Calcification of bilateral ureters: a novel association with systemic lupus erythematosus.

abstract：OBJECTIVE:To summarize the progress of surgical treatment of hepatocellular carcinoma (HCC) and related basic research at the Liver Cancer Institute of Shanghai Medical University in the recent years, with special reference to recurrence and metastasis. METHODS:Published and unpublished update clinical and experimenta...

journal_title：Chinese medical journal

authors： Tang Z,Zhou X,Lin Z,Yang B,Ma Z,Ye S,Wu Z,Fan J,Liu Y,Liu K,Qin L,Tian J,Sun H,He B,Xia J,Qiu S,Zhou J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel re...

journal_title：Chinese medical journal

authors： Tang XF,Zhang JH,Wang J,Han YL,Xu B,Qiao SB,Wu YJ,Chen J,Wu Y,Chen JL,Gao RL,Yang YJ,Yuan JQ

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To report the surgical techniques and results of an 8-year follow-up study of 42 patients with a modified orthotopic ileal neobladder restoring normal anatomical relationship. METHODS:Total cystoprostatectomy was performed extraperitoneally. A 45 - 50 cm segment of the ileal loop was isolated, detubularized,...

journal_title：Chinese medical journal

authors： Huang J,Xu K,Yao Y,Guo Z,Lin T,Jiang C

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Sunitinib has been proved an effective new option for treatment of metastatic renal cell carcinoma (mRCC). Analysis of clinical data of 22 patients, who were exposed to sunitinib for at least 1 year, was conducted to evaluate the long-term efficacy and safety of sunitinib for the treatment of mRCC. METHODS:...

journal_title：Chinese medical journal

authors： Zhang CJ,Zhao PJ,Li XS,Zhao J,Huang LH,Song Y,Gong K,Shen C,Yu W,Song G,Zhao Z,Zhang Z,Zhang Q,He ZS,Jin J,Zhou LQ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:It has been proved that sevoflurane postconditioning (SpostC) could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiological effects of SpostC. The objective of the study was to investigate the effects of SpostC on action poten...

journal_title：Chinese medical journal

authors： Gong JS,Yao YT,Fang NX,Huang J,Li LH

更新日期：2012-10-01 00:00:00

abstract：:Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational leve...

journal_title：Chinese medical journal

authors： Song JK,Yin SY,Li W,Li XD,Luo Y,Luo Y,Xing M,Li B,Kuai L

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:Whether antibody to myelin oligodendrocyte glycoprotein (MOG) can be a diagnostic marker for multiple sclerosis (MS) is still controversial. Recent studies suggested that serum specific anti-MOG epitope antibody might be an MS specific marker. However, these studies did not include neuromyelitis optica (NMO)...

journal_title：Chinese medical journal

authors： Xu Y,Zhang Y,Liu CY,Peng B,Wang JM,Zhang XJ,Li HF,Cui LY

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To study protective immunity afforded by murine immunization with DNA vaccine of Schistosoma japonicum (S. japonicum) as measured by reduction in worm burden and host antibody, cytokines. METHODS:DNA vaccine pCD-Sj32 was constructed, identified and expressed. pCD-Sj32 could induce substantial protective immu...

journal_title：Chinese medical journal

authors： Shi Y,Xie L,Li C,Han J

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The primary reasons for local recurrence and therapeutic failure in the treatment of malignant gliomas are the invasion and interactions of tumor cells with surrounding normal brain cells. However, these tumor cells are hard to be visualized directly in histopathological preparations, or in experimental glio...

journal_title：Chinese medical journal

authors： Dong J,Dai XL,Lu ZH,Fei XF,Chen H,Zhang QB,Zhao YD,Wang ZM,Wang AD,Lan Q,Huang Q

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To evaluate mice as experimental animals for Chlamydia pneumoniae (C. pneumoniae) infection and investigate the pathogenesis of C. pneumoniae derived pneumonitis. METHODS:Icr mice were inoculated with the C. pneumoniae strain, CWL-029, either intranasally or intravenously. After a single dose inoculation, mi...

journal_title：Chinese medical journal

authors： Shi Y,Yin J,Zhan H,Feng G,Zhang X,Su X,Song Y,Xia X,Zhou X,Shen P

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:A practical problem impeding clinical translation is the limited bone formation seen in artificial bone grafts. Low-pressure/vacuum seeding and dynamic culturing in bioreactors have led to a greater penetration into the scaffolds, enhanced production of bone marrow cells, and improved tissue-engineered bone ...

