Biomathematical models of schizophrenia.

abstract：:The present study was designed to investigate the beneficial effects of cornel iridoid glycoside (CIG), a main component extract from Cornus officinalis, on neurotrophin expression in mouse experimental autoimmune encephalomyelitis (EAE), a classical model of multiple sclerosis (MS). After EAE initiation, CIG was intr...

journal_title：Neurological research

authors： Qu Z,Zheng N,Zhang Y,Zhang L,Liu J,Wang Q,Yin L

更新日期：2016-09-01 00:00:00

abstract：:Excessive entry of Ca2+ into injured cochlear neurons activates various Ca(2+)-activated enzymes and subsequent spiral ganglion cell death. Therefore, preventing intracellular calcium overload by using Ca2+ channel antagonists may become an important countermeasure to spiral ganglion cell death. We experimentally inve...

journal_title：Neurological research

authors： Sekiya T,Yagihashi A,Asano K,Suzuki S

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:Natalizumab is a drug with documented efficacy in relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of natalizumab has immunosuppressive properties and it is not yet investigated if treatment with natalizumab affects the immunological response to vaccination. This study aims to investig...

journal_title：Neurological research

authors： Vågberg M,Kumlin U,Svenningsson A

更新日期：2012-09-01 00:00:00

abstract：:Objectives: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). Methods: Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.5 h, 6...

journal_title：Neurological research

authors： Hao CH,Ding WX,Sun Q,Li XX,Wang WT,Zhao ZY,Tang LD

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:Cerebral hypoxia-ischemia leads to the depletion of ATP. Hypoxanthine, a degradation product of ATP, can be salvaged by hypoxanthine phosphoribosyl transferase (HPRT) and used to reform high-energy purines. Hypothermia conserves ATP in hypoxia-ischemia, possibly by preserving HPRT activity. We hypothesized t...

journal_title：Neurological research

authors： Cherin T,Catbagan M,Treiman S,Mink R

更新日期：2006-12-01 00:00:00

abstract：:Background The distribution of risk factors for stroke is related to gender and age. The main objective of study was to determine the type and frequency of stroke risk factors in patients with first-in-life stroke before the age of 50. Methods Our study included patients under the age of 50 with first-in-life stroke. ...

journal_title：Neurological research

authors： Lasek-Bal A,Kopyta I,Warsz-Wianecka A,Puz P,Łabuz-Roszak B,Zaręba K

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:It has been suggested that metalloproteinase-9 (MMP-9) could predict the onset of cerebral vasospasm after subarachnoidal haemorrhage (SAH). The aim of this study was to analyse, in patients with SAH, the difference between patients with MRI ischaemic infarcts and patients without, and to investigate the rol...

journal_title：Neurological research

authors： Lago A,Tembl JI,López-Cuevas R,Vallés J,Santos MT,Moscardó A,Parkhutik V

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:We attempted to determine whether a functional polymorphism of TRPM6 (rs2274924) is associated with susceptibility to epilepsy following ischemic stroke, and to further explore the effect of this polymorphism on serum levels of Mg2+ in post-stroke patients. METHODS:We carried out a case-control study on 378...

journal_title：Neurological research

authors： Fu CY,Chen SJ,Cai NH,Liu ZH,Zhang M,Wang PC,Zhao JN

更新日期：2019-04-01 00:00:00

abstract：:The objective of this study was to determine, whether 0.5-2/min oscillations in intracranial pressure ('B-waves') are a physiological phenomenon. In a group of 5 patients 0.5-2/min oscillations of ventricular pressure simultaneous with oscillations in the middle cerebral artery (MCA) flow velocity, as assessed by tran...

journal_title：Neurological research

authors： Mautner-Huppert D,Haberl RL,Dirnagl U,Villringer A,Schmiedek P,Einhäupl K

更新日期：1989-12-01 00:00:00

abstract：:The anatomical substrates of the perception of motion have not yet been established in a detailed way on an individual level. The aim of this study was to develop a systematic procedure for mapping the visual cortex using Transcranial Magnetic Stimulation (TMS). The results showed that such an individual and detailed ...

