Effects of prostaglandin E2 and all-trans retinoic acid combination on induced differentiation of human acute promyelocytic leukemia NB4 cells.

abstract：:Induced pluripotent stem (iPS) cells are a recent development which has brought a promise of great therapeutic values. The previous technique of somatic cell nuclear transfer (SCNT) has been ineffective in humans. Recent discoveries show that human fibroblasts can be reprogrammed by a transient over expression of a sm...

journal_title：Chinese medical journal

authors： Bhowmik S,Li Y

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To investigate whether PreS1 antigen and/or anti-PreS1 antibody in serum might have some significance different from routine hepatitis B virus (HBV) markers in hepatitis B virus infection. METHODS:Forty-six acute hepatitis B patients and 377 chronic persistent hepatitis patients were examined to assess the c...

journal_title：Chinese medical journal

authors： Mi Z,Feng F,Zhang X,Lian Z,Wang H,Tong Y

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Although the use of hepatitis B immunoglobulin (HBIG) may lead to a significant reduction in recurrent hepatitis B virus (HBV) infection and improve the survival of patients who have undergone liver transplantation (LT) for hepatitis B-related diseases, the recurrence of the disease still remains at a lower ...

journal_title：Chinese medical journal

authors： Wang WL,Zhang GL,Wu LH,Yao MY,Jin J,Jia CK,Xie HY,Zhou L,Jiang ZJ,Zheng SS

更新日期：2007-09-20 00:00:00

abstract：OBJECTIVE:To evaluate the effects of nitric oxide inhibitor on prostacyclin (PGI2) biosynthesis and the role of PGI2 in hyperhemodynamics of portal hypertension. METHODS:Sprague Dawley rats were divided into four groups: intrahepatic portal hypertension (IHPH) by injection of CCl4, prehepatic portal hypertension (PHPH...

journal_title：Chinese medical journal

authors： Cao H,Wu Z,Zhou J,Chen Z,Kuang Y

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the potential relationship between the dynamic expression of Toll-like receptor 2 and 4 (TLR2/4) in peripheral blood mononuclear cells as well as changes in serum concentration of inflammatory factors and acute lung injury (ALI) in patients after orthotopic liver tran...

journal_title：Chinese medical journal

authors： Chi XJ,Cai J,Luo CF,Cheng N,Hei ZQ,Li SR,Luo GJ

更新日期：2009-04-20 00:00:00

abstract：OBJECTIVE:To evaluate the clinical value of sequential subtraction scintigraphy (SSS) with 99mTc red blood cell (RBC) for the early detection of gastrointestinal (GI) bleeding. METHODS:Ninety patients referred with clinical evidence of GI bleeding underwent 99mTc-RBC scintigraphy with digital gamma camera after labeli...

journal_title：Chinese medical journal

authors： Wu Y,Seto H

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Although some studies have reported that aquaporin-4 (AQP4) plays a role in the post-ischemic edema formation and diffusion-weighted imaging (DWI), little is known about the AQP4 expression in stage of the reperfusion following acute cerebral ischemia, as well as the correlation between histopathology and DW...

journal_title：Chinese medical journal

authors： Lu H,Hu H,He ZP

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of gypenosides (Gs) on cellular immunocompetence in the gamma-ray-irradiated mice. MATERIALS AND METHODS:Tested mice of ICR strain were treated continuously with Gs for 10 days before or after 4 Gy gamma-irradiation. Body weight and splenic weight of mice were measured. The blastog...

journal_title：Chinese medical journal

authors： Hau DM,Feng Y,Chen WC,Lin IH,Chen KT,Lin SS,Wang MI

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Because no data regarding the comparison of crush stenting with paclitaxel (PES) or sirolimus eluting stents (SES) for coronary bifurcate lesions have been reported, we compared the clinical outcomes of these two types of stents. METHODS:Two hundred and thirty patients with 242 bifurcate lesions were enroll...

journal_title：Chinese medical journal

authors： Chen SL,Zhang JJ,Ye F,Chen YD,Zhu ZS,Lin S,Tian NL,Liu ZZ,Fang WY,Sun XW,Hu DY,Kwan TW

更新日期：2008-03-20 00:00:00

abstract：:It is difficult to make a precise diagnosis of intestinal tuberculosis and to differentiate it from Crohn's disease. For evaluating Polymerase Chain Reaction (PCR) assay in these two aspects, 36 specimens of intestinal tuberculosis from surgical resections and endoscopic biopsies and 26 Crohn's disease samples were su...

