Induced pluripotent stem cells.

abstract：OBJECTIVE:To evaluate the effect of gynostemma pentaphyllum mak (GP) on carcinomatous conversions of leukoplasia of the golden hamster cheek pouch induced by dimethylbenzanthracene (DMBA). METHODS:284 golden hamsters, ranging from 4 to 8 weeks of age, 80 to 100 grams in weight were randomly divided into three groups: ...

journal_title：Chinese medical journal

authors： Zhou Z,Wang Y,Zhou Y,Zhang S

更新日期：1998-09-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained dysrhythmia in clinical practice. The bulk of evidence suggests that inflammatory processes, oxidative stress and matrix metalloproteinase are associated with development of AF. However, these agents may be involved in high mobility group box 1 protein (HMGB1). We ...

journal_title：Chinese medical journal

authors： Hu XR,Wang XH,Liu HF,Zhou WJ,Jiang H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Optical coherence tomography (OCT) is a high resolution noncontact imaging modality which can quantitatively detect the optic disc and retinal structure. This study was designed to evaluate the diagnostic capability of parameters of the optic disc, retinal nerve fiber layer thickness, and ganglion cell compl...

journal_title：Chinese medical journal

authors： Fang Y,Pan YZ,Li M,Qiao RH,Cai Y

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:The In1.1C single nucleotide polymorphism (SNP) allele results in reduced RANTES transcription, which is associated with increased frequency of HIV-1 infection, and rapid progression to AIDS among HIV-1-infected individuals. This study aimed to study the mutant frequency and polymorphism of RANTES in Chinese...

journal_title：Chinese medical journal

authors： Qian Y,Sun H,Chu JY

更新日期：2009-05-20 00:00:00

abstract：BACKGROUND:The columella, nasal tip, lip relationship in the bilateral cleft lip nasal deformity remains a great challenge for plastic surgeon. An esthetically satisfying result is difficult to obtain. A subset of patients with bilateral cleft lip nasal deformity still require columellar lengthening and nasal correctio...

journal_title：Chinese medical journal

authors： Yan W,Zhao ZM,Yin NB,Song T,Li HD,Wu D,Gao F,Wang XG

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Apoptosis is a major cause of ischemic heart dysfunction. Apelin, the endogenous ligand for the G-protein-coupled APJ receptor, has been reported to exert cardioprotective effects during myocardial injury. The aim of this study was to investigate the effects of apelin on apoptosis of rat cardiomyocytes induc...

journal_title：Chinese medical journal

authors： Zhang Z,Yu B,Tao GZ

更新日期：2009-10-05 00:00:00

abstract：:The effects of mebendazole (Meb), albendazole (Alb) and albendazole sulfoxide (AlbSO) on metacestodes of Echinococcus granulosus have been studied. The results show that Meb and Alb exhibit less effect on protoscoleces in vitro, but in vivo the protoscolicidal effect of Meb is higher than that of Alb. Both Meb and Alb...

journal_title：Chinese medical journal

authors： Xiao SH,Yang YQ,You JQ,Shen BG,Jiao W,Chai JJ

更新日期：1994-07-01 00:00:00

abstract：:This paper reports the study of the effect of ginsenopolypeptide on 3H-TdR integration in normal human blood lymphocytes in vitro with micro-blood culture method of 3H-TdR integration. The results showed that the effect of ginsenopolypeptide on 3H-TdR integration in normal human peripheral blood lymphocytes which can ...

journal_title：Chinese medical journal

authors： Wu S,Hua ZJ,Xiao YL,Wang Y,Zhang J,Zhang HY,Du WY

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND:Laparoscopic Heller cardiomyotomy and Dor fundoplication is the surgical procedure of choice for esophageal achalasia. The aim of this study was to investigate the clinical outcome of laparoscopic Heller-Dor procedure in our initial series of 25 patients with achalasia. METHODS:Between October 2003 and Janu...

journal_title：Chinese medical journal

authors： Wang QS,Liu L,Dong L,Shen ZL,Zhou DH,Hu CX

更新日期：2006-03-20 00:00:00

abstract：BACKGROUND:CD4(+)CD25(+) regulatory T cells (Tregs) mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), and transforming growth factor beta (TG...

journal_title：Chinese medical journal

authors： Zhang Q,Qian FH,Liu H,Zhou LF,Huang M,Zhang XL,Yin KS

更新日期：2008-02-05 00:00:00

abstract：BACKGROUND:Novel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A (H10N8) virus which can infect humans and cause severe diseases. METHODS:Collecting clinical data of three cases of human infection with a novel reas...

