Effects of exercise on pulmonary gas exchange and oxygen transport in chronic obstructive pulmonary diseases.

Abstract:

:The effect of exercise on pulmonary gas exchange, arterial oxygenation, oxygen transport and delivery, and hemodynamics are studied in 100 patients with chronic obstructive pulmonary diseases. According to the change of PaO2 or PaCO2 induced by exercise, patients were divided into two groups. Group A (n = 52) had significantly increased of PaO2 with little change in PaCO2. Mixed venous PO2, oxygen transport and coefficient of oxygen delivery decreased while the alveolar-arterial PO2 gradients and venous admixture increased significantly in Group B as compared with these parameters in Group A during exercise. Our data imply that exercise may lead to marked deterioration of pulmonary gas exchange, arterial oxygenation, oxygen transport and hemodynamic abnormalities in patients in whom PaO2 is decreased during exercise.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Zeng GB,Zhang ZX,Xu YJ,Duan SF

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

49-54

issue

1

eissn

0366-6999

issn

2542-5641

journal_volume

105

pub_type

杂志文章
  • Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid.

    abstract:BACKGROUND:CD4(+)CD25(+) regulatory T cells (Tregs) mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), and transforming growth factor beta (TG...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang Q,Qian FH,Liu H,Zhou LF,Huang M,Zhang XL,Yin KS

    更新日期:2008-02-05 00:00:00

  • Quantification of plasma DNA as a screening tool for lung cancer.

    abstract:BACKGROUND:Recent studies suggest that circulating DNA may be a potential tumor marker for lung cancer, but most of these studies are conducted between healthy controls and lung cancer patients, with few or no benign lung disease patients included. The objective of this study was to evaluate the performance of plasma D...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xie GS,Hou AR,Li LY,Gao YN,Cheng SJ

    更新日期:2004-10-01 00:00:00

  • Electromyographic monitoring of facial nerve under different levels of neuromuscular blockade during middle ear microsurgery.

    abstract:BACKGROUND:The evoked electromyography (EMG) is frequently used to identify facial nerve in order to prevent its damage during surgeries. Partial neuromuscular blockade (NMB) has been suggested to favor EMG activity and insure patients' safety. The aim of this study was to determine an adequate level of NMB corresponde...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Cai YR,Xu J,Chen LH,Chi FL

    更新日期:2009-02-05 00:00:00

  • Rationale and study design for one-stop assessment of renal artery stenosis and renal microvascular perfusion with contrast-enhanced ultrasound for patients with suspected renovascular hypertension.

    abstract:BACKGROUND:Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000002

    authors: Ren JH,Ma N,Wang SY,Sun YJ,Zhang YW,Guo FJ,Li YJ,Li TH,Ai H,Zhang WD,Li P,Ma WH

    更新日期:2019-01-05 00:00:00

  • Recurrent Septic Pulmonary Embolism Related to an Implanted Central Venous Access Port Device.

    abstract:: ...

    journal_title:Chinese medical journal

    pub_type: 信件

    doi:10.4103/0366-6999.247196

    authors: Hong G,Kim YS

    更新日期:2018-12-20 00:00:00

  • A survey on the attitudes of doctors towards health insurance payment in the medical consortium.

    abstract:BACKGROUND:Medical consortium is a specific vertical integration model of regional medical resources. To improve medical resources utilization and control the health insurance costs by fee-for-service plans (FFS), capitation fee and diagnosis-related groups (DRGs), it is important to explore the attitudes of doctors to...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Shi G,Wu T,Xu WG

    更新日期:2011-01-01 00:00:00

  • Subclavian steal syndrome: report of 28 cases.

    abstract:OBJECTIVE:To study the experience in the treatment of subclavian steal syndrome (SSS) and the relation between SSS and the damage of brain. METHODS:In 28 patients with SSS, 23 were operated on. They complained of vertigo, TIA, and claudication of arms. One patient suffered from severe stem ischemia spasm. All the pati...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Guan H,Liu C,Yu Z

    更新日期:1999-11-01 00:00:00

  • Clinical study on the thrombolytic effect with different doses of urokinase in acute myocardial infarction. The Collaborative Research Group on Thrombolysis.

