Combination therapy with U74006F (tirilazad mesylate), MK-801, insulin and diazepam in transient forebrain ischaemia.

abstract：OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...

journal_title：Neurological research

authors： Berntsen EM,Samuelsen P,Lagopoulos J,Rasmussen IA Jr,Håberg AK,Haraldseth O

更新日期：2008-11-01 00:00:00

abstract：:Objective Preoperative magnetic resonance (MR) angiography sometimes shows the absence of collateral flow via the circle of Willis. This study examined whether brain temperature (BT) imaging on multi-voxel proton MR spectroscopy after this finding increases the accuracy of predicting hemispheric ischemia during intern...

journal_title：Neurological research

authors： Tsutsui S,Nanba T,Yoshioka Y,Sasaki M,Fujiwara S,Kobayashi M,Yoshida K,Miyoshi K,Sato S,Ogasawara K

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To explore clinical features and compare of the difference between conservative treatment and surgical treatmentin prognosis of intracranial aneurysms associated with moyamoya disease (MMD). METHODS:104 patients with MMD a ssociated with intracranial aneurysms diagnosed by digital subtraction angiography (D...

journal_title：Neurological research

authors： Yan J,Lv M,Zeng E,Tang B,Xie S,Hong T

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:To review the use of immunoassays in the diagnosis and research of disorders affecting the nervous system. METHODS:Systematic review of the English literature. RESULTS:Immunoassays have demonstrated utility for: (1) the detection of antigen (molecules, genes, gene products, peptides, hormones and drug meta...

journal_title：Neurological research

authors： Meriggioli MN

更新日期：2005-10-01 00:00:00

abstract：:We describe the technique of percutaneous carotid artery stent placement with distal protection in a patient in whom marked innominate artery ectasia prevented transfemoral access to the right common carotid artery. After induction of general anesthesia, ultrasound was used to guide direct puncture of the common carot...

journal_title：Neurological research

authors： Perez-Arjona EA,DelProsto Z,Fessler RD

更新日期：2004-04-01 00:00:00

abstract：:The role of intra-operative pathological diagnosis increases along with a development of minimally invasive neurosurgery, especially stereotactic and endoscopic techniques. The authors present their own experience with the cytological method and evaluate its usefulness in intra-operative diagnosis of brain tumors. Bra...

journal_title：Neurological research

authors： Slowiński J,Harabin-Slowińska M,Mrówka R

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:The feasibility of high resolution CT imaging for evaluating experimentally-induced brain tumors in rats was assessed. METHODS:The gliosarcoma cell line (9 L/lacZ) was inoculated in 34 male Fischer 344 rats and CT studies were performed prior to and at 4, 7, 9, 12 and 14 days post-tumor cell implantation. Br...

journal_title：Neurological research

authors： Psarros TG,Mickey B,Giller C

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:We attempted to determine whether a functional polymorphism of TRPM6 (rs2274924) is associated with susceptibility to epilepsy following ischemic stroke, and to further explore the effect of this polymorphism on serum levels of Mg2+ in post-stroke patients. METHODS:We carried out a case-control study on 378...

journal_title：Neurological research

authors： Fu CY,Chen SJ,Cai NH,Liu ZH,Zhang M,Wang PC,Zhao JN

更新日期：2019-04-01 00:00:00

abstract：:We describe a novel approach for analysing the hemodynamic alterations that result after focal cerebral ischemia. This approach utilizes a temporal correlation analysis of first pass transit data obtained with functional imaging. First pass transits of injected contrast agents are measured with dynamic CT scanning. No...

journal_title：Neurological research

authors： Lo EH,Rogowska J,Batchelder KF,Wolf GL

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:Music-supported therapy (MST) is a new approach for motor rehabilitation of stroke patients. Recently, many studies have demonstrated that MST improved the motor functions of post-stroke patients. However, the underlying mechanism for this effect is still unclear. It may result from repeated practice or repea...

journal_title：Neurological research

authors： Tong Y,Forreider B,Sun X,Geng X,Zhang W,Du H,Zhang T,Ding Y

更新日期：2015-05-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, whose relentless course leads to death within 2-5 years, generally due to respiratory failure. Apart from the age and site of onset, no other factors have consistently demonstrated to be related to the ALS outc...

