Activation and coreceptor expression of T lymphocytes induced by highly active antiretroviral therapy in Chinese HIV/AIDS patients.

abstract：BACKGROUND:After establishing a murine model of aminoglycoside antibiotic (AmAn) induced ototoxicity, the sensitivity of AmAn induced ototoxicity in three murine strains and the effect of kanamycin on the expression of Na-K-2Cl cotransporter-1 (NKCC1) in stria vascularis were investigated. METHODS:C57BL/6J, CBA/CaJ, N...

journal_title：Chinese medical journal

authors： Chu HQ,Xiong H,Zhou XQ,Han F,Wu ZG,Zhang P,Huang XW,Cui YH

更新日期：2006-06-20 00:00:00

abstract：BACKGROUND:Increasing prevalence of Staphylococcus aureus (S. aureus), particularly methicillin-resistant S. aureus (MRSA) has been reported in China. In this study, we investigated the drug resistance characteristic, genetic background, and molecular epidemiological characteristic of S. aureus in Changsha. METHODS:Be...

journal_title：Chinese medical journal

authors： Zou MX,Zhou RR,Wu WJ,Zhang NJ,Liu WE,Hu FP,Fan XG

更新日期：2012-07-01 00:00:00

abstract：Background:Type 2 diabetes (T2DM) patients are susceptible to Helicobacter pylori (HP), and it has been reported that the occurrence of proteinuria is associated with HP infection in T2DM patients; however, this view remains controversial. This meta-analysis aimed to explore the association between HP infection and the...

journal_title：Chinese medical journal

authors： Shi Y,Duan JY,Liu DW,Qiao YJ,Han QX,Pan SK,Tang L,Cai GY,Chen XM,Liu ZS,Zhu HY

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Trocar-site hernia (TSH) is a serious complication after laparoscopic procedures. Although it is a rare entity, it can have life-threatening consequences. This study aimed to retrospectively analyze the potential associated factors for TSH following gynecologic laparoscopy and summarize prevention strategies...

journal_title：Chinese medical journal

authors： Zhu YP,Liang S,Zhu L,Sun ZJ,Lang JH

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Functional neuroimaging study has opened an avenue for exploring the pathophysiology of cluster headache (CH). The aim of our study was to assess the changes in brain activity in CH patients by the regional homogeneity method using resting-state functional magnetic resonance imaging technique. METHODS:The f...

journal_title：Chinese medical journal

authors： Qiu EC,Yu SY,Liu RZ,Wang Y,Ma L,Tian LX

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Tuberous sclerosis (TS) is an autosomal dominant disorder with a significant range of clinical expressions. The involvement of vital organs, such as the brain, kidney, heart and lung is the main cause of death in patients with TS. The aim of this study is to summarize the characteristic cutaneous features an...

journal_title：Chinese medical journal

authors： Sun XF,Yan CL,Fang L,Shen FM,Liao KH

更新日期：2005-02-05 00:00:00

abstract：BACKGROUND:Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric carcinoma, which has its unique clinicopathological features and poorer prognosis than that of the ordinary gastric adenocarcinoma. At present, there is still a lack of understanding about this disease. The current study aimed to summariz...

journal_title：Chinese medical journal

authors： Zhang JF,Shi SS,Shao YF,Zhang HZ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Prediabetes is an early stage of β-cell dysfunction presenting as insulin resistance. Evidences suggest that endoplasmic reticulum (ER) stress is involved in the pathogenesis of type 2 diabetes mellitus and prediabetes. In a Chinese population with prediabetes, we investigated single nucleotide polymorphisms...

journal_title：Chinese medical journal

authors： Feng N,Ma X,Wei X,Zhang J,Dong A,Jin M,Zhang H,Guo X

更新日期：2014-01-01 00:00:00

abstract：:The extent of participation and changes of glycophorins (GPs) and membrane proteins in the merozite-human erythrocyte interaction during the invasion of Plasmodium falciparum (Pf) were studied by immunoblotting techniques. Polyclonal antisera to alpha GP and to its C-terminal fragment (residues 82-131) as well as M an...

journal_title：Chinese medical journal

authors： Liu JF,Lu YQ,Roth EF Jr,Nagel RL,Blumenfeld OO

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Lidocaine and ropivacaine are often combined in clinical practice to obtain a rapid onset and a prolonged duration of action. However, the systemic toxicity of their mixture at different concentrations is unclear. This study aimed to compare the systemic toxicity of the mixture of ropivacaine and lidocaine a...

