Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.

abstract：BACKGROUND:Cesarean scar pregnancy (CSP) is a very rare but life-threatening entity and there is no optimal management strategy. Here we report a successfully conservative treatment of CSP. METHODS:We retrospectively analyzed the clinical data of 54 women with CSP, who underwent uterine artery embolization between Jan...

journal_title：Chinese medical journal

authors： Cao S,Zhu L,Jin L,Gao J,Chen C

更新日期：2014-01-01 00:00:00

abstract：Background:There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS). We considered that the baseline bleeding risk might be an undetected key factor that significantly affected the efficacy of ticagrelor. Methods:A total of...

journal_title：Chinese medical journal

authors： Wang HY,Li Y,Xu XM,Li J,Han YL

更新日期：2018-09-05 00:00:00

abstract：:The effects of hypoxic endothelial cell conditioned medium (HECCM) on proliferation and collagen synthesis of cultured porcine pulmonary arterial smooth muscle cells (PASMCs) were studied by 3H-thymidine (3H-TdR) and 3H-proline incorporations, image analysis for determination of DNA content and colorimetric assay usin...

journal_title：Chinese medical journal

authors： Sun B,Yuan Y,Zhang W,Che D

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To observe the anti-injury role of recombinant human augmenter of liver regeneration. METHODS:To establish liver injury models induced by CCl4 in vivo and in vitro, cell survival rates and LDH release rates served as observing index in experiments in vitro. Survival rates of liver failure animals, serum conc...

journal_title：Chinese medical journal

authors： Yang X,Wang A,Zhou P,Wang Q,Wei H,Wu Z,He F

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The aim of this research was to evaluate long-term pulmonary sequelae on paired inspiration-expiration thin-section computed tomography (CT) scans 3 years after influenza A (H1N1) virus-associated pneumonia, and to analyze the affecting factors on pulmonary fibrosis. METHODS:Twenty-four patients hospitalize...

journal_title：Chinese medical journal

authors： Xing ZH,Sun X,Xu L,Wu Q,Li L,Wu XJ,Shao XG,Zhao XQ,Wang JH,Ma LY,Wang K

更新日期：2015-04-05 00:00:00

abstract：BACKGROUND:Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). However, only 10% - 20% of chronic heavy cigarette smokers develop symptomatic disease. COPD is most likely the result of complex interactions between environmental and genetic factors. Genetic susceptibility to COPD...

journal_title：Chinese medical journal

authors： Xiao D,Wang C,Du MJ,Pang BS,Zhang HY,Xiao B,Liu JZ,Weng XZ,Su L,Christiani DC

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Nucleostemin is essential for the proliferation and survival of stem and cancer cells, but it is unknown whether this newly identified molecule is involved in prostate cancer pathogenesis. METHODS:Total RNA and protein were extracted from prostate cancer tissues and PC-3, LNCap and DU145 cell lines. The nuc...

journal_title：Chinese medical journal

authors： Liu RL,Zhang ZH,Zhao WM,Wang M,Qi SY,Li J,Zhang Y,Li SZ,Xu Y

更新日期：2008-02-20 00:00:00

abstract：:The solid pseudopapillary tumors of the pancreas (SPTP) are rare tumors, which are commonly found in adolescent women. Radical surgical resection of the primary tumor or metastases is the standard treatment for SPTP and could achieve long-term survival. We reported a case of a 20-year-old female with multiple liver me...

journal_title：Chinese medical journal

authors： Li JX,Wu H,Huang JW,Prasoon P,Zeng Y

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Optical coherence tomography (OCT) is a high resolution noncontact imaging modality which can quantitatively detect the optic disc and retinal structure. This study was designed to evaluate the diagnostic capability of parameters of the optic disc, retinal nerve fiber layer thickness, and ganglion cell compl...

