Use of immunoassays in neurological diagnosis and research.

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：:The aim of this study was to examine the pre-operative clinical and neuromonitoring courses in patients with a decompressive craniectomy to assess and to compare clinical and neuromonitoring signs indicating extensive cerebral edema. We conducted a retrospective analysis of the clinical signs and courses of simultaneo...

journal_title：Neurological research

authors： Strege RJ,Lang EW,Stark AM,Scheffner H,Fritsch MJ,Barth H,Mehdorn HM

更新日期：2003-07-01 00:00:00

abstract：:The normal cerebral circulation has the ability to maintain a stable cerebral blood flow over a wide range of cerebral perfusion pressures and this is known as cerebral autoregulation. This autoregulation may be impaired in the injured brain. Closed head injury was induced in 28 Sprague-Dawley rats weighing 400-450 g....

journal_title：Neurological research

authors： Prat R,Markiv V,Dujovny M,Misra M

更新日期：1997-08-01 00:00:00

abstract：:HEADTOME III, a high resolution PET, has been employed using 15O and 18F labelled pharmaceuticals to evaluate histological malignancy of gliomas preoperatively. PET study was applied on eighteen preoperative gliomas including two recurrent cases. Haemocirculatory and metabolic indices of regional cerebral blood flow (...

journal_title：Neurological research

authors： Mineura K,Yasuda T,Kowada M,Shishido F,Ogawa T,Uemura K

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:It has been suggested that metalloproteinase-9 (MMP-9) could predict the onset of cerebral vasospasm after subarachnoidal haemorrhage (SAH). The aim of this study was to analyse, in patients with SAH, the difference between patients with MRI ischaemic infarcts and patients without, and to investigate the rol...

journal_title：Neurological research

authors： Lago A,Tembl JI,López-Cuevas R,Vallés J,Santos MT,Moscardó A,Parkhutik V

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Natalizumab is a drug with documented efficacy in relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of natalizumab has immunosuppressive properties and it is not yet investigated if treatment with natalizumab affects the immunological response to vaccination. This study aims to investig...

journal_title：Neurological research

authors： Vågberg M,Kumlin U,Svenningsson A

更新日期：2012-09-01 00:00:00

abstract：:No marker that predicts accurately the time of occurrence of cerebral vasospasm due to subarachnoid hemorrhage (SAH) has been reported. In the present study, membrane-bound tissue factor (mTF) and myelin basic protein (MBP) concentrations in cerebrospinal fluid (CSF) were evaluated as a predictor of the time of occurr...

journal_title：Neurological research

authors： Hirashima Y,Endo S,Nakamura S,Kurimoto M,Takaku A

更新日期：2001-10-01 00:00:00

abstract：:The goal of this paper is to provide scientists with a comprehensive review of the state-of-the-art influence the ischemic blood-brain barrier (BBB) has on the final development of Alzheimer's disease and to provide detailed food-for-thought which will hopefully stimulate more researchers in this area of neuroscience....

journal_title：Neurological research

authors： Pluta R

更新日期：2006-09-01 00:00:00

abstract：:We investigated the neuroprotective effects of a novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor (pitavastatin) on ischemic neuronal damage in gerbils using immunohistochemistry. The animals were allowed to survive for 14 days after 5 min of ischemia induced by bilateral occlusion of the comm...

journal_title：Neurological research

authors： Kurosaki R,Muramatsu Y,Kato H,Araki T

更新日期：2004-09-01 00:00:00

abstract：:Advances in neuromodulation techniques offer the promise of new therapeutic interventions for patients with neuropsychiatric maladies. Several complex social, ethical and policy issues will attend developments in this area. In this paper an ethical framework for clinical research in interventional cognitive neuroscien...

journal_title：Neurological research

authors： Fins JJ

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:Tissue plasminogen activator (tPA) may aggravate ischemic neuronal damage after focal cerebral ischemia and increase blood-brain barrier permeability. Human serum albumin has neuroprotective effects on ischemic stroke. However, whether albumin can attenuate the deleterious effects of tPA is yet unknown. METH...

