Abstract:
:Magnetic resonance (MR) is a powerful new imaging modality which has recently become competitive with X-ray computed tomography (CT) for imaging of the central nervous system (CNS). The advantages of MR include lack of ionizing radiation and the necessity to use iodinated contrast. MR is able to image directly in the transaxial, coronal, and sagittal planes. With appropriate pulsing sequences, MR is more sensitive than CT in the detection of early disease associated with increased water content. Included in this category are multiple sclerosis, early infarcts, small tumours, and inflammatory lesions. MR is superior to CT in the posterior fossa due to beam hardening artifacts in the latter modality. In the cord, MR is useful in the evaluation of syringomyelia, spinal dysraphism, and intramedullary tumours. Due to its increased sensitivity in the detection of early disease, MR should generally be used as the initial screening procedure in the evaluation of possible intracranial disease. Current limitations of MR include longer single slice imaging times, thicker slices, inability to use contrast agents to define blood/brain barrier breakdown, and the inability to image calcification and cortical bone. Patients on cardiac monitors or on respirators and those with intracranial aneurysm clips and cardiac pacemakers are currently excluded from MR imaging.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Bradley WG Jrdoi
10.1080/01616412.1984.11739671subject
Has Abstractpub_date
1984-09-01 00:00:00pages
91-106issue
3eissn
0161-6412issn
1743-1328journal_volume
6pub_type
杂志文章,评审abstract:BACKGROUND AND PURPOSE:Studies have shown that awareness of early stroke symptoms and the use of ambulances are two important factors in decreasing pre-hospital stroke delay. The purpose of this study is to evaluate a comprehensive educational stroke protocol in improving stroke response times. METHOD:Two urban commun...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000203
更新日期:2013-06-01 00:00:00
abstract::The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1080/01616412.1998.11740573
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVES:The goals of the present study are to obtain, expand and characterize a stem cell population from human omentum and to evaluate its in vivo angiogenic capacities. METHODS:Human omental CD34+ cells were obtained from samples of human omentum by density gradient centrifugation in Ficoll. Proliferative pattern...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X63674
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke is a multi-factorial disease influenced by both genetic and environmental factors. The aim of this case-control study was to determine the association between Endothelial Nitric Oxide Synthase G894T (rs1799983) gene polymorphism and susceptibility to ischemic stroke (IS) in North Indian po...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1181376
更新日期:2016-07-01 00:00:00
abstract::The possible role of nitric oxide (NO) on vibrissa-stimulated increase of regional cerebral cerebral blood flow (rCBF) and cerebral metabolic rate of glucose (rCMRglu) was investigated in conscious Wistar rats by using an inhibitor of NO synthase, NG-nitro-L-arginine (NOLAG) at a concentration of 30 mg/kg. In vivo aut...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1993.11740103
更新日期:1993-02-01 00:00:00
abstract::To study the pathophysiology of olivopontocerebellar atrophy (OPCA), we destroyed inferior olive nuclei of male Wistar rats using 3-acetyl pyridine (3-AP) + harmaline + niacinamide. These rats showed a sluggish and ataxic gait. To elucidate the relationship between thyrotropin releasing hormone (TRH) in the Purkinje c...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2000.11740690
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Mapping of brain perfusion using bolus tracking methods is increasingly used to assess the amount and severity of cerebral ischemia in acute stroke. Using relative perfusion maps, however, it is difficult to identify the tissue at risk-maximum (TARM) of infarction with sufficient reliability and reproducibil...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X158956
更新日期:2007-04-01 00:00:00
abstract::A computer software program (Seapit) was developed for precise determination of intracranial targets identified by stereotactic computed tomography (CT). This program was added to the software of a GE 8800 CT scanner to perform the following operations: millimetre precise calculation and display of the rectilinear coo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1987.11739781
更新日期:1987-06-01 00:00:00
abstract::The aim of this study was to examine the pre-operative clinical and neuromonitoring courses in patients with a decompressive craniectomy to assess and to compare clinical and neuromonitoring signs indicating extensive cerebral edema. We conducted a retrospective analysis of the clinical signs and courses of simultaneo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164103101201742
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1179/016164108X323753
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:The utility of apparent diffusion coefficient (ADC) values was evaluated for the differential diagnosis of ganglioglioma. METHODS:Ten consecutive patients, five men and five women, aged from 14 to 67 years, with histologically proven supratentorial gangliogliomas, underwent diffusion-weighted magnetic reson...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X382539
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:To estimate the incidence of cognitive impairment (CI) among cognitively healthy, Mexican subjects, and to evaluate the impact of demographic and vascular factors on the conversion to CI and mortality. METHODS:734 eligible subjects (aged 55 to >90 years) from a population-based sample were examined. The cog...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X49427
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVES:To review the use of immunoassays in the diagnosis and research of disorders affecting the nervous system. METHODS:Systematic review of the English literature. RESULTS:Immunoassays have demonstrated utility for: (1) the detection of antigen (molecules, genes, gene products, peptides, hormones and drug meta...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164105X49535
更新日期:2005-10-01 00:00:00