journal_title：Chinese medical journal

authors： Wang J,Wang J,Yoshinori A,Paul F,Shen H,Chen J,Sotome S,Liu Z,Shinomiya K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Nucleostemin is essential for the proliferation and survival of stem and cancer cells, but it is unknown whether this newly identified molecule is involved in prostate cancer pathogenesis. METHODS:Total RNA and protein were extracted from prostate cancer tissues and PC-3, LNCap and DU145 cell lines. The nuc...

journal_title：Chinese medical journal

authors： Liu RL,Zhang ZH,Zhao WM,Wang M,Qi SY,Li J,Zhang Y,Li SZ,Xu Y

更新日期：2008-02-20 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of misoprostol in term labour induction. DATA SOURCES:Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand sea...

journal_title：Chinese medical journal

authors： Li XM,Wan J,Xu CF,Zhang Y,Fang L,Shi ZJ,Li K

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Gastric stromal tumors arising from the muscularis propria are located in deeper layers. Endoscopic resection may be contraindicated due to the possibility of perforation. These tumors are therefore usually removed by surgical or laparoscopic procedures. This study evaluated the curative effects, safety and ...

journal_title：Chinese medical journal

authors： Wu CR,Huang LY,Guo J,Zhang B,Cui J,Sun CM,Jiang LX,Wang ZH,Ju AH

更新日期：2015-06-05 00:00:00

abstract：BACKGROUND:Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a newly identified mRNA-binding protein that is involved in embryogenesis and carcinogenesis of some malignant tumors. The aim of this study was to detect the expression of IMP3 protein in gastric adenocarcinoma (GAC) and the correlation with cli...

journal_title：Chinese medical journal

authors： Wang L,Li HG,Xia ZS,Lü J,Peng TS

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To investigate the role of a potential diabetes-related mitochondrial region, which includes two previously reported mutations, 3243A-->G and 3316G-->A, in Chinese patients with adult-onset type 2 diabetes. METHODS:A total of 277 patients and 241 normal subjects were recruited for the study. Mitochondrial nt...

journal_title：Chinese medical journal

authors： Yang T,Lam CW,Tsang MW,Tong SF,Kam GY,Chan LY,Poon PM,Wu X,Pang CP

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:The P53 tumor suppressor gene shows the most frequent genetic alteration in human tumors. Mutation, deletion and rearrangement of P53 gene have been found in several types of neoplasm including osteosarcoma. The present study is to clarify the status of abnormalities of this gene in osteosarcoma in China. MA...

journal_title：Chinese medical journal

authors： Guo W,Wang X,Feng C

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to review the current status of calcium phosphate (CaP) scaffolds combined with bone morphogenetic proteins (BMPs) or mesenchymal stem cells (MSCs) in the field of bone tissue engineering (BTE). DATE SOURCES:Data cited in this review were obtained primarily from PubMed and Medli...

journal_title：Chinese medical journal

authors： Sun H,Yang HL

更新日期：2015-04-20 00:00:00

abstract：BACKGROUND:miR-338-3p is a recently discovered miRNA and is involved in cell differentiation. However, few data are yet available on the aberrant expression of miR-338-3p in human colorectal carcinoma (CRC). This work aimed to investigate the relationship between miR-338-3p expression pattern and clinicopathological fe...

journal_title：Chinese medical journal

authors： Sun K,Su G,Deng H,Dong J,Lei S,Li G

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:It has been long suggested that abnormal clinical factors in the body, such as dyslipidemia and diabetes, can affect the presence of atherosclerosis. However, few studies on the effect of factors within the normal range, such as the loss of renal function with age, on the prevalence of atherosclerosis are fe...

journal_title：Chinese medical journal

authors： Jiang SM,Sun XF,Gu HX,Chen YS,Xi CS,Qiao X,Chen XM

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of cordocentesis for prenatal diagnosis of various fetal diseases. PATIENTS AND METHODS:Fetal blood sampling was performed in 30 pregnancies from gestational week 19 to 36 for various prenatal diagnoses. We used Aloka SSD-650 real-time ultrasound scanner with 3.5 mHz curvi...

