N-methyl-N-nitrosourea-induced apoptosis of photoreceptor cells in Sprague-Dawley rats via nuclear factor-kappaB.

abstract：BACKGROUND:Gastric cancer (GC) is one of the most globally prevalent cancers in the world. The pathogenesis of GC has not been fully elucidated, and there still lacks effective targeted therapeutics. The influence of altered kinesin superfamily protein 22 (KIF22) expression in GC progression is still unclearly. The aim...

journal_title：Chinese medical journal

authors： Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

更新日期：2020-04-20 00:00:00

abstract：:Patients whose routine MRI were negative but were clinically highly suspected of having intra-cranial or intra-spinal canal space-occupying lesions, and those whose routine MRI were positive but presented difficulties in defining the contour or the nature of the lesion, or difficulty in distinguishing the lesion from ...

journal_title：Chinese medical journal

authors： Shen TZ,Mei H,Huang XL,Chen XR

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients. METHODS:The study subjects were 49 cancer patients (1.4%) out of 3448 end stage renal disease...

journal_title：Chinese medical journal

authors： Zhou L,Cao YL,Li WG,Fu FT,Zhang L,Wang X,Shi XH

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Gastric intestinal metaplasia (GIM) is generally considered to be the main mucosal background for the development of gastric adenocarcinomas. Using linked color imaging (LCI), we noticed that the color pattern in areas of GIM was purple mixed with white on the epithelium with signs of mist that were detected...

journal_title：Chinese medical journal

authors： Min M,Dong TH,Liu Y,Bi YL,Ma CY

更新日期：2019-04-05 00:00:00

abstract：OBJECTIVE:To evaluate the effect of preoperative transcatheter arterial chemoembolization(TACE) on apoptosis of hepatocellular carcinoma (HCC) cells. METHODS:A total of 136 patients with HCC underwent liver resection. One to five courses of TACE prior to liver resection were performed in 79 patients (TACE group), in w...

journal_title：Chinese medical journal

authors： Xiao E,Li D,Shen S,Zhou S,Tan L,Wang Y,Luo J,Wu Y,Tan C,Liu H,Zhu H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Mutation or deletion in the phosphatase and tensin homologue deleted on chromosome ten (PTEN) gene has been identified as an important cause of endometrial carcinoma; stromal cell derived factor-1alpha (SDF-1alpha) exerts growth-promoting effects on endometrial cancer cells through activation of the PI-3 kin...

journal_title：Chinese medical journal

authors： Li XP,Zhao D,Gao M,Zhao C,Wang JL,Wei LH

更新日期：2006-03-05 00:00:00

abstract：BACKGROUND:Precise evaluation of the live donor's liver is the most important factor for the donor's safety and the recipient's prognosis in living donor liver transplantation (LDLT). Our study assessed the clinical value of computer-assisted three-dimensional quantitative assessment and a surgical planning tool for do...

journal_title：Chinese medical journal

authors： Wei L,Zhu ZJ,Lü Y,Jiang WT,Gao W,Zeng ZG,Shen ZY

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Tenofovir disoproxil (TDF) is a promising salvage therapy for patients with chronic hepatitis B (CHB) who failed regimens of other nucleoside analogues (NAs). In this study, we aimed to investigate the clinical efficacy and safety of TDF monotherapy in Chinese CHB patients with genotypic resistance. METHODS...

journal_title：Chinese medical journal

authors： Zhou J,Liu YY,Lian JS,Pan LF,Yang JL,Huang JR

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Fractional flow reserve (FFR) has become an increasingly important index when making decisions with respect to revascularization of coronary artery stenosis. However, the pressure guidewire used in obtaining FFR measurements is difficult to control and manipulate in certain complex coronary artery lesions, r...

journal_title：Chinese medical journal

authors： He WM,Li CL,Sun Y,Zhou Z,Mai YF

更新日期：2015-03-20 00:00:00

abstract：BACKGROUND:The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery Score II (SS-II) can well predict 4-year mortality in patients with complex coronary artery disease (CAD), and guide decision-making between coronary artery bypass graft surgery and percutaneous coronary intervention (PCI)....

journal_title：Chinese medical journal

authors： He JQ,Yu XP,Peng C,Li Q,Luo YW,Gao YC,Zhang XL,Wu CY,Zhao H,Zhang YC,Liu JH,Lyu SZ,Chen F

