Abstract:
:The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum samples were obtained from all the patients within the first 2 weeks of onset and from 12 of them 4 weeks after onset. Samples were immunostained by TLC after which antibody activities were measured by the ELISA. Anti-GQ1b IgG antibody activities reflect the severity of the patients' symptoms, especially ophthalmoplegia. Lessening of symptoms, expressed by the difference in MFS severity scores of the two tests, occurred with the marked decrease in antibodies. Results of cerebrospinal fluid and nerve conduction studies, performed during the first 2 weeks, showed no fluctuation with changes in the clinical symptoms or antibody activities.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Mizoguchi Kdoi
10.1080/01616412.1998.11740573subject
Has Abstractpub_date
1998-10-01 00:00:00pages
617-24issue
7eissn
0161-6412issn
1743-1328journal_volume
20pub_type
临床试验,杂志文章abstract:OBJECTIVE:Tadalafil is a selective phosphodiesterase type 5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction. Less is known about the electroencephalography (EEG) effects of PDE-5 inhibitors, and the present study, therefore, examined the risk of EEG abnormalities associated with tadalafil. METHOD:...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X382548
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:This study investigated the role of matrix metalloproteinase-9 (MMP-9) in early brain injury after subarachnoid hemorrhage (SAH). METHOD:Sprague-Dawley male rats (n=36) weighing between 250 and 300 g were used. SAH was produced by injecting autologous arterial blood into the pre-chiasmatic cistern. MMP-9 pro...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164109X12478302362491
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To investigate risk factors for neurological complications after off-pump coronary artery bypass grafting (OPCABG). METHODS:We reviewed the cases of 813 patients who underwent OPCABG between August 2010 and September 2013.Data from preoperative 320 dynamic volume computed tomography (CT), CT angiography (CTA...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132815Y.0000000030
更新日期:2015-05-01 00:00:00
abstract::Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2019.1685064
更新日期:2020-01-01 00:00:00
abstract::The therapeutic effect of insulin alone or insulin combined with 30 min delayed thrombolytic therapy was investigated in rats embolized in the right hemisphere with a fibrin clot made from autologous blood. Animals were killed seven days after embolization and the infarct volumes were measured in % of the affected hem...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164102101200096
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164110X12644252260592
更新日期:2010-04-01 00:00:00
abstract::Recent publications have suggested that intra-ocular pressure (IOP) may be an indirect assessment of intra-cranial pressure (ICP). Both IOP and ICP have similar physiologic pressure ranges and similar responses to changes in intra-abdominal, intra-thoracic and aortic pressure. Previous studies have demonstrated the re...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1999.11740925
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:To investigate the perfusion parameters of computed tomography (CT) in hypoxicischemic encephalopathy (HIE) after off-pump coronary artery bypass grafting (OPCABG), and its potential in predicting the occurrence and prognosis of hypoxic-ischemic encephalopathy. METHODS:We selected 830 patients. The patients ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1315862
更新日期:2017-06-01 00:00:00
abstract::The effect of labetalol, a combined alpha- and beta-adrenoceptor antagonist, on the cerebral circulation was investigated in 7 normotensive subjects. Cerebral blood flow (CBF) was measured with the intravenous 133Xe method and mean flow velocity (Vmean) in the middle cerebral artery was determined using transcranial D...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1991.11739958
更新日期:1991-03-01 00:00:00
abstract::One case of dural arteriovenous malformation in the base of the anterior cranial fossa is reported. It was discovered by means of a PW-Doppler examination of angular branch of the ophthalmic artery in a patient under observation for hypertrophy of a superficial temporal artery. The nidus was located in the region of t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1995.11740317
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker that is associated with the outcomes of ischemic stroke. However, the role of hs-CRP levels in the functional outcomes after large-artery atherosclerosis (LAA) and small-artery occlusion (SAO) is poorly understood. METHODS:We recruited 1...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1358937
更新日期:2017-11-01 00:00:00
abstract::We postulate that severe atherosclerotic occlusion of the circle of Willis and leptomeningeal arteries is an important factor in the pathogenesis of some sporadic Alzheimer's disease (AD) cases. These arterial stenoses are complicated by an overwhelming amyloid accumulation in the walls of leptomeningeal and cortical ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164104225017668
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:Chronic subdural hematoma (cSDH) has an increasing incidence and results in high morbidity and mortality. We review here the 10-year experience of a single institution and the literature regarding the treatment and major associations of cSDH. METHODS:We retrospectively reviewed all cSDHs surgically treated f...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/1743132813Y.0000000166
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1209337
更新日期:2016-09-01 00:00:00
abstract::In this work, we evaluated the differences between epileptic electroencephalogram (EEG) and interictal EEG by computing some non-linear features. Correlation dimension (CD) and Hurst exponent (H) were calculated for 100 segments of epileptic EEG and 100 segments of interictal EEG. A comparison was made between epilept...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132811Y.0000000041
更新日期:2011-11-01 00:00:00
abstract::Intravenous infusion of glycerol has been used in patients with a cerebral infarction, expecting improvement in brain edema and cerebral blood flow (CBF). However, the mechanism of the improvement of CBF has not been clearly demonstrated. The aim of this study in the rat pial microvasculature after transient middle ce...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1999.11741015
更新日期:1999-12-01 00:00:00
abstract::Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...
