abstract：BACKGROUND:Although a variety of risk factors of pneumonia after clipping or coiling of the aneurysm (post-operative pneumonia [POP]) in patients with aneurysmal subarachnoid hemorrhage (aSAH) have been studied, the predictive model of POP after aSAH has still not been well established. Thus, the aim of this study was ...

journal_title：Chinese medical journal

authors： Chen Y,Lian BQ,Peng L,Ding CY,Lin YX,Yu LH,Wang DL,Kang DZ

更新日期：2020-12-24 00:00:00

abstract：:Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational leve...

journal_title：Chinese medical journal

authors： Song JK,Yin SY,Li W,Li XD,Luo Y,Luo Y,Xing M,Li B,Kuai L

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:The optimal surgical approach for four-level cervical spondylotic myelopathy remains controversial. The purpose of this study was to compare clinical and radiological outcomes and complications between the anterior and posterior approaches for four-level cervical spondylotic myelopathy. METHODS:A total of 1...

journal_title：Chinese medical journal

authors： Zhai JL,Guo SG,Nie L,Hu JH

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...

journal_title：Chinese medical journal

authors： Wen JN,Li N,Guo CX,Shen N,He B

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Studies have reported that low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)-infected patients; however, the factors that contribute to HIV-related BMD changes are yet to be fully understood. Due to the application of dual X-ray absorptiometry (DXA) among a select group of hos...

journal_title：Chinese medical journal

authors： Zeng YQ,Xiao J,Li CL,Wang Y,Zhang L,Pang XL,Wang D,Du J,Zhao HX

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Patients with temporal lobe epilepsy (TLE) originating from different seizure onset zones had distinct electrophysiological characteristics and surgical outcomes. In this study, we aimed to investigate the relationship between the origin and prognosis of TLE, and the stereoelectroencephalography (SEEG) featu...

journal_title：Chinese medical journal

authors： Yan XM,Xu CP,Wang YP,Ma K,Yu T,Zhang XH,Zhang X,Gao RS,Zhang GJ,Li YJ

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:The reverse obliquity inter-trochanteric fracture is a distinct fracture pattern that is mechanically different from most inter-trochanteric fractures and the optional treatment of it is still controversial. The purpose of this study was to compare differences in the efficacy of a novel nail (medial support ...

journal_title：Chinese medical journal

authors： Nie SB,Zhao YP,Li JT,Zhao Z,Zhang Z,Zhang LC,Tang PF

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Although breast-conserving surgery is one of the standard treatments for breast cancer, few studies have assessed its recent implementation in China. We aimed to clarify the current real-world status of breast-conserving surgery in China. METHODS:This cross-sectional survey relied on data collected by the C...

journal_title：Chinese medical journal

authors： Yu LX,Shi P,Tian XS,Yu ZG,Chinese Society of Breast Surgery.

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Epithelial to mesenchymal transition (EMT) is strongly linked with tumor invasion and metastasis, which performs a vital role in carcinogenesis and cancer progression. Emerging evidence suggests that microRNAs (miRNAs) expression are closely associated to EMT by regulating targeted genes. MiR542 has been fou...

journal_title：Chinese medical journal

authors： Li C,Liu HL,Zhou YM,Shi YC,Zhang ZB,Chen L,Feng SY

更新日期：2020-10-20 00:00:00

abstract：ABSTRACT:Cerebral small vessel disease (SVD) is a common global brain disease that causes cognitive impairment, ischemic or hemorrhagic stroke, problems with mobility, and neuropsychiatric symptoms. The brain damage, seen as focal white and deep grey matter lesions on brain magnetic resonance imaging (MRI) or computed ...

journal_title：Chinese medical journal

authors： Clancy U,Appleton JP,Arteaga C,Doubal FN,Bath PM,Wardlaw JM

更新日期：2020-10-06 00:00:00

abstract：:This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including "ELA," "ELA and neonatal outcomes," "ELA and children's development," and "ELA and children's neurocognitive development" were used t...

