Current evidence of temozolomide and bevacizumab in treatment of gliomas.

abstract：OBJECTIVE:In order to test for mechanisms of whole brain radio therapy side effects and possible neuroprotective measures, a rodent model is desirable. In many models, a high single dose of 8-20 Gray (Gy) of whole brain irradiation is used. These experimental radiation protocols do not closely reflect the clinical situ...

journal_title：Neurological research

authors： Semmler A,Garbe S,Moskau S,Frisch C,Eter N,Schlegel U,Linnebank M

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Cerebral small vessel disease (CSVD) describes a syndrome of neuroimaging, pathological, and associated clinical features caused by small intracranial vascular lesions, which commonly coexists with large artery atherosclerosis (LAA) and has been identified as a major cause of motor impairment over time. In th...

journal_title：Neurological research

authors： Zhu H,Li Z,Lv J,Zhao R

更新日期：2018-05-01 00:00:00

abstract：:According to recent reports, malnutrition may be associated with a worse prognosis in stroke patients. The aim of this study was to determine the nutritional status of stroke patients and its impact on neurological and functional status of patients in the early post-stroke period. Our prospective study included a tota...

journal_title：Neurological research

authors： Wierzbicki K,Horyniecki M,Mamak D,Szopa M,Buchała J,Stawarz G,Florek S,Adamczyk-Sowa M

更新日期：2020-01-01 00:00:00

abstract：:A computer software program (Seapit) was developed for precise determination of intracranial targets identified by stereotactic computed tomography (CT). This program was added to the software of a GE 8800 CT scanner to perform the following operations: millimetre precise calculation and display of the rectilinear coo...

journal_title：Neurological research

authors： Lunsford LD,Listerud JA,Rowberg AH,Latchaw RE

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...

journal_title：Neurological research

authors： Ramírez-Zamora A,Alarcón T

更新日期：2010-04-01 00:00:00

abstract：:It is being increasingly suggested that the microcirculation, which is known to be in a large part responsible for maintaining an adequate and constant microenvironment for function of the central nervous system, functions as part of a neurovascular unit. The neurovascular unit includes neurons, astrocytes and element...

journal_title：Neurological research

authors： Takahashi M,Macdonald RL

更新日期：2004-12-01 00:00:00

abstract：:The elements of peripheral nerve regeneration comprise a complex combination of nerve growth, muscle satellite cells proliferation and differentiation and vessel growth. There is also increasing evidence that growth factors may act at multiple levels in the regenerative response. One such factor affecting multiple cel...

journal_title：Neurological research

authors： Rabinovsky ED

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:This study investigated the relationship between traumatic coagulopathy and severe brain swelling (SBS) during decompressive surgery to evacuate a supratentorial intradural mass lesion in patients with traumatic brain injury (TBI). METHODS:A retrospective study was conducted in 96 patients who consecutively ...

journal_title：Neurological research

authors： Wang K,Xue Y,Chen X,Zhou B,Lou M

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:Surgical resection of complex glomus vagale tumors can be complicated by extensive blood loss and might require surgical sacrifice of an encased internal carotid artery. METHODS:A young patient presented with mass effect from glomus valage tumor. Computerized tomography angiography showed an encased interna...

journal_title：Neurological research

authors： Alaraj A,Pytynia K,Carlson AP,Krishna PH,Charbel FT,Amin-Hanjani S,Aletich V

更新日期：2012-07-01 00:00:00

abstract：:Endolymphatic sac tumors are rare, low-grade adenocarcinomas of the petrous bone. These tumors are highly vascularized and surgical removal is often challenging. We present a staged endovascular-neurosurgical approach consisting of stent-assisted angioplasty of the petrous carotid, selective endovascular embolization ...

journal_title：Neurological research

authors： Cohen JE,Spektor S,Valarezo J,Fellig Y,Umansky F

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To explore the value of dynamically monitored levels of plasma prothrombin fragment(1+2) (F(1+2)) and D-dimer in the process of thrombolysis with urokinase. METHODS:Blood samples were collected at baseline and at hours 1, 2, 3, 6, 12, 24, 48, 72, and 96 after urokinase infusion finished. The levels of plasma...

