Peer reviewing of screening mammography in Taiwan: its reliability and the improvement.

Abstract:

BACKGROUND:Early detection with screening mammography can potentially reduce breast cancer mortality rates. To achieve an efficient screening, a peer review system provides a compensatory double-check reviewing, will hopefully to prevent the omission of detectable lesions and reduce unnecessary recall. METHODS:In 2009, 4643 initial mammographic screenings reported by 74 screening radiologists had negative results with a recall rate of less than 5%. In the same year, 2538 initial positives screened by 18 screening radiologists had a recall rate higher than 15%. Those 7181 randomized screenings were evenly distributed for reassessment by 39 reviewing radiologists. The disagreement of assessments between the reviewers and screening radiologists was recorded. The differential rate was defined as the number of the disagreements divided by the number of audited films reviewed by a screening radiologist. The equality of the differential rates for each screening radiologists with negative and positive assessments was compared by a Chi-square test. The performance of the 39 auditors was measured by the Kendall's tau statistic. P values less than 0.05 were considered statistically significant. RESULTS:The mean differential rate for screening radiologists of negative assessments was 6.7% (P = 0.588), while 35.0% for positive assessments were significant (P < 0.001). The result indicated that most of the initial negative assessments reported by the screening radiologists were generally accepted by the reviewers but not the positive assessments. With respect to the 39 reviewers, there was no significant evidence for the association of the difference rates between negative and positive assessments. Nine reviewers were found to have their differential rate for negative and positive assessments larger than the average of the population. Eleven reviewers were found to have their differential rates smaller than the average for both. Thirteen reviewers had their differential rates smaller than the average for negative assessments but larger than the average for positive assessments. The opposite condition was found for six reviewers. The Kendall's tau statistic was 0.038 (P = 0.735). CONCLUSIONS:Reviewers usually agreed with the opinion of the initial screening doctors who reported negative findings. Therefore, a 5% recall rate as the lower range of reviewing negatives may be still too high. The recall rate of more than 15% was significantly related to improper interpretation, especially when the differential rate is 25% or higher, a warning to the underperforming screening radiologist is recommended. An ideal reviewer should interpret films independently. Reviewers with tendencies to be followers or contrarians should not be enrolled in the reviewing system.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Pan HB,Hsu GC,Yang TL,Huang JS,Chou CP,Liang HL,Lee SK,Chou YH,Li HJ,Wong KF

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

68-71

issue

1

eissn

0366-6999

issn

2542-5641

journal_volume

126

pub_type

杂志文章
  • Aldosterone biosynthesis in extraadrenal tissues.

    abstract:OBJECTIVE:To determine whether extraadrenal tissues synthesize aldosterone in addition to vascular tissue and brain. METHODS:Ex vivo kidney perfusion was performed in normal Wistar rats, ACEI pretreated and adrenalectomized rats prior to the perfusion experiment. After equilibration for 30 minutes, 120 ml of perfusate...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wu P,Liang X,Dai Y,Liu H,Zang Y,Guo Z,Zhang R,Lai W,Zhang Y,Liu Y

    更新日期:1999-05-01 00:00:00

  • In vitro study of safety and co-efficiency of the transbronchial coagulation techniques.

    abstract:BACKGROUND:The usual transbronchial coagulation techniques include microwave, argon plasma coagulation (APC), electrocautery and cryotherapy. However, there are serious clinical problems in the safety of each. By analyzing the experimental data and clinical observations, we observed the variable effects of different co...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Bai C,Dong YC,Song XL,Huang Y,Shi H,Hu ZL,Li Q

    更新日期:2013-01-01 00:00:00

  • Early activation of caspase-1 after retinal ischemia and reperfusion injury in mice.

    abstract:BACKGROUND:Caspases are important in the signaling pathway of cellular apoptosis. Caspase-3 protein expression has been shown to increase and parallel to neuronal apoptosis in retinal ischemia injury. This study was to determine whether caspase-1 is involved in neuronal cell death or in retinal ischemia and reperfusion...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zheng GY,Zhang C,Li ZG

