Fructose-added glycerol (Glyceol) for therapy of elevated intracranial pressure: analysis of the side effects of long-term administration in a multi-institutional trial.

abstract：:The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and a...

journal_title：Neurological research

authors： Robertson J,Timmons S

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:Patent foramen ovale (PFO) is considered as an important risk factor for cerebrovascular diseases. Nevertheless, the relationship between the distribution of high-intensity transient signals (HITS), resulting from injection of air mixed with saline and detected by transcranial Doppler (TCD), and clinical cer...

journal_title：Neurological research

authors： Telman G,Kouperberg E,Sprecher E,Goldsher D,Yarnitsky D

更新日期：2005-01-01 00:00:00

abstract：:The present study was designed to investigate the beneficial effects of cornel iridoid glycoside (CIG), a main component extract from Cornus officinalis, on neurotrophin expression in mouse experimental autoimmune encephalomyelitis (EAE), a classical model of multiple sclerosis (MS). After EAE initiation, CIG was intr...

journal_title：Neurological research

authors： Qu Z,Zheng N,Zhang Y,Zhang L,Liu J,Wang Q,Yin L

更新日期：2016-09-01 00:00:00

abstract：:The spontaneous disappearance and reappearance of a ruptured cerebral aneurysm is generally assumed to be a rare phenomenon although the actual incidence is unknown. Among 39 consecutive cases of acute subarachnoid hemorrhage (SAH), 33 were studied by three-dimensional computed tomographic angiography (CTA) within 6 h...

journal_title：Neurological research

authors： Nakajima Y,Yoshimine T,Mori H,Nakamuta K,Fujimura I,Sakashita K,Kohmura E,Hayakawa T,Yokota J

更新日期：2000-09-01 00:00:00

abstract：:We describe the technique of percutaneous carotid artery stent placement with distal protection in a patient in whom marked innominate artery ectasia prevented transfemoral access to the right common carotid artery. After induction of general anesthesia, ultrasound was used to guide direct puncture of the common carot...

journal_title：Neurological research

authors： Perez-Arjona EA,DelProsto Z,Fessler RD

更新日期：2004-04-01 00:00:00

abstract：INTRODUCTION:Cerebrospinal fluid (CSF) oligoclonal bands (OB) imply intrathecal immunoglobulin synthesis and B-cell immune process. There is scarce evidence of OB having a role in disease prognosis. The objective of the present study was to determine OB's prognostic value regarding disease progression. METHODS:Betwee...

journal_title：Neurological research

authors： Rojas JI,Tizio S,Patrucco L,Cristiano E

更新日期：2012-11-01 00:00:00

abstract：:In order to investigate the functional role of endothelium and vasoeffector mechanism in cerebrovascular responses to neuropeptides, the stainless steel cannula inserting method was applied to examine the responses to intraluminally-applied bradykinin, substance P and vasopressin in isolated and perfused canine basila...

journal_title：Neurological research

authors： Tsuji T,Cook DA

更新日期：1995-06-01 00:00:00

abstract：:We studied brain temperature and the effect of mild hypothermia in 58 patients after severe head injury (SHI). Brain tissue oxygen tension (ptiO2), carbon dioxide tension (ptiCO2), tissuie pH (pHti) and temperature (T.br) were measured using a multiparameter probe. Microdialysis was performed to measure glucose, lacta...

journal_title：Neurological research

authors： Soukup J,Zauner A,Doppenberg EM,Menzel M,Gilman C,Bullock R,Young HF

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Natalizumab is a drug with documented efficacy in relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of natalizumab has immunosuppressive properties and it is not yet investigated if treatment with natalizumab affects the immunological response to vaccination. This study aims to investig...

journal_title：Neurological research

authors： Vågberg M,Kumlin U,Svenningsson A

更新日期：2012-09-01 00:00:00

abstract：:In this study the pulsation-pressure relationship in an experimental model of aneurysms was analyzed. In addition, we have examined pulsatility of the aneurysmal wall reinforced by Guglielmi Detachable Coils (GDC). Bifurcation (BAn), aneurysms (LAn) and bilobar (BiA) aneurysms were produced in 15 mongrel dogs. The ane...

