Prognostic value of perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage.

Abstract:

OBJECTIVE:This study intends to investigate the prognostic value of perfusion-weighted magnetic resonance imaging in acute intracerebral hemorrhage. METHODS:Demographic, clinical and biochemical data between acute intracerebral hemorrhage (AICH) and healthy volunteer groups were assessed in this study, such as rCBV and MTT values. The optimal cutoff values of rCBV and MTT for diagnosing AICH were determined by the ROC curves. Apart from that, we also investigated the association between rCBV/MTT values and cerebral hematoma volumes of AICH patients. The unconditional logistic regression was conducted to determine significant risk factors for AICH. RESULT:AICH patients have significantly lower rCBV and higher MTT compared to the control group (all P < 0.05). As suggested by the relatively high sensitivity and specificity, both rCBV and MTT values could be utilized for AICH diagnosis. Moreover, rCBV and MTT were significantly associated with the cerebral hematoma volumes of AICH patients (all P < 0.05). Results from unconditional logistic regression analysis revealed that MTT was a significant risk factor for AICH (P < 0.05 and OR > 1), while rCBV is considered as a protective factor (P < 0.05 and OR < 1). CONCLUSION:Perfusion-weighted magnetic resonance imaging produces a high prognostic value for diagnosing AICH.

journal_name

Neurol Res

journal_title

Neurological research

authors

Hu X,Bai X,Zai N,Sun X,Zhu L,Li X

doi

10.1080/01616412.2016.1177932

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

614-9

issue

7

eissn

0161-6412

issn

1743-1328

journal_volume

38

pub_type

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