STI571 combined with vincristine greatly suppressed the tumor formation of multidrug-resistant K562 cells in a human-nude mice xenograft model.

abstract：BACKGROUND:Congenital heart defects with intractable hypoplasia of the pulmonary arteries without intercourse or with intercourse stenosis is unsuitable for surgical correction or regular palliative procedures. We reported our experience with combined palliative procedures for congenital heart defects with intractable ...

journal_title：Chinese medical journal

authors： Fan XM,Zhu YB,Su JW,Zhang J,Li ZQ,Xu YQ,Li XF,Liu YL

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To report the surgical techniques and results of an 8-year follow-up study of 42 patients with a modified orthotopic ileal neobladder restoring normal anatomical relationship. METHODS:Total cystoprostatectomy was performed extraperitoneally. A 45 - 50 cm segment of the ileal loop was isolated, detubularized,...

journal_title：Chinese medical journal

authors： Huang J,Xu K,Yao Y,Guo Z,Lin T,Jiang C

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:In county-level tuberculosis (TB) dispensaries in China, the accurate diagnosis of sputum smear-negative pulmonary tuberculosis (SNPT) needs to be improved by developing and validating clinical and radiographic predictors. METHODS:The study was conducted simultaneously in three counties per province in Chon...

journal_title：Chinese medical journal

authors： Li XX,Jiang SW,Zhang H,Jing KH,Wang L,Li WB,Liu XQ,Yao HY,Wang LX

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Genetic factors can influence antihypertensive response to metoprolol, and many studies focused on the relationship between the genotype in beta1-adrenergic receptor and blood pressure (BP), little was known about the association of angiotensin-converting enzyme (ACE) genotype with the therapeutic result of ...

journal_title：Chinese medical journal

authors： Liu LW,Liu H,Chen GL,Huang YL,Han LL,Xu ZM,Jiang XJ,Li YS

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To investigate changes in intestinal microflora in patients with chronic severe hepatitis (CSH), and their role in this life-threatening disease. METHODS:We classified nineteen patients with chronic severe hepatitis as the CSH group, thirty patients with chronic hepatitis (CH) as the CH group and thirty-one ...

journal_title：Chinese medical journal

authors： Li L,Wu Z,Ma W,Yu Y,Chen Y

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of using melanoma antigen-1 (MAGE-1) peptide as a tumor vaccine to treat hepatocellular carcinoma (HCC). METHODS:The expressions of MAGE-1 in 8 HCC cell lines and in liver cancer tissue from a patient were detected using RT-PCR. The type of human leucocyte antigen I(HLA I) of b...

journal_title：Chinese medical journal

authors： Lu J,Leng X,Peng J,Mou D,Pang X,Shang X,Chen W

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Cardiovascular diseases, especially coronary artery disease (CAD), are major causes of death in industrialized countries. Elevated concentrations of plasma homocysteine (Hcy) have been associated with an increased risk of CAD. Increased plasma levels of chemokine, characterized by their ability to induce mig...

journal_title：Chinese medical journal

authors： Wang G,Mao JM,Wang X,Zhang FC

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The anterior cruciate ligament (ACL) is one of the most commonly injured knee ligaments. Even following ACL reconstruction, significant articular cartilage degeneration can be observed and most patients suffer from premature osteoarthritis. Articular cartilage degeneration and osteoarthritis development afte...

journal_title：Chinese medical journal

authors： Shi DL,Wang YB,Ai ZS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The importance of polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene for the prediction of the response to fluorouracil-based adjuvant chemotherapy in gastric cancer patients remains unclear. The aim of this study is to assess the predictive value of several polymorphisms of the MTHFR gene...

journal_title：Chinese medical journal

authors： Zhang X,Bai Z,Chen B,Feng J,Yan F,Jiang Z,Zhong Y,Wu J,Cheng L,Lu Z,Tong N,Zhang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Anisodamine is widely used in therapy for treating acute glomerulonephritis and diabetic nephropathy because it can improve renal microcirculation. We performed a study to evaluate the preventive effects of anisodamine against contrast-induced nephropathy (CIN) in type 2 diabetics with renal insufficiency un...

