Diagnostic Value of Sensitive Biomarkers for Early Kidney Damage in Diabetic Patients with Normoalbuminuria.

abstract：BACKGROUND:The decreased degradation of extra-cellular matrix proteins plays an important role in the onset of diabetic nephropathy. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1), which are members of the matrix metalloproteinase family, are associated with this process. Angiot...

journal_title：Chinese medical journal

authors： Ding HL,Guo Y,Xu MT,Li HY,Fu ZZ

更新日期：2007-11-05 00:00:00

abstract：BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...

journal_title：Chinese medical journal

authors： Sun D,Xiao JH,Bai Y,Chen MS,Hu JS,Wu GF,Mao B,Wu SH,Hu Y

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:Over 70% of the total tissue weight in the cartilage matrix consists of water, and the early-stage osteoarthritic cartilage is characterized by swelling. Water transport in the cartilage matrix and across the membranes of chondrocytes may be important in normal and pathological conditions of cartilage. The p...

journal_title：Chinese medical journal

authors： Meng JH,Ma XC,Li ZM,Wu DC

更新日期：2007-12-20 00:00:00

abstract：BACKGROUND:The mitochondrial displacement loop (D-loop) accumulates mutations and single nucleotide polymorphisms (SNPs) at a higher frequency than other regions of mitochondrial DNA (mtDNA). We previously identified disease risk-associated SNPs in the D-loop of chronic kidney disease (CKD) patients; in this study, we ...

journal_title：Chinese medical journal

authors： Bai Y,Guo Z,Xu J,Zhang J,Cui L,Zhang H,Zhang S,Ai X

更新日期：2014-01-01 00:00:00

abstract：:Of 40 patients with cervical spine tumor treated from 1980 to 1990, 24 had a primary tumor and 16 a metastatic tumor. Thirty-four patients were operated on through anterior and 5 through posterior approach. Preoperative neck pain was relieved and muscular strength of shoulder and arm increased after operation. Total e...

journal_title：Chinese medical journal

authors： Liu HK,Liu ZD

更新日期：1992-07-01 00:00:00

abstract：:An ovarian gynandroblastoma was found in a 59-year-old woman. The tumor consisting of mixed Sertoli-Leydig cells and granulosa-theca cells demonstrated no malignant features. Bisexual cells in gynandroblastoma derived from a common gonadal mesenchyme precursor or indifferent cell. The excision of appendages with tumor...

journal_title：Chinese medical journal

authors： Zhang SQ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Pioglitazone may be beneficial in the treatment of psoriasis. However, based on the effectiveness and safety considerations, it has not been widely used. To fully evaluate the strength of evidence supporting psoriasis treatment with pioglitazone, we conducted a meta-analysis of existing published studies. M...

journal_title：Chinese medical journal

authors： Zhang JZ,Ding Y,Xiang F,Yu SR,Zhang DZ,Guan MM,Kang XJ

更新日期：2020-02-20 00:00:00

abstract：OBJECTIVE:To evaluate whether hypermethylation of calcitonin (CT) gene could serve as a transforming signal of myelodysplastic syndrome (MDS) to leukemia. METHODS:Bone marrow aspirates from 35 MDS patients, including 25 refractory anemia (RA), 10 refractory anemia with excess of blasts (RAEB) or refractory anemia with...

journal_title：Chinese medical journal

authors： Wu S,Xie G,Bai R,Wang Y,Zhu P

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:It is important to choose an appropriate antiepileptic drug (AED) to manage partial epilepsy. Traditional AEDs, such as carbamazepine (CBZ) and valproate (VPA), have been proven to have good therapeutic effects. However, in recent years, a variety of new AEDs have increasingly been used as first-line treatme...

journal_title：Chinese medical journal

authors： Zhu F,Lang SY,Wang XQ,Shi XB,Ma YF,Zhang X,Chen YN,Zhang JT

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:Associations between glutamine (Gln) enriched nutrition support and surgical patients with gastrointestinal (GI) tumor remain controversy. The purpose of this meta-analysis was to assess the effect of Gln enriched nutrition support on surgical patients with GI tumor in term of relevant biochemical indices, i...

