Assessment of pancreatic carcinoma cell chemosensitivity using a three-dimensional culture system.

abstract：BACKGROUND:This prospective, randomized, controlled study was designed to investigate the effects of a diabetes specific formula (Diason low energy: 313.8 kJ/100 ml), compared with a standard formula, on insulin sensitivity, serum C peptide, serum lipids and free fatty acid (FFA) in type 2 diabetics. METHODS:In total ...

journal_title：Chinese medical journal

authors： Li YX,Zeng JB,Yu K,Sun Q,Liu QY,Qin W,Zhang Q,Yu JC,Wang H

更新日期：2008-04-20 00:00:00

abstract：BACKGROUND:Visfatin, a visceral fat-derived adipocytokine, plays a significant physiological function in lipid metabolism. However, the precise function of visfatin and its regulation by thyroid hormones are still unknown. This study observed the plasma visfatin concentrations in subjects with hyperthyroidism and hypot...

journal_title：Chinese medical journal

authors： Han J,Zhang TO,Xiao WH,Chang CQ,Ai H

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out the associations between cortex-involved stroke, vascular risk factors, and the subtypes (discovery time ...

journal_title：Chinese medical journal

authors： Li SY,Yang XM,Zhao XQ,Liu LP,Wang YL,Jiang Y,Wang YJ

更新日期：2019-09-05 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) is commonly utilized as part of the diagnostic workup for the clinical diagnosis of glioblastoma multiforme (GBM), further guiding the clinical treatment of this aggressive cancer. Recent research has shown that microRNAs (miRNAs) may act as oncogenes, or in some cases, tumor...

journal_title：Chinese medical journal

authors： Li WB,Chen HY,Zhang W,Yan W,Shi R,Li SW,Jiang T

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To improve the prognosis and therapeutic efficacy of Waldeyer's ring non-Hodgkin lymphoma (NHL-WR), combined radio-chemotherapy was used to treat the patients with NHL-WR and prognostic factors were analyzed. METHODS:Ninety patients with stage I-IV NHL-WR were treated with combined radio-chemotherapy. 4000 c...

journal_title：Chinese medical journal

authors： Yong W,Zhang Y,Zheng W,Wei Y

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2), one of the major metabolites from prostaglandin D2 in arachidonic acid metabolic pathway, has potential anti-inflammatory properties. The objective of this study was to explore the effects of 15d-PGJ2-loaded poly(D,L-lactide-co-glycolide) nanocapsules (15d-PGJ2-NC...

journal_title：Chinese medical journal

authors： Tang Q,Chen LL,Wei F,Sun WL,Lei LH,Ding PH,Tan JY,Chen XT,Wu YM

更新日期：2017-02-05 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is thought to be an inflammatory immune response disease. In most cases, the disease is caused by cigarette smoke, but it has been demonstrated that only 10% to 20% of smokers will definitely suffer from COPD. Dendritic cells (DCs) are considered to be the promote...

journal_title：Chinese medical journal

authors： Su YW,Xu YJ,Liu XS

更新日期：2010-06-01 00:00:00

abstract：:A 16-year-old female patient with systemic lupus erythematosus (SLE) presented with abdominal pain and oliguria, after one month of hospital treatment with methylprednisolone and cyclophosphamide. Computed tomography of the abdomen revealed the calcification of bilateral superior segmental ureteral wall. Computed tomo...

journal_title：Chinese medical journal

authors： Jiang DX,Liao Y,Bai YJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) is one of the most globally prevalent cancers in the world. The pathogenesis of GC has not been fully elucidated, and there still lacks effective targeted therapeutics. The influence of altered kinesin superfamily protein 22 (KIF22) expression in GC progression is still unclearly. The aim...

journal_title：Chinese medical journal

authors： Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:CD4(+)CD25(+) regulatory T cells (Tregs) mediate immune suppression through cell-cell contact with surface molecules, particularly cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR), and transforming growth factor beta (TG...

journal_title：Chinese medical journal

authors： Zhang Q,Qian FH,Liu H,Zhou LF,Huang M,Zhang XL,Yin KS

更新日期：2008-02-05 00:00:00

abstract：:To develop a more comprehensive index for predicting the prognous of liver cirrhosis. 300 consecutive patients with cirrhosis were studied in terms of survival from 1975 to 1986. Median follow-up period was 5.3 years. A multivariable survival analysis (Cox's regression model) using clinical biochemical data obtained a...

