Genetics of obstructive sleep apnea/hypopnea syndrome.

abstract：OBJECTIVE:To determine the effects and toxicity of interstitial brachytherapy using iridium-192 on brain malignant gliomas. METHODS:Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high-activity iridi...

journal_title：Chinese medical journal

authors： Liu Z,Yu X,Guo Y,Li S,Cui Y,Yu X,Yuan Z,Kang J

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To investigate the role of AC-cAMP system in the transmission of the action of the growth hormone releasing hormone (GRH) on growth hormone (GH) release in pituitary GH-secreting adenomas. METHODS:The effects of GRH (10(-7) mol/L) on intracellular cAMP levels and GH release and the effects of AC-cAMP stimula...

journal_title：Chinese medical journal

authors： Shi Y,Deng J,Yin J

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Human urotensin II (UII) is the most potent mammalian vasoconstrictor identified so far. Our previous study showed that UII is a potent mitogen of airway smooth muscle cells (ASMC) inducing ASMC proliferation in a dose-dependent manner. The signal transduction pathway of UII mitogenic effect remains to be cl...

journal_title：Chinese medical journal

authors： Chen YH,Zhao MW,Yao WZ,Pang YZ,Tang CS

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Recent studies have suggested that cancer stem cells cause tumor recurrence based on their resistance to radiotherapy and chemotherapy. Although the highly invasive nature of glioblastoma cells is also implicated in the failure of current therapies, it is not clear whether cancer stem cells are involved in i...

journal_title：Chinese medical journal

authors： Yu SP,Yang XJ,Zhang B,Ming HL,Chen C,Ren BC,Liu ZF,Liu B

更新日期：2011-09-01 00:00:00

abstract：Background:Myoclonic epilepsy with ragged red fibers (MERRF) syndrome is characterized by myoclonus, generalized epilepsy, cerebellar ataxia, and ragged red fibers (RRFs) in the muscle. T-to-C transition at nucleotide position 14709 in the mitochondrial tRNA glutamic acid (tRNAGlu) gene has previously been associated w...

journal_title：Chinese medical journal

authors： Ban R,Guo JH,Pu CQ,Shi Q,Liu HX,Zhang YT

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The offspring of women with gestational diabetes mellitus (GDM) are prone to macrosomia. However, birth weight is difficult to be correctly estimated by ultrasound because of fetal asymmetric growth characteristics. This study aimed to investigate the correlations between fetal hemodynamics, fetal growth ind...

journal_title：Chinese medical journal

authors： Liu F,Liu Y,Lai YP,Gu XN,Liu DM,Yang M

更新日期：2016-09-05 00:00:00

abstract：OBJECTIVE:To investigate the use of the Gibbs-Sampler method in evaluating the relationship between clinic events and health risks in a meta-analysis of multiple clinical trials. METHODS:By using a generalized linear model with random-effects, Gibbs-Sampler technique was used in a meta-analysis of multiple clinical tr...

journal_title：Chinese medical journal

authors： Wang Y,Wang Y,Li L,Wang Z,Macus F,Salim Y

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Nowadays, there is a remarkable rise in resectability rate of periampullary adenocarcinoma and the mortality and morbidity of the pancreaticoduodenectomy procedure have been reduced remarkably, while the 5 year survival rates of patients with carcinoma of the head of the pancreas are still below 25%. We cond...

journal_title：Chinese medical journal

authors： Yang YM,Wan YL,Tian XD,Zhuang Y,Huang YT

更新日期：2005-11-20 00:00:00

abstract：BACKGROUND:Congenital uterine anomalies are associated with the highest incidence of reproductive failure and obstetric complications. This study aimed to summarize the clinical characteristics and prenatal outcome of pregnancy in women with congenital uterine malformations. METHODS:This retrospective study evaluated ...

journal_title：Chinese medical journal

authors： Zhang Y,Zhao YY,Qiao J

更新日期：2010-02-20 00:00:00

abstract：BACKGROUND:Occult stress urinary incontinence may lead to de novo stress urinary incontinence after pelvic floor repair surgery. A measurement of pudendal nerve terminal motor latency can reflect the integrity of the nerves. We aimed to explore the value of pudendal nerve terminal motor latency in the diagnosis of occu...