journal_title：Neurological research

authors： Tang J,Li YJ,Mu J,Li Q,Yang DY,Xie P

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the characteristics of atherosclerotic middle cerebral artery (MCA) stenosis by high-resolution magnetic resonance imaging (HR-MRI) and determine the relationship between wall characteristics and infarction patterns. METHODS:Thirty-six patients with acute ischaemic stroke due to MCA stenosis unde...

journal_title：Neurological research

authors： Zhao DL,Deng G,Xie B,Gao B,Peng CY,Nie F,Yang M,Ju S,Teng GJ

更新日期：2016-07-01 00:00:00

abstract：:Recovery of motor function following stroke is believed to be supported, at least in part, by functional compensation involving residual neural tissue. The present study used a rodent model of focal ischemia and intracortical microstimulation (ICMS) to examine the behavioral and physiological effects of cortical stimu...

journal_title：Neurological research

authors： Kleim JA,Bruneau R,VandenBerg P,MacDonald E,Mulrooney R,Pocock D

更新日期：2003-12-01 00:00:00

abstract：:The frequency of skull metastasis from hepatocellular carcinoma (HCC) is increasing together with the recent progress in the management of the primary lesion. Cases are often complicated with poor general conditions or metastasis to the other organs, and not readily indicated for surgery. A direct injection of ethanol...

journal_title：Neurological research

authors： Isaka T,Yoshimine T,Fujimoto K,Masuzawa M,Maruno M,Hayakawa T,Nakatani S

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:The present study characterized glial cell injury provoked in adult rat chiasm within 24 hours after a single, high-dose irradiation of 20 Gy. METHODS:All chiasmal glial cells in a section were counted, and the percentage of TUNEL-positive glial cells exhibiting apoptotic morphology was defined as the apopt...

journal_title：Neurological research

authors： Nagayama K,Kurita H,Nakamura M,Kusuda J,Tonari A,Takayama M,Fujioka Y,Shiokawa Y

更新日期：2005-06-01 00:00:00

abstract：:Nerve growth factor (NGF) synthesis in cultured mouse L-M fibroblast and astroglial cells can be increased after the treatment with L-threo-3,4-dihydroxyphenylserine (DOPS). Since the increase of NGF is not blocked by the treatment with decarboxylase inhibitor, DOPS may have direct effect to increase the NGF content. ...

journal_title：Neurological research

authors： Lee TH,Abe K,Nakamura M,Kogure K,Itoyama Y

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the effects of the GLP-1 analog liraglutide on beta-amyloid (Aβ)-induced neurotoxicity in the human neuroblastoma cell line SH-SY5Y and study the underlying mechanisms. METHODS:Cultured SH-SY5Y cells in vitro were randomly divided into normal control group, beta-amylo...

journal_title：Neurological research

authors： Liu XY,Wang LX,Chen Z,Liu LB

更新日期：2016-04-01 00:00:00

abstract：:This article covers the basis of tethered cord syndrome as a stretch-induced spinal cord disorder, including pathophysiology, signs and symptoms, imaging diagnosis, indication for surgical treatment, and surgical procedures. Anomalies that cause mechanical spinal cord tethering are listed, and the surgical untethering...

journal_title：Neurological research

authors： Yamada S,Won DJ,Siddiqi J,Yamada SM

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND/AIMS:Both of neuromyelitis optica spectrum disease (NMOSDs) and idiopathic transverse myelitis (ITM) could present as acute transverse myelitis. However, long-term immunological treatment and prognosis are different for high recurrence of NMOSDs. In this study, we summarized clinical differences between acut...

journal_title：Neurological research

authors： Liu Z,Xie M,Lu Z,Zhang C,Chen H,Xu Y,Zhang M

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Membrane disruption is one of the main factors that cause axonal damage and functional deficits manifested in spinal cord injury (SCI). In this study, we used polyethylene glycol (PEG) to induce immediate membrane sealing and to promote functional recovery after SCI. METHODS:The effects of PEG (200-2000 Da)...

