Altered angiotensin-converting enzyme and its effects on the brain in a rat model of Alzheimer disease.

abstract：BACKGROUND:This study was designed to evaluate the relationship between high-density lipoprotein cholesterol (HDL-C) level and acute myocardial infarction (AMI) and coronary heart disease (CHD) death and to explore the protective effect of HDL against CHD in the elderly Chinese. METHODS:Started from 1986, 1211 retiree...

journal_title：Chinese medical journal

authors： Li JZ,Chen ML,Wang S,Dong J,Zeng P,Hou LW

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To clarify the role of sexual related Y (SRY) gene detection in the diagnosis of gonadal dysgenesis. METHODS:Sixteen cases of gonadal dysgenesis were included in this study: 5 with androgen insensitivity syndrome, 1 with 17-alpha-hydroxylase deficiency, 4 with true hermaphrodite, 2 with 45, X/46, XY gonadal ...

journal_title：Chinese medical journal

authors： Yu Q,Huang S,Ye L,Feng L,He F,Ye J,Gu C,Ge Q

更新日期：2001-02-01 00:00:00

abstract：:Anti-HNK-1 monoclonal antibody (MAb) was reactive with non-cancerous and cancerous prostatic epithelia, as well as natural killer cells, myelinated nerves and cells from APUD systems. The expression of HNK-1 antigen on prostate cancer was investigated immunohistochemically by avidinbiotin-peroxidase complex (ABC) meth...

journal_title：Chinese medical journal

authors： Liu X,Zhan B,Tomoyoshi T,Masanori T

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:P53 is one of the most studied tumor suppressors in the cancer research, and over 50% of human tumors carry P53 mutations. MDM-2 is amplified and/or overexpressed in a variety of human tumors of diverse tissue origin. The aim of this study was to examine the expression of P53 protein and MDM-2 protein in gli...

journal_title：Chinese medical journal

authors： Wang AL,Liu ZX,Li G,Zhang LW

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:In the era of highly active antiretroviral therapy (HAART), the use of antiretrovirals as post-exposure prophylaxis (PEP) was the most important strategy for preventing occupational exposure to blood or fluids containing human immunodeficiency virus (HIV). The objective of this study was to retrospectively e...

journal_title：Chinese medical journal

authors： Cai J,Xiao J,Zhang Q

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:So far, most of the surgical techniques for congenital blepharophimosis syndrome are two-stage procedures. In this study, we investigated a modified one-stage procedure to reduce the suffering of patients. METHODS:From 2003 to 2005, we adopted an one-stage technique combining blepharoptosis correction with ...

journal_title：Chinese medical journal

authors： Huang WQ,Qiao Q,Zhao R,Wang XJ,Fang XQ

更新日期：2007-08-20 00:00:00

abstract：BACKGROUND:Long-term use of benzalkonium chloride (BAC)-preserved drugs is often associated with ocular surface toxicity. Ocular surface symptoms had a substantial impact on the glaucoma patients' quality of life and compliance. This study aimed to investigate the effects of sodium hyaluronate (SH) on ocular surface to...

journal_title：Chinese medical journal

authors： Liu X,Yu FF,Zhong YM,Guo XX,Mao Z

更新日期：2015-09-20 00:00:00

abstract：BACKGROUND:Severe valgus deformity often has bone defect and laxity of the medial ligamentous, and total knee arthroplasty in severe valgus knee is, in most cases, more challenging for surgeons. The usefulness of a computer assisted navigation system in reestablishing the mechanical axis has been well established. Henc...

journal_title：Chinese medical journal

authors： Shao JJ,Zhang XL,Wang Q,Chen YS,Shen H,Jiang Y

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Current treatments for scoliosis have some defects and complications. To study spinal deformities and test novel scoliosis treatments, many animal models of scoliosis have been developed. These models applied a single load to the spine and could not precisely modulate the spinal growth in different dimension...

journal_title：Chinese medical journal

authors： Zhang HY,Li QY,Wu ZH,Zhao Y,Qiu GX

更新日期：2017-11-05 00:00:00

abstract：OBJECTIVE:To investigate the use of the Gibbs-Sampler method in evaluating the relationship between clinic events and health risks in a meta-analysis of multiple clinical trials. METHODS:By using a generalized linear model with random-effects, Gibbs-Sampler technique was used in a meta-analysis of multiple clinical tr...