abstract::Although neuronal death has been studied in experimental models of ischemia, the precise mechanisms regulating cell death remain unclear. Furthermore, the timing and pattern of neuronal death in human stroke has not been extensively studied. To further our understanding of ischemia-induced neuronal death, we examined ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740520
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:Patients presenting to the emergency room with an acute or subacute onset of focal neurological deficits are evaluated initially by non-contrast computed tomogram (CT) of the brain. This is primarily carried out to differentiate an ischemic from hemorrhagic stroke. However, other neurological conditions may ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164109X12445505689607
更新日期:2009-10-01 00:00:00
abstract::The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101199388
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:Interleukin-21 (IL-21) is a cytokine that is an important modulator of immune responses. However, its roles in epilepsy are not completely clear. Here, we investigated the expression and distribution of IL-21 in a kainic acid (KA)-induced acute seizure mouse model. MATERIALS AND METHODS:Mice (n = 146) were r...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2015.1135557
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Cerebral hyperperfusion syndrome (HPS) is a potential complication of extracranial-intracranial (EC-IC) bypass for moyamoya disease; however, the pathological threshold of the early cerebral blood flow (CBF) increases after EC-IC bypass has yet to be determined. The purpose of this study is to evaluate the pr...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132814Y.0000000432
更新日期:2015-02-01 00:00:00
abstract::The association between glucocerebrosidase (GBA) mutations and Parkinson's disease (PD) is attracting increased attention worldwide. Results from previous studies on the association of GBA mutations with PD in different ethnicities remain contradictory. In order to derive a more comprehensive understanding of the rela...
journal_title:Neurological research
pub_type: 杂志文章,meta分析,评审
doi:10.1179/1743132813Y.0000000224
更新日期:2013-10-01 00:00:00
abstract::Previous work has shown that unsaturated fatty acid components of model membrane phospholipids in vitro, damaged via a free radical mechanism, are protected by the presence of cholesterol in these membranes. The participation of these membrane lipids in the pathogenesis of traumatic injury to brain was studied in vivo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1981.11739608
更新日期:1981-01-01 00:00:00
abstract::An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1980.11739588
更新日期:1980-01-01 00:00:00
abstract::Recent evidence indicates that different vascular risk factors are present in Alzheimer's disease (AD) and other prevalent dementia types probably contributing to deterioration of cerebrovascular function, thus enhancing neurodegeneration and premature neuronal death due to a reduction in brain perfusion. Brain blood ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164103101202002
更新日期:2003-09-01 00:00:00
abstract::Endovascular reconstruction of basilar artery (BA) apex aneurysms has been augmented by adjunctive techniques such as balloon and stent assistance. We present three cases of a wide-necked BA apex aneurysm involving the bilateral P1 segments of both posterior cerebral arteries (PCAs) treated by placement of BA to PCA s...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164104225013969
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:Neuropsychological outcomes after carotid endarterectomy (CEA) have been investigated extensively. However, cognitive impacts of carotid angioplasty and stenting (CAS), an emerging alternative to CEA, have not been studied. This study is aimed at investigating pattern and degree of cognitive changes after CAS...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X159216
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To investigate the perfusion parameters of computed tomography (CT) in hypoxicischemic encephalopathy (HIE) after off-pump coronary artery bypass grafting (OPCABG), and its potential in predicting the occurrence and prognosis of hypoxic-ischemic encephalopathy. METHODS:We selected 830 patients. The patients ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1315862
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:Transient ischemic attack (TIA) with carotid artery disease (CAD) can increase the risk of cognitive decline. However, the neural mechanisms of the disorder remain unclear. The aim of this study was, using diffusion tensor imaging (DTI), to detect microstructural changes in patients with symptomatic CAD pres...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132813Y.0000000255
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To establish a detailed technical procedure for studying the anatomical correlates of chronic cerebrospinal venous insufficiency in cadavers of multiple sclerosis and control subjects, and to present our findings of the normal anatomic venous structures, with reference to previous descriptions from the liter...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132812Y.0000000071
更新日期:2012-10-01 00:00:00
abstract::This paper reviews our recent studies of the role of cortical spreading depression (CSD) in the pathogenesis of brain disorders. Our investigation is a computational one, involving the development and utilization of a complex neuro-metabolic model of the interactions assumed to occur in the cortex during the passage o...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198839
更新日期:2001-07-01 00:00:00
abstract::The frequency of skull metastasis from hepatocellular carcinoma (HCC) is increasing together with the recent progress in the management of the primary lesion. Cases are often complicated with poor general conditions or metastasis to the other organs, and not readily indicated for surgery. A direct injection of ethanol...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740593
更新日期:1998-12-01 00:00:00
abstract::The present study was designed to investigate the beneficial effects of cornel iridoid glycoside (CIG), a main component extract from Cornus officinalis, on neurotrophin expression in mouse experimental autoimmune encephalomyelitis (EAE), a classical model of multiple sclerosis (MS). After EAE initiation, CIG was intr...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1200766
更新日期:2016-09-01 00:00:00