Expression of interleukin-12 and its signaling molecules in peripheral blood mononuclear cells in systemic lupus erythematosus patients.

abstract：BACKGROUND:Acute lung injury (ALI) and end-stage acute respiratory distress syndrome (ARDS) were among the most common causes of death in intensive care units. The activation of an inflammatory response and the damage of pulmonary epithelium and endotheliumwerethe hallmark of ALI/ARDS. Recent studies had demonstrated t...

journal_title：Chinese medical journal

authors： Xu YL,Liu YL,Wang Q,Li G,Lü XD,Kong B

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:One of the major causes of death in severe acute pancreatitis (SAP) is severe infection owing to bacterial translocation. Some clinical studies suggested that ecoimmunonutrition (EIN) as a new strategy had better treatment effect on SAP patients. But the experiment studies on the precise mechanism of the eff...

journal_title：Chinese medical journal

authors： Xu GF,Lu Z,Gao J,Li ZS,Gong YF

更新日期：2006-04-20 00:00:00

abstract：BACKGROUND:Four single nucleotide polymorphisms (SNPs) in the modulator recognition factor 2/AT-rich interaction domain 5B (MRF2/ARID5B) gene located at chromosome 10q21.2 have been shown to be associated with both type 2 diabetes mellitus (T2DM) and coronary artery disease in a Japanese cohort. This study aimed to inv...

journal_title：Chinese medical journal

authors： Sun LL,Zhang SJ,Chen MJ,Elena K,Qiao H

更新日期：2017-05-05 00:00:00

abstract：BACKGROUND:Smoking is the major cause of airway inflammation in chronic obstructive pulmonary disease (COPD), and smoking cessation is regarded as one of the important strategies for prevention and treatment of the inflammation. The inflammation of the chronic airway may be present and deteriorated even if the COPD pat...

journal_title：Chinese medical journal

authors： Li QY,Huang SG,Wan HY,Wu HC,Zhou T,Li M,Deng WW

更新日期：2007-09-05 00:00:00

abstract：OBJECTIVE:To evaluate the human neuroblastoma SH-SY5Y cell line as an in vitro model of dopaminergic (DAergic) neurons for Parkinson's disease (PD) research and to determine the effect of differentiation on this cell model. DATA SOURCES:The data of this review were selected from the original reports and reviews relate...

journal_title：Chinese medical journal

authors： Xie HR,Hu LS,Li GY

更新日期：2010-04-20 00:00:00

abstract：:The surface structure of four different articular cartilages of the femoral head was studied with scanning electron microscope in 12 cases of hip joint osteoarthritis. These articular cartilages were mink white, yellow, dusky red and hyperplastic and thickened. The osteoarthritic articular cartilage surface was uneven...

journal_title：Chinese medical journal

authors： Chai BF,Tang XM

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:In the era of highly active antiretroviral therapy (HAART), the use of antiretrovirals as post-exposure prophylaxis (PEP) was the most important strategy for preventing occupational exposure to blood or fluids containing human immunodeficiency virus (HIV). The objective of this study was to retrospectively e...

journal_title：Chinese medical journal

authors： Cai J,Xiao J,Zhang Q

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus plays an important role in cancer prevalence and outcomes. The aim of this study was to evaluate the influence of DM on stages and outcomes among patients with colorectal cancer. METHODS:The study enrolled 945 patients who were diagnosed as having colorectal carcinoma from August 1994 to D...

journal_title：Chinese medical journal

authors： Chen CQ,Fang LK,Cai SR,Ma JP,Yang GX,Yang W,Zhan WH,He YL

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:According to the characteristics of digital medicine and the demands of digitalized management in hospitals, we established a storage system that is affordable, highly expandable, and reliable. METHODS:The multi personal computer storage system (MPCSS) was constructed using hardware and software. The image d...

journal_title：Chinese medical journal

authors： Guo Q,Hao F,Duan X,Xie X,Liao W

更新日期：2003-05-01 00:00:00

abstract：:Patients whose routine MRI were negative but were clinically highly suspected of having intra-cranial or intra-spinal canal space-occupying lesions, and those whose routine MRI were positive but presented difficulties in defining the contour or the nature of the lesion, or difficulty in distinguishing the lesion from ...

