Simultaneous recording of tissue PCO2, interstitial pH and potassium activity in the rat cerebral cortex during anoxia and the subsequent recovery period.

abstract：:Nerve growth factor (NGF) synthesis in cultured mouse L-M fibroblast and astroglial cells can be increased after the treatment with L-threo-3,4-dihydroxyphenylserine (DOPS). Since the increase of NGF is not blocked by the treatment with decarboxylase inhibitor, DOPS may have direct effect to increase the NGF content. ...

journal_title：Neurological research

authors： Lee TH,Abe K,Nakamura M,Kogure K,Itoyama Y

更新日期：1994-06-01 00:00:00

abstract：:We describe the technique of percutaneous carotid artery stent placement with distal protection in a patient in whom marked innominate artery ectasia prevented transfemoral access to the right common carotid artery. After induction of general anesthesia, ultrasound was used to guide direct puncture of the common carot...

journal_title：Neurological research

authors： Perez-Arjona EA,DelProsto Z,Fessler RD

更新日期：2004-04-01 00:00:00

abstract：:Vestibular neuritis (VN) rapidly damages unilateral vestibular periphery, inducing severe balance disorders. In most cases, such vestibular imbalance is gradually restored to within the normal level after clinical therapies. This successive clinical recovery occurs due to regeneration of vestibular periphery and/or ac...

journal_title：Neurological research

authors： Kitahara T,Kondoh K,Morihana T,Okumura S,Horii A,Takeda N,Kubo T

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:In order to avoid occurrence of post-operative hygromas in specific hydrocephalus patients being at high risk of overdrainage, a combination of programmable valve and anti-gravity device is widely recommended. We analyzed our series of hydrocephalus patients implanted with such a shunt configuration focusin...

journal_title：Neurological research

authors： Zachenhofer I,Donat M,Roessler K

更新日期：2012-04-01 00:00:00

abstract：INTRODUCTION:Cocaine- and amphetamine-regulated transcript (CART) peptide has been demonstrated to exert neuroprotective effects in stroke and some neurodegeneration diseases. In current study, we investigated the protective effects and underlying mechanisms of CART in APP/PS1 mice. METHODS:The protein levels of CART,...

journal_title：Neurological research

authors： Yin K,Jin J,Zhu X,Yu L,Wang S,Qian L,Han L,Xu Y

更新日期：2017-10-01 00:00:00

abstract：:Objectives: Neurovascular compression syndromes (NVCS) could be cured with an intravascular device that releases compression of the root entry zone of cranial nerves by changing the course of offending vessels. The purpose of this study was to report our results of in vitro and in vivo experiments with a novel intra-a...

journal_title：Neurological research

authors： Chun Y,Chen Y,Elsisy M,Sukinik J,Shridhar P,Park JK,Kim YB,Hong CK,Chung J

更新日期：2019-07-01 00:00:00

abstract：:This paper presents the results of transsphenoidal surgery in 41 consecutive patients with visual loss from pituitary adenomas. The most common pattern of loss was bitemporal hemianopia. Transsphenoidal decompression resulted in visual improvement in 78% of patients. If patients with optic atrophy and pre-operative co...

journal_title：Neurological research

authors： el-Azouzi M,Black PM,Candia G,Zervas NT,Panagopoulos KP

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is a multi-factorial disease influenced by both genetic and environmental factors. The aim of this case-control study was to determine the association between Endothelial Nitric Oxide Synthase G894T (rs1799983) gene polymorphism and susceptibility to ischemic stroke (IS) in North Indian po...

journal_title：Neurological research

authors： Kumar A,Misra S,Kumar P,Sagar R,Prasad K,Pandit AK,Chakravarty K,Kathuria P,Yadav AK

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Membrane disruption is one of the main factors that cause axonal damage and functional deficits manifested in spinal cord injury (SCI). In this study, we used polyethylene glycol (PEG) to induce immediate membrane sealing and to promote functional recovery after SCI. METHODS:The effects of PEG (200-2000 Da)...

journal_title：Neurological research

authors： Kouhzaei S,Rad I,Mousavidoust S,Mobasheri H

更新日期：2013-05-01 00:00:00

abstract：: Objectives : To detect and compare the features of interictal perfusion and volume asymmetry between temporal lobe epilepsy (TLE) patients with and without hippocampal sclerosis (HS). Methods : Sixty-one TLE patients (mean age ...

