Transitional cell carcinoma associated with aristolochic acid nephropathy: most common cancer in chronic hemodialysis patients in China.

abstract：:The depth and area-percentage of Alcian blue (AB) staining of glomeruli, the ability of RBC to bind AB and the onset of proteinuria in adriamycin nephrosis in rats were studied. The results showed that the negative charge (NC) on RBC and glomeruli decreased significantly after injection of adriamycin and there was a p...

journal_title：Chinese medical journal

authors： Chen ZY,Jiang XY

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) could be induced to differentiate into insulin producing cells (IPCs) in vitro, which have good application potential in the cell replacement treatment of type-1 diabetes. However, the mechanisms regulating this differentiation have remaine...

journal_title：Chinese medical journal

authors： Hu YH,Wu DQ,Gao F,Li GD,Zhang XC

更新日期：2010-03-05 00:00:00

abstract：OBJECTIVE:To investigate the role of a potential diabetes-related mitochondrial region, which includes two previously reported mutations, 3243A-->G and 3316G-->A, in Chinese patients with adult-onset type 2 diabetes. METHODS:A total of 277 patients and 241 normal subjects were recruited for the study. Mitochondrial nt...

journal_title：Chinese medical journal

authors： Yang T,Lam CW,Tsang MW,Tong SF,Kam GY,Chan LY,Poon PM,Wu X,Pang CP

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The development of the targeted signal transduction inhibitor STI571 has prompted us to treat chronic myeloid leukemia in different ways. Since STI571 may reverse multidrug-resistance of K562/MDR cells in vitro, we studied the effect of STI571 on multidrug-resistant K562 cells in vivo. METHODS:Multidrug-res...

journal_title：Chinese medical journal

authors： Gao L,Chen L,Fei XH,Qiu HY,Zhou H,Wang JM

更新日期：2006-06-05 00:00:00

abstract：OBJECTIVES:To get a more comprehensive recognition about carpal tunnel syndrome (CTS), especially the manual housework as its risk factor, and to facilitate early diagnosis and proper treatment. METHODS:262 CTS patients (396 CTS hands) were analyzed retrospectively. A 1:1 matched case-control study of 61 woman pairs i...

journal_title：Chinese medical journal

authors： Tang X,Zhuang L,Lu Z

更新日期：1999-01-01 00:00:00

abstract：:The protective effect of improving the microcirculation on the retinal ganglion cells (RGC) and the ultrastructure of the optic nerve after intravenous (i.v.) use of Salviae miltiorrhiza (SMR) was studied in a chronic intraocular hypertension model in 36 rabbits. These rabbits were treated with topical 0.5% timolol, o...

journal_title：Chinese medical journal

authors： Zhu MD,Cai FY

更新日期：1993-12-01 00:00:00

abstract：Background:The role of postradiation systemic therapy in non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) was controversial. Thus, we explored the role of Radiation Therapy Oncology Group recursive partitioning analysis (RTOG-RPA) and graded prognostic assessment (GPA) in identifying population wh...

journal_title：Chinese medical journal

authors： Liu S,Chen P,Liu YW,Gu XN,Qiu XG,Li B

更新日期：2018-05-20 00:00:00

abstract：:Selective ablation of slow pathway by radiofrequency (RF) current in 34 patients with atrioventricular (AV) node pathways and tachycardia was performed with two methods in our section; posterior approach was used in the first 12 patients, the slow pathways were ablated successfully. Inferior approach was performed in ...

journal_title：Chinese medical journal

authors： Hu DY,Ding YS,Ma CS,Li YG,Li YF,Wang LX,Wang LH

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Chronic hepatic inflammation is characterized by the accumulation of lymphocytes as a consequence of increased recruitment from the blood and retention within the tissue at sites of infection. CXC chemokine ligand 16 (CXCL16) mRNA has been detected in both inflamed and normal liver tissues and is strongly up...

journal_title：Chinese medical journal

authors： Wang P,Kan QC,Yu ZJ,Li L,Pan X

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Although previous reports had reported the use of temporary internal distraction as an aid to correct severe scoliosis, two-stage surgery strategy (less invasive internal distraction followed by posterior correction and instrumentation) has never been reported in the treatment of patients with severe spinal ...

