Angiotensin-converting enzyme gene I/D genotype affected metoprolol-induced reduction in 24-hour average heart rate.

abstract：:Osteoarthritis (OA) models in bipedal rats were used to study the immune response, including the changes of IgG, antibody dependent cytotoxicity tests toward articular chondrocytes and the matrix. The results revealed significant difference between the bipedal and the quadruped rats. Immunological studies have proved ...

journal_title：Chinese medical journal

authors： Chen YP,Yang Y,Chen BX

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:In tumors the process of apoptosis occurs over an interval of time after chemotherapy. It is important to determine the best time for detecting apoptosis by in vivo imaging. In this study, we evaluated the dynamics and feasibility of imaging non-small cell lung cancer (NSCLC) apoptosis induced by paclitaxel ...

journal_title：Chinese medical journal

authors： Zheng YM,Wang F,Fang W,Hua ZC,Wang ZZ,Meng QL,Yan J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A simple, safe and effective therapeutic strategy for traumatic instability of the subaxial cervical spine, as well as its prognostic assessment, is still controversial. METHODS:The therapeutic options for 83 patients of traumatic instability of the subaxial cervical spine, whose average age was 35 years, w...

journal_title：Chinese medical journal

authors： Cao P,Liang Y,Gong YC,Zheng T,Zhang XK,Wu WJ

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:While combined oral contraceptives (COCs) are commonly used to treat polycystic ovary syndrome (PCOS), comparative data regarding metabolic effects of different progestogens on this patient population are missing. This study aimed to compare the different effects of drospirenone (DRP)-containing COCs with cy...

journal_title：Chinese medical journal

authors： Wang QY,Song Y,Huang W,Xiao L,Wang QS,Feng GM

更新日期：2016-04-20 00:00:00

abstract：BACKGROUND:Cornea epithelial cells play early and crucial roles in the initiation of ocular surface responses to pathogens. Participation of toll-like receptor (TLR) 2 and TLR4, which are major forms of fungi receptors, may be involved in Aspergillus fumigatus induced immune responses. The objective of the present stud...

journal_title：Chinese medical journal

authors： Zhao J,Wu XY

更新日期：2008-03-05 00:00:00

abstract：:Eight strains of sonicated Helicobacter pylori (H. pylori) were pooled as group antigen to detect the serum IgG antibody to H. pylori in patients with various gastroduodenal diseases and subjects at health check-up. The enzyme-linked immunosorbent assay method used had a sensitivity of 94%, a specificity of 87%, and a...

journal_title：Chinese medical journal

authors： Xiao SD,Pan ZJ,Zhang ZH,Jiang SJ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Some esophageal cancer patients complicated with depression exhibit cognitive impairments. Frontal electroencephalogram (EEG) may be used as a reliable biomarker for prefrontal-mediated cognitive functions. This study was to investigate alterations of EEG and frontal cognitive impairment in esophageal cancer...

journal_title：Chinese medical journal

authors： Cao Y,Chen X,Xie H,Zou L,Hu LJ,Zhou XJ

更新日期：2017-08-05 00:00:00

abstract：OBJECTIVE:To clarify the role of these cyclins in human gastric cancer. METHODS:38 gastric cancer patients, 29 first degree relatives of gastric cancer patients, as well as 18 healthy subjects were included. The mRNA expression of cyclins D1, D2, D3 and E in gastric biopsies was evaluated by RT-PCR analysis using spec...

journal_title：Chinese medical journal

authors： Yu J,Miehlke S,Ebert MP,Szokodi D,Wehvnignh B,Malfertheiner P,Ehninger G,Bayerdoerffer E

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Recent studies have suggested that cancer stem cells cause tumor recurrence based on their resistance to radiotherapy and chemotherapy. Although the highly invasive nature of glioblastoma cells is also implicated in the failure of current therapies, it is not clear whether cancer stem cells are involved in i...

journal_title：Chinese medical journal

authors： Yu SP,Yang XJ,Zhang B,Ming HL,Chen C,Ren BC,Liu ZF,Liu B

更新日期：2011-09-01 00:00:00

abstract：:T-lymphocyte subsets, B-lymphocyte, immunoglobulins and complement were studied in 38 children with Henoch Schonlein Purpura (HSP) in the acute stage. They had significantly lower CD3 percentage and lymphocyte blastogenesis rate, greater CD8 variation coefficient and B-lymphocyte percentage and higher levels immunoglo...