journal_title：Chinese medical journal

authors： Zhang W,Wan J,Qian K,Liu X,Xiao Z,Sun J,Zeng Z,Wang Q,Zhang J,Jiang G,Nie C,Jiang R,Ding C,Li R,Horby P,Gao Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Some individuals have multiple renal arteries. Severe stenosis in one of the arteries may cause refractory hypertension. The detection of stenosis within one of the multiple renal arteries usually required invasive procedures, such as computed tomographic angiography (CTA) and magnetic resonance angiography ...

journal_title：Chinese medical journal

authors： Qin W,Zhang X,Yang M,Zhong XH,Zhao MH

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Acinetobacter baumanii (A. baumanii ) remains an important microbial pathogen resulting in nosocomial acquired infections with significant morbidity and mortality. The mechanism by which nosocomial bacteria, like A. baumanii, attain multidrug resistance to antibiotics is of considerable interest. The aim in ...

journal_title：Chinese medical journal

authors： Dai N,Li DZ,Chen JC,Chen YS,Geng R,Hu YH,Yang JP,DU J,Hu CP,Zhang W,Li JS,Yu Q,Wan HY,Mu L,Zhong XN,Wei LP,Ma JJ,Wang QY,Hu K,Tian GZ,Cai SX,Wang RQ,He B,Wang SQ,Wang ZW,Zhao SR,Gao ZC

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Over 70% of the total tissue weight in the cartilage matrix consists of water, and the early-stage osteoarthritic cartilage is characterized by swelling. Water transport in the cartilage matrix and across the membranes of chondrocytes may be important in normal and pathological conditions of cartilage. The p...

journal_title：Chinese medical journal

authors： Meng JH,Ma XC,Li ZM,Wu DC

更新日期：2007-12-20 00:00:00

abstract：:A 30-year-old female patient with coexisting ankylosing spondylitis and rheumatoid arthritis was diagnosed and treated. The human leukocyte antigen (HLA)-B27 is a predisposing factor of ankylosing spondylitis and HLA-DR4 is a predisposing factor of rheumatoid arthritis. This patient was HLA-B27 and HLA-DR4 positive, a...

journal_title：Chinese medical journal

authors： Guo YY,Yang LL,Cui HD,Zhao S,Zhang N

更新日期：2011-10-01 00:00:00

abstract：Background:Endometriosis is a challenging disease with symptoms such as dysmenorrhea and infertility. However, its etiology is still vague and there is still no effective markers or treatment. This study aimed to profile the circular RNAs (circRNAs) expressed in eutopic endometrium from patients with ovarian endometrio...

journal_title：Chinese medical journal

authors： Xu XX,Jia SZ,Dai Y,Zhang JJ,Li XY,Shi JH,Leng JH,Lang JH

更新日期：2018-03-05 00:00:00

abstract：OBJECTIVE:To investigate an method for hepatic differentiation from embryonic stem cells (ES cells) in vitro and the resulting differentiation ratio, in order to develop a procedure for producing a new type of hepatocyte for hepatocyte replacement therapy in the treatment of liver failure. METHODS:ES cells from Balb/C...

journal_title：Chinese medical journal

authors： Hu A,Cai J,Zheng Q,He X,Pan Y,Li L

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility, safety and diagnostic accuracy of pharmacologic stress of (99m)Technetium-MIBI single-photon emission computed tomography (SPECT) with intravenous adenosine triphosphate (ATP) in patients with suspected coronary artery disease. METHODS:The study group included 263 patients who we...

journal_title：Chinese medical journal

authors： He Q,Yao Z,Yu X,Qu W,Sun F,Ji F,Xu F,Qian Y

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:It was well known that tangential vitreoretinal traction and epiretinal membrane play important roles during the formation of macular hole (MH) associated with retinal detachment (RD) in highly myopic eyes. But it was not clear about the correlations between anteroposterior traction, posterior vitreous corte...

journal_title：Chinese medical journal

authors： Liu HY,Zou HD,Liu K,Song ZY,Xu X,Sun XD

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:In vivo quantification of choroidal neovascularization (CNV) based on noninvasive optical coherence tomography (OCT) examination and in vitro choroidal flatmount immunohistochemistry stained of CNV currently were used to evaluate the process and severity of age-related macular degeneration (AMD) both in huma...