journal_title：Neurological research

authors： Kouhzaei S,Rad I,Mousavidoust S,Mobasheri H

更新日期：2013-05-01 00:00:00

abstract：:Excessive entry of Ca2+ into injured cochlear neurons activates various Ca(2+)-activated enzymes and subsequent spiral ganglion cell death. Therefore, preventing intracellular calcium overload by using Ca2+ channel antagonists may become an important countermeasure to spiral ganglion cell death. We experimentally inve...

journal_title：Neurological research

authors： Sekiya T,Yagihashi A,Asano K,Suzuki S

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...

journal_title：Neurological research

authors： DeGracia DJ,Kreipke CW,Kayali FM,Rafols JA

更新日期：2007-06-01 00:00:00

abstract：:We examined whether or not NF-kappaB, a factor that regulates expression of the genes that code for pro-inflammatory cytokines, is activated in cerebrospinal fluid (CSF) cells to investigate the production of pro-inflammatory cytokines by CSF cells in patients with meningitis. Western blotting demonstrated that NF-kap...

journal_title：Neurological research

authors： Ichiyama T,Isumi H,Yoshitomi T,Nishikawa M,Matsubara T,Furukawa S

更新日期：2002-10-01 00:00:00

abstract：:We have reliable data on the degree of stenosis above which endarterectomy for symptomatic carotid stenosis is beneficial, but benefit is also influenced by other factors, particularly age, sex, the timing of surgery, plaque surface morphology and the nature of the presenting symptomatic event(s). This review will con...

journal_title：Neurological research

authors： Rothwell PM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...

journal_title：Neurological research

authors： Ramírez-Zamora A,Alarcón T

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is a major risk factor for stroke and all of its pathological subtypes including subarachnoid hemorrhage (SAH). However, there is little evidence demonstrating whether failure to have regular BP measured could result in underestimation of people at risk for SAH. Therefore, we aimed ...

journal_title：Neurological research

authors： Shiue I,Hankey GJ,Arima H,Anderson CS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Misery perfusion increases the risk of stroke recurrence in patients with symptomatic major cerebral artery occlusion. The ratio of brain perfusion contralateral-to-affected asymmetry in the cerebellar hemisphere to brain perfusion affected-to-contralateral asymmetry in the cerebral hemisphere ...

journal_title：Neurological research

authors： Nomura J,Ogasawara K,Saito H,Terasaki K,Matsumoto Y,Takahashi Y,Ogasawara Y,Saura H,Yoshida K,Sato Y,Kubo Y,Ogawa A

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To assess the effect of sensory nerve stimulation in older people with peripheral neuropathy associated with diabetes (DPN). MATERIALS AND METHODS:A randomized, placebo controlled, double blind trial was used to assess the effect of 12 weeks of low frequency sensory nerve stimulation (LF-SNS) in the lower li...

journal_title：Neurological research

authors： Khalil Z,Ogrin R,Darzins PJ

更新日期：2007-10-01 00:00:00

abstract：:A 51-year-old man presented with loss of consciousness when he underwent urological examination at another hospital. CT scans showed subarachnoid hemorrhage, and cerebral angiography showed bilateral dissecting aneurysms of the vertebral arteries. Following ventricular drainage, the lesion was managed conservatively w...

journal_title：Neurological research

authors： Matsumoto K,Akagi K,Abekura M,Sakaguchi T

更新日期：2002-12-01 00:00:00

abstract：:Intravenous infusion of glycerol has been used in patients with a cerebral infarction, expecting improvement in brain edema and cerebral blood flow (CBF). However, the mechanism of the improvement of CBF has not been clearly demonstrated. The aim of this study in the rat pial microvasculature after transient middle ce...

journal_title：Neurological research

authors： Ishikawa M,Sekizuka E,Sato S,Yamaguchi N,Inamasu J,Kawase T

更新日期：1999-12-01 00:00:00