    更新日期:2004-05-01 00:00:00

  • Mutation analysis of potassium channel genes KCNQ1 and KCNH2 in patients with long QT syndrome.

    abstract:OBJECTIVE:To determine mutations of two common potassium channel subunit genes KCNQ1, KCNH2 causing long QT syndrome (LQTS) in the Chinese. METHODS:Thirty-one Chinese LQTS pedigrees were characterized for mutations in the two LQTS genes, KCNQ1 and KCNH2, by sequencing. RESULTS:Two novel KCNQ1 mutations, S277L in the ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu W,Hu D,Li C,Li P,Li Y,Li Z,Li L,Qin X,Dong W,Qi Y,Chen S,Wang Q

    更新日期:2003-09-01 00:00:00

  • Quantitative evaluation of acute renal failure in rabbits with contrast-enhanced ultrasound.

    abstract:BACKGROUND:Assessment of perfusion in the early period of acute renal failure (ARF) is important, and can not be made by conventional ultrasound. The aim of this study was to prospectively test in a rabbit ARF model whether real-time contrast-enhanced ultrasound (CEUS) can quantitatively evaluate the hemodynamic change...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Dong Y,Wang WP,Cao JY,Fan PL,Lin XY

    更新日期:2012-02-01 00:00:00

  • RANTES In1.1C allele polymorphisms in 13 Chinese ethnic populations.

    abstract:BACKGROUND:The In1.1C single nucleotide polymorphism (SNP) allele results in reduced RANTES transcription, which is associated with increased frequency of HIV-1 infection, and rapid progression to AIDS among HIV-1-infected individuals. This study aimed to study the mutant frequency and polymorphism of RANTES in Chinese...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Qian Y,Sun H,Chu JY

    更新日期:2009-05-20 00:00:00

  • In vivo Confocal Microscopy Evaluation of Meibomian Gland Dysfunction in Dry Eye Patients with Different Symptoms.

    abstract:BACKGROUND:Dry eye patients suffer from all kinds of symptoms. Sometimes, the clinical signs evaluation does not disclose any obvious difference in routine examination; in vivo confocal microscopy (IVCM) is a powerful tool for ocular surface disease. This study aimed to clarify meibomian gland (MG) alterations in dry e...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.192782

    authors: Zhao H,Chen JY,Wang YQ,Lin ZR,Wang S

    更新日期:2016-11-05 00:00:00

  • Down-regulation of peroxisome proliferator-activated receptor γ coactivator-1α expression in fatty acid-induced pancreatic beta-cell apoptosis involves nuclear factor-κB pathway.

    abstract:BACKGROUND:Pancreatic beta-cell apoptosis induced by lipotoxicity, to a large extent, contributes to the progression of type 2 diabetes. To investigate the mechanism of free fatty acid induced apoptosis, we aimed to study the effects of palmitic acid (PA) on the apoptosis and peroxisome proliferator-activated receptor ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: He TT,Cao XP,Chen RZ,Zhu XN,Wang XL,Li YB,Xiao HP

    更新日期:2011-11-01 00:00:00

  • Pathological demography of native patients in a nephrology center in China.

    abstract:OBJECTIVE:To analysis the pathological demography in Chinese patients undergoing renal biopsy from our nephrology center. METHODS:Between January 1979 and October 2000 in Jinling Hospital, Nanjing, China, 10,002 attempts of percutaneous renal were performed in patients with renal disease from 33 provinces of China. Th...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen H,Tang Z,Zeng C,Hu W,Wang Q,Yu Y,Yao X,Wang J,Zhu M,Zhou H,Liu H,Liu Z,Li L

    更新日期:2003-09-01 00:00:00

  • Value of polymerase chain reaction assay in diagnosis of intestinal tuberculosis and differentiation from Crohn's disease.

