Comparison of visual performance between conventional LASIK and wavefront-guided LASIK with iris-registration.

Abstract:

BACKGROUND:Laser in situ keratomileusis (LASIK) has become an efficient and commonly performed procedure to reduce refractive errors. In order to further increase the postoperative visual quality, the wavefront-guided refractive surgery has been a research hotspot in customized surgery. This study was conducted to compare the visual acuity, higher-order aberration, and contrast sensitivity of wavefront-guided LASIK with iris-registration and conventional LASIK. METHODS:Two hundred and eleven myopic eyes of 109 patients were enrolled in this prospective study and randomly divided into two groups: the wavefront-guided LASIK (wg LASIK) group (94 eyes) and conventional LASIK group (117 eyes). A Wavescan Wavefront aberrometer was used to analyze Zernike coefficients and the root-mean-square (RMS) of higher order aberrations with 6.0 mm pupil size, and Optec 6500 visual function instrument was used to measure contrast sensitivity (CS) under 5 spatial frequencies before and after surgery in both groups. RESULTS:The uncorrected visual acuity (UCVA) and the mean spherical equivalent (SE) in wg LASIK group were significantly better than those in conventional LASIK (UCVA, z = 2.339, P = 0.019; SE, t = 2.838, P = 0.005) at 3 months after surgery. Moreover, the increase in Z(3)(-3), Z(3)(1), Z(3)(3), Z(4)(0), Z(5)(-1), Z(5)(1), Z(5)(5) and Z(6)(-6) in wg LASIK group was statistically smaller than that in conventional LASIK group (P < 0.05). In wg LASIK group, eyes with a higher amount of the preoperative RMS of the higher order aberrations (RMSh = 0.30 microm) showed a statistically lower increase (13.5%) than those in conventional LASIK group at 3 months after surgery (33.3%) (P = 0.004). And the values of 4th order spherical aberration (4thSA) and the root mean square of 6th order aberration (RMS6) in wg LASIK group were significantly lower than those in conventional group in eyes which had higher preoperative astigmatism (= 1.0D) (4thSA, P = 0.03; RMS6, P = 0.02). Wg LASIK group showed better CS values than the correspondingly preoperative values at all spatial frequencies with and without glare at 3 months after the surgery while conventional LASIK group displayed reduced CS values except for 1.5 and 3 cycles per degree with glare. The differences between the two groups were statistically significant (P < 0.001). CONCLUSIONS:Wavefront-guided LASIK with iris-registration is efficient to reduce higher order aberrations especially spherical and coma aberrations, and to improve postoperative visual acuity and contrast sensitivity compared with conventional LASIK. The application of wavefront-guided LASIK with iris-registration is particularly suitable for eyes with higher preoperative RMSh values and eyes with higher preoperative astigmatism.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Zhang J,Zhou YH,Wang NL,Li R

subject

Has Abstract

pub_date

2008-01-20 00:00:00

pages

137-42

issue

2

eissn

0366-6999

issn

2542-5641

journal_volume

121

pub_type

杂志文章
  • Endovenous laser ablation of great saphenous vein with ultrasound-guided perivenous tumescence: early and midterm results.

    abstract:BACKGROUND:Endovenous laser ablation (EVLA) is an improved method to treat varicose great saphenous veins (GSV) with a high satisfactory rate. This study aimed to evaluate the efficiency and safety of treatment by EVLA procedures with ultrasound-guided perivenous tumescence. METHODS:Thirty-one patients (31 limbs) with...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen JQ,Xie H,Deng HY,Yuan K,Zhang JW,Zhang H,Zhang L

    更新日期:2013-02-01 00:00:00

  • Surgical outcome and clinical follow-up in patients with symptomatic myocardial bridging.

    abstract:BACKGROUND:Myocardial bridging with systolic compression of the left anterior descending coronary artery (LAD) may be associated with myocardial ischaemia. The clinical outcome in patients with surgical treatment for symptomatic myocardial bridging remains undetermined. This study assessed the middle- and long-term res...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Huang XH,Wang SY,Xu JP,Song YH,Sun HS,Tang Y,Dong C,Yang YJ,Hu SS

    更新日期:2007-09-20 00:00:00

  • Curcumin improves learning and memory ability and its neuroprotective mechanism in mice.

    abstract:BACKGROUND:Increasing evidence suggests that many neurons may die through apoptosis in Alzheimer's disease (AD). Mitochondrial dysfunction has been implicated in this process of neuronal cell death. One promising approach for preventing AD is based upon anti-apoptosis to decrease death of nerve cells. In this study, we...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Pan R,Qiu S,Lu DX,Dong J

    更新日期:2008-05-05 00:00:00

  • Functional recovery after rhesus monkey spinal cord injury by transplantation of bone marrow mesenchymal-stem cell-derived neurons.