journal_title：Neurological research

authors： Dedic SI,Stevic Z,Dedic V,Stojanovic VR,Milicev M,Lavrnic D

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:The study objectives are (1) to identify factors predicting the excellent visual recovery after transsphenoidal removal of pituitary tumors and (2) to describe the association of excellent visual recovery and early restoration of symmetry of the decompressed optic chiasm. METHODS:Thirty-five patients with v...

journal_title：Neurological research

authors： Yoneoka Y,Hatase T,Watanabe N,Jinguji S,Okada M,Takagi M,Fujii Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system. A contribution from complement has long been suspected. We investigated the association of complement factor H (CFH) Tyr402 His gene polymorphism and serum level in Egyptian patients with MS to examine whet...

journal_title：Neurological research

authors： Abdel Rasol HA,Helmy H,Aziz MA

更新日期：2015-10-01 00:00:00

abstract：:The elements of peripheral nerve regeneration comprise a complex combination of nerve growth, muscle satellite cells proliferation and differentiation and vessel growth. There is also increasing evidence that growth factors may act at multiple levels in the regenerative response. One such factor affecting multiple cel...

journal_title：Neurological research

authors： Rabinovsky ED

更新日期：2004-03-01 00:00:00

abstract：:Analysis of the blood flow velocities in the middle cerebral artery by transcranial Doppler ultrasonography was performed in 158 healthy volunteers (aged 14-70 years; 82 men and 76 women). In a subgroup of 38 men and 21 women the end-tidal [CO2] was also measured. The influence of biological factors such as age, sex, ...

journal_title：Neurological research

authors： Ackerstaff RG,Keunen RW,van Pelt W,Montauban van Swijndregt AD,Stijnen T

更新日期：1990-09-01 00:00:00

abstract：:A 51-year-old man presented with loss of consciousness when he underwent urological examination at another hospital. CT scans showed subarachnoid hemorrhage, and cerebral angiography showed bilateral dissecting aneurysms of the vertebral arteries. Following ventricular drainage, the lesion was managed conservatively w...

journal_title：Neurological research

authors： Matsumoto K,Akagi K,Abekura M,Sakaguchi T

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:Amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer's disease (AD), but soluble oligomeric Aβ is considered to be more potent and has been hypothesized to directly impair learning and memory. Also, evidences from some clinical studies indicated that Aβ oligomer...

journal_title：Neurological research

authors： Sharma S,Verma S,Kapoor M,Saini A,Nehru B

更新日期：2016-09-01 00:00:00

abstract：:Our goal was to clarify the optimum management of the inaccessible unruptured giant and large aneurysms of the internal carotid artery (ICA). Since 1981, we have treated 18 patients with unclippable unruptured giant or large aneurysms of the ICA. Aneurysms were classified as either intracavernous or intradural. We per...

journal_title：Neurological research

authors： Kaminogo M,Kitagawa N,Takahata H,Matsuo Y,Hayashi K,Yoshioka T,Shibata S

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:After a spinal cord injury (SCI), most men experience fertility related problems including poor semen quality in which decreased sperm viability and motility, have been proposed to be related to the accessory sex glands dysfunction. In this study, we investigated the probable effects of SCI on the seminal ves...

journal_title：Neurological research

authors： Dashtdar H,Valojerdi MR

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:To find new biomarkers by stimulating acupuncture point GB34 (Yangneungcheon) which has neuroprotective effect on the mouse model of Parkinson's disease, analysis of cDNA microarray on mRNAs of the substantia nigra was performed. METHODS:Male C57BL/6 mice were divided into two groups: 1-methyl-4-phenyl-1,2,...

journal_title：Neurological research

authors： Hong MS,Park HK,Yang JS,Park HJ,Kim ST,Kim SN,Park JY,Song JY,Park HK,Jo DJ,Park SW,HwanYun D,Ban JY,Chung JH

更新日期：2010-02-01 00:00:00

abstract：:Intravenous infusion of glycerol has been used in patients with a cerebral infarction, expecting improvement in brain edema and cerebral blood flow (CBF). However, the mechanism of the improvement of CBF has not been clearly demonstrated. The aim of this study in the rat pial microvasculature after transient middle ce...