journal_title：Neurological research

authors： Novak P,Glikstein R,Mohr G

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:To explore the risk factors for stroke-associated pneumonia (SAP). METHODS:A retrospective research study was carried out to investigate the clinical data of 1435 patients admitted to the neurological intensive care unit at our university hospital between 1 January 2000 and 31 December 2009. RESULTS:A multi...

journal_title：Neurological research

authors： Sui R,Zhang L

更新日期：2011-06-01 00:00:00

abstract：:Single-cell experiments were undertaken to characterize the neurons of the rat habenular complex (Hab) which respond to noxious input and the extent to which the noxious responses can be modulated by dorsal raphe stimulation. The reported observations demonstrate that habenular neurons exhibit two response patterns to...

journal_title：Neurological research

authors： Dafny N,Qiao JT

更新日期：1990-06-01 00:00:00

abstract：:Predictions from a structured cortical model led us to test the hypothesis that music training enhances young children's spatial-temporal reasoning. Seventy-eight preschool children participated in this study. Thirty-four children received private piano keyboard lessons, 20 children received private computer lessons, ...

journal_title：Neurological research

authors： Rauscher FH,Shaw GL,Levine LJ,Wright EL,Dennis WR,Newcomb RL

更新日期：1997-02-01 00:00:00

abstract：INTRODUCTION:Here, we investigated inflammatory signs of peripheral nerves in leptin-deficient obese ob/ob mice and the modulating effects of the exogenous iron load. METHODS:Ob/ob and ob/+ control mice were fed with high, standard, or low iron diet for four months. RESULTS:We found intraepidermal nerve fiber degener...

journal_title：Neurological research

authors： Kosacka J,Woidt K,Toyka KV,Paeschke S,Klöting N,Bechmann I,Blüher M,Thiery J,Ossmann S,Baum P,Nowicki M

更新日期：2019-04-01 00:00:00

abstract：:The correlation between the activities of anti-GQ1b IgG antibodies in sera of patients with Miller Fisher syndrome and their clinical manifestations was investigated. The clinical severity was analyzed for 16 patients by scoring their symptoms during the peak of the clinical course and 4 weeks after onset. Serum sampl...

journal_title：Neurological research

authors： Mizoguchi K

更新日期：1998-10-01 00:00:00

abstract：:We currently have used three drugs in combination [mannitol, vitamin E and glucocorticoid (beta-methasone)] for the treatment of cerebral infarction in the acute stage. For the purpose of evaluating the efficacy of this therapy, we have conducted experiments evaluated by chemiluminescence (CL), energy metabolism and w...

journal_title：Neurological research

authors： Uenohara H,Imaizumi S,Suzuki J,Yoshimoto T

更新日期：1988-06-01 00:00:00

abstract：:The purpose of this prospective observational study was to investigate the relation between the frequency of critical neuromonitoring parameters (brain tissue pO2, (PtiO2) < or = 10 mmHg, intracranial pressure (ICP) > 20 mmHg, cerebral perfusion pressure (CPP) < or = 70 mmHg) and outcome after severe aneurysmal subara...

journal_title：Neurological research

authors： Meixensberger J,Vath A,Jaeger M,Kunze E,Dings J,Roosen K

更新日期：2003-07-01 00:00:00

abstract：:The goal of this paper is to provide scientists with a comprehensive review of the state-of-the-art influence the ischemic blood-brain barrier (BBB) has on the final development of Alzheimer's disease and to provide detailed food-for-thought which will hopefully stimulate more researchers in this area of neuroscience....

journal_title：Neurological research

authors： Pluta R

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hypothermia has shown promise as a neuroprotective strategy for stroke. The use of whole body hypothermia has limited clinical utility due to many severe side effects. Selective brain cooling, or local brain hypothermia, has been previously proposed as an alternative treatment strategy. This st...

journal_title：Neurological research

authors： Wang B,Wu D,Dornbos Iii D,Shi J,Ma Y,Zhang M,Liu Y,Chen J,Ding Y,Luo Y,Ji X