    abstract:BACKGROUND:The treatment of spinal cord injury is still a challenge. This study aimed at evaluating the therapeutical effectiveness of neurons derived form mesenchymal stem cells (MSCs) for spinal cord injury. METHODS:In this study, rhesus MSCs were isolated and induced by cryptotanshinone in vitro and then a process ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Deng YB,Yuan QT,Liu XG,Liu XL,Liu Y,Liu ZG,Zhang C

    更新日期:2005-09-20 00:00:00

  • The status of drug resistance and ampC gene expression in Enterobacter cloacae.

    abstract:OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou Z,Li L,Yu Y,Ma Y

    更新日期:2003-08-01 00:00:00

  • Fatigue cyclic loading test of an auro-galvanoforming ceramic bridge.

    abstract:BACKGROUND:In dental clinics, dentition defects are commonly restored with conventional porcelain-fused-to-metal fixed bridges. However, Ni-Cr alloy ceramic fixed bridges are known to have several drawbacks such as marginal coloration of the neck, low casting precision and, most seriously, poor biocompatibility. These ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang XH,Sun F,Wang H,Xu MQ

    更新日期:2008-10-05 00:00:00

  • CSF-VP shunt placement and albendazole therapy for cerebral cysticercosis.

    abstract::Cerebral cysticercosis is the most common worldwide parasitic infection of the central nervous system. Intraventricular involvement is apparent in 15% to 28.8% of cases with neural compartment infestation.' Although different forms of the disease (parenchymatous, subarachnoid, and mixed form ) have been treated succes...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhu L,Weng X,Shi Y,Pan X,Mo L

    更新日期:2002-06-01 00:00:00

  • Pediatric Hemorrhagic Stroke Complicates Interventions for Congenital Heart Disease: Experiences from Two Centers.

    abstract:: ...

    journal_title:Chinese medical journal

    pub_type: 信件

    doi:10.4103/0366-6999.246070

    authors: Xi SB,Xie YM,Li T,Li YF,Qian MY,Zhang ZW

    更新日期:2018-12-05 00:00:00

  • Evidence of compromised circulation in the pathogenesis of optic nerve damage in chronic glaucomatous rabbit.

    abstract::The protective effect of improving the microcirculation on the retinal ganglion cells (RGC) and the ultrastructure of the optic nerve after intravenous (i.v.) use of Salviae miltiorrhiza (SMR) was studied in a chronic intraocular hypertension model in 36 rabbits. These rabbits were treated with topical 0.5% timolol, o...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhu MD,Cai FY

    更新日期:1993-12-01 00:00:00

  • A frozen-thawed embryo transfer program improves the embryo utilization rate.

    abstract:BACKGROUND:Frozen-thawed embryo transfer (FET) is the most common way to prevent serious late ovarian hyperstimulation syndrome and increase the cumulative pregnancy rate. We evaluated the effectiveness of an FET program for improving the embryo implantation and clinical pregnancy rates, and ultimate embryo utilization...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhou F,Lin XN,Tong XM,Li C,Liu L,Jin XY,Zhu HY,Zhang SY

    更新日期:2009-09-05 00:00:00

  • Oxaliplatin-based combination chemotherapy is still effective for the treatment of recurrent and platinum-resistant epithelial ovarian cancer: results from a single center.

    abstract:BACKGROUND:Combination paclitaxel and carboplatin is currently a first-line regimen for ovarian cancer. However, many patients develop tumor recurrence or drug resistance to this regimen. The study aims to investigate the effectiveness and safety of an oxaliplatin + epirubicin + ifosfamide regimen for the treatment of ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhang G,Li XP,Liu BJ,Wang JL,Wang SJ,Cui H,Wei LH

    更新日期:2013-12-01 00:00:00

  • Presence of serum antinuclear antibodies correlating unfavorable overall survival in patients with chronic lymphocytic leukemia.

    abstract:BACKGROUND:Serum antinuclear antibodies (ANAs) are positive in some patients with chronic lymphocytic leukemia (CLL), but the prognostic value of ANAs remains unknown. The aim of this study was to evaluate the role of ANAs as a prognostic factor in CLL. METHODS:This study retrospectively analyzed clinical data from 21...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000114

    authors: Sun Q,Wang L,Zhu HY,Miao Y,Wu W,Liang JH,Cao L,Xia Y,Wu JZ,Wang Y,Wang R,Fan L,Xu W,Li JY

    更新日期:2019-03-05 00:00:00

  • Aldosterone biosynthesis in extraadrenal tissues.

