Safety and immunogenicity of live attenuated hepatitis A virus vaccine (H2 strain) in humans.

abstract：OBJECTIVE:To study the relationship between cartilage end-plate calcification and intervertebral disc degeneration. METHODS:An experimental model of cervical disc degeneration in rabbits was established by resection of the cervical supraspinous and interspinous ligaments and detachment of the posterior paravertebral m...

journal_title：Chinese medical journal

authors： Peng B,Hou S,Shi Q,Jia L

更新日期：2001-03-01 00:00:00

abstract：:The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widene...

journal_title：Chinese medical journal

authors： Dai LY,Jia LS

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:To investigate all-trans retinoic acid (ATRA) and As2O3 which were found to be able to selectively induce differentiation and apoptosis in acute promyelocytic leukemia (APL) and recently became standard treatment for de novo or relapsed APL. The results of long-term follow up in 72 APL patients were presented...

journal_title：Chinese medical journal

authors： Hu J,Shen Z,Sun H,Wu W,Li X,Sun G,Wang Z

更新日期：2000-02-01 00:00:00

abstract：:Microencapsules for pituitary transplantation was successfully developed with sodium alginate and poly-L-lysine (average molecular weight MW 70,000). The permeability of the capsular membrane (CM) was tested. The results showed that 60% of growth hormone (GH), thyroid stimulating hormone (TSH), prolactin (PRL) have pa...

journal_title：Chinese medical journal

authors： Chen ZP,Bao YD

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To determine antiganglioside antibodies (AGA) in cerebrospinal fluid (CSF) of children with neuropsychiatric lupus erythematosus (NPLE), and to investigate their association with clinical manifestations and other laboratory tests. METHODS:An enzyme linked immunoabsorbent assay was used to detect AGA in 22 CS...

journal_title：Chinese medical journal

authors： Chen Y,Wu F,Hou L,Ma S,He X

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Double plate osteosynthesis is the standard treatment for intra-articular fractures of the distal humerus. However, there is still controversy concerning dual plate positions in terms of providing optimal stability. The purpose of this retrospective study was to compare the clinical outcomes in patients with...

journal_title：Chinese medical journal

authors： Lan X,Zhang LH,Tao S,Zhang Q,Liang XD,Yuan BT,Xu WP,Yin P,Tang PF

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To investigate the compositions of Th1/Th2/Th3 cells in chronic hepatitis B virus (HBV)-infected individuals by determining the expression of interleukin-4 (IL-4), inetrferon-gamma (IFN-gamma), and transform growth factor-beta (TGF-beta) in single CD4(+) T cells isolated from peripheral blood mononuclear cell...

journal_title：Chinese medical journal

authors： Jiang R,Feng X,Guo Y,Lu Q,Hou J,Luo K,Fu N

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Atypical meningioma is one of the rare subtypes of meningioma, which is lacking of optimal consensus on treatment strategies. This study aimed to investigate the radical treatment strategies to improve the long-term outcome of recurrent atypical meningiomas. METHODS:The prognostic factors including the age ...

journal_title：Chinese medical journal

authors： Li F,Lai ZP,Lin JK,Zhu G,Feng H

更新日期：2011-08-01 00:00:00

abstract：:Cerebral cysticercosis is the most common worldwide parasitic infection of the central nervous system. Intraventricular involvement is apparent in 15% to 28.8% of cases with neural compartment infestation.' Although different forms of the disease (parenchymatous, subarachnoid, and mixed form ) have been treated succes...

journal_title：Chinese medical journal

authors： Zhu L,Weng X,Shi Y,Pan X,Mo L

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Knowledge about factors influencing the prognosis of resective epilepsy surgery can be used to identify which patients are most suitable for surgical treatment. The aim of this study was to identify preoperative prognostic factors associated with the chance of achieving long-term seizure freedom. METHODS:We...

journal_title：Chinese medical journal

authors： Yang XL,Lu QC,Xu JW,Wang GS,Liu Q

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To explore the pathogenesis of glucose metabolic disorder and insulin resistance in critically ill children under severe stress. METHODS:To test glucose, lactate, glucagon, insulin, c-peptide, cortisol levels in 50 critically ill children. While we measured 125I-insulin binding to erythrocytes of 13 critical...