    abstract::It is difficult to make a precise diagnosis of intestinal tuberculosis and to differentiate it from Crohn's disease. For evaluating Polymerase Chain Reaction (PCR) assay in these two aspects, 36 specimens of intestinal tuberculosis from surgical resections and endoscopic biopsies and 26 Crohn's disease samples were su...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Gan H,Ouyang Q,Bu H,Li S,Chen D,Li G,Yang X

    更新日期:1995-03-01 00:00:00

  • Interrelation between nitric oxide and endothelin-1 in an experimental acute hypoxia in rats and its intervention.

    abstract:OBJECTIVES:To study the interrelation between nitric oxide (NO) and endothelin-1 (ET1) in experimental acute hypoxic rats, and to evaluate the mechanism of acute hypoxic pulmonary hypertension affected by NO and ET1 and its intervention. METHODS:Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemi...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang Y,Zhang L,Shen W,Chen L,Fan S

    更新日期:1999-04-01 00:00:00

  • Expression of Innate Immunity Genes in Epithelial Cells of Hypertrophic Adenoids with and without Pediatric Chronic Rhinosinusitis: A Preliminary Report.

    abstract:BACKGROUND:Adenoid hypertrophy (AH) is associated with pediatric chronic rhinosinusitis (pCRS), but its role in the inflammatory process of pCRS is unclear. It is thought that innate immunity gene expression is disrupted in the epithelium of patients with chronic rhinosinusitis (CRS), including antimicrobial peptides a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.168056

    authors: Qu XP,Huang ZX,Sun Y,Ye T,Cui SJ,Huang Q,Ma LJ,Yang QW,Wang H,Fan EZ,Li Y,Zhang L,Zhou B

    更新日期:2015-11-05 00:00:00

  • Endolymphatic sac papillary tumor: a case report.

    abstract::Endolymphatic sac papillary tumor (ELST) is an extremely rare and aggressive tumor characterized by hearing loss and temporal bone destruction. A case with clinical, imaging, pathologic and treatment data is reported and relevant literature is reviewed. A 25-year-old woman, with ELST underwent craniotomy for tumor sub...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Yu SJ,Chen YD,Gao F,Qiu XG,Chang H

    更新日期:2011-11-01 00:00:00

  • Iron chelator daphnetin against Pneumocystis carinii in vitro.

    abstract:BACKGROUND:Although there are several drugs and drug combinations for the treatment of Pneumocystis carinii (P. carinii) pneumonia, all drugs have the toxicity as well as low efficacy. Iron chelators have been proposed as a source of new drugs for combating these infections. We hypothesized that iron chelators would su...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ye B,Zheng YQ,Wu WH,Zhang J

    更新日期:2004-11-01 00:00:00

  • Evaluation of glucose metabolic disorder: insulin resistance and insulin receptors in critically ill children.

    abstract:OBJECTIVE:To explore the pathogenesis of glucose metabolic disorder and insulin resistance in critically ill children under severe stress. METHODS:To test glucose, lactate, glucagon, insulin, c-peptide, cortisol levels in 50 critically ill children. While we measured 125I-insulin binding to erythrocytes of 13 critical...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xu F,Yang X,Lu Z,Kuang F

    更新日期:1996-10-01 00:00:00

  • Resection of a giant renal angiomyolipoma in a solitary kidney with preoperative arterial embolization.

    abstract::Renal angiomyolipoma is a type of benign tumor that occurs sporadically in addition to being associated with tuberous sclerosis. Preoperative embolization of large tumors is important to avoid excessive blood loss during surgery. We reported a patient with a 5505-g giant renal angiomyolipoma in a solitary kidney. The ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Shen WH,Pan JH,Yan JN,Chen ZW,Zhou ZS,Lu GS,Li WB

    更新日期:2011-05-01 00:00:00

  • Angiographic prevalence of myocardial bridging in a defined very large number of Chinese patients with chest pain.

    abstract:BACKGROUND:Muscle fibers overlying the intramyocardial segment of an epicardial coronary artery are termed myocardial bridging (MB). Variable prevalence of MB has been described at autopsy and angiographic series with small and large sample size studies. In addition, no similar study was reported in Chinese population....

