Big Data Research in Chronic Kidney Disease.

abstract：BACKGROUND:Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). However, only 10% - 20% of chronic heavy cigarette smokers develop symptomatic disease. COPD is most likely the result of complex interactions between environmental and genetic factors. Genetic susceptibility to COPD...

journal_title：Chinese medical journal

authors： Xiao D,Wang C,Du MJ,Pang BS,Zhang HY,Xiao B,Liu JZ,Weng XZ,Su L,Christiani DC

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Previous studies have showed that photooxidative stress can lead to down-modulation of nuclear factor-kappa B (NF-kappaB) activity causing apoptosis of cultured photoreceptor cells. This study aimed at investigating whether NF-kappaB was involved in photoreceptor cells apoptosis induced by N-methyl-N-nitroso...

journal_title：Chinese medical journal

authors： Yang JN,Luo L,Lin SC,Chen JM,Li D,Hu SX

更新日期：2005-07-05 00:00:00

abstract：OBJECTIVE:To study the ultrastructural damages of brain tissues dynamically after middle cerebral artery obstruction (MCAO). METHODS:A middle cerebral artery obstruction (MCAO) model was reproduced in renal vascular hypertensive rats (RHR). Brain tissues in different locations were collected for eight times in row, fr...

journal_title：Chinese medical journal

authors： Fang Y,Huang R,Su Z,Lin J,Li J

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Image-guided radiation therapy (IGRT) is the preferred method for curative treatment of localized prostate cancer, which could improve disease outcome and reduce normal tissue toxicity reaction. IGRT using cone-beam computed tomography (CBCT) in combination with volumetric-modulated arc therapy (VMAT) potent...

journal_title：Chinese medical journal

authors： Li M,Li GF,Hou XY,Gao H,Xu YG,Zhao T

更新日期：2016-06-20 00:00:00

abstract：BACKGROUND:Early neurological deterioration (END) is a prominent issue after recanalization treatment. However, few studies have reported the characteristics of END after endovascular treatment (EVT) as so far. This study investigated the incidence, composition, and outcomes of END after intravenous recombinant tissue ...

journal_title：Chinese medical journal

authors： Zhang YB,Su YY,He YB,Liu YF,Liu G,Fan LL

更新日期：2018-01-20 00:00:00

abstract：BACKGROUND:Fractional flow reserve (FFR) has become an increasingly important index when making decisions with respect to revascularization of coronary artery stenosis. However, the pressure guidewire used in obtaining FFR measurements is difficult to control and manipulate in certain complex coronary artery lesions, r...

journal_title：Chinese medical journal

authors： He WM,Li CL,Sun Y,Zhou Z,Mai YF

更新日期：2015-03-20 00:00:00

abstract：OBJECTIVE:To investigate the correlation among retinal fluorescein angiography, blood viscosity, and other factors in patients with open angle glaucoma (POAG). METHODS:Multiple step regression analysis was made to investigate the correlation between each of the following blood vessel filling times: the arm-choroid (A-...

journal_title：Chinese medical journal

authors： Liu X,Zhou W,Ye T,Ge J,Cai X,Cheng A,Lin Y,Liang L,Tang H,Chen Z

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Sericin peptide (SP) has shown a powerful anti-oxidant property in a host of studies. The present study was designed to investigate the possible protective effects of SP against alcohol-induced gastric lesions in mice and to explore the potential mechanisms. METHODS:Animals were randomly divided into 5 grou...

journal_title：Chinese medical journal

authors： Li YG,Ji DF,Lin TB,Zhong S,Hu GY,Chen S

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Up to now there have been no satisfactory drugs to treat psychiatric disorders, and now bioactive compound from entomagenous fungi (BCEF0083) is a new type of bioactive compound from entomopathogenic fungi. Our previous investigations have shown that BCEF has an inhibition effect on monoamine oxidase. So, BC...

journal_title：Chinese medical journal

authors： Zhou LL,Ming L,Ma CG,Cheng Y,Jiang Q

更新日期：2005-06-05 00:00:00

abstract：BACKGROUND:We conducted a prospective, multicenter investigation of incidence, management and outcome of neonatal acute respiratory disorders (NARD), and evaluated related perinatal risk factors and efficacy of respiratory therapies in neonatal intensive care units (NICUs) in a Chinese neonatal network. METHODS:Data w...

journal_title：Chinese medical journal

authors： Qian LL,Liu CQ,Guo YX,Jiang YJ,Ni LM,Xia SW,Liu XH,Zhuang WZ,Xiao ZH,Wang SN,Zhou XY,Sun B,Chinese Collaborative Study Group for Neonatal Respiratory Diseases.

