Anisodamine inhibits acetylcholine-induced endothelium-dependent relaxation of canine femoral artery.

abstract：BACKGROUND:Pulmonary problems often occur in patients with early-onset scoliosis (EOS). However, lung function in patients with EOS after growing rod surgery has not been documented. The aim of this study was to investigate lung function after the treatment for EOS with growing rod and its possible correlative factors....

journal_title：Chinese medical journal

authors： Jiang Y,Zhao Y,Wang YP,Qiu GX,Weng XS,Li Y

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric carcinoma, which has its unique clinicopathological features and poorer prognosis than that of the ordinary gastric adenocarcinoma. At present, there is still a lack of understanding about this disease. The current study aimed to summariz...

journal_title：Chinese medical journal

authors： Zhang JF,Shi SS,Shao YF,Zhang HZ

更新日期：2011-05-01 00:00:00

abstract：:Diabetes mellitus and pancreatic ductal adenocarcinoma are two common diseases worldwidely which are both derived from different components of pancreas. The pancreatic and duodenal homeobox-1 (PDX1) is an essential transcription factor for the early development of pancreas that is required for the differentiation of a...

journal_title：Chinese medical journal

authors： Tang ZC,Chu Y,Tan YY,Li J,Gao S

更新日期：2020-02-05 00:00:00

abstract：BACKGROUND:Collagen VI-related myopathies are autosomal dominant and recessive hereditary myopathies, mainly including Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM). Muscle magnetic resonance imaging (MRI) has been widely used to diagnosis muscular disorders. The purpose of this study was to ev...

journal_title：Chinese medical journal

authors： Fu J,Zheng YM,Jin SQ,Yi JF,Liu XJ,Lyn H,Wang ZX,Zhang W,Xiao JX,Yuan Y

更新日期：2016-08-05 00:00:00

abstract：BACKGROUND:Aquired immune deficiency syndrome (AIDS) presents a challenge to medical researchers because of its unique pathological and clinical picture. The clinical data, particularly autopsy evidence, from China have failed to provide enough pathological and etiological evidence for AIDS diagnosis, which impairs the...

journal_title：Chinese medical journal

authors： Li HJ,Gao YQ,Cheng JL,Zhang YZ

更新日期：2009-09-20 00:00:00

abstract：Background::Localized macular edema and retinal nerve fiber layer (RNFL) thinning have been reported shortly after laser in situ keratomileusis (LASIK) in adults. However, it is still unclear how LASIK affects the retina of children. This study aimed to investigate the macular retina and RNFL thickness in children with...

journal_title：Chinese medical journal

authors： Zhao PF,Zhou YH,Zhang J,Wei WB

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND:Borderline gastrointestinal stromal tumors (GISTs) are intermediate tumors between benign and malignant variants; however, the clinical and pathological features of borderline GISTs remain poorly defined. This study aimed to characterize GISTs and to identify a set of borderline criteria for practical use. ...

journal_title：Chinese medical journal

authors： Shi Y,Hou YY,Lu SH,Zhou Y,Xu JF,Ji Y,Hou J,Xu C,Liu YL,Tan YS,Zhu XZ

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To assess the feasibility of detecting SYT-SSX fusion transcripts in paraffin-embedded tissues of synovial sarcoma by reverse transcription-polymerase chain reaction (RT-PCR). METHODS:RT-PCR was used to amplify the SYT-SSX fusion transcripts using archival formalin-fixed paraffin-embedded tumor specimens fro...

journal_title：Chinese medical journal

authors： Wei Y,Wang J,Zhu X,Shi D,Hisaoka M,Hashimoto H

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The prevalence of sudden sensorineural hearing loss in children (CSSNHL) is consistently increasing. However, the pathology and prognosis of CSSNHL are still poorly understood. This retrospective study evaluated clinical characteristics and possible associated factors of CSSNHL. METHODS:One hundred and thir...

journal_title：Chinese medical journal

authors： Li FJ,Wang DY,Wang HY,Wang L,Yang FB,Lan L,Guan J,Yin ZF,Rosenhall U,Yu L,Hellstrom S,Xue XJ,Duan ML,Wang QJ