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li JJ,Shang ZL,Yao M,Li J,Yang YJ,Chen JL,Qiao SB,Ma WH,Qin XW,Liu HB,Wu YJ,Yuan JQ,Chen J,You SJ,Dai J,Xu B,Xia R,Gao RL

    更新日期:2008-03-05 00:00:00

  • Relationship between Modulator Recognition Factor 2/AT-rich Interaction Domain 5B Gene Variations and Type 2 Diabetes Mellitus or Lipid Metabolism in a Northern Chinese Population.

    abstract:BACKGROUND:Four single nucleotide polymorphisms (SNPs) in the modulator recognition factor 2/AT-rich interaction domain 5B (MRF2/ARID5B) gene located at chromosome 10q21.2 have been shown to be associated with both type 2 diabetes mellitus (T2DM) and coronary artery disease in a Japanese cohort. This study aimed to inv...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.204926

    authors: Sun LL,Zhang SJ,Chen MJ,Elena K,Qiao H

    更新日期:2017-05-05 00:00:00

  • Synchronous intraoperative radiofrequency ablation for multiple liver metastasis and resection of giant solid pseudopapillary tumors of the pancreas.

    abstract::The solid pseudopapillary tumors of the pancreas (SPTP) are rare tumors, which are commonly found in adolescent women. Radical surgical resection of the primary tumor or metastases is the standard treatment for SPTP and could achieve long-term survival. We reported a case of a 20-year-old female with multiple liver me...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li JX,Wu H,Huang JW,Prasoon P,Zeng Y

    更新日期:2012-05-01 00:00:00

  • Effect of homocysteine on plaque formation and oxidative stress in patients with acute coronary syndromes.

    abstract:BACKGROUND:Cardiovascular diseases, especially coronary artery disease (CAD), are major causes of death in industrialized countries. Elevated concentrations of plasma homocysteine (Hcy) have been associated with an increased risk of CAD. Increased plasma levels of chemokine, characterized by their ability to induce mig...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang G,Mao JM,Wang X,Zhang FC

    更新日期:2004-11-01 00:00:00

  • Comparison of visual performance between conventional LASIK and wavefront-guided LASIK with iris-registration.

    abstract:BACKGROUND:Laser in situ keratomileusis (LASIK) has become an efficient and commonly performed procedure to reduce refractive errors. In order to further increase the postoperative visual quality, the wavefront-guided refractive surgery has been a research hotspot in customized surgery. This study was conducted to comp...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang J,Zhou YH,Wang NL,Li R

    更新日期:2008-01-20 00:00:00

  • Supplementary inferior phrenic artery embolization in the interventional treatment of hemoptysis.

    abstract:BACKGROUND:Transcatheter bronchial artery embolization (BAE) is widely used for the treatment of hemoptysis and the immediate success rate is high, but there are still some hemorrhage recurrences. One of the common reasons for failure of BAE is collateral branches as blood supply. The inferior phrenic artery (IPA) is o...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu FY,Wang MQ,Fan QS,Duan F,Wang ZJ,Song P

    更新日期:2009-03-05 00:00:00

  • Presence of serum antinuclear antibodies correlating unfavorable overall survival in patients with chronic lymphocytic leukemia.

    abstract:BACKGROUND:Serum antinuclear antibodies (ANAs) are positive in some patients with chronic lymphocytic leukemia (CLL), but the prognostic value of ANAs remains unknown. The aim of this study was to evaluate the role of ANAs as a prognostic factor in CLL. METHODS:This study retrospectively analyzed clinical data from 21...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000114

    authors: Sun Q,Wang L,Zhu HY,Miao Y,Wu W,Liang JH,Cao L,Xia Y,Wu JZ,Wang Y,Wang R,Fan L,Xu W,Li JY

    更新日期:2019-03-05 00:00:00

  • The relationship between tumor necrosis factor-alpha gene polymorphisms and acute severe pancreatitis.