journal_title：Chinese medical journal

authors： Tan R,Ma HS,Zou DW,Wu JG,Chen ZM,Zhou XF,Zhou JW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Antiphospholipid syndrome (APS)-related immune factors are considered as an important cause of recurrent spontaneous abortion (RSA). Anticoagulant and anti-inflammatory treatments are believed to effectively improve adverse pregnancy outcomes by affecting the abnormal autoimmune response of the maternal-feta...

journal_title：Chinese medical journal

authors： Ye SL,Gu XK,Tao LY,Cong JM,Wang YQ

更新日期：2017-06-20 00:00:00

abstract：:The effects of hypoxic endothelial cell conditioned medium (HECCM) on proliferation and collagen synthesis of cultured porcine pulmonary arterial smooth muscle cells (PASMCs) were studied by 3H-thymidine (3H-TdR) and 3H-proline incorporations, image analysis for determination of DNA content and colorimetric assay usin...

journal_title：Chinese medical journal

authors： Sun B,Yuan Y,Zhang W,Che D

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Coexistent carotid and coronary artery diseases are common and patients with them remain at a high risk for perioperative stroke or myocardial infarction after coronary bypass surgery. The aim of this study was to investigate the effect of combined carotid endarterectomy (CEA) and off-pump coronary artery by...

journal_title：Chinese medical journal

authors： Chen XJ,Chen X,Xie DH,Shi KH,Xu M

更新日期：2009-12-20 00:00:00

abstract：BACKGROUND:Estrogen receptor (ER)-negative breast cancer cells are more aggressive than ER-positive cells. Elevated levels of cyclooxygenase-2 (COX-2) and vascular endothelial growth factor-C (VEGF-C) expression have been detected in cultured human breast cancer cells and are associated with negative hormone receptor s...

journal_title：Chinese medical journal

authors： Zhang H,Lin Y,Xiao Y,Wang SM,Liu XX,Wang SM

更新日期：2010-08-05 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most globally prevalent cancers in the world. The pathogenesis of GC has not been fully elucidated, and there still lacks effective targeted therapeutics. The influence of altered kinesin superfamily protein 22 (KIF22) expression in GC progression is still unclearly. The aim...

journal_title：Chinese medical journal

authors： Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:The cell layer of the ciliary epithelium is responsible for aqueous humor secretion and maintenance. Ion channels play an important role in these processes. The main aim of this study was to determine whether the well-characterized members of the Kv1 family (Kv1.3) contribute to the Kv currents in ciliary ep...

journal_title：Chinese medical journal

authors： Li YF,Zhuo YH,Bi WN,Bai YJ,Li YN,Wang ZJ

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair (TEVAR) is an emerging treatment modality, which has been rapidly embraced by clinicians treating thoracic aortic disease. However, the clinical manifestations of systemic inflammatory response after TEVAR as post-implantation syndrome (PIS) resemble the perioperative infe...

journal_title：Chinese medical journal

authors： Xue L,Luo S,Luo J,Liu Z,Gu M,Kang H,Yang F,Nie B,Liu Y,Huang W,Xie N,He P,Dong H,Ni Z,Fan R,Chen J

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To review the recent developments in the mechanisms of glucocorticoids induced osteonecrosis of femoral head (ONFH) and introduce a new theory of ONFH. DATA SOURCES:Both Chinese- and English-language literatures were searched using MEDLINE (1997 - 2011), Pubmed (1997 - 2011) and the Index of Chinese-language...

journal_title：Chinese medical journal

authors： Tan G,Kang PD,Pei FX

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features, operative methods and postoperative management of the intra-axial tumors of medullocervical junction, and to make differential diagnosis for different subtypes. METHODS:Fifteen patients with intra-axial tumors of medullocervical junction were treated from August 1988 to Jun...

journal_title：Chinese medical journal

authors： Xu Q,Bao W,Mao R,Pang L

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target. DATA SOURCES:This study was based on data obtained from PubMed and EMBASE up to June 30, 2015. Articles were selected using the following se...