journal_title：Chinese medical journal

authors： Liu ZH,Wang DX

更新日期：2020-10-05 00:00:00

abstract：:Increasing numbers of targeted drugs are used in hormone receptor (HR)-positive metastatic breast cancer (MBC) to overcome or delay resistance to endocrine therapy. This study will systemically review the progress made in endocrine therapy combined with targeted therapy in the treatment of HR-positive MBC. From the "A...

journal_title：Chinese medical journal

authors： Bian L,Xu FR,Jiang ZF

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:Coronary atherosclerotic plaque could go through rapid progression and induce adverse cardiac events. This study aimed to evaluate the impacts of smoking status on clinical outcomes of coronary non-target lesions. METHODS:Consecutive patients with coronary heart disease who underwent two serial coronary ang...

journal_title：Chinese medical journal

authors： Xu HB,Wang J,Chen JL,Guo C,Yuan JS,Duan X,Hu FH,Yang WX,Luo XL,Liu R,Cui JG,Liu SW,Gao XJ,Chun YS,Qiao SB

更新日期：2020-10-05 00:00:00

abstract：:Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. The heart is one of the most important oxygen delivery organs, and dysfunction significantly increases the mortality of the body. Hence, the heart has been studied in sepsis for over half a century. However, th...

journal_title：Chinese medical journal

authors： Wang J,Wang XT,Liu DW,Zhang HM,Su LX

更新日期：2020-09-20 00:00:00

abstract：BACKGROUND:The effects of oral contrast agents (OCAs) on dosimetry have not been studied in detail. Therefore, this study aimed to examine the influence of OCAs on dose calculation in volumetric-modulated arc therapy plans for rectal cancer. METHODS:From 2008 to 2016, computed tomography (CT) images were obtained from...

journal_title：Chinese medical journal

authors： Jing H,Tian Y,Tang Y,Wang SL,Jin J,Song YW,Liu YP,Fang H,Chen B,Qi SN,Tang Y,Lu NN,Yang Y,Li N,Li YX

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：:Type 2 diabetes mellitus and metabolic disorders have become an epidemic globally. However, the pathogenesis remains largely unclear and the prevention and treatment are still limited. In addition to environmental factors during adulthood, early life is the critical developmental window with high tissue plasticity, wh...

journal_title：Chinese medical journal

authors： Zhou LY,Deng MQ,Zhang Q,Xiao XH

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Vascular endothelial dysfunction is considered a key pathophysiologic process for the development of acute lung injury. In this study, we aimed at investigating the effects of unfractionated heparin (UFH) on the lipopolysaccharide (LPS)-induced changes of vascular endothelial-cadherin (VE-cadherin) and the p...

journal_title：Chinese medical journal

authors： Mu ST,Tang J,Ma JQ,Zhong Y,Liu HZ,Ma XC,Zheng Z

更新日期：2020-08-05 00:00:00

abstract：:Endometriosis is a prevalent chronic disease that affects approximately 6% to 10% of reproductive-aged women. Although numerous researchers have endeavored to explore the etiology of endometriosis over a century, its etiology still remains an enigma. The exploration of pathophysiologic mechanism and novel therapy for ...

journal_title：Chinese medical journal

authors： Gu ZY,Jia SZ,Leng JH

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:The 2019 novel coronavirus has caused the outbreak of the acute respiratory disease in Wuhan, Hubei Province of China since December 2019. This study was performed to analyze the clinical characteristics of patients who succumbed to and who recovered from 2019 novel coronavirus disease (COVID-19). METHODS:C...

journal_title：Chinese medical journal

authors： Deng Y,Liu W,Liu K,Fang YY,Shang J,Zhou L,Wang K,Leng F,Wei S,Chen L,Liu HG

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Human epididymis secretory protein 4 (HE4) is a new ovarian cancer biomarker. The factors influencing HE4 levels are not clear, and the reference data in China are limited. Here, we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chi...