journal_title：Chinese medical journal

authors： Xiang Y,Sun N,Chang X,Bian X,Wang F

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The rapid transmission and high mortality rate made severe acute respiratory syndrome (SARS) a global threat for which no efficacious therapy is available now. Without sufficient knowledge about the SARS coronavirus (SARS-CoV), it is impossible to define the candidate for the anti-SARS targets. The putative ...

journal_title：Chinese medical journal

authors： Lu JH,Zhang DM,Wang GL,Guo ZM,Zhang CH,Tan BY,Ouyang LP,Lin L,Liu YM,Chen WQ,Ling WH,Yu XB,Zhong NS

更新日期：2005-05-05 00:00:00

abstract：BACKGROUND:A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A (SAA) levels and the incidence of atherosclerosis (AS) in patients with short-duration type 2 diabetes mellitus (T2DM) without macroangiopathy, and whether intensive multif...

journal_title：Chinese medical journal

authors： Du JL,Liu JF,Men LL,Yao JJ,Sun LP,Sun GH,Song GR,Yang Y,Bai R,Xing Q,Li CC,Sun CK

更新日期：2009-11-05 00:00:00

abstract：OBJECTIVES:To analyze the FBN1 mutations in Chinese patients with Marfan syndrome (MFS) and to make a genetic diagnosis based on haplotype linkage analysis for MFS. METHODS:Nine MFS families (17 patients) were analyzed with single strand conformation polymorphism (SSCP) and sequencing. Four primers were designed for t...

journal_title：Chinese medical journal

authors： Wang B,Hu D,Xia J,Li Q,Yang J,Lu G

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The importance of polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene for the prediction of the response to fluorouracil-based adjuvant chemotherapy in gastric cancer patients remains unclear. The aim of this study is to assess the predictive value of several polymorphisms of the MTHFR gene...

journal_title：Chinese medical journal

authors： Zhang X,Bai Z,Chen B,Feng J,Yan F,Jiang Z,Zhong Y,Wu J,Cheng L,Lu Z,Tong N,Zhang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Hirayama disease is a rare disease characterized by juvenile-onset of asymmetric amyotrophy, of which etiology has not been clarified. The aim of our study was to investigate the clinical and neurophysiologic characteristics of Hirayama disease. METHODS:Neurophysiological tests, including nerve conduction s...

journal_title：Chinese medical journal

authors： Wang XN,Cui LY,Liu MS,Guan YZ,Li BH,DU H

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The incidence of no reflow phenomenon limits the clinical outcomes of percutaneous coronary intervention (PCI). This randomized controlled study was designed to evaluate the immediate protective effects of intensive statin pretreatment on myocardial perfusion and myocardial ischemic injury during PCI. METHO...

journal_title：Chinese medical journal

authors： Jia XW,Fu XH,Zhang J,Gu XS,Fan WZ,Wu WL,Hao GZ,Li SQ,Jiang YF

更新日期：2009-03-20 00:00:00

abstract：BACKGROUND:Human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) could be induced to differentiate into insulin producing cells (IPCs) in vitro, which have good application potential in the cell replacement treatment of type-1 diabetes. However, the mechanisms regulating this differentiation have remaine...

journal_title：Chinese medical journal

authors： Hu YH,Wu DQ,Gao F,Li GD,Zhang XC

更新日期：2010-03-05 00:00:00

abstract：OBJECTIVE:To investigate the protective effect of dl-3-n-butylphthalide (NBP) as an anti-cerebral ischemic drug on brain damage 24 h after closed head injury in mice. METHODS:Closed head injury was induced by dropping a 50-g weight from a height of 18 cm on a metal impounder resting on the parietal bone in mice. RESU...

journal_title：Chinese medical journal

authors： Chong Z,Feng Y

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To study the interaction between oncogene mdm2 and wp53 in human glandular lung cancer cell line GLC-82. METHODS:By lipofectamine-mediated DNA transfection, wp53 and mdm2 were transfected separately or co-transfected into GLC-82 cells via retrovival vector pDOR-neo, a carrier of wp53 and mdm2. RESULTS:The g...

journal_title：Chinese medical journal

authors： Li P,Rao G,Chen Y,Ding Z,Yu W

更新日期：1999-09-01 00:00:00