Expression and significance of sonic hedgehog signaling pathway-related components in brainstem and supratentorial astrocytomas.

abstract：OBJECTIVES:To analyze the FBN1 mutations in Chinese patients with Marfan syndrome (MFS) and to make a genetic diagnosis based on haplotype linkage analysis for MFS. METHODS:Nine MFS families (17 patients) were analyzed with single strand conformation polymorphism (SSCP) and sequencing. Four primers were designed for t...

journal_title：Chinese medical journal

authors： Wang B,Hu D,Xia J,Li Q,Yang J,Lu G

更新日期：2003-07-01 00:00:00

abstract：Background:Facioscapulohumeral muscular dystrophy (FSHD) is characterized by asymmetric muscular deficit of facial, shoulder-girdle muscles, and descending to lower limb muscles, but it exists in several extramuscular manifestations or overlapping syndromes. Herein, we report a "complex disease plus" patient with FSHD1...

journal_title：Chinese medical journal

authors： Lin XD,He JJ,Lin F,Chen HZ,Xu LQ,Hu W,Cai NQ,Lin MT,Wang N,Wang ZQ,Xu GR

更新日期：2018-09-20 00:00:00

abstract：:A patient with both a femoral attachment injury (peel-off injury) and musculotendinous junction avulsion of the popliteus, a so-called “floating popliteus tendon injury”, received arthroscopy-assisted popliteus reconstruction. The injured ligaments were addressed in the same procedure, including mini-open direct repai...

journal_title：Chinese medical journal

authors： Zhang J,Feng H,Hong L,Wang XS,Zhang H

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To study the potential and advantages of internal distraction osteogenesis in mandibular functional reconstruction. METHODS:Three types of mandibular distractors were used in eight patients with various mandibular defects due to tumor or cyst resection. The average age of the patients was 31.5 years old (age...

journal_title：Chinese medical journal

authors： Wang X,Lin Y,Yi B,Wang X,Liang C,Li Z

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The offspring of women with gestational diabetes mellitus (GDM) are prone to macrosomia. However, birth weight is difficult to be correctly estimated by ultrasound because of fetal asymmetric growth characteristics. This study aimed to investigate the correlations between fetal hemodynamics, fetal growth ind...

journal_title：Chinese medical journal

authors： Liu F,Liu Y,Lai YP,Gu XN,Liu DM,Yang M

更新日期：2016-09-05 00:00:00

abstract：OBJECTIVE:To choose one optimal extrinsic positive end-expiratory pressure (PEEPe) for ventilated patients with chronic obstructive pulmonary disease (COPD) and to compare two methods for choosing the optimal level of PEEPe. METHODS:Ten ventilated patients with COPD were included in the study. First, static intrinsic ...

journal_title：Chinese medical journal

authors： Kong W,Wang C,Yang Y,Huang K,Jiang C

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Orthotopic liver transplantation (OLT) has become the therapeutic option of choice for end-stage liver disease. The aim of this study was to investigate the changes of splenic morphology, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), apparent diffusion coefficient (ADC) values and explore their...

journal_title：Chinese medical journal

authors： Wang J,Liang Y,Yan R,Jiang Z,Liu J,Hu B,He B,Ren L,Chen J,Shan H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To clarify the role of these cyclins in human gastric cancer. METHODS:38 gastric cancer patients, 29 first degree relatives of gastric cancer patients, as well as 18 healthy subjects were included. The mRNA expression of cyclins D1, D2, D3 and E in gastric biopsies was evaluated by RT-PCR analysis using spec...

journal_title：Chinese medical journal

authors： Yu J,Miehlke S,Ebert MP,Szokodi D,Wehvnignh B,Malfertheiner P,Ehninger G,Bayerdoerffer E

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Severe valgus deformity often has bone defect and laxity of the medial ligamentous, and total knee arthroplasty in severe valgus knee is, in most cases, more challenging for surgeons. The usefulness of a computer assisted navigation system in reestablishing the mechanical axis has been well established. Henc...

journal_title：Chinese medical journal

authors： Shao JJ,Zhang XL,Wang Q,Chen YS,Shen H,Jiang Y

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The most important objective of transplant studies in the injured spinal cord has been to provide a favorable environment for axonal growth. Moreover, the continuing discovery of new grafts is providing new potentially interesting transplant candidates. Our purpose was to observe the morphological and functi...