journal_title：Chinese medical journal

authors： Zhu L,Hai N,Lang JH,Yu SY,Li B,Wong F

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:In many studies, obstructive sleep apnea (OSA) has been shown to be an independent risk factor for cardiovascular disease. Conversely, there are few reports establishing possible relation between OSA and venous thromboembolism (VTE). In this study, the aim is to evaluate OSA via polysomnography in patients w...

journal_title：Chinese medical journal

authors： Kezban OS,Ali NA,Umran T,Talha D,Ege GB,Peri A,Leyla YA,Hasan S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Glucocorticoid is speculated to be able to have Aspergillus fumigatus (A. fumigatus) being more susceptible to reactive oxygen species (ROS) by inhibiting Afyap1, the transcription factor activating protein-1 (AP-1) homologue in A. fumigatus, which may provide a clue to expand the clinical use of glucocortic...

journal_title：Chinese medical journal

authors： Xu H,Li LJ,Wan Z,Li RY,Liu W

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomida...

journal_title：Chinese medical journal

authors： Tan HY,Sun LN,Wang XL,Ye TH

更新日期：2010-03-20 00:00:00

abstract：OBJECTIVE:To study the expression of vascular endothelial growth factor (VEGF) in different parts of heart during early acute myocardial ischemia. METHODS:The expression of VEGF in control and study group in rats was performed with the Strept Avidin-Biotin-Peroxidase Complex (SABC) method. RESULTS:A rapid expression ...

journal_title：Chinese medical journal

authors： Chen J,Xu X,Wu X,Zhu J

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To analyze the relationship between the proto-oncogene c-fos change and neuronal degeneration in the hippocampus of the patients with Alzheimer's disease. METHODS:The post mortem human hippocampal tissues were divided into three groups, namely, the aged, the young and Alzheimer's disease (AD) groups. Each gr...

journal_title：Chinese medical journal

authors： Lu W,Mi R,Tang H,Liu S,Fan M,Wang L

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The hyperdynamic circulatory state in end-stage liver disease is similar to the hemodynamic state in endotoxic shock. Recent research indicated that proper use of norepinephrine (NE) in patients with endotoxic shock could improve the perfusion of visceral organs and raise the survival rate. In this study, do...

journal_title：Chinese medical journal

authors： Zhang LP,Li M,Yang L

更新日期：2005-12-05 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a common primary cancer frequently associated with hepatitis B virus (HBV) infection. However, whether these identified genes are particularly associated with HBV-related HCC remains unknown. The aim of this study was to investigate the differential gene expression between H...

journal_title：Chinese medical journal

authors： Huang YK,Fan XG,Qiu F,Wang ZM

更新日期：2011-07-05 00:00:00

abstract：:The ultrastructural changes of chronic cardiopathy in diabetic biobreeding rats were observed electronmicroscopically. The thickness of the myocardial capillary basement membrane (CBM) and volume fraction of myofilaments in the myocardium were quantitatively measured with a video interactive display system III (VIDS-I...

journal_title：Chinese medical journal

authors： Zhou XP,Zhong XL,Zhu XX,Zhong CS,Yu YF

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Screening for amblyopia at earliest is important for early treatment and better prognosis. This study aimed to evaluate the validity of uncorrected distant and near visual acuity (VA) and stereoacuity for screening amblyopia in grade-1 students in primary school in central China. METHODS:By stratified clust...

journal_title：Chinese medical journal

authors： Fu J,Li SM,Li JL,Li SY,Liu LR,Wang Y,Li H,Zhu BD,Ji YZ,Yang Z,Li L,Chen W,Wang NL,g Childhood Eye Study Group.