journal_title：Chinese medical journal

authors： Nie C,Zhang MN,Zhao HW,Olsen TD,Jackman K,Hu LN,Ma WP,Chen XF,Wang J,Zhang Y,Gao TS,Uehara H,Ambati BK,Luo L

更新日期：2015-06-05 00:00:00

abstract：BACKGROUND:A correct thyroid function reference range is important for the accurate diagnosis of thyroid disease during pregnancy. However, there is no consensus on whether thyroid function reference ranges in Chinese population should follow the America Thyroid Association (ATA) guidelines. This study aimed to establi...

journal_title：Chinese medical journal

authors： Yang X,Meng Y,Zhang Y,Zhang C,Guo F,Yang S,Ding R,Fan JX

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:As a new electroencephalogram (EEG) signal processing technique for monitoring the depth of anesthesia, entropy consists of two indices: reaction entropy (RE) and state entropy (SE). Our study compared entropy with classical bispectral index (BIS) in reduction of myoelectrical interference and noxious stimul...

journal_title：Chinese medical journal

authors： Gao JD,Zhao YJ,Xu CS,Zhao J,Huang YG,Wang TL,Pei L,Wang J,Yao LN,Ding Q,Tan ZM,Zhu ZR,Yue Y

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the roles of folic acid and beta-carotene in the chemoprevention of gastric and other gastrointestinal (GI) cancers. METHODS:In a randomized, double-blind, placebo-controlled trial, a total of 216 patients with atrophic gastritis were randomly assigned to one of the four groups: (1) folate (FA, 2...

journal_title：Chinese medical journal

authors： Zhu S,Mason J,Shi Y,Hu Y,Li R,Wahg M,Zhou Y,Jin G,Xie Y,Wu G,Xia D,Qian Z,Sohg H,Zhang L,Russell R,Xiao S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Eating disorders (EDs) are serious illnesses associated with medical complications and have been increased, especially among societies with an excessive concern about weight, shape, or appearance. This study aimed to investigate the prevalence of EDs among the individuals attending weight management centers ...

journal_title：Chinese medical journal

authors： Eladawi N,Helal R,Niazy NA,Abdelsalam S

更新日期：2018-01-05 00:00:00

abstract：BACKGROUND:Glucocorticoid is speculated to be able to have Aspergillus fumigatus (A. fumigatus) being more susceptible to reactive oxygen species (ROS) by inhibiting Afyap1, the transcription factor activating protein-1 (AP-1) homologue in A. fumigatus, which may provide a clue to expand the clinical use of glucocortic...

journal_title：Chinese medical journal

authors： Xu H,Li LJ,Wan Z,Li RY,Liu W

更新日期：2011-11-01 00:00:00

abstract：:131 cases of epidemic hepatitis from two villages in Xinjiang, were admitted to the provisional infectious diseases hospital from February to April 1987. In 125 (95%) patients neither anti-HAV IgM nor anti-HBc IgM were positive. 118 (90%) were drinking water from a local stream of the Hotan River. The study was conduc...

journal_title：Chinese medical journal

authors： Wang XC,Liu XM,Tan CZ,Liu R,Luo SL,Yue XH,Qin F,Bu ZR,Tian X,Song DY

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Long-term use of benzalkonium chloride (BAC)-preserved drugs is often associated with ocular surface toxicity. Ocular surface symptoms had a substantial impact on the glaucoma patients' quality of life and compliance. This study aimed to investigate the effects of sodium hyaluronate (SH) on ocular surface to...

journal_title：Chinese medical journal

authors： Liu X,Yu FF,Zhong YM,Guo XX,Mao Z

更新日期：2015-09-20 00:00:00

abstract：OBJECTIVE:To report the surgical techniques and results of an 8-year follow-up study of 42 patients with a modified orthotopic ileal neobladder restoring normal anatomical relationship. METHODS:Total cystoprostatectomy was performed extraperitoneally. A 45 - 50 cm segment of the ileal loop was isolated, detubularized,...

journal_title：Chinese medical journal

authors： Huang J,Xu K,Yao Y,Guo Z,Lin T,Jiang C

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Hemolysis-elevated liver enzymes-low platelet counts (HELLP) syndrome is a clinical condition occurring in middle and late stage pregnancy. It is characterized by hemolysis, elevated liver enzymes and low platelet counts. This study involves the analysis of the diagnosis, clinical characteristics and treatme...

journal_title：Chinese medical journal

authors： Wang YQ,Wang J,Ye RH,Zhao YY

更新日期：2010-05-20 00:00:00