更新日期：2016-06-01 00:00:00

abstract：:Although neuronal death has been studied in experimental models of ischemia, the precise mechanisms regulating cell death remain unclear. Furthermore, the timing and pattern of neuronal death in human stroke has not been extensively studied. To further our understanding of ischemia-induced neuronal death, we examined ...

journal_title：Neurological research

authors： Guglielmo MA,Chan PT,Cortez S,Stopa EG,McMillan P,Johanson CE,Epstein M,Doberstein CE

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:Equestrian sports can result in a variety of injuries to the nervous system due to many factors. We describe our series of 80 patients with injuries sustained during participation in equestrian sports. METHODS AND RESULTS:All patients seen at the regional trauma center with injuries associated with equestri...

journal_title：Neurological research

authors： Srinivasan V,Pierre C,Plog B,Srinivasan K,Petraglia AL,Huang JH

更新日期：2014-10-01 00:00:00

abstract：:The authors have done a revision of 450 patients admitted during the last 3 years to the emergency service of the Hospital de S. José with the diagnosis of CVA. In this retrospective study were included the patients of greater than or equal to 3 degree of the RLS/85 coma scale, the diagnostic being confirmed by CAT, a...

journal_title：Neurological research

authors： Costa B,Candido J,Girbal A,Afonso L,Ribeiro J,Gonçalves V,Luis V,Antunes J

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...

journal_title：Neurological research

authors： DeGracia DJ,Kreipke CW,Kayali FM,Rafols JA

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To assess the clinical significance of hepatitis B virus (HBV) infection in patients with cerebral venous sinus thrombosis (CVST). METHODS:Twenty-two patients with CVST confirmed by magnetic resonance venography (MRV) or digital subtraction angiography (DSA) and 743 controls with ischemic stroke confirmed by...

journal_title：Neurological research

authors： Shan F,Gao C,Long Y,Huang L,Zheng Y,Chen M,Fan Y,Yin J

更新日期：2015-06-01 00:00:00

abstract：:The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the...

journal_title：Neurological research

authors： Tanaka R,Miyasaka Y,Maruyama S,Nagai S,Fujii K

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVES:The present study investigated the effects of tetrahydrobiopterin (BH4) on cerebral infarction after transient focal ischemia in rats. METHODS:Focal ischemia (1·5 hours) was created in male Sprague-Dawley rats (250-280 g) by middle cerebral artery occlusion. Some rats were treated with 20 mg/kg tetrahydrob...

journal_title：Neurological research

authors： Tang LL,Zheng JS

更新日期：2011-12-01 00:00:00

abstract：:A new and reproducible saccular aneurysm model has been developed at the bifurcation of the common carotid artery in rats. The details of the experimental methods and results are described. It is strongly suggested that the internal elastic lamina is a critical layer in saccular aneurysm formation, because an experime...

journal_title：Neurological research

authors： van Alphen HA,Gao YZ,Kamphorst W

更新日期：1990-12-01 00:00:00

abstract：:It is known that mitochondrial ATP-sensitive potassium channels (mitoKATP) play a significant role in protecting cerebral function from ischemia-reperfusion injury, which is related with a decrease in the mitochondrial matrix calcium. However, the effect of mitochondrial calcium uniporter (MCU) on diazoxide-induced ce...

journal_title：Neurological research

authors： Zhang L,Wang S,Dong H,Li Y,Wang P,Li S,Guo Y,Yao R

更新日期：2014-07-01 00:00:00

abstract：:The successful treatment of an intracranial arteriovenous malformation poses both technical and conceptual problems to the neurosurgeon. Treatment decisions are made in light of current understanding of the natural history of these lesions. It is important to understand the pros, cons and current indication of open cr...

journal_title：Neurological research

authors： Surdell DL Jr,Bhattacharjee S,Loftus CM

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...

journal_title：Neurological research

authors： Berntsen EM,Samuelsen P,Lagopoulos J,Rasmussen IA Jr,Håberg AK,Haraldseth O

更新日期：2008-11-01 00:00:00