journal_title：Chinese medical journal

authors： Gan H,Ouyang Q,Bu H,Li S,Chen D,Li G,Yang X

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Nucleostemin is essential for the proliferation and survival of stem and cancer cells, but it is unknown whether this newly identified molecule is involved in prostate cancer pathogenesis. METHODS:Total RNA and protein were extracted from prostate cancer tissues and PC-3, LNCap and DU145 cell lines. The nuc...

journal_title：Chinese medical journal

authors： Liu RL,Zhang ZH,Zhao WM,Wang M,Qi SY,Li J,Zhang Y,Li SZ,Xu Y

更新日期：2008-02-20 00:00:00

abstract：:This paper reports the study of the effect of ginsenopolypeptide on 3H-TdR integration in normal human blood lymphocytes in vitro with micro-blood culture method of 3H-TdR integration. The results showed that the effect of ginsenopolypeptide on 3H-TdR integration in normal human peripheral blood lymphocytes which can ...

journal_title：Chinese medical journal

authors： Wu S,Hua ZJ,Xiao YL,Wang Y,Zhang J,Zhang HY,Du WY

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Sunitinib has been proved an effective new option for treatment of metastatic renal cell carcinoma (mRCC). Analysis of clinical data of 22 patients, who were exposed to sunitinib for at least 1 year, was conducted to evaluate the long-term efficacy and safety of sunitinib for the treatment of mRCC. METHODS:...

journal_title：Chinese medical journal

authors： Zhang CJ,Zhao PJ,Li XS,Zhao J,Huang LH,Song Y,Gong K,Shen C,Yu W,Song G,Zhao Z,Zhang Z,Zhang Q,He ZS,Jin J,Zhou LQ

更新日期：2013-01-01 00:00:00

abstract：:The effect of exercise on pulmonary gas exchange, arterial oxygenation, oxygen transport and delivery, and hemodynamics are studied in 100 patients with chronic obstructive pulmonary diseases. According to the change of PaO2 or PaCO2 induced by exercise, patients were divided into two groups. Group A (n = 52) had sign...

journal_title：Chinese medical journal

authors： Zeng GB,Zhang ZX,Xu YJ,Duan SF

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:A free running asthma screening test is usually used for screening exercise-induced bronchoconstriction. The total serum allergen IgE level can reveal the patient's atopy characteristics. Our study is to evaluate the diagnostic values of the combination of the two tests in asthmatic children and compare this...

journal_title：Chinese medical journal

authors： Chen X,Li Y,Zeng M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a growing public health problem with well-established risk factors. Other contributing factors, however, remain to be identified. Systemic inflammation in asthma plays a significant role in the development of other diseases. We therefore initiated a study to assess whether the...

journal_title：Chinese medical journal

authors： Liu DW,Zhen XG,Liang Y,Jing XG,Zhang TS,Zhang GJ,Liu ZS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Anisodamine is widely used in therapy for treating acute glomerulonephritis and diabetic nephropathy because it can improve renal microcirculation. We performed a study to evaluate the preventive effects of anisodamine against contrast-induced nephropathy (CIN) in type 2 diabetics with renal insufficiency un...

journal_title：Chinese medical journal

authors： Geng W,Fu XH,Gu XS,Wang YB,Wang XC,Li W,Jiang YF,Hao GZ,Fan WZ,Xue L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a Th2 dominant cytokine response. Chloride channel-3 (ClC-3) plays an important role in nasal mucosal edema and inflammatory pathologic changes in AR. Antiallergic herbal agents (AHA) are antiallergic herbal products. In the previous study, we have demonstrated that AHA clearly inhi...

journal_title：Chinese medical journal

authors： Wang LF,Xu LJ,Guo FH,Wang LN,Shen XH

更新日期：2010-04-20 00:00:00

abstract：OBJECTIVE:To compare the effect of ouabain on the blood pressure of rats with that of digoxin to find the evidences of the relationship between endogenous ouabain (EO) and development of hypertension. METHODS:Sprague-Dawley rats, which were divided into 3 groups, were infused with ouabain (23 x 75 micrograms.kg-1/day,...

journal_title：Chinese medical journal

authors： Wang H,Lu Z,Yuan W

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A (SAA) levels and the incidence of atherosclerosis (AS) in patients with short-duration type 2 diabetes mellitus (T2DM) without macroangiopathy, and whether intensive multif...