journal_title：Chinese medical journal

authors： Sun XC,Chen MY,Cheng AS,Xu DL

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To study the effects of skeletal muscle satellite cells implanted into infarcted myocardium on the volume of remnant myocytes. METHODS:Thirty-six adult mongrel canines were divided randomly into implantation group and control group. In the implantation group, skeletal muscle satellite cells taken from the gl...

journal_title：Chinese medical journal

authors： Zhong H,Zhu H,Wei H,Zhang Z

更新日期：2003-07-01 00:00:00

abstract：:From 1949 through 1978, 31 patients with renal metastasis were diagnosed in a total of 448 cases of choriocarcinoma admitted to our hospital, giving an incidence of 6.9%. Renal metastasis was invariably preceded by pulmonary metastases and usually accompanied by other visceral metastases, indicating that renal metasta...

journal_title：Chinese medical journal

authors： Wang YE,Song HZ,Yang XY,Dong SY,Gan N

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:To identify novel tumor suppressor genes at chromosome 3p24-26 in human nasopharyngeal carcinoma (NPC). METHODS:Twenty epithelial-derived expressed sequence tags (EST) were selected from chromosome 3p24-26. RT-PCR and Northern blot were used to detect the expression of the ESTs in NPC cell line, HNE-1, and p...

journal_title：Chinese medical journal

authors： Xie Y,Bin L,Yang J,Li Z,Yu Y,Zhang X,Cao L,Li G

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Our previous research has suggested that genes around D12S1056 in 12q13 may confer susceptibility to ventricular septal defect (VSD) in humans. The present study was to define the chromosome region assignment by transmission disequilibrium test (TDT), and to identify the important candidate gene by family-ba...

journal_title：Chinese medical journal

authors： Qiu GR,Gong LG,He G,Xu XY,Xin N,Sun GF,Yuan YH,Sun KL

更新日期：2006-02-20 00:00:00

abstract：:The extent of participation and changes of glycophorins (GPs) and membrane proteins in the merozite-human erythrocyte interaction during the invasion of Plasmodium falciparum (Pf) were studied by immunoblotting techniques. Polyclonal antisera to alpha GP and to its C-terminal fragment (residues 82-131) as well as M an...

journal_title：Chinese medical journal

authors： Liu JF,Lu YQ,Roth EF Jr,Nagel RL,Blumenfeld OO

更新日期：1993-04-01 00:00:00

abstract：:Satisfactory results have been obtained in treating infective shock with injection of natural Fructus Aurantii immaturus (nat-FAI). The results of animal experiments and clinical observations on the anti-shock effects of the synthetic effective compositions of Fructus Aurantii immaturus (syn-FAI) are reported. The car...

journal_title：Chinese medical journal

authors： Zhao XW,Li JX,Zhu ZR,Sun DQ,Liu SC

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2), one of the major metabolites from prostaglandin D2 in arachidonic acid metabolic pathway, has potential anti-inflammatory properties. The objective of this study was to explore the effects of 15d-PGJ2-loaded poly(D,L-lactide-co-glycolide) nanocapsules (15d-PGJ2-NC...

journal_title：Chinese medical journal

authors： Tang Q,Chen LL,Wei F,Sun WL,Lei LH,Ding PH,Tan JY,Chen XT,Wu YM

更新日期：2017-02-05 00:00:00

abstract：BACKGROUND:Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for a...

journal_title：Chinese medical journal

authors： Ren JH,Ma N,Wang SY,Sun YJ,Zhang YW,Guo FJ,Li YJ,Li TH,Ai H,Zhang WD,Li P,Ma WH

更新日期：2019-01-05 00:00:00

abstract：BACKGROUND:The growing enthusiasm for coronary artery bypass grafting (CABG) without cardiopulmonary bypass (CPB) is emerging, but the role of off-pump coronary artery bypass (OPCAB) in clinical practice remains controversial. The purpose of this study was to assess differences in the incidences of stroke, atrial fibri...