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Pancreatic beta-cell apoptosis induced by lipotoxicity, to a large extent, contributes to the progression of type 2 diabetes. To investigate the mechanism of free fatty acid induced apoptosis, we aimed to study the effects of palmitic acid (PA) on the apoptosis and peroxisome proliferator-activated receptor ...

journal_title：Chinese medical journal

authors： He TT,Cao XP,Chen RZ,Zhu XN,Wang XL,Li YB,Xiao HP

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Dynesys dynamic stabilization system was first implanted in patients in 1994, and introduced to China in 2007. Therefore, it was a new technique for Chinese orthopedics and hence necessary to collect clinical data about Dynesys in China. The objective of this study was to report the preliminary results of Dy...

journal_title：Chinese medical journal

authors： Li HP,Li F,Guan K,Zhao GM,Shan JL,Sun TS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Precise evaluation of the live donor's liver is the most important factor for the donor's safety and the recipient's prognosis in living donor liver transplantation (LDLT). Our study assessed the clinical value of computer-assisted three-dimensional quantitative assessment and a surgical planning tool for do...

journal_title：Chinese medical journal

authors： Wei L,Zhu ZJ,Lü Y,Jiang WT,Gao W,Zeng ZG,Shen ZY

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of preoperative transcatheter arterial chemoembolization(TACE) on apoptosis of hepatocellular carcinoma (HCC) cells. METHODS:A total of 136 patients with HCC underwent liver resection. One to five courses of TACE prior to liver resection were performed in 79 patients (TACE group), in w...

journal_title：Chinese medical journal

authors： Xiao E,Li D,Shen S,Zhou S,Tan L,Wang Y,Luo J,Wu Y,Tan C,Liu H,Zhu H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Hippophae rhamnoides L. (HL) exerts antioxidant activities against various oxidative stress conditions. In this study, we investigated effects of extract from HL leaves (HLE) on cell proliferation and neuroblast differentiation in the subgranular zone (SGZ) of the dentate gyrus (DG) of aged gerbils. METHODS...

journal_title：Chinese medical journal

authors： Ahn JH,Chen BH,Park JH,Kim IH,Cho JH,Lee JC,Yan BC,Choi JH,Hwang IK,Park JH,Han SN,Lee YL,Kim MJ,Won MH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The incidence of vancomycin-resistant enterococci (VRE) appeared to be increasing in China, but very few nosocomial outbreaks have been reported. Our hospital had experienced an outbreak of VRE since March 2008 to March 2009. The objective of this study was to analyze the molecular features of the isolates a...

journal_title：Chinese medical journal

authors： Xu HT,Tian R,Chen DK,Xiao F,Nie ZY,Hu YJ,Zhang XZ,Li JM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Enhanced recovery after surgery (ERAS) protocols are a series of perioperative care to optimize preoperative preparation, prevent postoperative complications, minimize stress, and speed up recovery. This study aimed to assess the impact of ERAS protocols for functional endoscopic sinus surgery (FESS) in pati...

journal_title：Chinese medical journal

authors： Wu XF,Kong WF,Wang WH,Yuan LX,Xu HQ,Qi M,Zhou SL,Yang QT

更新日期：2019-02-05 00:00:00

abstract：OBJECTIVE:To provide appropriate guidelines for treatment of tandem ossification of the posterior longitudinal ligament (OPLL) and flaval ligament (OFL). Data sources Published articles about OPLL and OFL were selected using Medline and Embase electronic databases. Study selection An English literature search from Janu...

journal_title：Chinese medical journal

authors： Guo JJ,Yang HL,Cheung KM,Tang TS,Luk KD

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:Both repaglinide and gliclazide are insulin secretagogues widely used in the treatment of type 2 diabetes. They stimulate insulin secretion through distinct mechanisms and may benefit patients from different aspects. The present study was to evaluate the effects of repaglinide or gliclazide on glycaemic cont...

journal_title：Chinese medical journal

authors： Zhang H,Bu P,Xie YH,Luo J,Lei MX,Mo ZH,Liao EY

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:A simple, safe and effective therapeutic strategy for traumatic instability of the subaxial cervical spine, as well as its prognostic assessment, is still controversial. METHODS:The therapeutic options for 83 patients of traumatic instability of the subaxial cervical spine, whose average age was 35 years, w...