journal_title：Chinese medical journal

authors： Du JL,Liu JF,Men LL,Yao JJ,Sun LP,Sun GH,Song GR,Yang Y,Bai R,Xing Q,Li CC,Sun CK

更新日期：2009-11-05 00:00:00

abstract：OBJECTIVE:To describe the methods which were used to develop collagen-based materials for wound dressing. METHODS:Fresh frozen bovine tendon was treated with 0.05 mol/L acetic acid at pH 3.2 for 48-72 hours, homogenized, filtered, mixed with 8% chondroitin sulphate, for creating a deaerated 1.5%-2.5% collagen solution...

journal_title：Chinese medical journal

authors： Wu Z,Sheng Z,Sun T,Geng M,Li J,Yao Y,Huang Z

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomida...

journal_title：Chinese medical journal

authors： Tan HY,Sun LN,Wang XL,Ye TH

更新日期：2010-03-20 00:00:00

abstract：BACKGROUND:This prospective, randomized, controlled study was designed to investigate the effects of a diabetes specific formula (Diason low energy: 313.8 kJ/100 ml), compared with a standard formula, on insulin sensitivity, serum C peptide, serum lipids and free fatty acid (FFA) in type 2 diabetics. METHODS:In total ...

journal_title：Chinese medical journal

authors： Li YX,Zeng JB,Yu K,Sun Q,Liu QY,Qin W,Zhang Q,Yu JC,Wang H

更新日期：2008-04-20 00:00:00

abstract：OBJECTIVE:To explore a new method for the therapy of avascular necrosis of the femoral head. METHODS:The recombinant plasmid pCD-hVEGF165 was mixed with collagen and was implanted in the necrotic femoral head. The expression of vascular endothelial growth factor (VEGF) was examined by RNA dot hybridization and immunoh...

journal_title：Chinese medical journal

authors： Yang C,Yang S,Du J,Li J,Xu W,Xiong Y

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) is a serious and common condition for which there are currently no specific strategies for treatment. Recent studies have suggested that bone marrow-derived multipotent mesenchymal stem cells (MSCs) may have therapeutic applications in multiple clinical disorders. We explored the biol...

journal_title：Chinese medical journal

authors： Liang ZX,Sun JP,Wang P,Tian Q,Yang Z,Chen LA

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To discuss the diagnosis and surgical treatment of temporal lobe epilepsy. METHODS:From 1996 to 1998, 36 patients presenting with medically intractable temporal lobe epilepsy were identified by EEG and MR, including volumetric MR, for hippocampal formation. Among them, 16 patients underwent anterior temporal...

journal_title：Chinese medical journal

authors： Gao X,Jiang C,Shi Y

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Drug treatment for secondary hyperparathyroidism caused by chronic renal failure may be available at the early stage of the disease, but it is not as effective for serious patients. The aim of the study was to evaluate the effect of total parathyroidectomy combined with forearm autotransplantation in the ure...

journal_title：Chinese medical journal

authors： Zou Q,Wang HY,Zhou J,Lao ZY,Xue J,Li MX,Li HM,Jin YT,Gu Y,Zhang YL

更新日期：2007-10-20 00:00:00

abstract：OBJECTIVE:To determine mutations of two common potassium channel subunit genes KCNQ1, KCNH2 causing long QT syndrome (LQTS) in the Chinese. METHODS:Thirty-one Chinese LQTS pedigrees were characterized for mutations in the two LQTS genes, KCNQ1 and KCNH2, by sequencing. RESULTS:Two novel KCNQ1 mutations, S277L in the ...

journal_title：Chinese medical journal

authors： Liu W,Hu D,Li C,Li P,Li Y,Li Z,Li L,Qin X,Dong W,Qi Y,Chen S,Wang Q

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Chronic graft-versus-host disease (GVHD), the commonest long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT), has a negative impact on patients' health related quality of life (HRQoL). This study was designed to investigate the HRQoL in patients with chronic GVHD in China. ...

journal_title：Chinese medical journal

authors： Mo XD,Xu LP,Liu DH,Chen YH,Zhang XH,Chen H,Han W,Wang Y,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The acetabular teardrop is often used to guide acetabular component placement in total hip arthroplasty (THA). Placing the lower acetabular component aspect at the same level as the lower teardrop edge was assumed to restore the hip center of rotation. Here we radiographically analyzed the relationship betwe...

journal_title：Chinese medical journal

authors： Lu Y,Cheng L,Guo W,Yu Q,Gao F,Zhang Q,Liu Z,Sun W,Shi Z

更新日期：2014-01-01 00:00:00