journal_title：Chinese medical journal

authors： Wan QX,Bo YL,Li HB,Li WZ

更新日期：2010-01-05 00:00:00

abstract：BACKGROUND:Benign prostate hyperplasia is one of the most common diseases affecting the health of the aging males. Watchful waiting is an acceptable management strategy for benign prostate hyperplasia in which the patient is monitored by the physician but receives no active intervention. The epidemiological data on thi...

journal_title：Chinese medical journal

authors： Wu SL,Li NC,Xiao YX,Jin J,Qiu SP,Ye ZQ,Kong CZ,Sun G,Na YQ

更新日期：2006-12-20 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a severe disease in critically ill patients. Neutrophil infiltration into kidney was associated with the development of AKI, and P-selectin may be involved in the process of neutrophil recruitment in kidney. This study aimed to explore the potential effect of platelet-derived P-s...

journal_title：Chinese medical journal

authors： Li XH,Qian YB,Meng XX,Wang RL

更新日期：2017-07-20 00:00:00

abstract：BACKGROUND:The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients. METHODS:The study subjects were 49 cancer patients (1.4%) out of 3448 end stage renal disease...

journal_title：Chinese medical journal

authors： Zhou L,Cao YL,Li WG,Fu FT,Zhang L,Wang X,Shi XH

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To study the changes of creatine kinase MM (CK-MM) isoforms in Duchenne muscular dystrophy (DMD) patients. METHODS:Serum samples from 49 DMD patients and 40 control subjects were collected for CK-MM isoforms measurement. CK-MM isoforms were separated within 30 minutes by electrophoresis on agarose gel with a...

journal_title：Chinese medical journal

authors： Zhao X,Bi C,Yang Z

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Dynesys dynamic stabilization system was first implanted in patients in 1994, and introduced to China in 2007. Therefore, it was a new technique for Chinese orthopedics and hence necessary to collect clinical data about Dynesys in China. The objective of this study was to report the preliminary results of Dy...

journal_title：Chinese medical journal

authors： Li HP,Li F,Guan K,Zhao GM,Shan JL,Sun TS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The usual transbronchial coagulation techniques include microwave, argon plasma coagulation (APC), electrocautery and cryotherapy. However, there are serious clinical problems in the safety of each. By analyzing the experimental data and clinical observations, we observed the variable effects of different co...

journal_title：Chinese medical journal

authors： Bai C,Dong YC,Song XL,Huang Y,Shi H,Hu ZL,Li Q

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Angiogenesis and lymphogenesis which were promoted by vascular endothelial growth factor (VEGF) and VEGF-C are important in the growth and metastasis of solid tumors. The high level of VEGF and VEGF-C were distributed in numerous types of cancers, but their distribution and expression in Wilms tumor, the mos...

journal_title：Chinese medical journal

authors： Wang L,Zhang D,Chen XR,Fan YX,Wang JX

更新日期：2011-11-01 00:00:00

abstract：:Pleomorphic xanthoastrocytoma (PXA) is a rare benign tumor that is usually located in the superficial cerebral hemisphere. Most reports of PXAs have included only a single case or small series. Therefore, the data with respect to the natural history of this tumor are fragmentary. We report a case of a PXA in the unusu...

journal_title：Chinese medical journal

authors： Yang WQ,Huang B,Liang CH

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To explore the methods of lens-sparing (without lensectomy), non-silicone oil tamponade and no scleral buckling for treatment of early giant retinal tears. METHODS:Thirteen cases of early retinal detachment of proliferative vitreoretinopathy (PVR) grade C2-D1, with giant tear extending from 135 degrees to 27...

journal_title：Chinese medical journal

authors： Xu X,Zhang X,Wu N,Ho PC

更新日期：1999-03-01 00:00:00

abstract：:The protective effect of improving the microcirculation on the retinal ganglion cells (RGC) and the ultrastructure of the optic nerve after intravenous (i.v.) use of Salviae miltiorrhiza (SMR) was studied in a chronic intraocular hypertension model in 36 rabbits. These rabbits were treated with topical 0.5% timolol, o...

journal_title：Chinese medical journal

authors： Zhu MD,Cai FY

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated increased functions of osteoblasts on nanophase materials compared to conventional ceramics or composites. Nanophase materials are unique materials that simulate dimensions of constituent components of bone as they possess particle or grain sizes less than 100 nm. However, ...