journal_title：Neurological research

authors： Meng R,Ji X,Li B,Zhou J,Li W,Ding Y

更新日期：2009-05-01 00:00:00

abstract：:Supraventricular and ventricular tachyarrhythmia are established causes of syncope. We investigated the mean blood flow velocities (Vmean) of the middle cerebral arteries (MCA) during routine cardiac electrophysiologic studies in patients with supraventricular and ventricular tachyarrhythmias in order to evaluate the ...

journal_title：Neurological research

authors： Zunker P,Haase C,Borggrefe M,Georgiadis D,Georgiadis A,Ringelstein EB

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China. SUBJECTS AND METHODS:A cross-sectional study (across 19 urban outpatient clinics) on secondary stroke prevention measures w...

journal_title：Neurological research

authors： Wang Y,Wu D,Zhou Y,Zhao X,Wang C,Liu L,Liao X,Wang Y

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:The utility of apparent diffusion coefficient (ADC) values was evaluated for the differential diagnosis of ganglioglioma. METHODS:Ten consecutive patients, five men and five women, aged from 14 to 67 years, with histologically proven supratentorial gangliogliomas, underwent diffusion-weighted magnetic reson...

journal_title：Neurological research

authors： Kikuchi T,Kumabe T,Higano S,Watanabe M,Tominaga T

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The feasibility of high resolution CT imaging for evaluating experimentally-induced brain tumors in rats was assessed. METHODS:The gliosarcoma cell line (9 L/lacZ) was inoculated in 34 male Fischer 344 rats and CT studies were performed prior to and at 4, 7, 9, 12 and 14 days post-tumor cell implantation. Br...

journal_title：Neurological research

authors： Psarros TG,Mickey B,Giller C

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Ischemia/hypoxia (I/H) causes severe neonatal brain injury, such as periventricular leukomaracia and hypoxic/ischemic encephalopathy. Neural stem cell research could lead to a treatment for such disorders. In order to elucidate the dynamic changes in neural stem cells in the neonatal brain after I/H, we inve...

journal_title：Neurological research

authors： Iwai M,Ikeda T,Hayashi T,Sato K,Nagata T,Nagano I,Shoji M,Ikenoue T,Abe K

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:The present study was undertaken to evaluate whether resveratrol (RSV) modulates membrane lipid composition, as well as on ganglioside profile in ischemia/reperfusion injury. METHODS:Global cerebral ischemia was induced by four-vessel occlusion for 10 minutes. RSV (30 mg/kg) or vehicle was intraperitoneally...

journal_title：Neurological research

authors： Simão F,Matté A,Breier AC,Kreutz F,Trindade VM,Netto CA,Salbego CG

更新日期：2013-01-01 00:00:00

abstract：:We describe the advantages and clarify the technical key points of a microendoscopic, minimally invasive technique to the posterior surgical approach for cervical degenerative disease. The authors studied the microendoscopic posterior approach using the METRx system in both cadaver models and in clinical cases. This n...

journal_title：Neurological research

authors： Yuguchi T,Nishio M,Akiyama C,Ito M,Yoshimine T

更新日期：2003-01-01 00:00:00

abstract：:Intra-arterial thrombolysis and percutaneous angioplasty is feasible in patients with acute middle cerebral artery (MCA) occlusion limited to 6 hours post-ictus, but there are some limitations such as reocclusion or hemorrhagic complications. In this report, we describe a stent placement in the treatment of a refracto...

journal_title：Neurological research

authors： Ahn JY,Han IB,Chung SS,Chung YS,Kim SH,Yoon PH

更新日期：2006-12-01 00:00:00

abstract：:Thromboxane A2 (TXA2) is a proaggregatory vasoconstrictor that is synthesized and released during reperfusion of ischaemic brain. We administered a TXA2 receptor antagonist, SQ29,548, and a thromboxane A synthase inhibitor, 1-benzylimidazole (1-BI), to rats subjected to 30 min of reversible forebrain ischaemia. Cerebr...

