Evidence of compromised circulation in the pathogenesis of optic nerve damage in chronic glaucomatous rabbit.

abstract：OBJECTIVE:To explore the response of nasal mucosa epithelial cells to hypoxia in terms of formation of nasal polyps (NP). METHODS:Epithelial cells of NP and inferior turbinate (IT) were cultured serum-free under normal oxygen and hypoxic circumstances with stimulation of IL-1 beta and TNF alpha. The vascular endotheli...

journal_title：Chinese medical journal

authors： Jiang S,Dong Z,Zhu D,Yang Z

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Green tea has been shown to improve cholesterol metabolism in animal studies, but the molecular mechanisms underlying this function have not been fully understood. Long non-coding RNAs (lncRNAs) have recently emerged as a major class of regulatory molecules involved in a broad range of biological processes a...

journal_title：Chinese medical journal

authors： Liu G,Zheng X,Xu Y,Lu J,Chen J,Huang X

更新日期：2015-01-05 00:00:00

abstract：:A case of cutaneous Rosai-Dorfman disease (CRDD) presenting as a granulomatous rosacea-like rashs was reported. A 45-year-old Chinese woman presented with a 1-month history of a widespread nonpruiginous papulonodular eruption. The rash had begun on her face and rapidly progressed to involve the neck and extremities. S...

journal_title：Chinese medical journal

authors： Shi XY,Ma DL,Fang K

更新日期：2011-03-01 00:00:00

abstract：:The recurrent rate of herpes simplex keratitis (HSK) was 4.17% after penetrating keratoplasty (PKP) was performed in 216 patients with HSK; the mean period of follow-up was 6.5 years. Immunohistochemical technique showed that HSV-1 antigens were present in the corneal stroma of rabbit eyes up to 45 days after primary ...

journal_title：Chinese medical journal

authors： Xie LX,Dong XG,Kaufman HE

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Vascular endothelial dysfunction is considered a key pathophysiologic process for the development of acute lung injury. In this study, we aimed at investigating the effects of unfractionated heparin (UFH) on the lipopolysaccharide (LPS)-induced changes of vascular endothelial-cadherin (VE-cadherin) and the p...

journal_title：Chinese medical journal

authors： Mu ST,Tang J,Ma JQ,Zhong Y,Liu HZ,Ma XC,Zheng Z

更新日期：2020-08-05 00:00:00

abstract：OBJECTIVE:To determine the in vitro expression of interleukin-12 (IL-12) and its effect on signal transducers and activators of transcription (STAT) signaling molecules in peripheral blood mononuclear cells (PBMCs) in patients with systemic lupus erythematosus (SLE). METHODS:Peripheral blood mononuclear cells in 39 pa...

journal_title：Chinese medical journal

authors： Li Z,Li Y,Huang L,Xu H,Yu X,Ye R

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:The effectiveness of neoadjuvant chemoradiotherapy (NCRT) treatment for patients with esophageal carcinoma (EC) remains controversial. The aim of this study was to compare the effect of NCRT followed by surgery (NCRTS) with surgery alone (SA) for EC. METHODS:The PubMed, EMBASE, and the Cochrane Library data...

journal_title：Chinese medical journal

authors： Wang DB,Sun ZY,Deng LM,Zhu DQ,Xia HG,Zhu PZ

更新日期：2016-12-20 00:00:00

abstract：OBJECTIVE:To detect 3 kinds of N-ras mutations in Chinese patients with acute myeloid leukemia (AML). METHODS:In vitro DNA amplification followed by oligonucleotide dot analysis were used to study N-ras gene mutations in 43 cases of acute myeloid leukemia (AML). 25 healthy people were used as controls. Patients were s...

journal_title：Chinese medical journal

authors： Guo W,Tang B,Xu S,Yao Y,Ye D

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:The heavy incidence and mortality of hemorrhagic fever with renal syndrome, as well as no specific drugs in curing the disease, clearly indicate the need for development of the more effective hantavirus vaccine. Refining the DNA vaccination strategy to elicit more clinically efficacious immune responses is n...

journal_title：Chinese medical journal

authors： Zheng LY,Mou L,Lin S,Lu RM,Luo EJ

更新日期：2005-02-20 00:00:00

abstract：BACKGROUND:There are controversies about the use of artificial colloids. This research was aimed to determine the effect of various artificial colloids on blood coagulation in the shock stage of severe burn injury. METHODS:Totally, 18 female Ba-Ma mini-pigs were subjected to a 40% total body surface third-degree flame...