journal_title：Chinese medical journal

authors： Cao P,Liang Y,Gong YC,Zheng T,Zhang XK,Wu WJ

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:The activation of extracellular signal-regulated kinase1/2 (ERK1/2) has been shown to be important signaling pathway in the ischemic preconditioning (IPC) response. Recently, some studies suggest a key role for the mitochondrial ATP-sensitive potassium channel (mKATP) as both a trigger and an end effector of...

journal_title：Chinese medical journal

authors： Gong KZ,Zhang ZG,Li AH,Huang YF,Bu P,Dong F,Liu J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Postoperative preablative stimulated thyroglobulin (ps-Tg) has been evaluated in predicting prognosis and success of ablation regarding differentiated thyroid cancer (DTC); however, its relationship with recurrence risk and radioiodine decision-making remains uncertain, especially in Chinese DTC patients. We...

journal_title：Chinese medical journal

authors： Yang X,Liang J,Li TJ,Yang K,Liang DQ,Yu Z,Lin YS

更新日期：2015-04-20 00:00:00

abstract：BACKGROUND:Aquired immune deficiency syndrome (AIDS) presents a challenge to medical researchers because of its unique pathological and clinical picture. The clinical data, particularly autopsy evidence, from China have failed to provide enough pathological and etiological evidence for AIDS diagnosis, which impairs the...

journal_title：Chinese medical journal

authors： Li HJ,Gao YQ,Cheng JL,Zhang YZ

更新日期：2009-09-20 00:00:00

abstract：BACKGROUND:In many studies, obstructive sleep apnea (OSA) has been shown to be an independent risk factor for cardiovascular disease. Conversely, there are few reports establishing possible relation between OSA and venous thromboembolism (VTE). In this study, the aim is to evaluate OSA via polysomnography in patients w...

journal_title：Chinese medical journal

authors： Kezban OS,Ali NA,Umran T,Talha D,Ege GB,Peri A,Leyla YA,Hasan S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The side effects of cyclosporine therapy include thromboembolic complications. However, the mechanisms underlying the hypercoagulable state induced by cyclosporine are not fully understood. Cyclosporine binds to red blood cells (RBCs) with a high affinity in circulation and alters the membranes of RBCs. Ther...

journal_title：Chinese medical journal

authors： Zheng YN,Yu HJ,Hou JX,Lu CF,Zhou J

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Anisodamine is widely used in therapy for treating acute glomerulonephritis and diabetic nephropathy because it can improve renal microcirculation. We performed a study to evaluate the preventive effects of anisodamine against contrast-induced nephropathy (CIN) in type 2 diabetics with renal insufficiency un...

journal_title：Chinese medical journal

authors： Geng W,Fu XH,Gu XS,Wang YB,Wang XC,Li W,Jiang YF,Hao GZ,Fan WZ,Xue L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Visfatin, a visceral fat-derived adipocytokine, plays a significant physiological function in lipid metabolism. However, the precise function of visfatin and its regulation by thyroid hormones are still unknown. This study observed the plasma visfatin concentrations in subjects with hyperthyroidism and hypot...

journal_title：Chinese medical journal

authors： Han J,Zhang TO,Xiao WH,Chang CQ,Ai H

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Intravascular ultrasound (IVUS) examination can provide useful information during endovascular stent graft repair. However, its actual clinical utility in thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (type B-AD) remains unclear, especially in complicated aortic dissection. We eval...

journal_title：Chinese medical journal

authors： Guo BL,Shi ZY,Guo DQ,Wang LX,Tang X,Li WM,Fu WG

更新日期：2015-09-05 00:00:00

abstract：OBJECTIVE:To describe the methods which were used to develop collagen-based materials for wound dressing. METHODS:Fresh frozen bovine tendon was treated with 0.05 mol/L acetic acid at pH 3.2 for 48-72 hours, homogenized, filtered, mixed with 8% chondroitin sulphate, for creating a deaerated 1.5%-2.5% collagen solution...

journal_title：Chinese medical journal

authors： Wu Z,Sheng Z,Sun T,Geng M,Li J,Yao Y,Huang Z

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Antiphospholipid syndrome (APS)-related immune factors are considered as an important cause of recurrent spontaneous abortion (RSA). Anticoagulant and anti-inflammatory treatments are believed to effectively improve adverse pregnancy outcomes by affecting the abnormal autoimmune response of the maternal-feta...

journal_title：Chinese medical journal

authors： Ye SL,Gu XK,Tao LY,Cong JM,Wang YQ

更新日期：2017-06-20 00:00:00