Abstract:
:Supraventricular and ventricular tachyarrhythmia are established causes of syncope. We investigated the mean blood flow velocities (Vmean) of the middle cerebral arteries (MCA) during routine cardiac electrophysiologic studies in patients with supraventricular and ventricular tachyarrhythmias in order to evaluate the changes in cerebral hemodynamics associated with pre-syncopal and syncopal states. Thirty-two patients with a history of supraventricular (n = 14) or ventricular (n = 18) tachyarrhythmias were investigated in the nonsedated, post-absorptive state in supine position. Vmean was assessed in both MCAs by means of transcranial Doppler under resting conditions, during atrial and ventricular pacing at constant rates (n = 28) and during induction of tachyarrhythmia (n = 4). Mean arterial blood pressure (MABP) and heart rate were also recorded. Seven patients suffered pre-syncope at a heart rate of 187 +/- 45 bpm (mean +/- SD) with an average drop of 44% in the Vmean MCA, and statistically insignificant changes in MABP. Five patients suffered syncope during tachyarrhythmia (mean heart rate 283 +/- 42 bpm) with a reduction of 69% in the Vmean MCA. MABP could be assessed in two of those patients and showed a drop of 15 and 43 mmHg, respectively. During tachyarrhythmia pre-syncope and syncope are associated with an average reduction in Vmean MCA by 44% and 69%, respectively. The decrease in MCA blood flow velocity is a more important predictive factor for the development of pre-syncope and syncope than the MABP.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Zunker P,Haase C,Borggrefe M,Georgiadis D,Georgiadis A,Ringelstein EBdoi
10.1080/01616412.1998.11740555subject
Has Abstractpub_date
1998-09-01 00:00:00pages
504-8issue
6eissn
0161-6412issn
1743-1328journal_volume
20pub_type
杂志文章abstract:OBJECTIVE:This study examined whether a needle-free acupuncture can be an alternative to conventional needle injection acupuncture. METHODS:Patients (n=101) suffering myofascial shoulder pain were randomly assigned to either needle-free or conventional needle injection acupuncture group. Bee venom was administered int...
journal_title:Neurological research
pub_type: 杂志文章,随机对照试验
doi:10.1179/016164109X12537002793760
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION:Cerebrospinal fluid (CSF) oligoclonal bands (OB) imply intrathecal immunoglobulin synthesis and B-cell immune process. There is scarce evidence of OB having a role in disease prognosis. The objective of the present study was to determine OB's prognostic value regarding disease progression. METHODS:Betwee...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000088
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to analyse inflammatory cells in lumbar disc tissue under cyclooxygenase-2 (COX-2) inhibitor therapy, to detect their prevalence in different subtypes of lumbar disc herniations and to assess the influence of inflammatory reactions in herniated disc tissue on postoperative out...
journal_title:Neurological research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1179/016164105X49210
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the effects of oral administration of a novel benzodiazepine derivative, JM-20, on the neurological behavior of different rodent models, focusing on the GABAergic effect. We have also investigated the acute toxicity of oral administration of JM-20 in mice. METHODS:Mi...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000216
更新日期:2013-10-01 00:00:00
abstract::The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199388
更新日期:2001-12-01 00:00:00
abstract::In this work, we evaluated the differences between epileptic electroencephalogram (EEG) and interictal EEG by computing some non-linear features. Correlation dimension (CD) and Hurst exponent (H) were calculated for 100 segments of epileptic EEG and 100 segments of interictal EEG. A comparison was made between epilept...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132811Y.0000000041
更新日期:2011-11-01 00:00:00
abstract::Rats were exposed in utero plus 60 days post-partum to either complex music (Mozart Sonata (k. 448)), minimalist music (a Philip Glass composition), white noise or silence, and were then tested for five days, three trials per day, in a multiple T-maze. By Day 3, the rats exposed to the Mozart work completed the maze m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740543
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:High blood pressure (BP) is a major risk factor for stroke and all of its pathological subtypes including subarachnoid hemorrhage (SAH). However, there is little evidence demonstrating whether failure to have regular BP measured could result in underestimation of people at risk for SAH. Therefore, we aimed ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132811Y.0000000020
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:Intracranial aneurysms (IAs) of the posterior circulation (PC) rupture more frequently and their morbidity and mortality rates are higher compared to anterior circulation. Morphological parameters such as size ratio (SR), inflow angle and parent artery geometry are believed to contribute significantly in det...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000306
更新日期:2014-08-01 00:00:00
abstract::Objectives: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). Methods: Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.5 h, 6...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2019.1672388
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Traumatic brain injuries (TBIs) cause a substantial burden to the patient, relatives, and the society as a whole. Much experience and knowledge during the last two decades have improved the neurosurgical treatment as well as the outcome. However, there is still much debate on what actually happens when exter...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000227
更新日期:2013-10-01 00:00:00
abstract::The possibility of the evaluation of ischemia solely by the momentary values of regional cerebral blood flow (rCBF) was investigated. Ischaemic damage was evaluated histopathologically and by observing albumin extravasation. Unilateral carotid clippings were performed for 1 h and the gerbils evaluated with regard to t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1988.11739846
更新日期:1988-12-01 00:00:00
abstract::Based on the successful use of fetal striatal brain grafting in the restoration of striatal function in rat and nonhuman primate models of Huntington's disease, as well as on the evidence for the clinical potential of fetal brain grafting in the treatment of Parkinson's disease, homotopic fetal striatal homotransplant...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1995.11740334