journal_title：Chinese medical journal

authors： Geng W,Fu XH,Gu XS,Wang YB,Wang XC,Li W,Jiang YF,Hao GZ,Fan WZ,Xue L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Mitochondrial DNA 4977-bp deletion (DeltamtDNA(4977)) was reported in many human neoplasia. However, its biological significance remains to be evaluated and the molecular mechanism needs to be investigated. In this study, we analyzed the frequency of DeltamtDNA(4977) in gastric cancer (GC) cell lines and tis...

journal_title：Chinese medical journal

authors： Wang J,Lü YY

更新日期：2009-02-20 00:00:00

abstract：BACKGROUND:Pioglitazone may be beneficial in the treatment of psoriasis. However, based on the effectiveness and safety considerations, it has not been widely used. To fully evaluate the strength of evidence supporting psoriasis treatment with pioglitazone, we conducted a meta-analysis of existing published studies. M...

journal_title：Chinese medical journal

authors： Zhang JZ,Ding Y,Xiang F,Yu SR,Zhang DZ,Guan MM,Kang XJ

更新日期：2020-02-20 00:00:00

abstract：OBJECTIVE:To have a better understanding of genetic contributions to the development of obstructive sleep apnea hypopnea syndrome (OSAHS) by reviewing studies on its genetic basis. DATA SOURCES:A comprehensive search of the PubMed literature without restriction on the publication date was carried out using terms "obst...

journal_title：Chinese medical journal

authors： Zhang D,Xiao Y,Luo J

更新日期：2014-01-01 00:00:00

abstract：:The results of 31 cases of sutureless esophagogastrostomy by intraluminal elastic circular ligation (IECL) with the biodegradable supporting tube were reported. The fate of the supporting tube could be tracked satisfactorily by X-ray. The tube-dislodge time was 15.03 +/- 2.23 days and unaffected by the size of support...

journal_title：Chinese medical journal

authors： Chen L,Zhang Y,Du X,Wang Q,Zhang Z

更新日期：1995-10-01 00:00:00

abstract：Background:Macrophage polarization is involved in the development of many diseases such as obesity, diabetes, and cancer. This study aimed to understand the trends and hotspots of macrophage polarization research. Methods:We searched through the Web of Science Core Collection database to obtain original articles in th...

journal_title：Chinese medical journal

authors： Gao H,Huang FY,Wang ZP

更新日期：2018-12-20 00:00:00

abstract：OBJECTIVE:To provide epidemiological data for revising the diagnostic criteria of neonatal hyperbilirubinemia in China. METHODS:A survey was performed among full-term infants in multiple centers throughout the country. From less than 24 hours after birth, the infants' bilirubin levels were measured every day until the...

journal_title：Chinese medical journal

authors： Ding G,Zhang S,Yao D,Na Q,Wang H,Li L,Yang L,Huang W,Wang Y,Xu J

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Tumor involving the septum pellucidum is uncommon. Surgery as the main therapeutic procedure for this lesion is a challenge to neurosurgeons. We analyzed the clinical characteristics and pathological features of septum pellucidum tumor in 41 patients and compared the curative effects of frontal transcortical...

journal_title：Chinese medical journal

authors： Wang L,Zhang MZ,Zhang W,Zhao SF,Zhao JZ,Jia JX

更新日期：2005-05-20 00:00:00

abstract：BACKGROUND:With the technical advances, magnetic resonance imaging (MRI) is now sensitive enough to detect subtle structural abnormalities of ocular motor nerves arising from the brainstem and orbits of living subjects. This study was designed to delineate the MRI characteristics in patients with special forms of strab...

journal_title：Chinese medical journal

authors： Jiao YH,Zhao KX,Wang ZC,Qian XH,Wu X,Man FY,Lu W,She HC

更新日期：2009-12-20 00:00:00

abstract：BACKGROUND:Among patients with advanced multivessel coronary disease, left ventricular (LV) function is widely variable, and clinical and angiographic correlates of ventricular dysfunction remain to be defined. METHODS:Among 73 339 patients undergoing diagnostic cardiac catheterization at a single center in China, pat...

journal_title：Chinese medical journal

authors： Gao Z,Xu B,Yang YJ,Kandzari DE,Yuan JQ,Chen J,Chen JL,Qiao SB,Wu YJ,Yan HB,Qin XW,Yao M,Liu HB,Dai J,Chen T,Teng SY,Gao RL

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To isolate and clone the tumor suppressor gene on chromosomal region 7q32 correlated with the carcinogenesis of human nasopharyngeal carcinoma (NPC). METHODS:The genotypes of polymorphic microsatellite markers on 7q32 in DNA from 24 biopsies of nasopharyngeal carcinoma and matched normal blood cells were ide...