journal_title：Chinese medical journal

authors： Wang Y,Wang Y,Li L,Wang Z,Macus F,Salim Y

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To investigate the mechanism of multidrug resistance (MDR) in a human glioma cell and methods for overcoming multi-drug resistance. METHODS:MDR cell line C(6)/adr was established. The expression of the mdr-1 gene and its P-glycoprotein (P-gp) in the C(6)/adr cell line was observed by RT-PCR and flow cytometr...

journal_title：Chinese medical journal

authors： Liu F,Wang C,Zhang Q,Li J,Zhang Y

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:In patients with chronic total occlusion (CTO) and multivessel coronary artery disease, the comparison of surgical and the percutaneous revascularization strategies has rarely been conducted. The aim of this study was to compare long term clinical outcomes of drug eluting stent (DES) implantation with corona...

journal_title：Chinese medical journal

authors： Liu W,Ma CS,Kang JP,Du X,Chen F,Zhou YJ,Lü SZ,Huang FJ,Gu CX,Zhu XL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Ophthalmic gel has been developed to increase the drug concentration in aqueous humor and to retard the loss of drug from the conjunctival sac. The research was to compare the drug concentration in aqueous humor of cataract patients administered 0.3% gatifloxacin ophthalmic gel with that in patients administ...

journal_title：Chinese medical journal

authors： Liu X,Wang NL,Wang YL,Ma C,Ma L,Gao LX,Huang YX,Xiong SH,Wang K

更新日期：2010-08-05 00:00:00

abstract：OBJECTIVE:To summarize the recent findings on the epidemiology of medically important, opportunistic invasive fungal infections (IFIs) in China and discuss the relevant social, economical reasons and medical factors. DATA SOURCES:We performed a comprehensive search of both English and Chinese literatures of opportunis...

journal_title：Chinese medical journal

authors： Liao Y,Chen M,Hartmann T,Yang RY,Liao WQ

更新日期：2013-01-01 00:00:00

abstract：Background:Pompe disease is a rare lysosomal glycogen storage disorder linked to the acid alpha-glucosidase gene (GAA). A wide clinical and genetic variability exists between patients from different ethnic populations, and the genotype-phenotype correlations are still not well understood. The aim of this study was to r...

journal_title：Chinese medical journal

authors： Liu HX,Pu CQ,Shi Q,Zhang YT,Ban R

更新日期：2018-02-20 00:00:00

abstract：BACKGROUND:Artificial joints present certain problems such as osteal absorption and lysis induced by wear debris which leads to loosening of the prosthesis over a period of time. Here we propose a design of an artificial magnetic suspension joint that was prepared by integrating the medical theories of modern material ...

journal_title：Chinese medical journal

authors： Dai M,Nie T

更新日期：2010-12-01 00:00:00

abstract：:Anastomotic false aneurysm (AFA) of the aorta is a potentially lethal complication after prosthetic grafting. Nineteen aneurysms were encountered in 18 patients within a 30-year period (1960-1991). There were 10 men and 8 women, aged 27-80 years (mean 58 years). In 14 patients, the prostheses were made of silk, in 2 w...

journal_title：Chinese medical journal

authors： Chen FZ,Xu X,Fu WG,Wu ZG

更新日期：1994-11-01 00:00:00

abstract：:Percutaneous balloon mitral valvuloplasty (PBMV) was successfully performed in 50 selected patients with mitral stenosis by using Inoue pillow-shaped balloon and Inoue technique. The average diameter of balloon used was 26.9 +/- 0.9 mm. 90% (45/50) of cases had either double or single mitral commissura split. Of the r...

journal_title：Chinese medical journal

authors： Fang WY,Yu WX,Lu ZX,Li XM,Bu DX,Xu WL

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To examine the effect of selective head cooling (SHC) on brain cell membrane activity involving ATPase, phospholipase A2, content of total membrane phospholipids during postischemic reperfusion, so as to elucidate the possible underlying mechanism on resuscitating effect of SHC. MATERIALS AND METHODS:Complet...

journal_title：Chinese medical journal

authors： Duan M,Li D,Xu J

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of active immunotherapy with anti-idiotypic vaccine in patients with nasopharyngeal carcinoma (NPC). METHODS:Anti-idiotypic antibodies (2H4/5D3) bearing the internal image of the NPC antigen were used in active immunotherapy in NPC patients receiving radiotherapy. Antibodies and cyt...