更新日期：2016-04-20 00:00:00

abstract：BACKGROUND:Cubital tunnel syndrome is a well-recognized clinical condition and is the second most common peripheral compression neuropathy. This study was designed to investigate the causes of cubital tunnel syndrome by surgical means and to assess the clinical value of the neurophysiological diagnosis of cubital tunne...

journal_title：Chinese medical journal

authors： Jia ZR,Shi X,Sun XR

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. In this study, we collected a Han monilethrix family to detect the mutations in patients and investigated the correlation between the genotype and phenotype of monilethrix. METHODS:In this study, ...

journal_title：Chinese medical journal

authors： Ye ZZ,Nan X,Zhao HS,Chen XR,Song QH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease, affecting about 0.6% of the Chinese population. Many patients are not well controlled by conventional treatments, thus there is need for new treatment regimens. In this study, we assessed the efficacy and safety of secukinumab in Chinese patients with moderat...

journal_title：Chinese medical journal

authors： Cai L,Zhang JZ,Yao X,Gu J,Liu QZ,Zheng M,Zhang SF,Xu JH,Li CX,Cheng H,Guo Q,Pan WL,Li SQ,Li RY,Guo ZP,Song ZQ,Li SS,Dong XQ,Wang L,Fu R,Regnault P,Charef P,Mazur R,Patekar M

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Diabetes mellitus plays an important role in cancer prevalence and outcomes. The aim of this study was to evaluate the influence of DM on stages and outcomes among patients with colorectal cancer. METHODS:The study enrolled 945 patients who were diagnosed as having colorectal carcinoma from August 1994 to D...

journal_title：Chinese medical journal

authors： Chen CQ,Fang LK,Cai SR,Ma JP,Yang GX,Yang W,Zhan WH,He YL

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Fractional flow reserve (FFR) has become an increasingly important index when making decisions with respect to revascularization of coronary artery stenosis. However, the pressure guidewire used in obtaining FFR measurements is difficult to control and manipulate in certain complex coronary artery lesions, r...

journal_title：Chinese medical journal

authors： He WM,Li CL,Sun Y,Zhou Z,Mai YF

更新日期：2015-03-20 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Du J,Yang XW,Wen ZJ,Xue C,Wu YM,Wu MC,Zhang LL

更新日期：2018-10-20 00:00:00

abstract：BACKGROUND:Difficulties persist in differentiating pancreatic ductal adenocarcinomas (PDAC) from pancreatic inflammatory masses (PIM). Auxiliary diagnostic techniques which enhance the endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) diagnostic yield have been attempted, for example, K-ras mutation analysi...

journal_title：Chinese medical journal

authors： Xu Y,Hu D,Zhu Q,Sun Y

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate an method for hepatic differentiation from embryonic stem cells (ES cells) in vitro and the resulting differentiation ratio, in order to develop a procedure for producing a new type of hepatocyte for hepatocyte replacement therapy in the treatment of liver failure. METHODS:ES cells from Balb/C...

journal_title：Chinese medical journal

authors： Hu A,Cai J,Zheng Q,He X,Pan Y,Li L

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To clarify whether genetic variants of the renin-angiotensin system (RAS) contribute to the development of diabetic nephropathy (DN) in the Chinese. METHODS:Totally 173 Chinese subjects of Han nationality from Shanghai were classified into! control, DN (-) and DN (+) groups. The latter was subdivided accordi...

journal_title：Chinese medical journal

authors： Wu S,Xiang K,Zheng T,Sun D,Weng Q,Zhao H,Li J

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:To study the ultrastructural damages of brain tissues dynamically after middle cerebral artery obstruction (MCAO). METHODS:A middle cerebral artery obstruction (MCAO) model was reproduced in renal vascular hypertensive rats (RHR). Brain tissues in different locations were collected for eight times in row, fr...

journal_title：Chinese medical journal

authors： Fang Y,Huang R,Su Z,Lin J,Li J

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Pulmonary endarterectomy is safe and effective surgical treatment for chronic thromboembolic pulmonary hypertension. This study aimed to evaluate the efficacy of pulmonary endarterectomy in treatment of thromboembolic pulmonary hypertension. METHODS:A retrospective study of 15 patients who underwent pulmona...