journal_title：Neurological research

authors： Zhang Y,Dou W,Zuo Z,You H,Lv Y,Hou B,Shi L,Feng F

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVES:Natalizumab is a drug with documented efficacy in relapsing-remitting multiple sclerosis (RRMS). The mechanism of action of natalizumab has immunosuppressive properties and it is not yet investigated if treatment with natalizumab affects the immunological response to vaccination. This study aims to investig...

journal_title：Neurological research

authors： Vågberg M,Kumlin U,Svenningsson A

更新日期：2012-09-01 00:00:00

abstract：:The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...

journal_title：Neurological research

authors： Litscher G

更新日期：2001-12-01 00:00:00

abstract：:The influence of acidic fibroblast growth factor (aFGF) on sleep was studied in conscious rabbits. An intravenous (i.v.) bolus injection of aFGF induced a significant increase in sleep duration in comparison with animals that received vehicle solution. Somnogenic effects were obtained 30 min following i.v. aFGF admini...

journal_title：Neurological research

authors： Galan JM,Cuevas B,Dujovny N,Giménez-Gallego G,Cuevas P

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of electrical stimulation (ES), stretching and their combined effects in matrix metalloproteinases (MMPs) gene expression and activity during early denervation of rat tibialis anterior (TA) muscle by axonotmesis. METHODS:Thirty adult male Wistar rats were divided into five groups: no...

journal_title：Neurological research

authors： Peviani SM,Russo TL,Durigan JL,Vieira BS,Pinheiro CM,Galassi MS,Salvini TF

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:The novel coronavirus disease (COVID-19) pandemic poses a substantial threat to the health of healthcare personnel on the front line of caring for COVID-19 patients. The Centers for Medicare and Medicaid Services previously announced that all non-essential planned surgeries and procedures should be postpon...

journal_title：Neurological research

authors： Reed LK,Wen J,Liang B,Wang X,Feng D,Huang JH

更新日期：2020-10-01 00:00:00

abstract：:The elements of peripheral nerve regeneration comprise a complex combination of nerve growth, muscle satellite cells proliferation and differentiation and vessel growth. There is also increasing evidence that growth factors may act at multiple levels in the regenerative response. One such factor affecting multiple cel...

journal_title：Neurological research

authors： Rabinovsky ED

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:In conditions with reduced glucose levels/inability of glucose utilization, ketone bodies, especially beta-hydroxybutyrate (BHB), become a major energy source in the brain. In animal models, BHB infusion shows acute beneficial effects on the hypoxic brain. The present prospective observational study is the f...

journal_title：Neurological research

authors： Pikija S,Trkulja V,Simundic AM,Vrcek E,Boskovic K,Bacani S

更新日期：2013-11-01 00:00:00

abstract：:In order to investigate the role of the endothelium in the regulation of cerebrovascular tone, we studied selective intraluminal and extraluminal vasoactive mechanisms of acetylcholine, potassium and serotonin. We also examined the effects of removal of the endothelium on these vasoactive responses. With 0.75 g of ten...

journal_title：Neurological research

authors： Ogawa R,Ohta T,Tsuji M,Mori M

更新日期：1993-06-01 00:00:00

abstract：:Traumatic brain injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. Specific topics addressed in this paper include magnitude of the problem, causes, context of injury occurrence, risk factors, severity, outcome and impact of TBIs on...

journal_title：Neurological research

authors： Gururaj G

更新日期：2002-01-01 00:00:00

abstract：:The application of optical spectroscopy for intra-operatively delineating brain tumors has been studied in this paper. The classification of tissue as normal, tumor and boundary is done using the LAMSTAR neural network (NN). The objective is to combine both fluorescence and reflectance as attributes to be used for the...

journal_title：Neurological research

authors： Sivaramakrishnan A,Graupe D

更新日期：2004-09-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) possesses neuroprotective effects on a variety of neurons. Here we report that it delays progression of motor neuron disease (MND) in the wobbler mouse. After initial diagnosis of MND at post-natal age 3-4 weeks, wobbler mice receive either recombinant human bFGF (1 mg kg-1, n = 1...