journal_title：Chinese medical journal

authors： Fang Y,Pan YZ,Li M,Qiao RH,Cai Y

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the role of bax in a vincristine (VCR)-induced multidrug-resistant (MDR) human gastric cancer cell line, SGC7901/VCR, in which the Bax protein expression level was significantly lower compared with that in parent cells. METHODS:A bax eukaryotic expression vector was constructed and transfected...

journal_title：Chinese medical journal

authors： Zhao Y,Xiao B,Chen B,Qiao T,Fan D

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Mesenteric artery thrombosis is prone to occur at specific arterial regions with different fluid flow patterns, yet mechanistic links between blood flow and vascular function remain unclear. This study aimd to investigate the role of blood flow in regulation of vascular function and gene expression in rats. ...

journal_title：Chinese medical journal

authors： Xia S,Deng CS

更新日期：2009-05-20 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Du Y,Zhao YX,Liu W,Zhang JW,Yan ZX,Zhou YJ

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:The fluorosis derived from coal burning is a very serious problem in China. By using fluorine-fixing technology during coal burning we are able to reduce the release of fluorides in coal at the source in order to reduce pollution to the surrounding environment by coal burning pollutants as well as decrease t...

journal_title：Chinese medical journal

authors： Yang JL,Chen DQ,Li SM,Yue YL,Jin X,Zhao BC,Ying B

更新日期：2010-02-05 00:00:00

abstract：BACKGROUND:Alzheimer disease (AD) is a neurodegenerative disease related to aging. At present, its pathological mechanisms remain unclear. Family members of the renin-angiotensin system (RAS) play a role in neuronal plasticity, as well as formation of learning and memory. In this study, we explore the effects of altere...

journal_title：Chinese medical journal

authors： Hou DR,Wang Y,Zhou L,Chen K,Tian Y,Song Z,Bao J,Yang QD

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:For patients with severe endometriosis, the spontaneous pregnancy rates have been reported to be near 0 due to extreme distortion of normal pelvic anatomy. Surgery is one of the treatment options; however, if patients failed to conceive after surgery, in vitro fertilization (IVF) is effective. The objective ...

journal_title：Chinese medical journal

authors： Huang XW,Qiao J,Xia EL,Ma YM,Wang Y

更新日期：2010-08-01 00:00:00

abstract：Background:Signal transducer and activator of transcription 3 (STAT3) was strongly expressed and activated in psoriatic keratinocytes (KCs) and correlated with the severity of psoriasis. The study aimed to investigate the effects of STAT3 small interfering RNA (siRNA) combined with ultrasonic irradiation and SonoVue mi...

journal_title：Chinese medical journal

authors： Ran LW,Wang H,Lan D,Jia HX,Yu SS

更新日期：2018-09-05 00:00:00

abstract：:Thallium-201 dipyridamole test (Tl-201DT) has high sensitivity and specificity in the assessment of coronary disease (CAD), but is not always available. We proposed impedance cardiography DT (IDT)instead. To determine the characteristic changes of impedance cardiogram (ICG) in patients with typical angina and to compa...

journal_title：Chinese medical journal

authors： Chen G,Mao HY,Wei KQ,Zhang DC,Guo QG

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Glaucoma can cause progressive damage to retinal ganglion cells. These cells can be classified as cells projecting to the superior colliculus and melanopsin-containing retinal ganglion cells, which project to the suprachiasmatic nucleus. This study was to investigate the effects of chronic intraocular pressu...

journal_title：Chinese medical journal

authors： Wang HZ,Lu QJ,Wang NL,Liu H,Zhang L,Zhan GL

更新日期：2008-06-05 00:00:00

abstract：OBJECTIVE:To review the advances of studies on vitamin D receptor and its role in the pathogenesis of diabetic nephropathy. DATA SOURCES:A comprehensive search of the PubMed literatures without restriction on the publication date was carried out using keywords such as vitamin D receptor and diabetic nephropathy. STUD...

journal_title：Chinese medical journal

authors： Guan X,Yang H,Zhang W,Wang H,Liao L

更新日期：2014-01-01 00:00:00

abstract：:Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliac...