journal_title：Neurological research

authors： d'Alfonso AA,van Honk J,Schutter DJ,Caffé AR,Postma A,de Haan EH

更新日期：2002-04-01 00:00:00

abstract：:This study comprises scientific-theoretic fundamental investigations of laserneedle technology, a new and painless method of acupuncture stimulation. Laserneedles are not inserted in the skin, but are merely placed on the surface of the acupuncture point. The study documents the significant changes in peripheral micro...

journal_title：Neurological research

authors： Litscher G

更新日期：2003-10-01 00:00:00

abstract：:The effects of long-term administration of fructose-added glycerol solution (Glyceol): 10% glycerol, 5% fructose, 0.9% sodium chloride; 600-2000 ml/d intravenously for 7-63 d) were evaluated in a multi-institutional trial involving 1346 cases. Improvement of the neurological signs and symptoms of elevated intracranial...

journal_title：Neurological research

authors： Tsubokawa T,Katayama Y,Ishii S

更新日期：1989-12-01 00:00:00

abstract：:The craniocervical regions of seven cadavers (14 sides) injected with silicone rubber were dissected under a Zeiss OPMI surgical microscope. The present study provides a detailed description of the suboccipital segment of the vertebral artery, with particular attention to its loops, branches, supporting osteofibrous s...

journal_title：Neurological research

authors： Castillo C,Viñas FC,Gutikhonda M,Diaz FG

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:Chronic subdural hematoma (cSDH) has an increasing incidence and results in high morbidity and mortality. We review here the 10-year experience of a single institution and the literature regarding the treatment and major associations of cSDH. METHODS:We retrospectively reviewed all cSDHs surgically treated f...

journal_title：Neurological research

authors： Balser D,Rodgers SD,Johnson B,Shi C,Tabak E,Samadani U

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:The study objectives are (1) to identify factors predicting the excellent visual recovery after transsphenoidal removal of pituitary tumors and (2) to describe the association of excellent visual recovery and early restoration of symmetry of the decompressed optic chiasm. METHODS:Thirty-five patients with v...

journal_title：Neurological research

authors： Yoneoka Y,Hatase T,Watanabe N,Jinguji S,Okada M,Takagi M,Fujii Y

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:The syntheses of endothelin receptors A and B were previously shown to be upregulated in rat dorsal hippocampus after traumatic brain injury. Here we characterize endothelin receptor A and endothelin receptor B cellular distribution in hippocampus after permanent global brain ischemia and their possible asso...

journal_title：Neurological research

authors： Kreipke CW,Reynolds CA,Schafer PC,Schafer S,Pirooz R,Rafols JA

更新日期：2011-03-01 00:00:00

abstract：:Treatment modalities for metastatic spine disease have significantly expanded over the last two decades. This expansion occurred in many different fields. Improvement in surgical techniques and instrumentation now allow the oncologic spine surgeons to effectively circumferentially decompress the neural elements withou...

journal_title：Neurological research

authors： Dea N,Fisher CG

更新日期：2014-06-01 00:00:00

abstract：:It has been established that following injury to the central nervous system two types of damage take place, the initial insult and the secondary response to injury. This review will focus on the secondary molecular aspects of neurotrauma. These responses may be either deleterious or have protective effects upon the in...

journal_title：Neurological research

authors： Dutcher SA,Michael DB

更新日期：2001-03-01 00:00:00

abstract：:A mathematical model, using differential equations, of heterosynaptic plasticity is proposed. The model is based on physiological studies of invertebrates in which nonspecific conditioning, such as sensitization and heterosynaptic inhibition, starts to be elucidated and behavioral studies of classical and instrumental...

journal_title：Neurological research

authors： Lara R,Tapia R,Cervantes F,Moreno A,Trujillo H

更新日期：1980-01-01 00:00:00

abstract：:Sixty-five years old patient suffering from acute stroke was treated by rTPA intravenously. TCD monitoring of both middle cerebral arteries (MCA) was carried out simultaneously with administration of rTPA. Seven microemboli were found in right and four in left MCA. Duplex ultrasound, CT angiography and digital subtrac...

journal_title：Neurological research

authors： Telman G,Kouperberg E,Eran A,Goldsher D,Yarnitsky D

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...

journal_title：Neurological research

authors： Berntsen EM,Samuelsen P,Lagopoulos J,Rasmussen IA Jr,Håberg AK,Haraldseth O