journal_title：Chinese medical journal

authors： Chen YB,Shu J,Yang WT,Shi L,Guo XF,Wang FG,Qian YY

更新日期：2012-01-01 00:00:00

abstract：:Type 2 diabetes mellitus and metabolic disorders have become an epidemic globally. However, the pathogenesis remains largely unclear and the prevention and treatment are still limited. In addition to environmental factors during adulthood, early life is the critical developmental window with high tissue plasticity, wh...

journal_title：Chinese medical journal

authors： Zhou LY,Deng MQ,Zhang Q,Xiao XH

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Bardet-Biedl syndrome (BBS) is a genetically heterogeneous disease, and information about BBS in Chinese populations is very limited. The purpose of the present study was to determine the genetic cause of BBS in a Chinese Han family. METHODS:Clinical data were recorded for the 4-year-old female proband and ...

journal_title：Chinese medical journal

authors： Li Q,Zhang Y,Jia L,Peng X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Cholesterol-lowering therapy with statins has been reported to reduce the morbidity and mortality of cardiovascular diseases. This study aimed to investigate the effects of combined application of extended-release niacin and atorvastatin on lipid profile modification and the risks of adverse events in patien...

journal_title：Chinese medical journal

authors： Sang ZC,Wang F,Zhou Q,Li YH,Li YG,Wang HP,Chen SY

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Patients with elevated admission glucose levels may be at increased risk of death after myocardial infarction, independent of other baseline risk factors and more severe coronary artery disease. However, data regarding admission glucose and epicardial and microvascular flow after primary angioplasty is limit...

journal_title：Chinese medical journal

authors： Shen XH,Jia SQ,Li HW

更新日期：2006-01-20 00:00:00

abstract：BACKGROUND:Caspases are important in the signaling pathway of cellular apoptosis. Caspase-3 protein expression has been shown to increase and parallel to neuronal apoptosis in retinal ischemia injury. This study was to determine whether caspase-1 is involved in neuronal cell death or in retinal ischemia and reperfusion...

journal_title：Chinese medical journal

authors： Zheng GY,Zhang C,Li ZG

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Methylmalonic acidemia (MMA) is a multifactorial autosomal recessive inborn error of organic acid metabolism, often presenting with neurological symptoms. As neurological disorders are often related to white matter injury, diffusion tensor imaging (DTI) is an excellent tool for assessment of white matter inj...

journal_title：Chinese medical journal

authors： Gao Y,Guan WY,Wang J,Zhang YZ,Li YH,Han LS

更新日期：2009-04-20 00:00:00

abstract：OBJECTIVES:To study the interrelation between nitric oxide (NO) and endothelin-1 (ET1) in experimental acute hypoxic rats, and to evaluate the mechanism of acute hypoxic pulmonary hypertension affected by NO and ET1 and its intervention. METHODS:Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemi...

journal_title：Chinese medical journal

authors： Wang Y,Zhang L,Shen W,Chen L,Fan S

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (GVHD), the commonest long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT), has a negative impact on patients' health related quality of life (HRQoL). This study was designed to investigate the HRQoL in patients with chronic GVHD in China. ...

journal_title：Chinese medical journal

authors： Mo XD,Xu LP,Liu DH,Chen YH,Zhang XH,Chen H,Han W,Wang Y,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2013-08-01 00:00:00

abstract：:A rare type of annular pancreas, in which the tail of the annular duct is fused with the dorsal pancreatic duct to form the main duct, and its diagnostic imagings of endoscopic retrograde cholangiopancreatography, hypotonic duodenography, computed tomography and ultrasound are described. Annular pancreas is an anomaly...

journal_title：Chinese medical journal

authors： Lin SZ

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the diagnosis and aggressive surgical approach for brainstem tumors. METHODS:A series of 24 adult patients with brainstem tumors were involved. Magnetic resonance (MR) imaging was performed on all patients. Surgical technique, potential risk and management of complications were described. RESULT...

journal_title：Chinese medical journal

authors： Xu Q,Bao W,Mao R

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Image-guided radiation therapy (IGRT) is the preferred method for curative treatment of localized prostate cancer, which could improve disease outcome and reduce normal tissue toxicity reaction. IGRT using cone-beam computed tomography (CBCT) in combination with volumetric-modulated arc therapy (VMAT) potent...

journal_title：Chinese medical journal

authors： Li M,Li GF,Hou XY,Gao H,Xu YG,Zhao T

更新日期：2016-06-20 00:00:00