journal_title：Chinese medical journal

authors： Xu F,Yang X,Lu Z,Kuang F

更新日期：1996-10-01 00:00:00

abstract：:An epidemiological study on the incidence and prevalence of Parkinson's disease (PD) was carried out in 29 provinces, cities and autonomous regions in this country in 1986. The survey was conducted in 117 areas, and 566 patients with PD were found among 3,869,162 persons examined, giving a point prevalence for men and...

journal_title：Chinese medical journal

authors： Wang YS,Shi YM,Wu ZY,He YX,Zhang BZ

更新日期：1991-11-01 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Zeng XX,Liu J,Ma L,Fu P

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Angiopoietin-2 (Ang-2) is one of the critical regulators of tumor angiogenesis. Studies have shown a significant correlation of Ang-2 expression to tumor invasion and metastasis in various human cancers, but little is known about the serum Ang-2 (sAng-2) levels in esophageal squamous cell cancer (ESCC) and i...

journal_title：Chinese medical journal

authors： Zhou YZ,Fang XQ,Li H,Diao YT,Yang YF,Zhao DL,Wu K,Li HQ

更新日期：2007-07-20 00:00:00

abstract：OBJECTIVE:A human promyelocytic leukemia (APL) cell line NB4 was used to demonstrate the synergistic effects between all-trans retinoic acid (ATRA) and prostaglandin E2 (PGE2) on growth inhibition and cytodifferentiation induction. METHODS:NB4 cells were cultured in the presence of either ATRA or PGE2 as a single agen...

journal_title：Chinese medical journal

authors： Chen Z,Breitman TR

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Phosphorous magnetic resonance spectroscopy ((31)P-MRS) has been successfully applied to study intracellular membrane compounds and high-energy phosphate metabolism. This study aimed to evaluate the capability of dynamic (31)P-MRS for assessing energy metabolism and mitochondrial function in skeletal muscle ...

journal_title：Chinese medical journal

authors： Wu FY,Tu HJ,Qin B,Chen T,Xu HF,Qi J,Wang DH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2), one of the major metabolites from prostaglandin D2 in arachidonic acid metabolic pathway, has potential anti-inflammatory properties. The objective of this study was to explore the effects of 15d-PGJ2-loaded poly(D,L-lactide-co-glycolide) nanocapsules (15d-PGJ2-NC...

journal_title：Chinese medical journal

authors： Tang Q,Chen LL,Wei F,Sun WL,Lei LH,Ding PH,Tan JY,Chen XT,Wu YM

更新日期：2017-02-05 00:00:00

abstract：:Using ambulatory electrocardiography (AE), the spontaneous variability in 40 cases of chronic stable premature ventricular complexes (PVCs) was studied. The mean hourly PVC frequencies over 24 hours ranged 2-1 682. When analysing pooled data, there was significant variance between different monitoring periods and betw...

journal_title：Chinese medical journal

authors： Dai CZ,Zhang YL,Zeng B,Lu YX

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Retinol binding protein 4 (RBP4), as an adipocyte secreted cytokine, was recently found to be inversely correlated with expression of glucose transporter 4 (GLUT4) in insulin resistance (IR) state and to have an intimate relationship with IR and type 2 diabetes mellitus (T2DM). The present study aimed to eva...

journal_title：Chinese medical journal

authors： Zhang W,Xu YC,Guo FJ,Meng Y,Li ML

更新日期：2008-11-05 00:00:00

abstract：BACKGROUND:Cartilage injury has a very poor capacity for intrinsic regeneration. The cell-based treatment strategy for the cartilage repair using differentiated bone marrow mesenchymal stem cells (BMSCs) is, however, a promising approach to the chondral repair. This study was aimed to explore the chondrogenic potential...

journal_title：Chinese medical journal

authors： Li JW,Guo XL,He CL,Tuo YH,Wang Z,Wen J,Jin D

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Serum expression of cytokines may provide information about the clinical outcome of advanced non-small cell lung cancer (NSCLC) patients. This study aimed to investigate the relationship between serum cytokine levels and the clinical outcome of erlotinib treatment in a second or third line setting in patient...