journal_title：Chinese medical journal

authors： Han P,Ji WP,Zhao CL,Zhang XN,Jiang Y

更新日期：2011-01-01 00:00:00

abstract：Background:Recent advances in extracorporeal membrane oxygenation (ECMO) have led to increasing interest in its use during cardiopulmonary resuscitation (CPR). However, decisions regarding extracorporeal CPR (ECPR) in children are difficult as a result of limited studies, especially in Asia Pacific. The objective of th...

journal_title：Chinese medical journal

authors： Chen GL,Qiao YR,Ma JH,Wang JX,Hei FL,Yu J

更新日期：2018-06-20 00:00:00

abstract：:The persistence of anti-HBs was investigated in 95 juveniles who received plasma-derived HBV vaccine (vaccine group) and 63 counterparts who got anti-HBs from natural HBV infection (infection group) for a period of five years. The positive rates of anti-HBs from the first to fifth year in the vaccine group are 97.89%,...

journal_title：Chinese medical journal

authors： Zhang MT,Liu KZ,Jin JH,Ding LM,Zhou SC,Yu QY,Zhang XZ

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Marked interindividual variation exists in blood pressure response to benazepril, which is considered to have genetic basis. Our objectives were to evaluate whether the E112D polymorphism in the prolylcarboxypeptidase (PRCP) gene has impact on blood pressure response to benazepril. METHODS:Hypertensive pati...

journal_title：Chinese medical journal

authors： Zhang Y,Hong XM,Xing HX,Li JP,Huo Y,Xu XP

更新日期：2009-10-20 00:00:00

abstract：BACKGROUND:In vivo quantification of choroidal neovascularization (CNV) based on noninvasive optical coherence tomography (OCT) examination and in vitro choroidal flatmount immunohistochemistry stained of CNV currently were used to evaluate the process and severity of age-related macular degeneration (AMD) both in huma...

journal_title：Chinese medical journal

authors： Nie C,Zhang MN,Zhao HW,Olsen TD,Jackman K,Hu LN,Ma WP,Chen XF,Wang J,Zhang Y,Gao TS,Uehara H,Ambati BK,Luo L

更新日期：2015-06-05 00:00:00

abstract：BACKGROUND:Wolf-Hirschhorn syndrome (WHS) is a contiguous gene syndrome that is typically caused by a deletion of the distal portion of the short arm of chromosome 4. However, there are few reports about the features of Chinese WHS patients. This study aimed to characterize the clinical and molecular cytogenetic featur...

journal_title：Chinese medical journal

authors： Yang WX,Pan H,Li L,Wu HR,Wang ST,Bao XH,Jiang YW,Qi Y

更新日期：2016-03-20 00:00:00

abstract：BACKGROUND:The cell layer of the ciliary epithelium is responsible for aqueous humor secretion and maintenance. Ion channels play an important role in these processes. The main aim of this study was to determine whether the well-characterized members of the Kv1 family (Kv1.3) contribute to the Kv currents in ciliary ep...

journal_title：Chinese medical journal

authors： Li YF,Zhuo YH,Bi WN,Bai YJ,Li YN,Wang ZJ

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:Glucocorticoid is speculated to be able to have Aspergillus fumigatus (A. fumigatus) being more susceptible to reactive oxygen species (ROS) by inhibiting Afyap1, the transcription factor activating protein-1 (AP-1) homologue in A. fumigatus, which may provide a clue to expand the clinical use of glucocortic...

journal_title：Chinese medical journal

authors： Xu H,Li LJ,Wan Z,Li RY,Liu W

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Development of vulnerable lesions is not limited to the target lesions, but a pan-coronary process. Such lesions are identified by positive remodeling (intravascular ultrasound (IVUS) and complex lesions (angiography)). The prevalence of lesions with vulnerable characteristics in patients with stable angina ...

journal_title：Chinese medical journal

authors： Sun L,Lü SZ,Jin ZN,Song XT

更新日期：2010-04-05 00:00:00

abstract：BACKGROUND:There are controversies about the use of artificial colloids. This research was aimed to determine the effect of various artificial colloids on blood coagulation in the shock stage of severe burn injury. METHODS:Totally, 18 female Ba-Ma mini-pigs were subjected to a 40% total body surface third-degree flame...

journal_title：Chinese medical journal

authors： Zhou JJ,Xing N,Chen J,Shi JW,Su GL

更新日期：2013-01-01 00:00:00