    abstract:OBJECTIVE:To determine whether extraadrenal tissues synthesize aldosterone in addition to vascular tissue and brain. METHODS:Ex vivo kidney perfusion was performed in normal Wistar rats, ACEI pretreated and adrenalectomized rats prior to the perfusion experiment. After equilibration for 30 minutes, 120 ml of perfusate...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wu P,Liang X,Dai Y,Liu H,Zang Y,Guo Z,Zhang R,Lai W,Zhang Y,Liu Y

    更新日期:1999-05-01 00:00:00

  • A bicistronic retroviral vector to introduce drug resistance genes into human umbilical cord blood CD34+ cells to improve combination chemotherapy tolerance.

    abstract:OBJECTIVE:To study whether human umbilical cord blood CD34+ cells transduced with human aldehyde dehydrogenase class-1 (ALDH-1) and multidrug resistance gene (MDR1) have increases resistance to 4-Hydroperoxycyclo-phosphamide (4-HC) and P-glycoprotein effluxed drugs. METHODS:A bicistronic retroviral vector G1Na-ALDH1-I...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang J,Chen Z,Xia X,Lu D,Xue J,Ruan C

    更新日期:2001-01-01 00:00:00

  • Medial support nail and proximal femoral nail antirotation in the treatment of reverse obliquity inter-trochanteric fractures (Arbeitsgemeinschaft fur Osteosynthesfrogen/Orthopedic Trauma Association 31-A3.1): a finite-element analysis.

    abstract:BACKGROUND:The reverse obliquity inter-trochanteric fracture is a distinct fracture pattern that is mechanically different from most inter-trochanteric fractures and the optional treatment of it is still controversial. The purpose of this study was to compare differences in the efficacy of a novel nail (medial support ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000001031

    authors: Nie SB,Zhao YP,Li JT,Zhao Z,Zhang Z,Zhang LC,Tang PF

    更新日期:2020-11-20 00:00:00

  • Impact of multidisciplinary team working on the management of colorectal cancer.

    abstract:BACKGROUND:The continual and rapid development of techniques which are used for diagnosis and treatment makes management of colorectal cancer more difficult depending on single discipline. Colorectal cancer multidisciplinary team (MDT) working model is recommended by UK and other countries, but there is little informat...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ye YJ,Shen ZL,Sun XT,Wang ZF,Shen DH,Liu HJ,Zhang WL,Chen YL,Zhou J,Poston GJ,Wang S

    更新日期:2012-01-01 00:00:00

  • Endocrine therapy combined with targeted therapy in hormone receptor-positive metastatic breast cancer.

    abstract::Increasing numbers of targeted drugs are used in hormone receptor (HR)-positive metastatic breast cancer (MBC) to overcome or delay resistance to endocrine therapy. This study will systemically review the progress made in endocrine therapy combined with targeted therapy in the treatment of HR-positive MBC. From the "A...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000923

    authors: Bian L,Xu FR,Jiang ZF

    更新日期:2020-10-05 00:00:00

  • Biomechanical properties of peripheral nerve after acellular treatment.

    abstract:BACKGROUND:Peripheral nerve injury causes a high rate of disability and a huge economic burden, and is currently one of the serious health problems in the world. The use of nerve grafts plays a vital role in repairing nerve defects. Acellular nerve grafts have been widely used in many experimental models as a periphera...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ma XL,Sun XL,Yang Z,Li XL,Ma JX,Zhang Y,Yuan ZZ

    更新日期:2011-12-01 00:00:00

  • Neuroprotective effect of exogenous vascular endothelial growth factor on rat spinal cord neurons in vitro hypoxia.

    abstract:BACKGROUND:Vascular endothelial growth factor (VEGF) is well known as a hypoxia-induced protein. That it markedly increased expression of VEGF and improvement of rat motor function after spinal cord injury suggested that VEGF could play a neuroprotective role in ischaemic tolerance. This study investigated whether vasc...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ding XM,Mao BY,Jiang S,Li SF,Deng YL

    更新日期:2005-10-05 00:00:00

  • Incubation and application of transgenic green fluorescent nude mice in visualization studies on glioma tissue remodeling.

    abstract:BACKGROUND:The primary reasons for local recurrence and therapeutic failure in the treatment of malignant gliomas are the invasion and interactions of tumor cells with surrounding normal brain cells. However, these tumor cells are hard to be visualized directly in histopathological preparations, or in experimental glio...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Dong J,Dai XL,Lu ZH,Fei XF,Chen H,Zhang QB,Zhao YD,Wang ZM,Wang AD,Lan Q,Huang Q

    更新日期:2012-12-01 00:00:00

  • Clinical study on the thrombolytic effect with different doses of urokinase in acute myocardial infarction. The Collaborative Research Group on Thrombolysis.

    abstract:OBJECTIVE:To investigate the effects of different doses of intravenous domestic urokinase. METHODS:One thousand and twenty three cases of acute myocardial infarction within 6 hours after acute onset were divided randomly into two groups with 539 cases in the low dose group (urokinase 22,000IU/kg, total dose not lower ...