journal_title：Neurological research

authors： Ishikawa M,Sekizuka E,Sato S,Yamaguchi N,Inamasu J,Kawase T

更新日期：1999-12-01 00:00:00

abstract：:Background: Surgery of parasagittal meningiomas (PSMs) is still technically challenging, for the balance between radical resection and preservation of venous circulation. In this article, we'd systemically introduce the technical nuances of a simplified strategy for radical resection of all types of PSMs. All the case...

journal_title：Neurological research

authors： Zhang N,Yang T,Hameed F,Zhang X,Yao Y,Li D,Li C,Yu S,Xu Y,Xia C,Fu X

更新日期：2020-11-11 00:00:00

abstract：:This article covers the basis of tethered cord syndrome as a stretch-induced spinal cord disorder, including pathophysiology, signs and symptoms, imaging diagnosis, indication for surgical treatment, and surgical procedures. Anomalies that cause mechanical spinal cord tethering are listed, and the surgical untethering...

journal_title：Neurological research

authors： Yamada S,Won DJ,Siddiqi J,Yamada SM

更新日期：2004-10-01 00:00:00

abstract：:Anesthesia is an essential element during the induction of ischemia/reperfusion and cerebral blood flow (CBF) measurement in most animal models. Cerebral neuroprotection and intrinsic effects on CBF afforded by anesthetics are confounding variables in those models. A new model of global forebrain ischemia/reperfusion ...

journal_title：Neurological research

authors： Melgar MA,Park H,Rafols JA,Diaz FG

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Tissue plasminogen activator (tPA) may aggravate ischemic neuronal damage after focal cerebral ischemia and increase blood-brain barrier permeability. Human serum albumin has neuroprotective effects on ischemic stroke. However, whether albumin can attenuate the deleterious effects of tPA is yet unknown. METH...

journal_title：Neurological research

authors： Tang J,Li YJ,Mu J,Li Q,Yang DY,Xie P

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:Although magnesium is a well-known treatment for vasospasm following subarachnoid hemorrhage, its mechanism of action for cerebral vascular relaxation is not clear. In addition, it is known that L-type calcium (Ca(2+)) channels play a pivotal role in smooth muscle contraction. To investigate the role of L-t...

journal_title：Neurological research

authors： Sharma N,Cho DH,Kim SY,Bhattarai JP,Hwang PH,Han SK

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:The amyloid hypothesis stimulates the discovery of compounds, which promotes beta-amyloid peptide (Aβ) clearance, thereby altering the underlying pathophysiology of Alzheimer's disease (AD). Hence, the present study aims at the evaluation of anti-amyloidogenic potential of Gelidiella acerosa. METHODS:Prevent...

journal_title：Neurological research

authors： Syad AN,Devi KP

更新日期：2015-01-01 00:00:00

abstract：:Somatosensory-evoked potentials induced by electrical stimulation of the median nerve were recorded in patients with intracerebral lesions and in normal controls and were studied by means of spectral analysis. The results shown that (1) there is a statistically-significant difference between spectral distributions obt...

journal_title：Neurological research

authors： Kusske JA,Romiti JA,Porter RW,Verzeano M

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:Computed tomographic angiography (CTA) was invented more than 20 years ago, but only gained acceptance recently, thanks to advancements in the computer technology. It can demonstrate areas of arterial stenosis or occlusion with accuracy nearly that of digital subtraction angiography (DSA). It is also able to ...

journal_title：Neurological research

authors： Zubkov AY,Uschmann H,Rabinstein AA

更新日期：2008-10-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) possesses neuroprotective effects on a variety of neurons. Here we report that it delays progression of motor neuron disease (MND) in the wobbler mouse. After initial diagnosis of MND at post-natal age 3-4 weeks, wobbler mice receive either recombinant human bFGF (1 mg kg-1, n = 1...

journal_title：Neurological research

authors： Ikeda K,Iwasaki Y,Tagaya N,Shiojima T,Kobayashi T,Kinoshita M

更新日期：1995-12-01 00:00:00