journal_title：Chinese medical journal

authors： Kang K,Shu XL,Zhang YS,Liu XL,Zhao J

更新日期：2015-01-20 00:00:00

abstract：BACKGROUND:Artificial joints present certain problems such as osteal absorption and lysis induced by wear debris which leads to loosening of the prosthesis over a period of time. Here we propose a design of an artificial magnetic suspension joint that was prepared by integrating the medical theories of modern material ...

journal_title：Chinese medical journal

authors： Dai M,Nie T

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Adenoid hypertrophy (AH) is associated with pediatric chronic rhinosinusitis (pCRS), but its role in the inflammatory process of pCRS is unclear. It is thought that innate immunity gene expression is disrupted in the epithelium of patients with chronic rhinosinusitis (CRS), including antimicrobial peptides a...

journal_title：Chinese medical journal

authors： Qu XP,Huang ZX,Sun Y,Ye T,Cui SJ,Huang Q,Ma LJ,Yang QW,Wang H,Fan EZ,Li Y,Zhang L,Zhou B

更新日期：2015-11-05 00:00:00

abstract：:The vascular pedicled periosteum was used in 11 cases in our hospital for the treatment of femoral neck fracture with good result. The follow-up period ranged from 2 to 6 years, with an average of 4 years. Animal experiment was made to elucidate the repairing process. It demonstrated that the pedicled periosteum playe...

journal_title：Chinese medical journal

authors： Zhu SX,Shen YN,Lu SB,Zhang BX,Wang JF

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Pancreatic beta-cell apoptosis induced by lipotoxicity, to a large extent, contributes to the progression of type 2 diabetes. To investigate the mechanism of free fatty acid induced apoptosis, we aimed to study the effects of palmitic acid (PA) on the apoptosis and peroxisome proliferator-activated receptor ...

journal_title：Chinese medical journal

authors： He TT,Cao XP,Chen RZ,Zhu XN,Wang XL,Li YB,Xiao HP

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility, safety and diagnostic accuracy of pharmacologic stress of (99m)Technetium-MIBI single-photon emission computed tomography (SPECT) with intravenous adenosine triphosphate (ATP) in patients with suspected coronary artery disease. METHODS:The study group included 263 patients who we...

journal_title：Chinese medical journal

authors： He Q,Yao Z,Yu X,Qu W,Sun F,Ji F,Xu F,Qian Y

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Many studies suggest that the gamma irradiation decreases allograft strength in a dose-dependent manner. However, no study has demonstrated that this decrease in strength translates into higher failure rate in meniscal allograft transplantation (MAT). The aim of this study was to investigate the effects of g...

journal_title：Chinese medical journal

authors： Zhang J,Song GY,Chen XZ,Li Y,Li X,Zhou JL

更新日期：2015-05-20 00:00:00

abstract：BACKGROUND:The Toll-like receptors (TLRs) represent a group of single-pass transmembrane receptors expressed on sentinel cells that are central to innate immune responses.The aim of this study was to investigate the presence of soluble TLRs in pleural effusions, and the diagnostic values of TLRs for pleural effusion wi...

journal_title：Chinese medical journal

authors： Yang HB,Xie KQ,Deng JM,Qin SM

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Three randomised trials have demonstrated that combining bevacizumab with first-line chemotherapy significantly improves progression-free survival versus chemotherapy alone in HER2-negative locally recurrent/metastatic breast cancer (LR/mBC). However, data from Chinese populations are limited and possible di...

journal_title：Chinese medical journal

authors： Xu BH,Jiang ZF,Shen ZZ,Guan ZZ,Chen ZD,Cheng Y,Zheng H,Jiang J,Wang XJ,Tong ZS,Qin SK,Luo Y,Yao M,Wang LW,He J

更新日期：2012-03-01 00:00:00

abstract：:The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widene...

