Cordocentesis: a useful method for prenatal diagnosis.

abstract：OBJECTIVE:In order to explore the possible roles played by the autoimmune mechanism in the progression of myocarditis into dilated cardiomyopathy (DCM) using an animal model, we investigated whether autoimmune myocarditis might develop into DCM. METHODS:Experimental Balb/C mice (n = 20) were immunized with cardiac myo...

journal_title：Chinese medical journal

authors： Wang Z,Liao Y,Dong J,Li S,Wang J,Fu ML

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Diffusion tensor imaging (DTI) permits quantitative examination within the pyramidal tract (PT) by measuring fractional anisotropy (FA). To the best of our knowledge, the inter-variability measures of FA along the PT remain unexplained. A clear understanding of these reference values would help radiologists ...

journal_title：Chinese medical journal

authors： Roldan-Valadez E,Rios-Piedra E,Favila R,Alcauter S,Rios C

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To explore the immune promotion mechanism of retinoic acid (RA). METHODS:Reverse Transcription-Polymerase chain reaction (RT-PCR) was used to detect the gene expression of insulin like growth factor I (IGF-I) and IGF receptors (IGF-IR and IGF-IIR) in vitro, and their regulation by RA in human cord blood lymp...

journal_title：Chinese medical journal

authors： Yang Y,Wang W,Su Y

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To elucidate the transmission dynamic and epidemic trend of bancroftian filariasis occurred under the condition with no control measure taken 5 years after elimination of filariasis. METHODS:A 10-year longitudinal observation (from 1984 to 1994) was made in Huayuan Village in Shengli Township of Tancheng Cou...

journal_title：Chinese medical journal

authors： Wang P,Wang F,Sun Y,Wang J,Kou J,Huang Y,Kang X,Wan G,Liang Y,Wang Q

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Coronary atherosclerotic plaque could go through rapid progression and induce adverse cardiac events. This study aimed to evaluate the impacts of smoking status on clinical outcomes of coronary non-target lesions. METHODS:Consecutive patients with coronary heart disease who underwent two serial coronary ang...

journal_title：Chinese medical journal

authors： Xu HB,Wang J,Chen JL,Guo C,Yuan JS,Duan X,Hu FH,Yang WX,Luo XL,Liu R,Cui JG,Liu SW,Gao XJ,Chun YS,Qiao SB

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:Congenital uterine anomalies are associated with the highest incidence of reproductive failure and obstetric complications. This study aimed to summarize the clinical characteristics and prenatal outcome of pregnancy in women with congenital uterine malformations. METHODS:This retrospective study evaluated ...

journal_title：Chinese medical journal

authors： Zhang Y,Zhao YY,Qiao J

更新日期：2010-02-20 00:00:00

abstract：BACKGROUND:It remains controversial whether patients with Stage II colorectal cancer would benefit from adjuvant chemotherapy after radical resection. The aim of this study was to establish two mathematical models to identify the suitable patients for adjuvant chemotherapy. METHODS:The current study comprised of two s...

journal_title：Chinese medical journal

authors： Wei B,Zheng XM,Lei PR,Huang Y,Zheng ZH,Chen TF,Huang JL,Fang JF,Liang CH,Wei HB

更新日期：2017-09-05 00:00:00

abstract：Objective:Acute respiratory distress syndrome (ARDS) is an acute and lethal clinical syndrome that is characterized by the injury of alveolar epithelium, which impairs active fluid transport in the lung, and impedes the reabsorption of edema fluid from the alveolar space. This review aimed to discuss the role of pro-re...

journal_title：Chinese medical journal

authors： Wang Q,Yan SF,Hao Y,Jin SW

更新日期：2018-04-20 00:00:00

abstract：:This study demonstrates that there are distinct abnormalities of vitamin D and calcium metabolism in children with nephrotic syndrome (NS) and normal renal function. In patients with active NS, serum calcium, ionized calcium, 25-OHD3 and CT were decreased, plasma PTH level was increased and serum ALP was elevated. The...