journal_title：Chinese medical journal

authors： Cheng HY,Zeng L,Ye X,Ma RQ,Tang ZJ,Chu HL,Zhao YM,Zhu LR,Gao YN,Chang XH,Cui H

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Atrial natriuretic peptide (ANP) and its natriuretic peptide receptors A (NPR-A) and C (NPR-C) are involved in the regulation of physiological and pathophysiological process of blood pressure. The present study aimed to determine the role of NPR-C in the development of salt-sensitive hypertension. METHODS:T...

journal_title：Chinese medical journal

authors： Zhu XL,Zhang T,Xu ZQ,Ma XC,Wang ZJ,Zou CW,Li JX,Jing HY

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Since early December 2019, the 2019 novel coronavirus disease (COVID-19) has caused pneumonia epidemic in Wuhan, Hubei province of China. This study aimed to investigate the factors affecting the progression of pneumonia in COVID-19 patients. Associated results will be used to evaluate the prognosis and to f...

journal_title：Chinese medical journal

authors： Liu W,Tao ZW,Wang L,Yuan ML,Liu K,Zhou L,Wei S,Deng Y,Liu J,Liu HG,Yang M,Hu Y

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Hyperuricemia and gout have become public health concerns; many important guidelines have recommended xanthine oxidase inhibitors (XOIs) as the first-line urate-lowering therapies (ULTs) to treat chronic gout with hyperuricemia. However, whether treating hyperuricemia and gout with ULTs modifies cardiovascul...

journal_title：Chinese medical journal

authors： Zhao L,Cao L,Zhao TY,Yang X,Zhu XX,Zou HJ,Wan WG,Xue Y

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most globally prevalent cancers in the world. The pathogenesis of GC has not been fully elucidated, and there still lacks effective targeted therapeutics. The influence of altered kinesin superfamily protein 22 (KIF22) expression in GC progression is still unclearly. The aim...

journal_title：Chinese medical journal

authors： Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:Various experimental and clinical studies have reported on coronary microcirculatory dysfunction ("no-reflow" phenomenon). Nevertheless, pathogenesis and effective treatment are yet to be fully elucidated. This study aimed to measure the intracoronary pressure gradient in the no-reflow artery during emergent...

journal_title：Chinese medical journal

authors： Gao MD,Zhang EY,Liu YY,Li XW,Xiao JY,Sun GY,Liu Y

更新日期：2020-04-05 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：:Enhanced recovery after cesarean (ERAC) delivery is an evidence-based, multi-disciplinary approach throughout pre-, intra-, post-operative period. The ultimate goal of ERAC is to enhance recovery and improve the maternal and neonatal outcomes. This review highlights the role of anesthesiologist in ERAC protocols. This...

journal_title：Chinese medical journal

authors： Liu ZQ,Du WJ,Yao SL

更新日期：2020-03-05 00:00:00

abstract：BACKGROUND:Although the use of expanded-criteria donors (ECDs) alleviates the problem of organ shortage, it significantly increases the incidence of delayed graft function (DGF). DGF is a common complication after kidney transplantation; however, the effect of DGF on graft loss is uncertain based on the published liter...

journal_title：Chinese medical journal

authors： Han F,Lin MZ,Zhou HL,Li H,Sun QP,Huang ZY,Hong LQ,Wang G,Cai RM,Sun QQ

更新日期：2020-03-05 00:00:00

abstract：BACKGROUND:Pioglitazone may be beneficial in the treatment of psoriasis. However, based on the effectiveness and safety considerations, it has not been widely used. To fully evaluate the strength of evidence supporting psoriasis treatment with pioglitazone, we conducted a meta-analysis of existing published studies. M...

journal_title：Chinese medical journal

authors： Zhang JZ,Ding Y,Xiang F,Yu SR,Zhang DZ,Guan MM,Kang XJ

更新日期：2020-02-20 00:00:00

abstract：:Diabetes mellitus and pancreatic ductal adenocarcinoma are two common diseases worldwidely which are both derived from different components of pancreas. The pancreatic and duodenal homeobox-1 (PDX1) is an essential transcription factor for the early development of pancreas that is required for the differentiation of a...