更新日期：2015-08-20 00:00:00

abstract：:In 16 dogs the endothelium of the left anterior descending coronary artery was injured mechanically. Then a copper wire was inserted into the lumen as a choke of flow and the vessel was slightly compressed from outside by a constrictor. Eight dogs had been treated beforehand with a preparation of flavone extracted fro...

journal_title：Chinese medical journal

authors： Zhao HY,Fang WY

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Idiopathic choroidal neovascularization (ICNV) is an uncommon disorder affecting primarily individuals younger than the age of 50 years. In CNV patients, no apparent cause can be determined. This study aimed to evaluate the functional and morphological change of the retina with ICNV in young adults. METHODS...

journal_title：Chinese medical journal

authors： Wang WQ,Liu HY,Lu FQ,Hu WT,Gong YY,Wu Y,Xu S,Wang WJ,Xu X,Wang FH,Sun XD

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Recurrence or metastasis of myxomas is not rare and can lead to malignancy. We aimed to analyze the risk factors for postoperative cardiac myxoma recurrence and to summarize its clinical characteristics, treatments and classification. METHODS:The clinical data of 5 patients with recurrent cardiac myxoma wer...

journal_title：Chinese medical journal

authors： Sheng WB,Luo BE,Liu Y,Zhang H,Zou LJ,Xu ZY,Zhang HY,Ji GY

更新日期：2012-08-01 00:00:00

abstract：:The effects of anisodamine on acetylcholine-induced endothelium-dependent relaxation were studied in organ chambers and under bioassay conditions. In organ chamber experiments, both acetylcholine and bradykinin induced an endothelium-dependent relaxation of norepinephrine-contracted canine femoral arteries in a concen...

journal_title：Chinese medical journal

authors： Guo HY,Loren RR,Vanhutte PM

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Programmed cell death 5 (PDCD5) is a novel apoptotic regulatory gene that promotes apoptosis in various tumor cells. Studies have shown that PDCD5 accelerates the apoptosis of synoviocytes in vitro, implying a potential role in rheumatoid arthritis (RA) pathogenesis. This study examined the expression of PDC...

journal_title：Chinese medical journal

authors： Wang JF,Guan ZP,Zhang SL,Pei Z,Chen YY,Pan H

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between the presence of the TNF2 allele and plasma concentrations of tumor necrosis factor-alpha (TNF alpha) and soluble TNF receptor (sTNF-R) with the development of acute severe pancreatitis (ASP) and severe sepsis. METHODS:Genomic DNA was prepared from peripheral blood leuk...

journal_title：Chinese medical journal

authors： Zhang D,Li J,Jiang Z,Yu B,Tang X,Li W

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The effectiveness of neoadjuvant chemoradiotherapy (NCRT) treatment for patients with esophageal carcinoma (EC) remains controversial. The aim of this study was to compare the effect of NCRT followed by surgery (NCRTS) with surgery alone (SA) for EC. METHODS:The PubMed, EMBASE, and the Cochrane Library data...

journal_title：Chinese medical journal

authors： Wang DB,Sun ZY,Deng LM,Zhu DQ,Xia HG,Zhu PZ

更新日期：2016-12-20 00:00:00

abstract：:The phenotypes of mononuclear cells in 16 patients with mycosis fungoides (MF) (8 were in tumor stage and 8 in pretumor stage) were tested by ABC immunochemical technique. The results showed that the percentage of CD38 and Leu6(+) cells in tumor stage was higher than that in pretumor stage. CD38 was identified to be a...

journal_title：Chinese medical journal

authors： Liu JH,Zhang Q,Shi YF,Zeng XS,Wang XH,Li J,Chen Z,Shen DC

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Antiplatelet therapy (APT) was prevalently being used in the prevention of vascular disease, but the influence of prior APT on the prognosis of patients with intracerebral hemorrhage (ICH) remains controversial. This meta-analysis was to explore the effects of prior APT on the prognosis of patients with prim...

journal_title：Chinese medical journal

authors： Yu HH,Pan C,Tang YX,Liu N,Zhang P,Hu Y,Zhang Y,Wu Q,Deng H,Li GG,Li YY,Nie H,Tang ZP

更新日期：2017-12-20 00:00:00

abstract：OBJECTIVE:To study the relationship between cartilage end-plate calcification and intervertebral disc degeneration. METHODS:An experimental model of cervical disc degeneration in rabbits was established by resection of the cervical supraspinous and interspinous ligaments and detachment of the posterior paravertebral m...