journal_title：Chinese medical journal

authors： Shen TZ,Mei H,Huang XL,Chen XR

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:To improve the prognosis and therapeutic efficacy of Waldeyer's ring non-Hodgkin lymphoma (NHL-WR), combined radio-chemotherapy was used to treat the patients with NHL-WR and prognostic factors were analyzed. METHODS:Ninety patients with stage I-IV NHL-WR were treated with combined radio-chemotherapy. 4000 c...

journal_title：Chinese medical journal

authors： Yong W,Zhang Y,Zheng W,Wei Y

更新日期：2000-02-01 00:00:00

abstract：:Since 1979 we have treated 149 patients with duodenal ulcer by extended parietal cell vagotomy (EPCV). Electron microscopy of parietal cells from gastric body mucosa and gastric acid secretory test were carried out in 22 randomly selected patients before and after EPCV. It was shown that before EPCV the ultrastructure...

journal_title：Chinese medical journal

authors： Li S,Chen P,An P,Liu C,Yuan S,Chen L

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Endothelial cells derived microRNAs can be detected in plasma and serum and there is evidence that inflammatory disease states may affect the levels of circulating microRNAs. However, there is no direct proof that inflammation induces endothelial cells to release microRNAs into circulation. This study aimed ...

journal_title：Chinese medical journal

authors： Zhang J,Ren J,Chen H,Geng Q

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Studies on selected patients undergoing off-pump versus on-pump coronary artery bypass surgery have produced inconsistent results, especially in patients with multiple coronary artery disease. This study compared the clinical results of on-pump and off-pump coronary bypass surgery in patients with triple-ves...

journal_title：Chinese medical journal

authors： Chen X,Xu M,Shi HW,Mu XW,Chen ZQ,Qiu ZB

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PCI) is the best treatment of choice for acute ST segment elevation myocardial infarction (STEMI). This study aimed to determine the clinical outcomes of tirofiban combined with the low molecular weight heparin (LMWH), dalteparin, in primary PCI patients with acute...

journal_title：Chinese medical journal

authors： Li WM,Yang XC,Wang LF,Ge YG,Wang HS,Xu L,Ni ZH,Zhang DP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-α is a key mediator in the pathogenesis of psoriasis. Infliximab is a monoclonal antibody that specifically binds to tumor necrosis factor-α. The purpose of this study was to validate the efficacy and safety of 5 mg/kg infliximab therapy in Chinese patients with moderate to severe plaqu...

journal_title：Chinese medical journal

authors： Yang HZ,Wang K,Jin HZ,Gao TW,Xiao SX,Xu JH,Wang BX,Zhang FR,Li CY,Liu XM,Tu CX,Ji SZ,Shen Y,Zhu XJ

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

journal_title：Chinese medical journal

authors： Zhou Z,Li L,Yu Y,Ma Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The mitochondrial displacement loop (D-loop) accumulates mutations and single nucleotide polymorphisms (SNPs) at a higher frequency than other regions of mitochondrial DNA (mtDNA). We previously identified disease risk-associated SNPs in the D-loop of chronic kidney disease (CKD) patients; in this study, we ...

journal_title：Chinese medical journal

authors： Bai Y,Guo Z,Xu J,Zhang J,Cui L,Zhang H,Zhang S,Ai X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The precise pathophysiology of venous erectile dysfunction (VED) was still unclear. Dynamic infusion cavernosometry and cavernosography (DICC) was the gold standard approach for the diagnoses of VED. However, a standard operative procedure of DICC was needed and it was unclear whether DICC could show promise...

journal_title：Chinese medical journal

authors： Gao QQ,Chen JH,Chen Y,Song T,Dai YT

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Our previous research has suggested that genes around D12S1056 in 12q13 may confer susceptibility to ventricular septal defect (VSD) in humans. The present study was to define the chromosome region assignment by transmission disequilibrium test (TDT), and to identify the important candidate gene by family-ba...

journal_title：Chinese medical journal

authors： Qiu GR,Gong LG,He G,Xu XY,Xin N,Sun GF,Yuan YH,Sun KL

更新日期：2006-02-20 00:00:00

abstract：BACKGROUND:Roundabout 5 (R5) is a monoclonal antibody which can neutralize the binding of Roundabout 1 (Robo1) to Slit2. Oral squamous cell carcinoma angiogenesis was significantly inhibited when R5 blocked slit-robo signaling pathway. However, the effect of R5 on the invasion of tongue cancer cells has not been invest...

