y,Omori N,Ouchida M,Nagase M,Sato K,Nagano I,Shoji M,Fujita T,Abe K

    更新日期:2004-10-01 00:00:00

  • Endovascular treatment of congenital carotid-cavernous fistulas in infancy.

    abstract::Congenital dural arteriovenous fistulas have been infrequently described in pediatric population and they generally affect the transverse, sigmoid, straight or sagittal sinuses. Congenital carotid-cavernous fistulas in infancy are considered very rare and to our knowledge, only four cases have been reported in literat...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313208X291612

    authors: Cohen JE,Gomori JM,Grigoriadis S,Rajz G

    更新日期:2008-07-01 00:00:00

  • Direct ethanol injection for skull metastasis from hepatocellular carcinoma. The techniques and consequences of a therapeutic trial.

    abstract::The frequency of skull metastasis from hepatocellular carcinoma (HCC) is increasing together with the recent progress in the management of the primary lesion. Cases are often complicated with poor general conditions or metastasis to the other organs, and not readily indicated for surgery. A direct injection of ethanol...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1998.11740593

    authors: Isaka T,Yoshimine T,Fujimoto K,Masuzawa M,Maruno M,Hayakawa T,Nakatani S

    更新日期:1998-12-01 00:00:00

  • Bone marrow mesenchymal stem cells can improve the motor function of a Huntington's disease rat model.

    abstract:OBJECTIVES:The purpose of this study was to investigate the ability of bone marrow mesenchymal stem cells (BMSCs) to survive in the striatum and improve motor function in the quinolinic acid (QA) lesion rat model of Huntington's disease (HD). METHODS:One week following QA lesioning of the striatum, rats were transplan...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164110X12816242542571

    authors: Jiang Y,Lv H,Huang S,Tan H,Zhang Y,Li H

    更新日期:2011-04-01 00:00:00

  • Asymptomatic circulating cerebral emboli and cerebral blood flow velocity under aspirin and ticlopidine in patients with cerebrovascular disease.

    abstract::Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/01616412.1996.11740450

    authors: Droste DW,Sonne M,Siemens HJ,Kaps M

    更新日期:1996-10-01 00:00:00

  • Anti-GQ1b IgG antibody activities related to the severity of Miller Fisher syndrome.

    abstract::The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章

    doi:10.1080/01616412.1998.11740573

    authors: Mizoguchi K

    更新日期:1998-10-01 00:00:00

  • Quantitative analysis of early postoperative cerebral blood flow contributes to the prediction and diagnosis of cerebral hyperperfusion syndrome after revascularization surgery for moyamoya disease.

    abstract:OBJECTIVE:Cerebral hyperperfusion syndrome (HPS) is a potential complication of extracranial-intracranial (EC-IC) bypass for moyamoya disease; however, the pathological threshold of the early cerebral blood flow (CBF) increases after EC-IC bypass has yet to be determined. The purpose of this study is to evaluate the pr...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132814Y.0000000432

    authors: Fujimura M,Niizuma K,Endo H,Sato K,Inoue T,Shimizu H,Tominaga T

    更新日期:2015-02-01 00:00:00

  • Neurological aspects of tuberous sclerosis in relation to MRI/MR spectroscopy findings in children with epilepsy.

    abstract::Our aim was to evaluate the relationship between the neurological outcome of tuberous sclerosis complex (TSC) and the findings obtained from both cranial magnetic resonance imaging (MRI) and single voxel proton spectroscopy (SVPS). MRIs of 13 children who met the diagnostic criteria for TSC were taken. Eleven of these...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164107X163996

    authors: Yapici Z,Dörtcan N,Baykan BB,Okan F,Dinçer A,Baykal C,Eraksoy M,Roach S

    更新日期:2007-07-01 00:00:00

  • Alzheimer's disease like pathology induced six weeks after aggregated amyloid-beta injection in rats: increased oxidative stress and impaired long-term memory with anxiety-like behavior.

    abstract:OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2016.1209337

    authors: Sharma S,Verma S,Kapoor M,Saini A,Nehru B

    更新日期:2016-09-01 00:00:00

  • The relationship between brain microbleeds and homeostatic markers in the treatment of ischemic stroke.

    abstract:OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1517111

    authors: Altintas O,Niftaliyev E,Asil T

    更新日期:2018-12-01 00:00:00

  • CT perfusion in predicting the morbidity and prognosis of hypoxic-ischemic encephalopathy after off-pump coronary artery bypass grafting.

    abstract:OBJECTIVE:To investigate the perfusion parameters of computed tomography (CT) in hypoxicischemic encephalopathy (HIE) after off-pump coronary artery bypass grafting (OPCABG), and its potential in predicting the occurrence and prognosis of hypoxic-ischemic encephalopathy. METHODS:We selected 830 patients. The patients ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2017.1315862

    authors: Luo D,Yip J,Song Z,Xu B,Bi Q

    更新日期:2017-06-01 00:00:00