journal_title：Chinese medical journal

authors： Zhou JJ,Xing N,Chen J,Shi JW,Su GL

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Trichosporon asahii (T. asahii) is one of the most important pathogenic fungus in the genus of trichosporon. Although the species identification of T. asahii was based upon the complicated results of morphologic, biochemical and biologic examination, the morphology characteristic is still the first clue to t...

journal_title：Chinese medical journal

authors： Wang WL,Yang RY,Ao JH

更新日期：2009-08-05 00:00:00

abstract：BACKGROUND:The long-term safety and efficacy of drug-eluting stents (DES) versus bare metal stents (BMS) are unclear and controversial issues in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The purpose of this study was to compare the long-t...

journal_title：Chinese medical journal

authors： Wang CH,Fang Q,Zhang SY,Shen ZJ,Fan ZJ,Jin XF,Zeng Y,Liu ZY,Xie HZ,Yang M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Studies have shown that abnormal activation of the sonic hedgehog pathway is closely related to tumorigenesis in central nervous system. This study aimed to investigate the role of the sonic hedgehog signaling pathway in the occurrence of brainstem and supratentorial glioma. METHODS:Real-time quantitative r...

journal_title：Chinese medical journal

authors： Xin Y,Hao SY,Tian YJ,Zhang JT,Wu Z,Wan H,Li JH,Jiang J,Zhang LW

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The duration of viral shedding and the transmission of 2009 H1N1 influenza among individuals, especially among the younger population with mild illness, are not well understood now. The aim of this study was to determine the viral shedding of the young adult patients with mild 2009 H1N1 influenza in China. ...

journal_title：Chinese medical journal

authors： Jia N,Gao Y,Suo JJ,Xie LJ,Yan ZQ,Xing YB,He L,Liu YX

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:It is important to choose an appropriate antiepileptic drug (AED) to manage partial epilepsy. Traditional AEDs, such as carbamazepine (CBZ) and valproate (VPA), have been proven to have good therapeutic effects. However, in recent years, a variety of new AEDs have increasingly been used as first-line treatme...

journal_title：Chinese medical journal

authors： Zhu F,Lang SY,Wang XQ,Shi XB,Ma YF,Zhang X,Chen YN,Zhang JT

更新日期：2015-11-20 00:00:00

abstract：OBJECTIVE:To compare the efficacy of transcranial Doppler ultrasound (TCD) and digital subtraction angiography (DSA) in identifying the clinical and hemodynamic relationship between intra- and extra-cranial circulation and subclavian steal syndrome. METHODS:Sixteen patients were collected. The intra- and extra-cranial...

journal_title：Chinese medical journal

authors： Huang Y,Gao S,Wang B,Li S

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To characterize effects of the GP Ib alpha mutation (A156V) on its interaction with von Willebrand factor (vWf) under high fluid shear stress. METHODS:The residue A156 of GP Ib alpha was converted to a valine and the mutant expressed in CHO cells expressing wild-type GP Ib beta and GPIX. The transfected cell...

journal_title：Chinese medical journal

authors： Dong J,Li C,Schade AJ,Fredrickson BJ,Sun L,McIntire LV,López JA

更新日期：2000-08-01 00:00:00

abstract：:A series of 146 women taking compound quinestrol (CQ) was tested for glucose tolerance and insulin release to determine the effects of CQ on these parameters. 23 normal subjects (6 male and 17 female) and 12 diabetics (7 male and 5 female) were also tested and their results were compared with those from the CQ-taking...

journal_title：Chinese medical journal

authors： Zhu XX,He DH,Wang ZG,Chen JH,He WT,Qiu CL,Zhong XL

更新日期：1980-09-01 00:00:00

abstract：:Recombinant DNA Yeast-Derived Hepatitis B Vaccine (RYHB vaccine) is comparable to and can replace Plasma-Derived Hepatitis B Vaccine (PHB vaccine) for the prevention of mother-infant transmission of hepatitis B virus (HBV), but the duration of immune efficacy of RYHB vaccine is not clear. This study indicates the long...

journal_title：Chinese medical journal

authors： Zhu QR,Gu XH,Duan SC,Xu HF

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Airway mucus hypersecretion is an important pathophysiological feature of chronic obstructive pulmonary disease, which is closely associated with cigarette smoking. However, the signal transduction pathway from the cell surface to the nucleus through which cigarette smoke causes upregulation of mucin gene ex...