更新日期:1995-08-01 00:00:00
abstract::The craniocervical regions of seven cadavers (14 sides) injected with silicone rubber were dissected under a Zeiss OPMI surgical microscope. The present study provides a detailed description of the suboccipital segment of the vertebral artery, with particular attention to its loops, branches, supporting osteofibrous s...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740507
更新日期:1998-04-01 00:00:00
abstract::Objectives: Brain arteriovenous malformations (AVMs) represent high-flow vascular lesions made up of a complex network of feeding arteries and draining veins interposed by a nidus and without a capillary bed. The management of the AVMs represents a challenge, and the optimal treatment should be considered based on the...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1803604
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:This study investigated the role of matrix metalloproteinase-9 (MMP-9) in early brain injury after subarachnoid hemorrhage (SAH). METHOD:Sprague-Dawley male rats (n=36) weighing between 250 and 300 g were used. SAH was produced by injecting autologous arterial blood into the pre-chiasmatic cistern. MMP-9 pro...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164109X12478302362491
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:Surgical management of sphenoorbital meningiomas ranges among the most complex of intracranial tumors. We report on our experience of surgical technique, outcome, and tumor recurrence in sphenoorbital meningiomas. METHODS:Between 2003 and 2013, surgical resections for sphenoorbital meningioma were performed ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132814Y.0000000329
更新日期:2014-08-01 00:00:00
abstract::Objective: Nowadays, retinal microvascular structures can be investigated using optical coherence tomography angiography (OCTA). We aimed to evaluate the probable vascular changes in the foveal and peripapillary regions of patients with multiple sclerosis (MS).Methods: A total of 20 patients with relapsing remitting m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2020.1726585
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1179/016164108X323753
更新日期:2008-11-01 00:00:00
abstract::Using the previously reported method of experimental localized brainstem infarct in dogs, we designed this study to elucidate sequential changes of regional cerebral blood flow (rCBF) in three separate regions of the central nervous system: the cerebral cortex, thalamus, and midbrain. The data obtained were referred t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2000.11741061
更新日期:2000-03-01 00:00:00
abstract::A computer software program (Seapit) was developed for precise determination of intracranial targets identified by stereotactic computed tomography (CT). This program was added to the software of a GE 8800 CT scanner to perform the following operations: millimetre precise calculation and display of the rectilinear coo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1987.11739781
更新日期:1987-06-01 00:00:00
abstract::The influence of acidic fibroblast growth factor (aFGF) on sleep was studied in conscious rabbits. An intravenous (i.v.) bolus injection of aFGF induced a significant increase in sleep duration in comparison with animals that received vehicle solution. Somnogenic effects were obtained 30 min following i.v. aFGF admini...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1996.11740472
更新日期:1996-12-01 00:00:00
abstract::The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1080/01616412.1998.11740573
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVES:Progesterone modulates dopamine (DA) release in corpus striatum. Our objective was to evaluate the effect of the i.c.v injection of the neurosteroid allopregnanolone (ALL), a progesterone metabolite on dopaminergic activity in the corpus striatum of rats under different gonadal hormonal conditions. METHODS:...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X166281
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:The feasibility of high resolution CT imaging for evaluating experimentally-induced brain tumors in rats was assessed. METHODS:The gliosarcoma cell line (9 L/lacZ) was inoculated in 34 male Fischer 344 rats and CT studies were performed prior to and at 4, 7, 9, 12 and 14 days post-tumor cell implantation. Br...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X18250
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the ability of bone marrow mesenchymal stem cells (BMSCs) to survive in the striatum and improve motor function in the quinolinic acid (QA) lesion rat model of Huntington's disease (HD). METHODS:One week following QA lesioning of the striatum, rats were transplan...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12816242542571
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:It is difficult for the treatment of neurologic tumors with current therapies, including glioma. Despite the advances in cancer therapeutics, the outcomes in these patients remain poor and, therefore, new modalities are required. Recent findings have demonstrated that human umbilical cord blood mesenchymal st...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164110X12816242542490
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:In order to test for mechanisms of whole brain radio therapy side effects and possible neuroprotective measures, a rodent model is desirable. In many models, a high single dose of 8-20 Gray (Gy) of whole brain irradiation is used. These experimental radiation protocols do not closely reflect the clinical situ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000143
更新日期:2013-05-01 00:00:00
abstract::Various surgical approaches have been described for treating lesions which arise in the sellar region. The popular transnasal-transsphenoidal and transethmoidal-transsphenoidal approaches avoid the morbidity associated with transcranial operations while allowing enough exposure to successfully remove most lesions that...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198280
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:Although magnesium is a well-known treatment for vasospasm following subarachnoid hemorrhage, its mechanism of action for cerebral vascular relaxation is not clear. In addition, it is known that L-type calcium (Ca(2+)) channels play a pivotal role in smooth muscle contraction. To investigate the role of L-t...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000016
更新日期:2012-04-01 00:00:00