journal_title：Chinese medical journal

authors： Chen G,Hu YR,Wan H,Xia L,Li JH,Yang F,Qu X,Wang SG,Wang ZC

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features, operative methods and postoperative management of the intra-axial tumors of medullocervical junction, and to make differential diagnosis for different subtypes. METHODS:Fifteen patients with intra-axial tumors of medullocervical junction were treated from August 1988 to Jun...

journal_title：Chinese medical journal

authors： Xu Q,Bao W,Mao R,Pang L

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:There are controversies about the use of artificial colloids. This research was aimed to determine the effect of various artificial colloids on blood coagulation in the shock stage of severe burn injury. METHODS:Totally, 18 female Ba-Ma mini-pigs were subjected to a 40% total body surface third-degree flame...

journal_title：Chinese medical journal

authors： Zhou JJ,Xing N,Chen J,Shi JW,Su GL

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To determine the relationships of Met416Val and XbaI polymorphism of muscle glycogen synthase (GYS1) gene and Trg64Arg variant of the beta(3)-adrenergic-receptor (beta(3)-AR) gene with type 2 diabetes mellitus (DM) and its intermediate phenotypes in the Chinese population. METHODS:Polymerase chain reaction-o...

journal_title：Chinese medical journal

authors： Wang G,Li Q,Niu T,Chen C,Xu X

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Although there were several clinical and experimental studies discussing the pathogenesis of dural arteriovenous fistula (DAVF), the pathological process leading to intracranial DAVF so far remains unknown. In this study, we investigated the expression of vascular growth factors in order to elucidate the pos...

journal_title：Chinese medical journal

authors： Tirakotai W,Bian LG,Bertalanffy H,Siegfried B,Sure U

更新日期：2004-12-01 00:00:00

abstract：:Somatosensory evoked potentials (SEP) arising from median nerve stimulation were recorded in 102 patients with unilateral cerebral hemorrhage or infarct located in basal ganglion, internal capsule, thalamus or cerebral lobe. Of them 42 cases were followed up and reexamined with SEPs. Three types of SEPs were observed:...

journal_title：Chinese medical journal

authors： Lu ZN,Yu SZ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Recurrence or metastasis of myxomas is not rare and can lead to malignancy. We aimed to analyze the risk factors for postoperative cardiac myxoma recurrence and to summarize its clinical characteristics, treatments and classification. METHODS:The clinical data of 5 patients with recurrent cardiac myxoma wer...

journal_title：Chinese medical journal

authors： Sheng WB,Luo BE,Liu Y,Zhang H,Zou LJ,Xu ZY,Zhang HY,Ji GY

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:HATCH score is an established predictor of progression from paroxysmal to persistent atrial fibrillation (AF). The purpose of this study was to determine if HATCH score could predict recurrence after catheter ablation of AF. METHODS:The data of 488 consecutive paroxysmal AF patients who underwent an index c...

journal_title：Chinese medical journal

authors： Tang RB,Dong JZ,Long DY,Yu RH,Ning M,Jiang CX,Sang CH,Liu XH,Ma CS

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a Th2 dominant cytokine response. Chloride channel-3 (ClC-3) plays an important role in nasal mucosal edema and inflammatory pathologic changes in AR. Antiallergic herbal agents (AHA) are antiallergic herbal products. In the previous study, we have demonstrated that AHA clearly inhi...

journal_title：Chinese medical journal

authors： Wang LF,Xu LJ,Guo FH,Wang LN,Shen XH

更新日期：2010-04-20 00:00:00

abstract：OBJECTIVE:To determine the distribution of aortic arch and intra/extracranial cerebral arterial atherosclerosis in Chinese patients who had suffered acute ischemic strokes. METHODS:Eighty-nine patients with acute ischemic strokes were included in this study. Transesophageal echocardiography (TEE) was used to evaluate ...

journal_title：Chinese medical journal

authors： Guo Y,Jiang X,Chen S,Zhang S,Zhao H,Wu Y

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:With features of high tissue contrast, MRI can be used for the qualitative and quantitative evaluation of atherosclerosis plaques. In this study we investigated the development of atherosclerosis plaque with high resolution 3T MRI in a rabbit model and compared the findings with the histopathological results...

journal_title：Chinese medical journal

authors： Ma XH,Zhao L,Zhao QM,Feng TT,Shang JF,Zhang ZQ

更新日期：2012-08-01 00:00:00

abstract：Objective:Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago, enormous progress has been made in stem cell biology and regenerative medicine. Human iPSCs have been widely used for disease modeling, drug discovery, and cell therapy development. In this review, we discuss the progress in app...