journal_title：Chinese medical journal

authors： Xiao R,Zhao Y,Wang LJ,Li WP

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:We assessed whether the CaNa2 EDTA could improve the accumulation of protoporphyrin IX (PpIX) and photosensitisation in HEp-2 cells as well as the depth of treatment of skin cancers on the topical 5-Aminolaevulinic acid (5-ALA) PDT. METHODS:HEp-2 cells were incubated with 5-ALA (0-1 mmol/L) and CaNa2EDTA (0...

journal_title：Chinese medical journal

authors： Liu HF,Xu SZ,Zhang CR

更新日期：2004-06-01 00:00:00

abstract：Background:Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening clinical syndrome. Central nervous system (CNS) involvement is a severe complication, which can lead to rapid disease development and higher morality. However, this has not been given enough attention in adult HLH. Therefore, we carried out this ...

journal_title：Chinese medical journal

authors： Song Y,Pei RJ,Wang YN,Zhang J,Wang Z

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:Primary percutaneous coronary intervention (PCI) has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction (STEMI). The strategy of transferring patient to a PCI center was recently recommended for those with acute STEMI who were present to PCI inc...

journal_title：Chinese medical journal

authors： Zhang Q,Zhang RY,Qiu JP,Zhang JF,Wang XL,Jiang L,Liao ML,Zhang JS,Hu J,Yang ZK,Shen WF

更新日期：2008-03-20 00:00:00

abstract：:Metastases to the breast from extramammary neoplasms are very rare, constituting 2.7% of all malignant breast tumours. The most common primary tumor metastatic to the breast is primary breast cancer. Rectal cancer metastasizing to the breast is extremely rare. We report a case of aggressive rectal carcinoma with metas...

journal_title：Chinese medical journal

authors： Li J,Fang Y,Li A,Li F

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Gastric intestinal metaplasia (GIM) is generally considered to be the main mucosal background for the development of gastric adenocarcinomas. Using linked color imaging (LCI), we noticed that the color pattern in areas of GIM was purple mixed with white on the epithelium with signs of mist that were detected...

journal_title：Chinese medical journal

authors： Min M,Dong TH,Liu Y,Bi YL,Ma CY

更新日期：2019-04-05 00:00:00

abstract：:This is China's pilot study in the assessment of the diagnostic value of serum soluble IL-2 receptor (sIL-2R) in gastric cancer. We measured its level by ELISA method in 45 patients with gastric cancer (without metastasis: 32; with metastasis: 5; recurrence: 8) 27 gastric ulcer, 27 superficial gastritis and 44 healthy...

journal_title：Chinese medical journal

authors： Wang YF,Wu XN,Zhou YH,Chen XF,Shen J,Wang HJ

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:It has been confirmed that defective expression of human leukocyte antigen class I (HLA-I) molecules can contribute to the immune evasion of cancer cells in some types of cancer. The aim of this study was to examine the expression of HLA class I antigen and the antigen-processing machinery (APM) components i...

journal_title：Chinese medical journal

authors： Ayshamgul H,Ma H,Ilyar S,Zhang LW,Abulizi A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical value of sequential subtraction scintigraphy (SSS) with 99mTc red blood cell (RBC) for the early detection of gastrointestinal (GI) bleeding. METHODS:Ninety patients referred with clinical evidence of GI bleeding underwent 99mTc-RBC scintigraphy with digital gamma camera after labeli...

journal_title：Chinese medical journal

authors： Wu Y,Seto H

更新日期：2001-01-01 00:00:00

abstract：Background:Endometriosis is a challenging disease with symptoms such as dysmenorrhea and infertility. However, its etiology is still vague and there is still no effective markers or treatment. This study aimed to profile the circular RNAs (circRNAs) expressed in eutopic endometrium from patients with ovarian endometrio...

journal_title：Chinese medical journal

authors： Xu XX,Jia SZ,Dai Y,Zhang JJ,Li XY,Shi JH,Leng JH,Lang JH

更新日期：2018-03-05 00:00:00