journal_title：Chinese medical journal

authors： Xiao J,Wang K,Feng YL,Chen XR,Xu D,Zhang MK

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To investigate all-trans retinoic acid (ATRA) and As2O3 which were found to be able to selectively induce differentiation and apoptosis in acute promyelocytic leukemia (APL) and recently became standard treatment for de novo or relapsed APL. The results of long-term follow up in 72 APL patients were presented...

journal_title：Chinese medical journal

authors： Hu J,Shen Z,Sun H,Wu W,Li X,Sun G,Wang Z

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Intravascular ultrasound (IVUS) examination can provide useful information during endovascular stent graft repair. However, its actual clinical utility in thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (type B-AD) remains unclear, especially in complicated aortic dissection. We eval...

journal_title：Chinese medical journal

authors： Guo BL,Shi ZY,Guo DQ,Wang LX,Tang X,Li WM,Fu WG

更新日期：2015-09-05 00:00:00

abstract：OBJECTIVE:To induce islet grafting tolerance by intravenous injection of anti-CD4, anti-CD8 immunotoxins and donor soluble antigen. METHODS:Fourteen days or 7 days prior to transplantation, the immunotoxin of anti-CD4, anti-CD8 200 micrograms respectively, and donor soluble antigen 500 micrograms were intravenously in...

journal_title：Chinese medical journal

authors： Lan P,Yan L,Xiao L

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a Th2 dominant cytokine response. Chloride channel-3 (ClC-3) plays an important role in nasal mucosal edema and inflammatory pathologic changes in AR. Antiallergic herbal agents (AHA) are antiallergic herbal products. In the previous study, we have demonstrated that AHA clearly inhi...

journal_title：Chinese medical journal

authors： Wang LF,Xu LJ,Guo FH,Wang LN,Shen XH

更新日期：2010-04-20 00:00:00

abstract：OBJECTIVE:To assess whether Angiotensin II (Ang II) and carbon tetrachloride (CCl(4)) used in combination could accelerate the process of fibrosis and whether Ang II play a role in exagerating hepatic fibrosis in rats. METHODS:Ang II was injected into the abdominal cavity of Sprague-Dawley (SD) rats together with subc...

journal_title：Chinese medical journal

authors： Zhou X,Li D,Li X,Lu H,Zhang W

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The incidence of no reflow phenomenon limits the clinical outcomes of percutaneous coronary intervention (PCI). This randomized controlled study was designed to evaluate the immediate protective effects of intensive statin pretreatment on myocardial perfusion and myocardial ischemic injury during PCI. METHO...

journal_title：Chinese medical journal

authors： Jia XW,Fu XH,Zhang J,Gu XS,Fan WZ,Wu WL,Hao GZ,Li SQ,Jiang YF

更新日期：2009-03-20 00:00:00

abstract：BACKGROUND:There are few reports of microsurgical treatment of dorsum sellae meningiomas-which, because of location, size, and differences in growth direction, clinical presentations, degree of surgical difficulty, have varied posttreatment sequelae. In pursuit of an optimal microsurgical treatment option for dorsum se...

journal_title：Chinese medical journal

authors： Geng SM,Zhang JT,Zhang LW,Wu Z,Wang ZC

更新日期：2009-08-20 00:00:00

abstract：BACKGROUND:Although obstructive sleep apnea (OSA) has been recognized as a major risk factor for cardiovascular complications and its clinical features are well characterized, it is difficult to replicate the OSA hypoxic model in humans. We aimed to establish an experimental rabbit model for chronic OSA and to explore ...

journal_title：Chinese medical journal

authors： Xu LF,Zhou XF,Hu K,Tang S,Luo YC,Lu W

更新日期：2017-02-20 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infe...

journal_title：Chinese medical journal

authors： Xue L,Luo S,Luo J,Liu Z,Gu M,Kang H,Yang F,Nie B,Liu Y,Huang W,Xie N,He P,Dong H,Ni Z,Fan R,Chen J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Myoglobin is expressed exclusively in striated skeletal muscles and has been implicated in nitric oxide scavenging. Accumulating data suggest a critical role for nitric oxide in both the endogenous and therapeutic angiogenic response to ischemia. A clear role for myoglobin in ischemic skeletal muscle is unce...

journal_title：Chinese medical journal

authors： Yang YG,Guan H,Liu CW,Li YJ

更新日期：2009-05-05 00:00:00