journal_title：Chinese medical journal

authors： Wang YS,Miao LY,Liu L,Cai HR,Ding JJ,Ren SX,Zhou CC,Schmid-Bindert G

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Personalized medicine becomes essential in lung cancer treatment, however lung-cancer-related gene expression profiles in Chinese patients remain unknown. In this study, the correlation of gene expression profiles and clinical characteristics in non-small-cell lung cancer (NSCLC) was investigated. METHODS:S...

journal_title：Chinese medical journal

authors： Yu D,Li J,Han Y,Liu S,Xiao N,Li Y,Sun X,Liu Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The expression of TES, a novel tumor suppressor gene, is found to be down-regulated in the left anterior descending aorta of patients with coronary artery disease (CAD) compared with non-CAD subjects. This study aimed to investigate the expression of TES during the development of atherosclerosis in rabbits. ...

journal_title：Chinese medical journal

authors： Zhang Y,Yuan M,Li HM,Lao M,Xu Z,Li GP

更新日期：2015-06-20 00:00:00

abstract：OBJECTIVE:To provide epidemiological data for revising the diagnostic criteria of neonatal hyperbilirubinemia in China. METHODS:A survey was performed among full-term infants in multiple centers throughout the country. From less than 24 hours after birth, the infants' bilirubin levels were measured every day until the...

journal_title：Chinese medical journal

authors： Ding G,Zhang S,Yao D,Na Q,Wang H,Li L,Yang L,Huang W,Wang Y,Xu J

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:This article aims to present a brief profile of the advances in prevention and treatment of myocardial injury in cancer therapy based on relevant literature or reports. DATA SOURCES:The data cited in this review were obtained from articles indexed in PubMed and China National Knowledge Internet (CNKI) up to ...

journal_title：Chinese medical journal

authors： Miao JX,Gao S,Fan L,Cao F

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:The postremission therapies for adult patients generally contain consolidation chemotherapy, allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell transplantation (auto-HSCT). Because of the various results from different centers, the optimal therapy for adult acute lympho...

journal_title：Chinese medical journal

authors： Ding Z,Han MZ,Chen SL,Ma QL,Wei JL,Pang AM,Zhang XY,Liang C,Yao JF,Cao YG,Feng SZ,Jiang EL

更新日期：2015-08-05 00:00:00

abstract：:Carbamyl phosphate synthetase I (CPS1) is an initial enzyme of urea synthetase system. It exists exclusively in liver cells and epithelial cells of the small intestine. By immunocytochemistry, 70.5% of 88 surgically resected gastric carcinomas (42 advanced and 46 early gastric carcinomas) was found to be CPS1 immunore...

journal_title：Chinese medical journal

authors： Liu TH,Li DC,Gu CF,Ye SF

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Carotid stenosis is one of the common reasons for patients with ischemic stroke, and the two invasive options carotid endarterectomy (CEA) and carotid artery stenting (CAS) are the most popular treatments. But the relative efficacy and safety of the methods are not clear. METHODS:About 521 articles related ...

journal_title：Chinese medical journal

authors： Wang L,Liu XZ,Liu ZL,Lan FM,Shi WC,Liu J,Zhang JN

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is well known as a hypoxia-induced protein. That it markedly increased expression of VEGF and improvement of rat motor function after spinal cord injury suggested that VEGF could play a neuroprotective role in ischaemic tolerance. This study investigated whether vasc...

journal_title：Chinese medical journal

authors： Ding XM,Mao BY,Jiang S,Li SF,Deng YL

更新日期：2005-10-05 00:00:00

abstract：OBJECTIVE:To determine the distribution of aortic arch and intra/extracranial cerebral arterial atherosclerosis in Chinese patients who had suffered acute ischemic strokes. METHODS:Eighty-nine patients with acute ischemic strokes were included in this study. Transesophageal echocardiography (TEE) was used to evaluate ...

journal_title：Chinese medical journal

authors： Guo Y,Jiang X,Chen S,Zhang S,Zhao H,Wu Y

更新日期：2003-12-01 00:00:00