    abstract:OBJECTIVE:To investigate the effects of different doses of intravenous domestic urokinase. METHODS:One thousand and twenty three cases of acute myocardial infarction within 6 hours after acute onset were divided randomly into two groups with 539 cases in the low dose group (urokinase 22,000IU/kg, total dose not lower ...

    journal_title:Chinese medical journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors:

    更新日期:1997-01-01 00:00:00

  • Resveratrol induces apoptosis in pancreatic cancer cells.

    abstract:BACKGROUND:Pancreatic cancer is one of the most lethal human cancers with a very low survival rate of 5 years. Conventional cancer treatments including surgery, radiation, chemotherapy or combinations of these show little effect on this disease. Several proteins have been proved critical to the development and the prog...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou JH,Cheng HY,Yu ZQ,He DW,Pan Z,Yang DT

    更新日期:2011-06-01 00:00:00

  • MicroRNA 145 may play an important role in uveal melanoma cell growth by potentially targeting insulin receptor substrate-1.

    abstract:BACKGROUND:MicroRNAs (miRNAs) contribute to tumorigenesis by acting as either oncogenes or tumor suppressor genes. In this study, we investigated the role of miR-145 in the pathogenesis of uveal melanoma. METHODS:Expression profiles of miRNAs in uveal melanoma were performed using Agilent miRNA array. Quantitative rea...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li Y,Huang Q,Shi X,Jin X,Shen L,Xu X,Wei W

    更新日期:2014-01-01 00:00:00

  • Impact of Baseline Bleeding Risk on Efficacy and Safety of Ticagrelor versus Clopidogrel in Chinese Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

    abstract:Background:There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS). We considered that the baseline bleeding risk might be an undetected key factor that significantly affected the efficacy of ticagrelor. Methods:A total of...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.239306

    authors: Wang HY,Li Y,Xu XM,Li J,Han YL

    更新日期:2018-09-05 00:00:00

  • An uncontrolled open-label, multicenter study to monitor the antiviral activity and safety of inhaled zanamivir (as Rotadisk via Diskhaler device) among Chinese adolescents and adults with influenza-like illness.

    abstract:BACKGROUND:It is the first multicenter clinical study in China to investigate zanamivir use among Chinese adolescents and adults with influenza-like illness (ILI) since 2009, when inhaled zanamivir (RELENZA(®)) was marketed in China. METHODS:An uncontrolled open-label, multicentre study to evaluate the antiviral activ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Cao B,Wang DY,Yu XM,Wei LQ,Pu ZH,Gao Y,Wang J,Dong JP,Li XL,Xu Q,Hu K,Chen BY,Yu YS,Song SF,Shu YL,Wang C

    更新日期:2012-09-01 00:00:00

  • Efficacy and safety of domestic leuprorelin in girls with idiopathic central precocious puberty: a multicenter, randomized, parallel, controlled trial.

    abstract:BACKGROUND:In central precocious puberty (CPP), the pulse secretion and release of gonadotropin-releasing hormone (GnRH) are increased due to early activation of the hypothalamic-pituitary-gonadal axis, resulting in developmental abnormalities with gonadal development and appearance of secondary sexual characteristics....

    journal_title:Chinese medical journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.4103/0366-6999.156773

    authors: Li WJ,Gong CX,Guo MJ,Xing J,Li T,Song WH,Luo XP,Wu D,Liang JP,Cao BY,Gu Y,Su C,Liang XJ,Liu M,Wang R,Li FT

    更新日期:2015-05-20 00:00:00

  • Characteristics of coronary microvascular lesions in autopsied elderly with hypertensive left ventricular hypertrophy.

    abstract:OBJECTIVE:To observe the characteristics of coronary microvascular lesions (CML) in the autopsied elderly cases with hypertensive left ventricular hypertrophy (LVH) and the difference of CML among the groups of essential hypertension (EHT), coronary heart disease (CHD) and diabetes (NIDDM) also with LVH. METHODS:A ret...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li X,Li R,Yu W,Shi H,Wei L

    更新日期:2002-05-01 00:00:00

  • Menopausal Symptoms and Sleep Quality During Menopausal Transition and Postmenopause.