journal_title:Neurological research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/01616412.1996.11740450
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVES:This study sought to compare the atherosclerotic plaque burden between middle cerebral artery (MCA) and extracranial carotid artery (ECA) in ischemic stroke patients using high-resolution, black-blood (HR BB) MRI and to investigate the relationship between plaque burden found in both arteries and stroke seve...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1281196
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:To assess prospectively the significance of sonographic measurements of the median nerve in the diagnosis of carpal tunnel syndrome (CTS), to look for proper parameters and cutoff values for the sonographic diagnosis, and to correlate with the electrophysiological findings. MATERIALS AND METHODS:This study ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132811Y.0000000028
更新日期:2011-11-01 00:00:00
abstract::Neuronal nitric oxide synthase (nNOS) regulates neurogenesis in normal developing brain, but the role of nNOS in neurogenesis in the ischemic brain remains unclear. To investigate the temporal and spatial relationship between cell proliferation of the ependymal/subventricular zone (SVZ), a principal neuroproliferative...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164106X91942
更新日期:2006-01-01 00:00:00
abstract::Objective: To assess the neuropsychological status of pediatric multiple sclerosis (MS) patients and its relationship with clinical variables in a longitudinal study.Methods: Patients with MS (n = 46) and age- and gender-matched healthy control subjects (HCs, n = 53) were given tests of non-verbal reasoning, attention...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2019.1710417
更新日期:2020-02-01 00:00:00
abstract::Cerebral aneurysms are composed principally of collagen, a birefringent protein which is responsible for withstanding the forces of blood pressure. The known correlation between collagen birefringence and its mechanics provides the basis for using polarizing microscopy to evaluate the strength of collagen, layer by la...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1999.11740986
更新日期:1999-10-01 00:00:00
abstract::Recent evidence indicates that different vascular risk factors are present in Alzheimer's disease (AD) and other prevalent dementia types probably contributing to deterioration of cerebrovascular function, thus enhancing neurodegeneration and premature neuronal death due to a reduction in brain perfusion. Brain blood ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164103101202002
更新日期:2003-09-01 00:00:00
abstract::The haemodynamic mechanisms responsible for the appearance of paraparetic transient ischaemic attacks in ten patients with childhood moyamoya disease who subsequently underwent bifrontal omental transplantation were investigated. Cerebral perfusion (CP) was measured with 99mTc-hexamethylene-propyleneamine oxime single...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1995.11740306
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the ability of bone marrow mesenchymal stem cells (BMSCs) to survive in the striatum and improve motor function in the quinolinic acid (QA) lesion rat model of Huntington's disease (HD). METHODS:One week following QA lesioning of the striatum, rats were transplan...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12816242542571
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X385617
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To establish a detailed technical procedure for studying the anatomical correlates of chronic cerebrospinal venous insufficiency in cadavers of multiple sclerosis and control subjects, and to present our findings of the normal anatomic venous structures, with reference to previous descriptions from the liter...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000071
更新日期:2012-10-01 00:00:00
abstract::Objective: Nowadays, retinal microvascular structures can be investigated using optical coherence tomography angiography (OCTA). We aimed to evaluate the probable vascular changes in the foveal and peripapillary regions of patients with multiple sclerosis (MS).Methods: A total of 20 patients with relapsing remitting m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1726585
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS. METHODS:Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1792700
更新日期:2020-11-01 00:00:00
abstract::Neural stem cells (NSCs) are self-renewable, multipotential cells capable of differentiating into the three major neural cell types, but the mechanisms which regulate their development are not fully understood. Both basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) promote the proliferation of NS...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199090
更新日期:2001-09-01 00:00:00