journal_title：Neurological research

authors： Pettigrew LC,Hazle JD,Gutierrez G,Smith CD,Ogletree ML

更新日期：1992-09-01 00:00:00

abstract：:Although the circulation of cerebrospinal fluid enjoys an apparent simplicity, its underlying basis is amazingly complex. Many factors influence how CSF flows through the human central nervous system. In the presence of hydrocephalus and subsequent shunt placement, this system is further complicated. The challenge bef...

journal_title：Neurological research

authors： Magram G,Liakos AM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Diffusion-weighted imaging (DWI) abnormalities can frequently be detected after carotid endarterectomy (CEA) and carotid angioplasty with stent placement (CAS) of the carotid arteries. We looked for possible predictors for the development of DWI lesions during the intervention. METHODS:We investigated 41 pa...

journal_title：Neurological research

authors： Poppert H,Wolf O,Theiss W,Heider P,Hollweck R,Roettinger M,Sander D

更新日期：2006-07-01 00:00:00

abstract：:Cerebral hemorrhages are subject to a heavy short- and long-term case fatality. A study of prognostic factors and of relative survival based on the data of a population registry is of great value to study patients having a hematoma of all ages, irrespective of the method of care. We have listed 183 patients having a c...

journal_title：Neurological research

authors： el Chami B,Milan C,Giroud M,Sautreaux JL,Faivre J

更新日期：2000-12-01 00:00:00

abstract：:At present, no practical method exists for monitoring the progression and severity of cerebral oedema in a clinical setting on a continuous basis. In search for such a method, we investigated the electrical characteristics of cerebral tissue at microwave frequencies to quantify cerebral oedema. The dielectric constant...

journal_title：Neurological research

authors： Kramer GG,Cardoso ER,Shwedyk E

更新日期：1992-06-01 00:00:00

abstract：:Sixty-five years old patient suffering from acute stroke was treated by rTPA intravenously. TCD monitoring of both middle cerebral arteries (MCA) was carried out simultaneously with administration of rTPA. Seven microemboli were found in right and four in left MCA. Duplex ultrasound, CT angiography and digital subtrac...

journal_title：Neurological research

authors： Telman G,Kouperberg E,Eran A,Goldsher D,Yarnitsky D

更新日期：2008-09-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, whose relentless course leads to death within 2-5 years, generally due to respiratory failure. Apart from the age and site of onset, no other factors have consistently demonstrated to be related to the ALS outc...

journal_title：Neurological research

authors： Dedic SI,Stevic Z,Dedic V,Stojanovic VR,Milicev M,Lavrnic D

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:Intracranial aneurysms (IAs) of the posterior circulation (PC) rupture more frequently and their morbidity and mortality rates are higher compared to anterior circulation. Morphological parameters such as size ratio (SR), inflow angle and parent artery geometry are believed to contribute significantly in det...

journal_title：Neurological research

authors： Tykocki T,Nauman P,Dow Enko A

更新日期：2014-08-01 00:00:00

abstract：:The endothelial lining of blood vessels plays an important role in the control of arterial tone by releasing a number of vasoactive factors. Among these, nitric oxide (NO) or a NO containing moiety, some cyclooxygenase products such as prostacyclin (PGl2) and a still hypothetical hyperpolarizing factor may induce dila...

journal_title：Neurological research

authors： Mackert JL,Parsons AA,Wahl M,Schilling L

更新日期：1997-10-01 00:00:00

abstract：:No marker that predicts accurately the time of occurrence of cerebral vasospasm due to subarachnoid hemorrhage (SAH) has been reported. In the present study, membrane-bound tissue factor (mTF) and myelin basic protein (MBP) concentrations in cerebrospinal fluid (CSF) were evaluated as a predictor of the time of occurr...

journal_title：Neurological research

authors： Hirashima Y,Endo S,Nakamura S,Kurimoto M,Takaku A

更新日期：2001-10-01 00:00:00

abstract：INTRODUCTION:Numerous studies have demonstrated a protective effect of hyperbaric oxygen therapy in experimental ischemic brain injury, and many physiological and molecular mechanisms of hyperbaric oxygen therapy-related neuroprotection have been identified. METHODS:Review of articles pertaining to hyperbaric oxygen t...

journal_title：Neurological research

authors： Matchett GA,Martin RD,Zhang JH

更新日期：2009-03-01 00:00:00