journal_title：Chinese medical journal

authors： Tang DJ,Pang XG

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To investigate all-trans retinoic acid (ATRA) and As2O3 which were found to be able to selectively induce differentiation and apoptosis in acute promyelocytic leukemia (APL) and recently became standard treatment for de novo or relapsed APL. The results of long-term follow up in 72 APL patients were presented...

journal_title：Chinese medical journal

authors： Hu J,Shen Z,Sun H,Wu W,Li X,Sun G,Wang Z

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel re...

journal_title：Chinese medical journal

authors： Tang XF,Zhang JH,Wang J,Han YL,Xu B,Qiao SB,Wu YJ,Chen J,Wu Y,Chen JL,Gao RL,Yang YJ,Yuan JQ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Whether antibody to myelin oligodendrocyte glycoprotein (MOG) can be a diagnostic marker for multiple sclerosis (MS) is still controversial. Recent studies suggested that serum specific anti-MOG epitope antibody might be an MS specific marker. However, these studies did not include neuromyelitis optica (NMO)...

journal_title：Chinese medical journal

authors： Xu Y,Zhang Y,Liu CY,Peng B,Wang JM,Zhang XJ,Li HF,Cui LY

更新日期：2012-09-01 00:00:00

abstract：:Induced pluripotent stem (iPS) cells are a recent development which has brought a promise of great therapeutic values. The previous technique of somatic cell nuclear transfer (SCNT) has been ineffective in humans. Recent discoveries show that human fibroblasts can be reprogrammed by a transient over expression of a sm...

journal_title：Chinese medical journal

authors： Bhowmik S,Li Y

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Natural disasters have been frequent in recent years. Effective treatment of patients with cardiovascular disease following natural disasters is an unsolved problem. We aimed to develop a novel miniature mobile cardiac catheterization laboratory (Mini Mobile Cath Lab) to provide emergency interventional serv...

journal_title：Chinese medical journal

authors： Han YL,Liang Z,Yao TM,Sun JY,Liang M,Huo Y,Wang G,Wang XZ,Liang YC,Meng WH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The Toll-like receptors (TLRs) represent a group of single-pass transmembrane receptors expressed on sentinel cells that are central to innate immune responses.The aim of this study was to investigate the presence of soluble TLRs in pleural effusions, and the diagnostic values of TLRs for pleural effusion wi...

journal_title：Chinese medical journal

authors： Yang HB,Xie KQ,Deng JM,Qin SM

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:A practical problem impeding clinical translation is the limited bone formation seen in artificial bone grafts. Low-pressure/vacuum seeding and dynamic culturing in bioreactors have led to a greater penetration into the scaffolds, enhanced production of bone marrow cells, and improved tissue-engineered bone ...

journal_title：Chinese medical journal

authors： Wang J,Wang J,Yoshinori A,Paul F,Shen H,Chen J,Sotome S,Liu Z,Shinomiya K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the compositions of Th1/Th2/Th3 cells in chronic hepatitis B virus (HBV)-infected individuals by determining the expression of interleukin-4 (IL-4), inetrferon-gamma (IFN-gamma), and transform growth factor-beta (TGF-beta) in single CD4(+) T cells isolated from peripheral blood mononuclear cell...

journal_title：Chinese medical journal

authors： Jiang R,Feng X,Guo Y,Lu Q,Hou J,Luo K,Fu N

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The patients with unprotected left main coronary artery (ULMCA) stenosis and chronic total occlusion (CTO) lesions at the left anterior descending (LAD) artery are often recommended for bypass surgery. However, some of these patients are deemed inoperable or are at high risk for surgery. In this study, we ex...

journal_title：Chinese medical journal

authors： Yang GT,Han YL,Jing QM,Wang SL,Li Y,Ma YY,Wang G,Luan B,Wang XZ,Wang B,Wang ZL,Wang DM

更新日期：2010-04-05 00:00:00