journal_title：Neurological research

authors： Ikeda K,Iwasaki Y,Tagaya N,Shiojima T,Kobayashi T,Kinoshita M

更新日期：1995-12-01 00:00:00

abstract：OBJECT:The pathologies resulting from traumatic brain injury (TBI) have been thoroughly studied, but rarely have the effects of bleeding and coagulation in the early stage of TBI been considered. In this study, we investigated the effects of topical Surgiflo® application on brain injury in experimental TBI mice using S...

journal_title：Neurological research

authors： Guo D,Li D,Li J,Li Y,Hu X,Guan F,Yang B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Cerebral hypoxia-ischemia leads to the depletion of ATP. Hypoxanthine, a degradation product of ATP, can be salvaged by hypoxanthine phosphoribosyl transferase (HPRT) and used to reform high-energy purines. Hypothermia conserves ATP in hypoxia-ischemia, possibly by preserving HPRT activity. We hypothesized t...

journal_title：Neurological research

authors： Cherin T,Catbagan M,Treiman S,Mink R

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:The suppressor gene maspin (Serpin B5) is a promising candidate for future treatment. We have examined the messenger RNA (mRNA) and protein expression of maspin in normal breast tissue, breast cancer primaries, brain metastases and breast cancer cell lines. Results were compared to hormone receptor expressio...

journal_title：Neurological research

authors： Stark AM,Schem C,Maass N,Hugo HH,Jonat W,Mehdorn HM,Held-Feindt J

更新日期：2010-04-01 00:00:00

abstract：:The potential role of magnetic resonance angiography (MRA) in clinical neurosurgical practice was evaluated in 150 consecutive patients in an attempt to define clinical situations in which it aided in diagnosis, helped guide treatment options, and/or possibly eliminated the need for conventional catheter angiography. ...

journal_title：Neurological research

authors： Awad IA,Mckenzie R,Magdinec M,Masaryk T

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study is to use diffusion tensor imaging (DTI) parameters to evaluate cerebral ischemia/reperfusion injury in the infarct core (IC) and ischemic penumbra (IP) in a rhesus transient middle cerebral artery occlusion (MCAO) model. METHODS:Seven rhesus monkeys were used to construct the MCAO...

journal_title：Neurological research

authors： Guo J,Zheng HB,Duan JC,He L,Chen N,Gong QY,Tang HH,Li HX,Wang L,Cheng JQ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Mapping of brain perfusion using bolus tracking methods is increasingly used to assess the amount and severity of cerebral ischemia in acute stroke. Using relative perfusion maps, however, it is difficult to identify the tissue at risk-maximum (TARM) of infarction with sufficient reliability and reproducibil...

journal_title：Neurological research

authors： Nabavi DG,Dittrich R,Kloska SP,Nam EM,Klotz E,Heindel W,Ringelstein EB

更新日期：2007-04-01 00:00:00

abstract：:Neuronal nitric oxide synthase (nNOS) regulates neurogenesis in normal developing brain, but the role of nNOS in neurogenesis in the ischemic brain remains unclear. To investigate the temporal and spatial relationship between cell proliferation of the ependymal/subventricular zone (SVZ), a principal neuroproliferative...

journal_title：Neurological research

authors： Zhang P,Liu Y,Li J,Kang Q,Tian Y,Chen X,Shi Q,Song T

更新日期：2006-01-01 00:00:00

abstract：:We elected to compare the clinical outcomes of carotid endarterectomy (CEA) patients who were thought to be at increased risk for peri-operative complications because of advanced age (> 79 years), medical comorbidities and contralateral internal carotid artery occlusion to patients without these risk factors. A prospe...

journal_title：Neurological research

authors： Harbaugh RE,Magnadottir HB

更新日期：2002-01-01 00:00:00

abstract：:Excessive calcium influx has been implicated in the pathophysiology of ischemic cerebral damage. The effects of nimodipine, a calcium antagonist, on the Na(+)-K+/MG+2 ATPase activity, Ca+2/Mg+2 ATPase, lipid peroxidation, and early ultrastructural findings were examined at the acute stage of ischemia in the rat brain....

journal_title：Neurological research

authors： Ildan F,Göçer AI,Tuna M,Polat S,Kaya M,Isbir T,Cetinalp E

更新日期：2001-01-01 00:00:00