journal_title：Chinese medical journal

authors： Tang ZC,Chu Y,Tan YY,Li J,Gao S

更新日期：2020-02-05 00:00:00

abstract：BACKGROUND:Mesenchymal stem or stromal cells (MSCs) derived from the induced pluripotent stem cells (iPSCs) have uniform biological activity, which makes the clinical application of MSCs in bone repair possible. Culturing the iPSC-MSCs onto osteoconductive materials is a promising tissue engineering-based strategy in b...

journal_title：Chinese medical journal

authors： Li JY,Wang TT,Li C,Wang ZF,Li S,Ma L,Zheng LL

更新日期：2020-02-05 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF), as a non-invasive treatment of neuropathic pain (NP), has been widely administered clinically. Previous studies have shown that PRF has the potential to improve hyperalgesia in animal models of NP. However, there have been few reports to clarify whether the mechanism of PRF treat...

journal_title：Chinese medical journal

authors： Wang JA,Niu SN,Luo F

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:Blood glucose control is closely related to type 2 diabetes mellitus (T2DM) prognosis. This multicenter study aimed to investigate blood glucose control among patients with insulin-treated T2DM in North China and explore the application value of combining an elastic network (EN) with a machine-learning algor...

journal_title：Chinese medical journal

authors： Wang J,Wang MY,Wang H,Liu HW,Lu R,Duan TQ,Li CP,Cui Z,Liu YY,Lyu YJ,Ma J

更新日期：2020-01-05 00:00:00

abstract：BACKGROUND:Despite the growing epidemic of heart failure (HF), there is limited data available to systematically compare non-cardiac comorbidities in the young-old, old-old, and oldest-old patients hospitalized for HF. The precise differences will add valuable information for better management of HF in elderly patients...

journal_title：Chinese medical journal

authors： Yang MX,An H,Fan XQ,Tao LY,Tu Q,Qin L,Zhang LF,Feng DP,Wang Y,Sun L,Gao S,Guan WZ,Zheng JG,Ren JY

更新日期：2019-12-20 00:00:00

abstract：BACKGROUND:Early diagnosis and accurate staging are important to improve the cure rate and prognosis for pancreatic cancer. This study was performed to develop an automatic and accurate imaging processing technique system, allowing this system to read computed tomography (CT) images correctly and make diagnosis of panc...

journal_title：Chinese medical journal

authors： Liu SL,Li S,Guo YT,Zhou YP,Zhang ZD,Li S,Lu Y

更新日期：2019-12-05 00:00:00

abstract：OBJECTIVE:Renal fibrosis is the most common manifestation of chronic kidney disease (CKD). Noting that existing treatments of renal fibrosis only slow disease progression but do not cure it, there is an urgent need to identify novel therapies. Hydrogen sulfide (H2S) is a newly discovered endogenous small gas signaling ...

journal_title：Chinese medical journal

authors： Wang Y,Xing QQ,Tu JK,Tang WB,Yuan XN,Xie YY,Wang W,Peng ZZ,Huang L,Xu H,Qin J,Xiao XC,Tao LJ,Yuan QJ

更新日期：2019-12-05 00:00:00

abstract：OBJECTIVE:This article aims to present a brief profile of the advances in prevention and treatment of myocardial injury in cancer therapy based on relevant literature or reports. DATA SOURCES:The data cited in this review were obtained from articles indexed in PubMed and China National Knowledge Internet (CNKI) up to ...

journal_title：Chinese medical journal

authors： Miao JX,Gao S,Fan L,Cao F

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Trocar-site hernia (TSH) is a serious complication after laparoscopic procedures. Although it is a rare entity, it can have life-threatening consequences. This study aimed to retrospectively analyze the potential associated factors for TSH following gynecologic laparoscopy and summarize prevention strategies...

journal_title：Chinese medical journal

authors： Zhu YP,Liang S,Zhu L,Sun ZJ,Lang JH

更新日期：2019-11-20 00:00:00