journal_title：Chinese medical journal

authors： Wang JY,Liu HY,Zhu WN,Han JQ,Dong CY,Shi YJ,Cai HJ,Cao JM,Yi QL

更新日期：1989-04-01 00:00:00

abstract：:Anastomotic false aneurysm (AFA) of the aorta is a potentially lethal complication after prosthetic grafting. Nineteen aneurysms were encountered in 18 patients within a 30-year period (1960-1991). There were 10 men and 8 women, aged 27-80 years (mean 58 years). In 14 patients, the prostheses were made of silk, in 2 w...

journal_title：Chinese medical journal

authors： Chen FZ,Xu X,Fu WG,Wu ZG

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The efficacy of pemetrexed in the second-line treatment of Chinese patients with advanced non-small cell lung cancer (NSCLC) has been shown to be similar to that of docetaxel in a recent study; additionally, pemetrexed was associated with much better safety and toxicity profiles. Here, the survival without c...

journal_title：Chinese medical journal

authors： Wu YL,Sun Y,Zhou CC,Zhang L,Yu SY,Ma SL,Han LL,Zhang XQ,Orlando M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem or stromal cells (MSCs) derived from the induced pluripotent stem cells (iPSCs) have uniform biological activity, which makes the clinical application of MSCs in bone repair possible. Culturing the iPSC-MSCs onto osteoconductive materials is a promising tissue engineering-based strategy in b...

journal_title：Chinese medical journal

authors： Li JY,Wang TT,Li C,Wang ZF,Li S,Ma L,Zheng LL

更新日期：2020-02-05 00:00:00

abstract：OBJECTIVE:To understand whether very low density lipoprotein (VLDL) and oxidatively modified very low density lipoprotein (OX-VLDL) can stimulate vascular smooth muscle cells (SMCs) to express high level of monocyte chemotactic protein (MCP-1) mRNA. METHODS:LDL and VLDL were isolated from normal blood donors by densit...

journal_title：Chinese medical journal

authors： Ruan Q,Deng Z,Song J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Porcine liver performing efficient physiological functions in the human body is prerequisite for successful liver xenotransplantation. However, the protein differences between pig and human remain largely unexplored. Therefore, we investigated the liver expression profile of a highly inbred minipig line. ME...

journal_title：Chinese medical journal

authors： Chen YN,Tan WD,Lu YR,Qin SF,Li SF,Zeng YZ,Bu H,Li YP,Cheng JQ

更新日期：2007-05-05 00:00:00

abstract：BACKGROUND:Isocitrate lyase (ICL) was previously demonstrated to play a pivotal role in the intracellular metabolism of Mycobacterium tuberculosis (MTB). Presently several lines of evidence suggest that ICL from MTB (MTB-ICL) may play some roles in the interaction between MTB and host macrophage. However, there has bee...

journal_title：Chinese medical journal

authors： Li JM,Li N,Zhu DY,Wan LG,He YL,Yang C

更新日期：2008-06-20 00:00:00

abstract：BACKGROUND:The efficacy of percutaneous intradiscal radiofrequency thermocoagulation (PIRFT) for the treatment of discogenic low back pain (LBP) remains controversial. However, all the PIRFT studies utilized monopolar radiofrequency thermocoagulation (RFTC). The aim of this study was to investigate the safety and effic...

journal_title：Chinese medical journal

authors： Zhang L,Ding XL,Zhao XL,Wang JN,Li YP,Tian M

更新日期：2016-10-05 00:00:00

abstract：BACKGROUND:Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening complication occurring in the third trimester. It is often fatal to both mother and fetus. The complicated clinical manifestations as well as an insufficient understanding of the disease make the precise diagnosis and effective treatment of...

journal_title：Chinese medical journal

authors： Zhang YP,Kong WQ,Zhou SP,Gong YH,Zhou R

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:Congenital heart disease (CHD) is a common heart condition which does considerable harm to the health of children and adolescents. CHD epidemiological characteristics of Tibetan children whose ages ranged from 4 to 18 years were investigated in Qinghai Province. METHODS:A total of 32 578 Tibetan children, l...

journal_title：Chinese medical journal

authors： Chen QH,Wang XQ,Qi SG

更新日期：2008-12-20 00:00:00

abstract：BACKGROUND:Three randomised trials have demonstrated that combining bevacizumab with first-line chemotherapy significantly improves progression-free survival versus chemotherapy alone in HER2-negative locally recurrent/metastatic breast cancer (LR/mBC). However, data from Chinese populations are limited and possible di...