journal_title：Chinese medical journal

authors： Peng B,Hou S,Shi Q,Jia L

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To summarize the progress of surgical treatment of hepatocellular carcinoma (HCC) and related basic research at the Liver Cancer Institute of Shanghai Medical University in the recent years, with special reference to recurrence and metastasis. METHODS:Published and unpublished update clinical and experimenta...

journal_title：Chinese medical journal

authors： Tang Z,Zhou X,Lin Z,Yang B,Ma Z,Ye S,Wu Z,Fan J,Liu Y,Liu K,Qin L,Tian J,Sun H,He B,Xia J,Qiu S,Zhou J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:At present, revascularization is still one of the most critical technologies in orthotopic liver transplantation (OLT). Hepatic artery (HA) variations occur frequently in both donors and recipients. Moreover, there are always some pathological changes in the recipient hepatic artery. If handled improperly, i...

journal_title：Chinese medical journal

authors： Ma Y,Li Q,Ye ZM,Zhu XF,He XS

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a squamous-cell carcinoma especially prevailing among the natives of southern China. The regimen of concurrent chemoradiotherapy (CCRT) that include platinum and 5-fluorouracil (5-FU) is considered to be the standard treatment for NPC. However, its clinical use is limited by...

journal_title：Chinese medical journal

authors： Chen X,Hong Y,Feng J,Ye J,Zheng P,Guan X,You X,Song H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Phosphorous magnetic resonance spectroscopy ((31)P-MRS) has been successfully applied to study intracellular membrane compounds and high-energy phosphate metabolism. This study aimed to evaluate the capability of dynamic (31)P-MRS for assessing energy metabolism and mitochondrial function in skeletal muscle ...

journal_title：Chinese medical journal

authors： Wu FY,Tu HJ,Qin B,Chen T,Xu HF,Qi J,Wang DH

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To assess the value of noninvasive three-dimensional computed tomographic angiography (3D-CTA) in preoperative detection of intracranial arteriovenous malformations (AVMs). METHODS:A prospective evaluation at a single institute over a 2-year period included 23 patients suspected of intracranial AVMs. All pat...

journal_title：Chinese medical journal

authors： Wu J,Chen X,Shi Y,Chen S

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:To explore the involvement of calcium in the mechanism of hypoxic/hypoglycemic insults and nerve growth factor (NGF) protection. METHODS:Neuron viability and lactate dehydrogenase (LDH) efflux in the bathing medium in cerebral cortex cultures from fetal rats were measured. Calcium fluorescent indicator Fura-...

journal_title：Chinese medical journal

authors： Wu J,Zhang J

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:In county-level tuberculosis (TB) dispensaries in China, the accurate diagnosis of sputum smear-negative pulmonary tuberculosis (SNPT) needs to be improved by developing and validating clinical and radiographic predictors. METHODS:The study was conducted simultaneously in three counties per province in Chon...

journal_title：Chinese medical journal

authors： Li XX,Jiang SW,Zhang H,Jing KH,Wang L,Li WB,Liu XQ,Yao HY,Wang LX

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Studies have shown that β-blockers can improve cardiac performance in heart failure (HF) by reversing protein kinase A (PKA)-mediated sarcoplasmic reticulum (SR) Ca2+ leak. However, it is being strongly questioned as to whether the PKA-mediated ryanodine receptor (RyR2) hyper-phosphorylation is a critical re...

journal_title：Chinese medical journal

authors： Zhang SJ,Liu ZH,Zou C,Wang L

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The tibial plateau is asymmetric with a larger medial plateau. We observed from clinical practice that the shape of the tibial plateau does not always present a larger medial plateau. Tibial plateau also showed other shapes. The purpose of this study was to analyze the anthropometric data of the proximal tib...

journal_title：Chinese medical journal

authors： Yang B,Yu J,Gong X,Chen L,Wang Y,Wang J,Wang H,Zhang J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:HIV-1 infected and immune-activated macrophages and microglia secrete neurotoxins, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which play major role in the neuronal death. It has been shown that different HIV-1 variants have varying abilities to elicit secretion of TNF-α by peripheral...

journal_title：Chinese medical journal

authors： Yan YF,Wang ZY,Pu SS,Wen HL,Huang T,Song YY,Xu HZ,Zhao L

更新日期：2011-12-01 00:00:00