journal_title：Chinese medical journal

authors： Liu TX,Niu HT,Zhang SY

更新日期：2015-10-20 00:00:00

abstract：BACKGROUND:Monolayer cell culture models are the traditional culture models used for in vitro research of pancreatic carcinoma chemosensitivity. However, these models neglect the interactions between tumor cells and the impact of the tumor microenvironment. Such tumor cell monolayers poorly mimic the solid tumor microe...

journal_title：Chinese medical journal

authors： Liao Q,Hu Y,Zhao YP,Zhou T,Zhang Q

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes has been recognized as an organ specific autoimmune disease owing to the immune destruction of pancreatic islet beta cells in genetically susceptible individuals. In both human and rodent models of type 1 diabetes, such as nonobese diabetic (NOD) mice, biobreeding rats, the disease has a dist...

journal_title：Chinese medical journal

authors： Li D,Zhu SW,Liu DJ,Liu GL,Shan ZY

更新日期：2005-08-05 00:00:00

abstract：OBJECTIVE:To determine the effects and toxicity of interstitial brachytherapy using iridium-192 on brain malignant gliomas. METHODS:Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high-activity iridi...

journal_title：Chinese medical journal

authors： Liu Z,Yu X,Guo Y,Li S,Cui Y,Yu X,Yuan Z,Kang J

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Our previous studies have shown that both apoptosis and necrosis are involved in hair cell (HC) pathogenesis in aging cochleae. To better understand the biological mechanisms responsible for the regulation of HC death, we examined the activity of succinate dehydrogenase (SDH), a mitochondrial bioenergetic en...

journal_title：Chinese medical journal

authors： Yang WP,Hu BH,Sun JH,Zhai SQ,Henderson D

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Functional neuroimaging study has opened an avenue for exploring the pathophysiology of cluster headache (CH). The aim of our study was to assess the changes in brain activity in CH patients by the regional homogeneity method using resting-state functional magnetic resonance imaging technique. METHODS:The f...

journal_title：Chinese medical journal

authors： Qiu EC,Yu SY,Liu RZ,Wang Y,Ma L,Tian LX

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Cochlear implants (CIs) can improve speech recognition for children with severe congenital hearing loss, and open-set word recognition is an important efficacy measure. This study examined Mandarin open-set word recognition development among Chinese children with CIs and normal hearing (NH). METHODS:This st...

journal_title：Chinese medical journal

authors： Kong Y,Liu X,Liu S,Li YX

更新日期：2017-10-20 00:00:00

abstract：BACKGROUND:Isocitrate lyase (ICL) was previously demonstrated to play a pivotal role in the intracellular metabolism of Mycobacterium tuberculosis (MTB). Presently several lines of evidence suggest that ICL from MTB (MTB-ICL) may play some roles in the interaction between MTB and host macrophage. However, there has bee...

journal_title：Chinese medical journal

authors： Li JM,Li N,Zhu DY,Wan LG,He YL,Yang C

更新日期：2008-06-20 00:00:00

abstract：BACKGROUND:Periostin originally designated osteoblast-specific factor 2 (OSF-2) is frequently found to be highly expressed in various types of human cancer cell lines in vitro and human cancer tissues in vivo. We proposed that periostin was a key factor during the process of proliferation and invasion in cancer cells. ...

journal_title：Chinese medical journal

authors： Liu C,Huang SJ,Qin ZL

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out the associations between cortex-involved stroke, vascular risk factors, and the subtypes (discovery time ...

journal_title：Chinese medical journal

authors： Li SY,Yang XM,Zhao XQ,Liu LP,Wang YL,Jiang Y,Wang YJ

更新日期：2019-09-05 00:00:00

abstract：OBJECTIVE:To study the interruptive effect of hepatitis B virus (HBV) specific immunolobulin (HBIG) before delivery in attempt to prevent intrauterine transmission of HBV. METHODS:Nine hundred and eighty HBsAg carrier pregnant women were randomly divided into HBIG group and control group. Each subject in the HBIG grou...

journal_title：Chinese medical journal

authors： Zhu Q,Yu G,Yu H,Lu Q,Gu X,Dong Z,Zhang X

更新日期：2003-05-01 00:00:00