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To analyse the relationship between age and treatment with captopril after acute myocardial infarction (AMI). METHODS:In a randomized trial, 822 patients with a first AMI received conventional medical treatment, including intravenous thrombolytic therapy and oral aspirin or metoprolol, and then were randomly...

journal_title：Chinese medical journal

authors： Cai X,Shen W,Gong L

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The anterior cruciate ligament (ACL) is one of the most commonly injured knee ligaments. Even following ACL reconstruction, significant articular cartilage degeneration can be observed and most patients suffer from premature osteoarthritis. Articular cartilage degeneration and osteoarthritis development afte...

journal_title：Chinese medical journal

authors： Shi DL,Wang YB,Ai ZS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Recently, conservative surgery is acceptable in young patients with borderline ovarian tumor and ovarian cancer. The preservation of these patients' future fertility has been the focus of recent interest. This study aimed to observe the effect of gonadotropin-releasing hormone agonists (GnRHa) cotreatment du...

journal_title：Chinese medical journal

authors： Zhu HL,Wang Y,Li XP,Wang CH,Wang Y,Cui H,Wang JL,Wei LH

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence rate, pathologic changes, mechanisms and diagnostic methods in renal bone disease. METHODS:The blood levels of carboxyterminal parpthyriod hormone (C-PTH), 1,25(OH)2D3, calcium and phosphate, aluminum in serum and bone tissue were measured. The bone biopsy and bone scan with 99m ...

journal_title：Chinese medical journal

authors： Zhu P,Wang G,Yu Y,Lou D,Wang S,Jia J,Dong D

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Our previous studies have shown that both apoptosis and necrosis are involved in hair cell (HC) pathogenesis in aging cochleae. To better understand the biological mechanisms responsible for the regulation of HC death, we examined the activity of succinate dehydrogenase (SDH), a mitochondrial bioenergetic en...

journal_title：Chinese medical journal

authors： Yang WP,Hu BH,Sun JH,Zhai SQ,Henderson D

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:At the end of 2005, 650,000 people lived with human immunodeficiency virus type-1 (HIV-1) in China, of whom 75 000 were AIDS patients. Many AIDS patients received highly active antiretroviral therapy (HAART) supported by the "China CARES" program but the immune responses of HAART were seldom reported. This s...

journal_title：Chinese medical journal

authors： Zhang ZN,Shang H,Jiang YJ,Liu J,Dai D,Diao YY,Geng WQ,Jin X,Wang YN

更新日期：2006-12-05 00:00:00

abstract：:By employing monoclonal phosphorylated neurofilaments antibody, we studied the abnormally pale-staining neurons in 3 cases of corticonigral degeneration by the avidin-biotin immunoperoxidase method. For comparison, the central chromatolysis in anterior horn cells secondary to cervical spine fracture and "ballooned" ne...

journal_title：Chinese medical journal

authors： Wang LN,Kowall NW,Richardson EP Jr

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and features of active human cytomegalovirus (HCMV) infection in children with systemic lupus erythematosus (SLE) and evaluate the diagnostic value of the HCMV using antigenemia assay, serum polymerase chain reaction (PCR) and serology test. METHODS:Twenty-one SLE children under...

journal_title：Chinese medical journal

authors： Zhang C,Shen K,Jiang Z,He X

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To get a more comprehensive recognition about carpal tunnel syndrome (CTS), especially the manual housework as its risk factor, and to facilitate early diagnosis and proper treatment. METHODS:262 CTS patients (396 CTS hands) were analyzed retrospectively. A 1:1 matched case-control study of 61 woman pairs i...

journal_title：Chinese medical journal

authors： Tang X,Zhuang L,Lu Z

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:To assess the feasibility and efficacy of eliciting leukemia-specific T-cell responses in syngeneic mice in vitro and in vivo using dendritic cells (DCs) pulsed with total RNA from leukemia cells. METHODS:DCs generated from bone marrow culture in vitro in the presence of combined cytokines were pulsed with ...

journal_title：Chinese medical journal

authors： Li M,You S,Ge W,Ma S,Ma N,Zhao C

更新日期：2003-11-01 00:00:00

abstract：:The effect of exercise on pulmonary gas exchange, arterial oxygenation, oxygen transport and delivery, and hemodynamics are studied in 100 patients with chronic obstructive pulmonary diseases. According to the change of PaO2 or PaCO2 induced by exercise, patients were divided into two groups. Group A (n = 52) had sign...

journal_title：Chinese medical journal

authors： Zeng GB,Zhang ZX,Xu YJ,Duan SF

更新日期：1992-01-01 00:00:00