    abstract:BACKGROUND:Menopausal symptoms and sleep difficulty were physiological processes that were affected by genetic and other factors. This study was to investigate the prevalence of menopausal symptoms and sleep quality in menopausal transition (MT) and postmenopause (PM) women in Taiyuan, Shanxi. METHODS:A community-base...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.178961

    authors: Zhang JP,Wang YQ,Yan MQ,Li ZA,Du XP,Wu XQ

    更新日期:2016-04-05 00:00:00

  • Myoglobin over-expression attenuates angiogenic response in hindlimb ischemia in mice.

    abstract:BACKGROUND:Myoglobin is expressed exclusively in striated skeletal muscles and has been implicated in nitric oxide scavenging. Accumulating data suggest a critical role for nitric oxide in both the endogenous and therapeutic angiogenic response to ischemia. A clear role for myoglobin in ischemic skeletal muscle is unce...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yang YG,Guan H,Liu CW,Li YJ

    更新日期:2009-05-05 00:00:00

  • Lactadherin and procoagulant activities of red blood cells in cyclosporine induced thrombosis.

    abstract:BACKGROUND:The side effects of cyclosporine therapy include thromboembolic complications. However, the mechanisms underlying the hypercoagulable state induced by cyclosporine are not fully understood. Cyclosporine binds to red blood cells (RBCs) with a high affinity in circulation and alters the membranes of RBCs. Ther...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zheng YN,Yu HJ,Hou JX,Lu CF,Zhou J

    更新日期:2009-07-20 00:00:00

  • Enteric transmission of transfusion-transmitted virus.

    abstract:OBJECTIVE:To detect the virus in the feces and sera of patients in an outbreak of enterically transmitted non-A, non-E hepatitis, and this review covers the epidemiologic features and experimental infection of this novel virus. DATA SOURCES:Data sources come from our own work on this subject, published and unpublished...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Luo K,Zhang L

    更新日期:2001-11-01 00:00:00

  • Effect of etomidate on voltage-dependent potassium currents in rat isolated hippocampal pyramidal neurons.

    abstract:BACKGROUND:Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomida...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Tan HY,Sun LN,Wang XL,Ye TH

    更新日期:2010-03-20 00:00:00

  • Diagnostic Value of Sensitive Biomarkers for Early Kidney Damage in Diabetic Patients with Normoalbuminuria.

    abstract:: ...

    journal_title:Chinese medical journal

    pub_type: 信件

    doi:10.4103/0366-6999.246080

    authors: Zhang D,Han QX,Wu MH,Shen WJ,Yang XL,Guo J,Pan SK,Liu ZS,Tang L,Cai GY,Chen XM,Zhu HY

    更新日期:2018-12-05 00:00:00

  • Effect of homocysteine on plaque formation and oxidative stress in patients with acute coronary syndromes.

    abstract:BACKGROUND:Cardiovascular diseases, especially coronary artery disease (CAD), are major causes of death in industrialized countries. Elevated concentrations of plasma homocysteine (Hcy) have been associated with an increased risk of CAD. Increased plasma levels of chemokine, characterized by their ability to induce mig...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang G,Mao JM,Wang X,Zhang FC

    更新日期:2004-11-01 00:00:00

  • Dynamic infusion cavernosometry and cavernosography for classifying venous erectile dysfunction and its significance for individual treatment.

    abstract:BACKGROUND:The precise pathophysiology of venous erectile dysfunction (VED) was still unclear. Dynamic infusion cavernosometry and cavernosography (DICC) was the gold standard approach for the diagnoses of VED. However, a standard operative procedure of DICC was needed and it was unclear whether DICC could show promise...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000099

    authors: Gao QQ,Chen JH,Chen Y,Song T,Dai YT

    更新日期:2019-02-01 00:00:00

  • Immunoglobulin G subclass deficiency in children with recurrent respiratory tract infections.

    abstract::With monoclonal antibodies serum immunoglobulin G(IgG) subclasses were measured in seventy children aged 2 to 13 years with recurrent respiratory tract infections including upper respiratory tract infections, otitis media, sinusitis, asthmatic bronchitis and pneumonia. 211 healthy, aged-matched children served as cont...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Jiang LP,Yang XQ,Li CR,Zhang YW,Wang LJ,Shen J

