Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.

Abstract:

:Cerebral vasospasm and/or delayed ischaemic state following subarachnoid haemorrhage still remain unsolved serious problems. With the development and introduction of calcium antagonists as well as the advances in perioperative management, however, the clinical outcome has much improved in recent years. Among such drugs, nimodipine and nicardipine are those, of which effectiveness on the vasospasm or delayed ischaemic changes was demonstrated by several double-blind placebo-controlled studies. This paper reviews the current status of the calcium antagonists used in the management of subarachnoid haemorrhage, focusing mainly on the clinical study.

journal_name

Neurol Res

journal_title

Neurological research

authors

Hongo K,Kobayashi S

doi

10.1080/01616412.1993.11740140

subject

Has Abstract

pub_date

1993-08-01 00:00:00

pages

218-24

issue

4

eissn

0161-6412

issn

1743-1328

journal_volume

15

pub_type

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