journal_title：Chinese medical journal

authors： Wang F,Kong J,Cui YY,Liu P,Wen JY

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:Although some studies have reported that aquaporin-4 (AQP4) plays a role in the post-ischemic edema formation and diffusion-weighted imaging (DWI), little is known about the AQP4 expression in stage of the reperfusion following acute cerebral ischemia, as well as the correlation between histopathology and DW...

journal_title：Chinese medical journal

authors： Lu H,Hu H,He ZP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Visfatin, a visceral fat-derived adipocytokine, plays a significant physiological function in lipid metabolism. However, the precise function of visfatin and its regulation by thyroid hormones are still unknown. This study observed the plasma visfatin concentrations in subjects with hyperthyroidism and hypot...

journal_title：Chinese medical journal

authors： Han J,Zhang TO,Xiao WH,Chang CQ,Ai H

更新日期：2012-03-01 00:00:00

abstract：:A study was made in Neijiang City, Sichuan Province to observe the safety and immunogenicity of a live attenuated hepatitis A virus (HAV) vaccine (H2 strain). 3,031 children, aged 6 to 9 years, were injected subcutaneously with 10(6.0) TCID50, 10(5.5) TCID50, and 10(5.0) TCID50 of HAV vaccine; the seroconversion rate ...

journal_title：Chinese medical journal

authors： Ran LA,Wang DZ,Duan QY,Yan TY,Liu QL,Luo YG,Yang DZ,Yang DF,Xiao Z,Xie QJ

更新日期：1993-08-01 00:00:00

abstract：:With overall analysis of symptoms and signs of myasthenia gravis (MG) basing on "Pi (Spleen) Deficiency" [symbol: see text] theory and with years of our clinical experience in treating MG, we performed a pharmacological study of Astragalus saponins and Buzhong Yiqi Compound (Tonic granulae invigorating vital energy) i...

journal_title：Chinese medical journal

authors： Tu LH,Huang DR,Zhang RQ,Shen Q,Yu YY,Hong YF,Li GH

更新日期：1994-04-01 00:00:00

abstract：Background:Automated peritoneal dialysis (APD) can cater to individual needs, provide treatment while asleep, take into account the adequacy of dialysis, and improve the quality of life. Currently, independent research and development of APD machines made in China are more conducive to patients. A randomized, multicent...

journal_title：Chinese medical journal

authors： Cao XY,He YN,Zhou JH,Sun SR,Miao LN,Chen W,Fang JA,Wang M,Wang NS,Lin HL,Liu J,Ni ZH,Liu WH,Na Y,Zhao JY,Guo ZY,Zheng HG,Shi W,Jiang GR,Cai GY,Chen XM

更新日期：2018-12-05 00:00:00

abstract：BACKGROUND:Ischemic disease is one of the leading causes of death in the world. In order to further study gene therapy for ischemic disease, we constructed a recombinant plasmid for co-expression of human angiopoietin-1 and vascular endothelial growth factor 165(VEGF165) gene in adeno-associated virus (AAV) gene delive...

journal_title：Chinese medical journal

authors： Chen DJ,Tan Z,Xie YL,Liu F

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:Secreted modular calcium-binding proteins (SMOCs) are extracellular glycoproteins of the secreted protein, acidic, and rich in cysteine-related modular calcium-binding protein family and include two isoforms, SMOC1 and SMOC2, in humans. Functionally, SMOCs bind to calcium for various cell functions. In this r...

journal_title：Chinese medical journal

authors： Gao Q,Mok HP,Zhuang J

更新日期：2019-10-20 00:00:00

abstract：BACKGROUND:Trichosporon asahii (T. asahii) is one of the most important pathogenic fungus in the genus of trichosporon. Although the species identification of T. asahii was based upon the complicated results of morphologic, biochemical and biologic examination, the morphology characteristic is still the first clue to t...

journal_title：Chinese medical journal

authors： Wang WL,Yang RY,Ao JH

更新日期：2009-08-05 00:00:00

abstract：BACKGROUND:Pulmonary problems often occur in patients with early-onset scoliosis (EOS). However, lung function in patients with EOS after growing rod surgery has not been documented. The aim of this study was to investigate lung function after the treatment for EOS with growing rod and its possible correlative factors....

journal_title：Chinese medical journal

authors： Jiang Y,Zhao Y,Wang YP,Qiu GX,Weng XS,Li Y

更新日期：2011-12-01 00:00:00