    journal_title:Chinese medical journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors:

    更新日期:1997-01-01 00:00:00

  • Na (+) /Ca (2+) Exchanger 3 is Downregulated in the Hippocampus and Cerebrocortex of Rats with Hyperthermia-induced Convulsion.

    abstract:BACKGROUND:Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induc...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.169103

    authors: Sun D,Xiao JH,Bai Y,Chen MS,Hu JS,Wu GF,Mao B,Wu SH,Hu Y

    更新日期:2015-11-20 00:00:00

  • Effect of a cyclosporine A delivery system in corneal transplantation.

    abstract:OBJECTIVE:To test the immunosuppressive effect of cyclosporine (Cs) in a polymer placed in the anterior chamber of corneal allograft recipients. METHODS:Wistar inbred rats with vascularized corneas were recipients of corneal allografts from Sprague-Dawley donor rats. Rats underwent penetrating keratoplasty and were di...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xie L,Shi W,Wang Z,Bei J,Wang S

    更新日期:2002-01-01 00:00:00

  • Perioperative factors related to prognosis of regular hepatectomy in comparison with irregular hepatectomy.

    abstract:BACKGROUND:The aim of this research was to analyze the perioperative factors of regular hepatectomy and irregular hepatectomy. The superiority of the clinical application of the two methods was compared in the perioperative period. METHODS:From 1986 to 2011, 1798 patients underwent consecutive liver resections with re...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Feng Z,Li H,Zhang J,Xu L,Xiao M,Huang Z,Zhang H

    更新日期:2014-01-01 00:00:00

  • Prognostic analysis of orthostatic intolerance using survival model in children.

    abstract:BACKGROUND:Orthostatic intolerance (OI) is a common disease at pediatric period which has a serious impact on physical and mental health of children. The purpose of this study was to investigate the effect of related factors on the prognosis of children with OI. METHODS:The subjects were 170 children with OI, includin...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li Y,Li H,Li X,Li X,Jin H

    更新日期:2014-01-01 00:00:00

  • Relationship between Modulator Recognition Factor 2/AT-rich Interaction Domain 5B Gene Variations and Type 2 Diabetes Mellitus or Lipid Metabolism in a Northern Chinese Population.

    abstract:BACKGROUND:Four single nucleotide polymorphisms (SNPs) in the modulator recognition factor 2/AT-rich interaction domain 5B (MRF2/ARID5B) gene located at chromosome 10q21.2 have been shown to be associated with both type 2 diabetes mellitus (T2DM) and coronary artery disease in a Japanese cohort. This study aimed to inv...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.204926

    authors: Sun LL,Zhang SJ,Chen MJ,Elena K,Qiao H

    更新日期:2017-05-05 00:00:00

  • Lectin histochemistry in psoriasis, lichen planus and seborrheic keratosis.

    abstract::Lectin binding patterns in psoriasis, lichen planus and seborrheic keratosis lesions were studied using 14 different biotinyl lectins and avidin-horseradish peroxidase. Compared with normal epidermis, there were significant quantitative and qualitative differences, some of which were characteristic. ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Gao MY,Lin XR,Miao Q

    更新日期:1992-12-01 00:00:00

  • Cordocentesis: a useful method for prenatal diagnosis.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of cordocentesis for prenatal diagnosis of various fetal diseases. PATIENTS AND METHODS:Fetal blood sampling was performed in 30 pregnancies from gestational week 19 to 36 for various prenatal diagnoses. We used Aloka SSD-650 real-time ultrasound scanner with 3.5 mHz curvi...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xiang Y,Sun N,Chang X,Bian X,Wang F

    更新日期:1996-04-01 00:00:00

  • Interrelation between nitric oxide and endothelin-1 in an experimental acute hypoxia in rats and its intervention.

    abstract:OBJECTIVES:To study the interrelation between nitric oxide (NO) and endothelin-1 (ET1) in experimental acute hypoxic rats, and to evaluate the mechanism of acute hypoxic pulmonary hypertension affected by NO and ET1 and its intervention. METHODS:Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemi...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang Y,Zhang L,Shen W,Chen L,Fan S

    更新日期:1999-04-01 00:00:00

  • Peer reviewing of screening mammography in Taiwan: its reliability and the improvement.

    abstract:BACKGROUND:Early detection with screening mammography can potentially reduce breast cancer mortality rates. To achieve an efficient screening, a peer review system provides a compensatory double-check reviewing, will hopefully to prevent the omission of detectable lesions and reduce unnecessary recall. METHODS:In 2009...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Pan HB,Hsu GC,Yang TL,Huang JS,Chou CP,Liang HL,Lee SK,Chou YH,Li HJ,Wong KF

    更新日期:2013-01-01 00:00:00