journal_title：Chinese medical journal

authors： Dai LY,Jia LS

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Human epididymis secretory protein 4 (HE4) is a new ovarian cancer biomarker. The factors influencing HE4 levels are not clear, and the reference data in China are limited. Here, we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chi...

journal_title：Chinese medical journal

authors： Cheng HY,Zeng L,Ye X,Ma RQ,Tang ZJ,Chu HL,Zhao YM,Zhu LR,Gao YN,Chang XH,Cui H

更新日期：2020-06-05 00:00:00

abstract：OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

journal_title：Chinese medical journal

authors： Zhou Z,Li L,Yu Y,Ma Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Precise evaluation of the live donor's liver is the most important factor for the donor's safety and the recipient's prognosis in living donor liver transplantation (LDLT). Our study assessed the clinical value of computer-assisted three-dimensional quantitative assessment and a surgical planning tool for do...

journal_title：Chinese medical journal

authors： Wei L,Zhu ZJ,Lü Y,Jiang WT,Gao W,Zeng ZG,Shen ZY

更新日期：2013-04-01 00:00:00

abstract：:Dot-ELISA assay was compared with standard Sandwich ELISA in detecting parasite antigen in sera from patients with bancroftian filariasis. The same monoclonal antibody and the same serum samples were used in both assays. With Dot-ELISA, 67 of 70 serum samples from microfilaremic patients were positive at a dilution of...

journal_title：Chinese medical journal

authors： Zheng HJ,Fuhrman JA,Xu M,Cheng WF,Reddy MV,Piessens WF

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) and end-stage acute respiratory distress syndrome (ARDS) were among the most common causes of death in intensive care units. The activation of an inflammatory response and the damage of pulmonary epithelium and endotheliumwerethe hallmark of ALI/ARDS. Recent studies had demonstrated t...

journal_title：Chinese medical journal

authors： Xu YL,Liu YL,Wang Q,Li G,Lü XD,Kong B

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of U14 vaccine transfected with the B7 gene in inducing antitumor immune response to murine cervical carcinoma in Chinese 615-strain mice. METHODS:A recombinant retroviral plasmid vector expressing mouse B7-1 gene (pLNSX-mB7) was transfected into 615-strain mouse cervical carcinoma ...

journal_title：Chinese medical journal

authors： Tao G,Hu J,Zou H,Lin Q,Liu F,Wu Y,Sun Q

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Cholesterol-lowering therapy with statins has been reported to reduce the morbidity and mortality of cardiovascular diseases. This study aimed to investigate the effects of combined application of extended-release niacin and atorvastatin on lipid profile modification and the risks of adverse events in patien...

journal_title：Chinese medical journal

authors： Sang ZC,Wang F,Zhou Q,Li YH,Li YG,Wang HP,Chen SY

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Long-term use of benzalkonium chloride (BAC)-preserved drugs is often associated with ocular surface toxicity. Ocular surface symptoms had a substantial impact on the glaucoma patients' quality of life and compliance. This study aimed to investigate the effects of sodium hyaluronate (SH) on ocular surface to...

journal_title：Chinese medical journal

authors： Liu X,Yu FF,Zhong YM,Guo XX,Mao Z

更新日期：2015-09-20 00:00:00

abstract：BACKGROUND:Early detection with screening mammography can potentially reduce breast cancer mortality rates. To achieve an efficient screening, a peer review system provides a compensatory double-check reviewing, will hopefully to prevent the omission of detectable lesions and reduce unnecessary recall. METHODS:In 2009...

journal_title：Chinese medical journal

authors： Pan HB,Hsu GC,Yang TL,Huang JS,Chou CP,Liang HL,Lee SK,Chou YH,Li HJ,Wong KF

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Peripheral nerve injury causes a high rate of disability and a huge economic burden, and is currently one of the serious health problems in the world. The use of nerve grafts plays a vital role in repairing nerve defects. Acellular nerve grafts have been widely used in many experimental models as a periphera...

journal_title：Chinese medical journal

authors： Ma XL,Sun XL,Yang Z,Li XL,Ma JX,Zhang Y,Yuan ZZ

更新日期：2011-12-01 00:00:00