journal_title：Chinese medical journal

authors： Jiang N,Zhan F,Tan G,Deng L,Zhou M,Cao L,Qiu Y,Xie Y,Li G

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To investigate the antitumor immune efficiency of mouse dendritic cells (mDCs) by using adenovirus-mediated tumor necrosis factor-alpha (AdV-TNF-alpha) gene transfer. METHODS:MDCs infected with AdV-TNF-alpha and AdV-pLpA (no gene insert) at 100 multiplicity of infection (MOI) were analyzed by RNase protectio...

journal_title：Chinese medical journal

authors： Zhang W,Yang H,Wang Z,Jim X

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Postoperative preablative stimulated thyroglobulin (ps-Tg) has been evaluated in predicting prognosis and success of ablation regarding differentiated thyroid cancer (DTC); however, its relationship with recurrence risk and radioiodine decision-making remains uncertain, especially in Chinese DTC patients. We...

journal_title：Chinese medical journal

authors： Yang X,Liang J,Li TJ,Yang K,Liang DQ,Yu Z,Lin YS

更新日期：2015-04-20 00:00:00

abstract：BACKGROUND:C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine the technical feasibility and safety of CBCT venography in the diagnosis of IVCS compared with conventional venography...

journal_title：Chinese medical journal

authors： Wang CM,Zhang WL,Li X

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:In dental clinics, dentition defects are commonly restored with conventional porcelain-fused-to-metal fixed bridges. However, Ni-Cr alloy ceramic fixed bridges are known to have several drawbacks such as marginal coloration of the neck, low casting precision and, most seriously, poor biocompatibility. These ...

journal_title：Chinese medical journal

authors： Zhang XH,Sun F,Wang H,Xu MQ

更新日期：2008-10-05 00:00:00

abstract：BACKGROUND:Optical coherence tomography (OCT) is a high resolution noncontact imaging modality which can quantitatively detect the optic disc and retinal structure. This study was designed to evaluate the diagnostic capability of parameters of the optic disc, retinal nerve fiber layer thickness, and ganglion cell compl...

journal_title：Chinese medical journal

authors： Fang Y,Pan YZ,Li M,Qiao RH,Cai Y

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:The human leukocyte antigen-G (HLA-G) has been considered to be an important tolerogeneic molecule playing an essential role in maternal-fetal tolerance, upregulated in the context of transplantation, malignancy, and inflammation, and has been correlated with various clinical outcomes. The aim of this study ...

journal_title：Chinese medical journal

authors： Xiao L,Zhou WQ,Shi BY,Feng K,He XY,Wei YX,Gao Y,Meng XY,Xiao W

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The molecular mechanisms underlying the endometriosis are still not completely understood. In order to test the hypothesis that the approaches in phosphoproteomics might contribute to the identification of key biomarkers to assess disease pathogenesis and drug targets, we carried out a phosphoproteomics anal...

journal_title：Chinese medical journal

authors： Xu HM,Deng HT,Liu CD,Chen YL,Zhang ZY

更新日期：2015-10-05 00:00:00

abstract：OBJECTIVE:To investigate the effects of the combination of octreotide and aspirin on the growth of gastric cancer. METHODS:Proliferation of gastric cancer cell lines treated with octreotide or aspirin was determined by (3)H-thymidine incorporation. After xenografts of human gastric cancer were implanted orthotopically...

journal_title：Chinese medical journal

authors： Tang C,Wang C,Tang L

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To observe the anti-injury role of recombinant human augmenter of liver regeneration. METHODS:To establish liver injury models induced by CCl4 in vivo and in vitro, cell survival rates and LDH release rates served as observing index in experiments in vitro. Survival rates of liver failure animals, serum conc...

journal_title：Chinese medical journal

authors： Yang X,Wang A,Zhou P,Wang Q,Wei H,Wu Z,He F

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The optimal timing of surgical revascularization for patients presenting with ST-segment elevation myocardial infarction (STEMI) and impaired left ventricular function is not well established. This study aimed to examine the timing of surgical revascularization after STEMI in patients with ischemic heart dis...

journal_title：Chinese medical journal

authors： Wang R,Cheng N,Xiao CS,Wu Y,Sai XY,Gong ZY,Wang Y,Gao CQ

更新日期：2017-02-20 00:00:00