    更新日期:1991-02-01 00:00:00

  • Pretreatment with repeated electroacupuncture attenuates transient focal cerebral ischemic injury in rats.

    abstract:OBJECTIVE:To investigate whether pretreatment with repeated electroacupuncture (EA) at the Baihui acupoint could induce ischemic tolerance against transient focal cerebral ischemic injury in rats. METHODS:Thirty male Sprague-Dawley (SD) rats were randomly divided into 3 groups (n=10 for each): the control group consis...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xiong L,Lu Z,Hou L,Zheng H,Zhu Z,Wang Q,Chen S

    更新日期:2003-01-01 00:00:00

  • Diffusion tensor imaging-derived measures of fractional anisotropy across the pyramidal tract are influenced by the cerebral hemisphere but not by gender in young healthy volunteers: a split-plot factorial analysis of variance.

    abstract:BACKGROUND:Diffusion tensor imaging (DTI) permits quantitative examination within the pyramidal tract (PT) by measuring fractional anisotropy (FA). To the best of our knowledge, the inter-variability measures of FA along the PT remain unexplained. A clear understanding of these reference values would help radiologists ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Roldan-Valadez E,Rios-Piedra E,Favila R,Alcauter S,Rios C

    更新日期:2012-06-01 00:00:00

  • CT features of colloid carcinomas of the pancreas.

    abstract:BACKGROUND:Colloid carcinomas of the pancreas have better prognosis than ordinary ductal adenocarcinoma, and preoperative distinction of colloid carcinoma from other pancreatic tumors is valuable for patient therapeutic planning and prognosis assessment. However, data about CT features of colloid carcinoma are very lim...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ren FY,Shao CW,Zuo CJ,Lu JP

    更新日期:2010-05-20 00:00:00

  • Effects of rhubarb on the expression of glucocorticoids receptor and regulation of cellular immunity in burn-induced septic rats.

    abstract:BACKGROUND:It is important to modulate the expression of glucocorticoids receptor (GR) in tress and maintain the immunity homeostasis in sepsis process. Rhubarb have been shown to have potential effects on anti-inflammatory and immune modulation. The present study was designed to investigate the effects of rhubarb on t...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000201

    authors: Liu J,Li G,Chen YZ,Zhang LD,Wang T,Wen ZL,Wang L,Chen DC

    更新日期:2019-05-20 00:00:00

  • Clinical results of combined palliative procedures for cyanotic congenital heart defects with intractable hypoplasia of pulmonary arteries.

    abstract:BACKGROUND:Congenital heart defects with intractable hypoplasia of the pulmonary arteries without intercourse or with intercourse stenosis is unsuitable for surgical correction or regular palliative procedures. We reported our experience with combined palliative procedures for congenital heart defects with intractable ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Fan XM,Zhu YB,Su JW,Zhang J,Li ZQ,Xu YQ,Li XF,Liu YL

    更新日期:2013-01-01 00:00:00

  • Changes of negative charge on RBC and glomeruli and its relation to the proteinuria of adriamycin nephrosis in rats.

    abstract::The depth and area-percentage of Alcian blue (AB) staining of glomeruli, the ability of RBC to bind AB and the onset of proteinuria in adriamycin nephrosis in rats were studied. The results showed that the negative charge (NC) on RBC and glomeruli decreased significantly after injection of adriamycin and there was a p...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen ZY,Jiang XY

    更新日期:1991-07-01 00:00:00

  • Incubation and application of transgenic green fluorescent nude mice in visualization studies on glioma tissue remodeling.

    abstract:BACKGROUND:The primary reasons for local recurrence and therapeutic failure in the treatment of malignant gliomas are the invasion and interactions of tumor cells with surrounding normal brain cells. However, these tumor cells are hard to be visualized directly in histopathological preparations, or in experimental glio...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Dong J,Dai XL,Lu ZH,Fei XF,Chen H,Zhang QB,Zhao YD,Wang ZM,Wang AD,Lan Q,Huang Q

    更新日期:2012-12-01 00:00:00