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:The unified Parkinson's disease rating scale (UPDRS) is the most widely used tool to rate the severity and the stage of Parkinson's disease (PD). However, the mentation, behavior and mood (MBM) subscale of the UPDRS has received little investigation regarding its validity and sensitivity. Three items of this ...

journal_title：Neurological research

authors： Holroyd S,Currie LJ,Wooten GF

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study is to use diffusion tensor imaging (DTI) parameters to evaluate cerebral ischemia/reperfusion injury in the infarct core (IC) and ischemic penumbra (IP) in a rhesus transient middle cerebral artery occlusion (MCAO) model. METHODS:Seven rhesus monkeys were used to construct the MCAO...

journal_title：Neurological research

authors： Guo J,Zheng HB,Duan JC,He L,Chen N,Gong QY,Tang HH,Li HX,Wang L,Cheng JQ

更新日期：2011-01-01 00:00:00

abstract：:The object of the study was to evaluate brain tissue oxygenation (p(ti)O2) for intra-operative monitoring of critical ischemic events during early cerebral aneurysm surgery of the anterior circulation supplementary to somatosensory evoked potentials (SEPs). P(ti)O2 was continuously evaluated during surgery for an intr...

journal_title：Neurological research

authors： Szelényi A,Jung CS,Schön H,Seifert V

更新日期：2002-09-01 00:00:00

abstract：:Previous work has shown that unsaturated fatty acid components of model membrane phospholipids in vitro, damaged via a free radical mechanism, are protected by the presence of cholesterol in these membranes. The participation of these membrane lipids in the pathogenesis of traumatic injury to brain was studied in vivo...

journal_title：Neurological research

authors： Mitamura JA,Seligman ML,Solomon JJ,Flamm ES,Demopoulos HB,Ransohoff J

更新日期：1981-01-01 00:00:00

abstract：:Monitoring of regional cerebral oxygen saturation (r. cereb. O2 satn.) was carried out continuously in 12 healthy subjects (mean age 35.2 +/- 4.4 years; range 26-41 years; 4 women, 8 men), prior to, during and following acupuncture. Measurements were obtained with the INVOS 3100 cerebral oximeter (Somanetics Corp., Tr...

journal_title：Neurological research

authors： Litscher G,Schwarz G,Sandner-Kiesling A,Hadolt I,Eger E

更新日期：1998-01-01 00:00:00

abstract：:[15O]-water PET was performed on 12 patients with structural lesions for localization of the motor (n = 5), language (receptive and expressive; n = 6), and visual cortex (n = 1). All these patients underwent interactive image-guided surgery using an infrared digitizer and intraoperative electrical stimulation mapping ...

journal_title：Neurological research

authors： Viñas FC,Zamorano L,Mueller RA,Jiang Z,Chugani H,Fuerst D,Muzik O,Mangner TJ,Diaz FG

更新日期：1997-12-01 00:00:00

abstract：:Brain tumours were induced by intracerebral inoculation of beagle puppies with Avian sarcoma virus (ASV) suspension. The inoculation produced solitary or multiple sarcomas in three dogs and intraventricular anaplastic gliomas in four dogs. At the time of the first tumour positive CT-control Iodine-125 seeds (activity ...

journal_title：Neurological research

authors： Ostertag CB,Warnke P,Kleihues P,Bigner DD

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVES:In the present study, we investigated the effects of treadmill exercise on microglial activation and the subsequent release of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6 and IL-1-beta in the hippocampus in a rat model of type 2 diabetes. METHODS:At 30 weeks of age, diabetic (Zucker diabeti...

journal_title：Neurological research

authors： Yoo DY,Chae J,Jung HY,Yim HS,Kim JW,Nam SM,Kim DW,Choi JH,Seong JK,Yoon YS,Hwang IK

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:The feasibility of high resolution CT imaging for evaluating experimentally-induced brain tumors in rats was assessed. METHODS:The gliosarcoma cell line (9 L/lacZ) was inoculated in 34 male Fischer 344 rats and CT studies were performed prior to and at 4, 7, 9, 12 and 14 days post-tumor cell implantation. Br...

journal_title：Neurological research

authors： Psarros TG,Mickey B,Giller C

更新日期：2005-01-01 00:00:00