    abstract:OBJECTIVE:To investigate the relationship between the presence of the TNF2 allele and plasma concentrations of tumor necrosis factor-alpha (TNF alpha) and soluble TNF receptor (sTNF-R) with the development of acute severe pancreatitis (ASP) and severe sepsis. METHODS:Genomic DNA was prepared from peripheral blood leuk...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang D,Li J,Jiang Z,Yu B,Tang X,Li W

    更新日期:2003-11-01 00:00:00

  • Effect of antimicrobial agents on the toll-like receptors and inflammatory cytokines in liver tissue of the alcohol-induced liver disease in rats with Vibrio vulnificus sepsis.

    abstract:BACKGROUND:Septicemia and inflammation-mediated septic shock caused by Vibrio vulnificus (VV) is strongly associated with chronic liver disease. This study examined the effects of antimicrobial therapy on expression of hepatic toll-like receptors and inflammatory cytokines in rats with alcohol-induced liver disease com...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Lu ZQ,Li MF,Qiu QM,Liang H,Zhou TL,Hong GL,Wu B

    更新日期:2009-08-20 00:00:00

  • Serological survey of nasopharyngeal carcinoma in 21 cities of south China.

    abstract::This paper reports the results of serological survey of 318,912 persons for nasopharyngeal carcinoma (NPC) in 21 cities and counties of south China. There were 8,441 persons with positive VCA-IgA antibody (single item positive) of EB virus (EBV), with a rate of 2.65%. In these VCA-IgA positive persons, 287 persons als...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Deng H,Zeng Y,Lei Y,Zhao Z,Wang P,Li B,Pi Z,Tan B,Zheng Y,Pan W

    更新日期:1995-04-01 00:00:00

  • Efficacy of catheter ablation of atrial fibrillation beyond HATCH score.

    abstract:BACKGROUND:HATCH score is an established predictor of progression from paroxysmal to persistent atrial fibrillation (AF). The purpose of this study was to determine if HATCH score could predict recurrence after catheter ablation of AF. METHODS:The data of 488 consecutive paroxysmal AF patients who underwent an index c...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Tang RB,Dong JZ,Long DY,Yu RH,Ning M,Jiang CX,Sang CH,Liu XH,Ma CS

    更新日期:2012-10-01 00:00:00

  • Prognostic impact of splenectomy on advanced proximal gastric cancer with No. 10 lymph node metastasis.

    abstract:BACKGROUND:This study evaluated the prognostic impact of D2 lymphadenectomy combined with splenectomy in patients with advanced proximal gastric cancer and lymph node metastasis at the splenic hilum (No. 10 lymph nodes). METHODS:The clinical records of 216 patients with advanced proximal gastric cancer and No. 10 lymp...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Huang CM,Wang JB,Lu HS,Zheng CH,Li P,Xie JW,Zhang XF

    更新日期:2009-11-20 00:00:00

  • Expression of TGF-beta 1, PDGF and IGF-1 mRNA in lung of bleomycin-A5-induced pulmonary fibrosis in rats.

    abstract:OBJECTIVE:To investigate the influence of alveolar macrophages (AMs), fibroblasts and interstitial cells on development of lung fibrosis, and the interactions among TGF-beta 1 PDGF and IGF-1 and these cytokines-effects on lung fibrosis. MATERIAL AND METHODS:Expressions of TGF-beta 1, PDGF and IGF-1 mRNA in the lung ce...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li H,He B,Que C,Weng B

    更新日期:1996-07-01 00:00:00

  • Effect of repaglinide and gliclazide on glycaemic control, early-phase insulin secretion and lipid profiles in.

    abstract:BACKGROUND:Both repaglinide and gliclazide are insulin secretagogues widely used in the treatment of type 2 diabetes. They stimulate insulin secretion through distinct mechanisms and may benefit patients from different aspects. The present study was to evaluate the effects of repaglinide or gliclazide on glycaemic cont...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Zhang H,Bu P,Xie YH,Luo J,Lei MX,Mo ZH,Liao EY

    更新日期:2011-01-01 00:00:00