journal_title：Chinese medical journal

authors： Li G,Xie L,Zhou G,Fu H,Zhou J,Sun Q

更新日期：2002-04-01 00:00:00

abstract：Objective:Endothelial cells (ECs) are important metabolic and endocrinal organs which play a significant role in regulating vascular function. Vascular ECs, located between the blood and vascular tissues, can not only complete the metabolism of blood and interstitial fluid but also synthesize and secrete a variety of b...

journal_title：Chinese medical journal

authors： Meng LB,Chen K,Zhang YM,Gong T

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:The present study was aimed to investigate the usage of aspirin for the secondary prevention of ischemic stroke, evaluate the correlated factors, and analyze the reasons for not taking and irregularly taking aspirin. METHODS:The patients in this group were all stroke survivors who have formerly been diagnos...

journal_title：Chinese medical journal

authors： Ke XJ,Yu YF,Guo ZL,Xu K,Hai H,Zhang AH,Jiang H,Peng H

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:The development of the targeted signal transduction inhibitor STI571 has prompted us to treat chronic myeloid leukemia in different ways. Since STI571 may reverse multidrug-resistance of K562/MDR cells in vitro, we studied the effect of STI571 on multidrug-resistant K562 cells in vivo. METHODS:Multidrug-res...

journal_title：Chinese medical journal

authors： Gao L,Chen L,Fei XH,Qiu HY,Zhou H,Wang JM

更新日期：2006-06-05 00:00:00

abstract：BACKGROUND:Development of vulnerable lesions is not limited to the target lesions, but a pan-coronary process. Such lesions are identified by positive remodeling (intravascular ultrasound (IVUS) and complex lesions (angiography)). The prevalence of lesions with vulnerable characteristics in patients with stable angina ...

journal_title：Chinese medical journal

authors： Sun L,Lü SZ,Jin ZN,Song XT

更新日期：2010-04-05 00:00:00

abstract：BACKGROUND:During the last 3 decades, China has dramatic changes of the dietary pattern among its citizens, particularly in urban cities. This study aimed to determine the nutrient intake status and factors associated with nutrient intakes of urban Chinese pregnant women now-a-day. METHODS:The multistage stratified ra...

journal_title：Chinese medical journal

authors： Liu FL,Zhang YM,Parés GV,Reidy KC,Zhao WZ,Zhao A,Chen C,Ning CY,Zheng YD,Wang PY

更新日期：2015-07-05 00:00:00

abstract：BACKGROUND:Aquired immune deficiency syndrome (AIDS) presents a challenge to medical researchers because of its unique pathological and clinical picture. The clinical data, particularly autopsy evidence, from China have failed to provide enough pathological and etiological evidence for AIDS diagnosis, which impairs the...

journal_title：Chinese medical journal

authors： Li HJ,Gao YQ,Cheng JL,Zhang YZ

更新日期：2009-09-20 00:00:00

abstract：:Apolipoprotein (a) [Lp(a)] phenotypes of 69 myocardial infarction survivor and 56 stroke patients were reported and compared to those of 190 healthy Chinese. The results revealed that the distributions of apo(a) phenotype frequency in patients with cardio-cerebrovascular disease (CCVD) were different from those of con...

journal_title：Chinese medical journal

authors： Zhuang YY,Li JJ,Wang JJ

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:Dermoscopy is a useful technique for improving the diagnostic accuracy of various types of skin disorders. In China, dermoscopy has been widely accepted, and domestic researchers have made tremendous progress in the field of dermoscopy. The main purpose of this review is to summarize the current status of der...

journal_title：Chinese medical journal

authors： Shen X,Yu RX,Shen CB,Li CX,Jing Y,Zheng YJ,Wang ZY,Xue K,Xu F,Yu JB,Meng RS,Cui Y

更新日期：2019-09-05 00:00:00

abstract：OBJECTIVE:To review the progress of cardiac differentiation and electrophysiological characteristics of bone marrow mesenchymal stem cells. DATA SOURCES:The databases of PubMed, Springer Link, Science Direct and CNKI were retrieved for papers published from January 2000 to January 2012 with the key words of "bone marr...

journal_title：Chinese medical journal

authors： Liu BW,Lü AL,Hou J,Huang W,Li Y,Hou ZL,Hou H,Da J,Yang N,Ai SY

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of different doses of intravenous domestic urokinase. METHODS:One thousand and twenty three cases of acute myocardial infarction within 6 hours after acute onset were divided randomly into two groups with 539 cases in the low dose group (urokinase 22,000IU/kg, total dose not lower ...

journal_title：Chinese medical journal

authors：

更新日期：1997-01-01 00:00:00