Abstract:
:The authors have done a revision of 450 patients admitted during the last 3 years to the emergency service of the Hospital de S. José with the diagnosis of CVA. In this retrospective study were included the patients of greater than or equal to 3 degree of the RLS/85 coma scale, the diagnostic being confirmed by CAT, angiography and/or autopsy, and simultaneously evaluated by the Glasgow coma scale. The studied population was grouped into: SAH; ICH with or without ventricular drowning, cerebellar haematoma, brainstem haematoma, ischaemic CVA. The factors of vascular risk: diabetes and hypertension, the age of the patients and coma level were correlated with the degree of cerebral disability of discharge in all patients. The following factors are clearly related with bad prognosis: coma of degree greater than or equal to 4 in the RLS/85 scale; ischaemic aetiology; intraventricular haemorrhage.
journal_name
Neurol Resjournal_title
Neurological researchauthors
Costa B,Candido J,Girbal A,Afonso L,Ribeiro J,Gonçalves V,Luis V,Antunes Jdoi
10.1080/01616412.1992.11740023subject
Has Abstractpub_date
1992-01-01 00:00:00pages
100-2issue
2 Suppleissn
0161-6412issn
1743-1328journal_volume
14pub_type
杂志文章abstract:OBJECTIVE:To review past, present and future applications of near-infrared spectroscopy (NIRS) in clinical neuroscience. METHODS:The literature and personal experience of the authors were critically reviewed in order to provide a balanced overview of the basic principles, clinical validation, previous experience and c...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/174313209X383286
更新日期:2009-07-01 00:00:00
abstract::A mathematical model, using differential equations, of heterosynaptic plasticity is proposed. The model is based on physiological studies of invertebrates in which nonspecific conditioning, such as sensitization and heterosynaptic inhibition, starts to be elucidated and behavioral studies of classical and instrumental...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1980.11739576
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313208X325191
更新日期:2009-02-01 00:00:00
abstract::This investigation was designed to clarify the chronic effects of cardiogenic emboli on cerebral perfusion and tissue densities within remaining noninfarcted brain. Local cerebral perfusion and tissue densities were measured by xenon-contrasted CT scanning and compared by cross-sectional designs among normal volunteer...
journal_title:Neurological research
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system. A contribution from complement has long been suspected. We investigated the association of complement factor H (CFH) Tyr402 His gene polymorphism and serum level in Egyptian patients with MS to examine whet...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132815Y.0000000075
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker that is associated with the outcomes of ischemic stroke. However, the role of hs-CRP levels in the functional outcomes after large-artery atherosclerosis (LAA) and small-artery occlusion (SAO) is poorly understood. METHODS:We recruited 1...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2017.1358937
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To investigate risk factors for neurological complications after off-pump coronary artery bypass grafting (OPCABG). METHODS:We reviewed the cases of 813 patients who underwent OPCABG between August 2010 and September 2013.Data from preoperative 320 dynamic volume computed tomography (CT), CT angiography (CTA...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132815Y.0000000030
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:Patent foramen ovale (PFO) is considered as an important risk factor for cerebrovascular diseases. Nevertheless, the relationship between the distribution of high-intensity transient signals (HITS), resulting from injection of air mixed with saline and detected by transcranial Doppler (TCD), and clinical cer...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X18458
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:The role of inflammation in cognitive alterations in a post-operative setting is still not fully understood. Surgical interventions can cause systemic inflammations which eventually can induce neuroinflammation. However, the main causes of functional changes after surgery are still elusive. In this study, we ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.2016.1242452
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated. ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X385617
更新日期:2009-11-01 00:00:00
abstract::Rats were exposed in utero plus 60 days post-partum to either complex music (Mozart Sonata (k. 448)), minimalist music (a Philip Glass composition), white noise or silence, and were then tested for five days, three trials per day, in a multiple T-maze. By Day 3, the rats exposed to the Mozart work completed the maze m...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1998.11740543
更新日期:1998-07-01 00:00:00
abstract::Alzheimer disease (AD), a central nervous system degenerative disease, is characterized by abnormal deposition of amyloid-β peptide (Aβ), neurofibrillary tangles formed by hyperphosphorylated tau and synaptic loss. It is widely accepted that Aβ is the chief culprit of AD. Aβ peptide is the cleavage product of amyloid-...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1080/01616412.2015.1133485
更新日期:2016-02-01 00:00:00
abstract::Excessive entry of Ca2+ into injured cochlear neurons activates various Ca(2+)-activated enzymes and subsequent spiral ganglion cell death. Therefore, preventing intracellular calcium overload by using Ca2+ channel antagonists may become an important countermeasure to spiral ganglion cell death. We experimentally inve...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164102101200889
更新日期:2002-12-01 00:00:00
abstract::The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1997.11740795
更新日期:1997-04-01 00:00:00