journal_title：Chinese medical journal

authors： Xu BH,Jiang ZF,Shen ZZ,Guan ZZ,Chen ZD,Cheng Y,Zheng H,Jiang J,Wang XJ,Tong ZS,Qin SK,Luo Y,Yao M,Wang LW,He J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q11 deletion syndrome (22q11DS). HIRA (histone cell cycle regulator) gene, as one of the candidate genes located at the critical region of 22q11DS, was reported as possibly relevant to CTD in animal models. This study aimed...

journal_title：Chinese medical journal

authors： Ju ZR,Wang HJ,Ma XJ,Ma D,Huang GY

更新日期：2016-10-20 00:00:00

abstract：BACKGROUND:Cerebral ischemia-reperfusion injury is the main reason for the loss of neurons in the ischemic cerebrovascular disease. Therefore, to deeply understand its pathogenesis and find a new target is the key issue to be solved. This research aimed to investigate the neuroprotective effects of salvianolic acid B (...

journal_title：Chinese medical journal

authors： Wang Y,Jiang YF,Huang QF,Ge GL,Cui W

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Myocardial protection during off-pump coronary artery bypass grafting (OPCABG) is a multifactorial problem in which maintaining stable systemic hemodynamics is very important. In this study passive graft perfusion (PGP) was applied to investigate the effect during and after OPCABG as evaluated by cardiac tro...

journal_title：Chinese medical journal

authors： Lu F,Ji BY,Liu JP,Liu MZ,Wang GY,Hu SS

更新日期：2007-02-05 00:00:00

abstract：BACKGROUND:Recently, conservative surgery is acceptable in young patients with borderline ovarian tumor and ovarian cancer. The preservation of these patients' future fertility has been the focus of recent interest. This study aimed to observe the effect of gonadotropin-releasing hormone agonists (GnRHa) cotreatment du...

journal_title：Chinese medical journal

authors： Zhu HL,Wang Y,Li XP,Wang CH,Wang Y,Cui H,Wang JL,Wei LH

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Intra-articular fractures of the fingers are common problems to emergency physicians and hand surgeons. Inappropriate management of these injuries may result in chronic pain, stiffness, deformity, or post traumatic arthritis. Ideal treatment necessitates the restoration of a stable and congruent joint that w...

journal_title：Chinese medical journal

authors： Li WJ,Tian W,Tian GL,Chen SL,Zhang CQ,Xue YH,Li ZZ,Zhu Y

更新日期：2009-11-05 00:00:00

abstract：BACKGROUND:Novel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A (H10N8) virus which can infect humans and cause severe diseases. METHODS:Collecting clinical data of three cases of human infection with a novel reas...

journal_title：Chinese medical journal

authors： Zhang W,Wan J,Qian K,Liu X,Xiao Z,Sun J,Zeng Z,Wang Q,Zhang J,Jiang G,Nie C,Jiang R,Ding C,Li R,Horby P,Gao Z

更新日期：2014-01-01 00:00:00

abstract：:After cis-diamminedichloroplatinum ethylcellulose microcapsules (CDDPmc) and unencapsulated CDDP were infused into the hepatic arteries of New Zealand rabbits, both CDDP concentrations in the circulating blood and in hepatic tissue were measured at different time intervals. In the rabbits infused with CDDPmc, the CDDP...

journal_title：Chinese medical journal

authors： Wang Y,Wu MC,Zhang XH

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:In 2008, infants in some areas of China suffered from stones of the urinary system which were caused by melamine-contaminated milk formula. Most of the infants were asymptomatic, and a few suffered from acute renal failure induced by urinary obstruction by stones. This study aimed to assess the significance ...

journal_title：Chinese medical journal

authors： Shen Y,Liu XR,Zhang GJ,Zhou N

更新日期：2009-02-05 00:00:00

abstract：Background:The effect of maternal weights on the risk of iron deficiency anemia (IDA) during pregnancy remains unclear. The study aimed to investigate the association between maternal weight indicators and IDA during pregnancy. Methods:We conducted a cohort study to examine the association between maternal weight indi...

journal_title：Chinese medical journal

authors： Tan J,Qi YN,He GL,Yang HM,Zhang GT,Zou K,Luo W,Sun X,Liu XH

更新日期：2018-11-05 00:00:00