journal_title：Chinese medical journal

authors： Gu S,Liu Y,Su PX,Zhai ZG,Yang YH,Wang C

更新日期：2010-04-20 00:00:00

abstract：BACKGROUND:The rapid transmission and high mortality rate made severe acute respiratory syndrome (SARS) a global threat for which no efficacious therapy is available now. Without sufficient knowledge about the SARS coronavirus (SARS-CoV), it is impossible to define the candidate for the anti-SARS targets. The putative ...

journal_title：Chinese medical journal

authors： Lu JH,Zhang DM,Wang GL,Guo ZM,Zhang CH,Tan BY,Ouyang LP,Lin L,Liu YM,Chen WQ,Ling WH,Yu XB,Zhong NS

更新日期：2005-05-05 00:00:00

abstract：OBJECTIVE:To determine the feasibility and accuracy of high-frequency ultrasound in evaluating the left ventricular (LV) structure and function in normal and pressure overload rats and to examine the changes of the left ventricle during its transition from hypertrophy to heart failure. METHODS:Thirty-eight female rats...

journal_title：Chinese medical journal

authors： Xu F,Wang J,Bai X,Yang J,Bai S

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To characterize the mRNA expression of CXC chemokine IL-8, CC chemokine monocyte chemothractant protein-1 (MCP-1) and regulated on activation, normal T cell expressed and secreted (RANTES), and a newly defined DC chemokine DC-CK1 as well as the expression of IL-8 receptor, MCP-1 receptor and RANTES receptor i...

journal_title：Chinese medical journal

authors： Zhu K,Shen Q,Ulrich M,Zheng M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Cigarette smoke induces an acute but persisting inflammation in peripheral blood and airway in chronic obstructive pulmonary disease (COPD), and CD8(+) Tc-lymphocytes are considered as a key role in this process. We aimed to investigate the Tc-lymphocytes immunodeviation in system and local airway of COPD pa...

journal_title：Chinese medical journal

authors： Yu MQ,Liu XS,Wang JM,Xu YJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) may affect varied and complex physiology processes by manipulating Ca(2+)-calmodulin (CaM). However, the detailed mechanism about the action of VAs on CaM has not been elucidated. This study was undertaken to examine the effects of VAs on the conformational change, hydrophobic site...

journal_title：Chinese medical journal

authors： Zhou MM,Xia HM,Liu J,Xu YN,Xin NX,Zhang SH

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:As an X-linked recessive way, arginine vasopressin receptor 2 (AVPR2) gene mutation resulted in a hereditary disease - congenital nephrogenic diabetes insipidus (CNDI). We found a suspect clinical CNDI pedigree. In order to identify the genetic etiology, we performed the genetic analysis. METHODS:The clinic...

journal_title：Chinese medical journal

authors： Shen Y,Lai X,Xiao X,Li J,Yu R,Gao H,Zhang M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Associations between glutamine (Gln) enriched nutrition support and surgical patients with gastrointestinal (GI) tumor remain controversy. The purpose of this meta-analysis was to assess the effect of Gln enriched nutrition support on surgical patients with GI tumor in term of relevant biochemical indices, i...

journal_title：Chinese medical journal

authors： Kang K,Shu XL,Zhang YS,Liu XL,Zhao J

更新日期：2015-01-20 00:00:00

abstract：BACKGROUND:CD4(+)CD25(+) regulatory T cells (Tregs) mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), and transforming growth factor beta (TG...

journal_title：Chinese medical journal

authors： Zhang Q,Qian FH,Liu H,Zhou LF,Huang M,Zhang XL,Yin KS

更新日期：2008-02-05 00:00:00

abstract：OBJECTIVE:To review the implications for diagnosis, pathogenesis and potential for new therapeutic option for chronic neutrophilic leukemia (CNL). DATA SOURCES:Data cited in this review were obtained mainly from PubMed and Medline from 1993 to 2013 and highly regarded older publications were also included. The terms "...

journal_title：Chinese medical journal

authors： Otgonbat A,Zhao M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To discuss the etiology, diagnostic criteria and treatment of Nelson's syndrome. METHODS:Twenty-three patients with Nelson's syndrome who were treated in our department over the last 19 years were analyzed retrospectively. Removal of adenoma by the transsphenoidal approach was done in 21 patients and by tran...

journal_title：Chinese medical journal

authors： Xing B,Ren Z,Su C,Wang R,Yang Y,Hu Y

更新日期：2002-08-01 00:00:00