abstract::The aim of this study was to use quantitative microdialysis to estimate the true extracellular concentrations of glucose and lactate in minimally disturbed human brain. These values are important as criteria for microdialytical monitoring in critical care patients and for determining therapy. Microdialysis procedures ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164101101198785
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Crossed-uncrossed differentials (CUDs) are viewed as surrogates for interhemispheric transfer time (IHTT). Not uncommonly CUDs assume statistically significant negative values (inverted CUDs). This raises doubts of the accepted interpretation of CUDs, i.e. intra- and inter-hemispheric routings of signals in ...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164106X115107
更新日期:2006-10-01 00:00:00
abstract::Monitoring of brain tissue oxygenation (ptiO2) enables early diagnosis of secondary cerebral ischemia and may guide a cerebral perfusion pressure (CPP) orientated therapy. The purpose of our study was to explain the concept of ptiO2-autoregulation, defined as the ability of the brain to maintain ptiO2 despite changes ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164103101201580
更新日期:2003-06-01 00:00:00
abstract::The role of intra-operative pathological diagnosis increases along with a development of minimally invasive neurosurgery, especially stereotactic and endoscopic techniques. The authors present their own experience with the cytological method and evaluate its usefulness in intra-operative diagnosis of brain tumors. Bra...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1080/01616412.1999.11740907
更新日期:1999-01-01 00:00:00
abstract::Cyclic GMP (cGMP) mediates smooth muscle relaxation in the central nervous system. In subarachnoid hemorrhage (SAH), decreases in intrinsic nitric oxide (NO) cause cerebral vasospasms due to the regulation of cGMP formation by NO-mediated pathways. As phosphodiesterase type V (PDE V) selectively hydrolyzes cGMP, we hy...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164102101200447
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:The presence of beta-amyloid (betaA) deposition, induction of reactive gliosis and dystrophic neurites, is a characteristic feature of neuritic plaques in Alzheimer's disease. In vitro, betaA-exposed astrocytes become reactive, similar to astrocytes in contact with betaA plaques in vivo. How betaA-exposed re...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164105X40020
更新日期:2005-07-01 00:00:00
abstract::Decreased metabolic rate may precede cognitive impairment in Alzheimer's disease (AD) and is thus an early occurring hallmark. Several observations in post-mortem brain indicate that activated neurons are better able to withstand aging and AD, a phenomenon paraphrased by us as 'use it or lose it'. Moreover, a number o...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164103101201959
更新日期:2003-09-01 00:00:00
abstract::Experiments were carried out to clarify the effect of serotonin [5-hydroxytryptamine (5-HT)] upon the somatosensory evoked potential (SEP) elicited by superficial radial nerve stimulation in cat, and the following results were obtained: (i) in untreated (control) animals, a significant reduction occurred in amplitude ...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1989.11739871
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:Giant and large intracranial aneurysms represent enormous therapeutic challenges for neurosurgeons as well as for endovascular therapists. Since they may involve entire vessels or be irregular in shape, the rate of complete obliteration with GDCs is low and the incidence of recanalization is very high. So th...
journal_title:Neurological research
pub_type: 临床试验,杂志文章
doi:10.1179/174313208X319017
更新日期:2008-07-01 00:00:00
abstract::Congenital dural arteriovenous fistulas have been infrequently described in pediatric population and they generally affect the transverse, sigmoid, straight or sagittal sinuses. Congenital carotid-cavernous fistulas in infancy are considered very rare and to our knowledge, only four cases have been reported in literat...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313208X291612
更新日期:2008-07-01 00:00:00
abstract::This study was designed to evaluate the effects of two consecutive ischaemias on extracellular monoaminergic neurotransmitter concentrations. The data on the neuroamine changes induced by the second ischaemia could be used to assess the delay in aminergic neurotransmission subsequent to the primary injury. Dopamine (D...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1993.11740134
更新日期:1993-06-01 00:00:00
abstract::The survival of a group of patients with malignant gliomas of the brain submitted to radical surgery and radiotherapy was studied. The average survival was nearly 4 times longer with X-ray treatment than with cobalt 60 irradiation when a comparison was made between 24 patients with glioblasto-astroblastoma (grade 3-4)...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1080/01616412.1987.11739796
更新日期:1987-09-01 00:00:00
abstract::The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and a...
journal_title:Neurological research
pub_type: 杂志文章,评审
doi:10.1179/016164107X240198
更新日期:2007-10-01 00:00:00
abstract::In this work, we evaluated the differences between epileptic electroencephalogram (EEG) and interictal EEG by computing some non-linear features. Correlation dimension (CD) and Hurst exponent (H) were calculated for 100 segments of epileptic EEG and 100 segments of interictal EEG. A comparison was made between epilept...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/1743132811Y.0000000041
更新日期:2011-11-01 00:00:00
abstract::OBJECTIVE: To explore the neural substrates of implicit self-esteem in university students. METHODS: The subjects comprised four females and six males (aged 20-25 years). They were asked to finish the implicit association test (IAT) for implicit self-esteem while brain electrical activity was recorded at 64 scalp site...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/174313209X431138
更新日期:2009-07-08 00:00:00
abstract:OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...
journal_title:Neurological research
pub_type: 杂志文章
doi:10.1179/016164107X204666
更新日期:2007-06-01 00:00:00