journal_title：Chinese medical journal

authors： Huang JP,Bai KM,Wang BL

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Paraquat (PQ; 1, 1'-dimethyl-4, 4'-bipyridinium), a widely used herbicide that is structurally similar to the known dopaminergic neurotoxicant MPTP (1-methyl-1, 2, 3, 6-tetrahydropyridine), has been suggested as a potential etiologic factor for the development of Parkinson's disease (PD). Aging is an accepte...

journal_title：Chinese medical journal

authors： Li X,Yin J,Cheng CM,Sun JL,Li Z,Wu YL

更新日期：2005-08-20 00:00:00

abstract：OBJECTIVE:To study the expression of vascular endothelial growth factor (VEGF) in different parts of heart during early acute myocardial ischemia. METHODS:The expression of VEGF in control and study group in rats was performed with the Strept Avidin-Biotin-Peroxidase Complex (SABC) method. RESULTS:A rapid expression ...

journal_title：Chinese medical journal

authors： Chen J,Xu X,Wu X,Zhu J

更新日期：1999-08-01 00:00:00

abstract：:The unclear DNA content was measured with flow cytometry (FCM) in 167 specimens of normal nasopharyngeal epithelium (NE), adjacent tissue to carcinoma (ATC) and nasopharyngeal carcinoma (NPC). All 20 patients with NE showed diploid, whereas 38 (38%) of 101 patients with NPC, 7 (58%) of 12 patients with recurrent NPC, ...

journal_title：Chinese medical journal

authors： Zhao SP,Tao ZD,Xiao JY,Xiao PT,Peng YY

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Overexpression of breast cancer-specific gene 1 (SNCG) is associated with poor prognosis in advanced breast cancer patients. This study aimed to determine the effects of SNCG knockdown in breast cancer cells by using small hairpin RNA (shRNA). METHODS:Four different SNCG shRNA oligonucleotides were designed...

journal_title：Chinese medical journal

authors： Shen PH,Fan QX,Li YW,Zhang W,He XK,Wang Z,Zhang YH

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The present study was aimed to investigate the usage of aspirin for the secondary prevention of ischemic stroke, evaluate the correlated factors, and analyze the reasons for not taking and irregularly taking aspirin. METHODS:The patients in this group were all stroke survivors who have formerly been diagnos...

journal_title：Chinese medical journal

authors： Ke XJ,Yu YF,Guo ZL,Xu K,Hai H,Zhang AH,Jiang H,Peng H

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:P53 is one of the most studied tumor suppressors in the cancer research, and over 50% of human tumors carry P53 mutations. MDM-2 is amplified and/or overexpressed in a variety of human tumors of diverse tissue origin. The aim of this study was to examine the expression of P53 protein and MDM-2 protein in gli...

journal_title：Chinese medical journal

authors： Wang AL,Liu ZX,Li G,Zhang LW

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:To study the interrelation between nitric oxide (NO) and endothelin-1 (ET1) in experimental acute hypoxic rats, and to evaluate the mechanism of acute hypoxic pulmonary hypertension affected by NO and ET1 and its intervention. METHODS:Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemi...

journal_title：Chinese medical journal

authors： Wang Y,Zhang L,Shen W,Chen L,Fan S

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Bone grafting is commonly used to repair bone defects. As the porosity of the graft scaffold increases, bone formation increases, but the strength decreases. Early attempts to engineer materials were not able to resolve this problem. In recent years, nanomaterials have demonstrated the unique ability to impr...

journal_title：Chinese medical journal

authors： Tang D,Xu G,Yang Z,Holz J,Ye X,Cai S,Yuan W,Wang Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Cubital tunnel syndrome is a well-recognized clinical condition and is the second most common peripheral compression neuropathy. This study was designed to investigate the causes of cubital tunnel syndrome by surgical means and to assess the clinical value of the neurophysiological diagnosis of cubital tunne...

journal_title：Chinese medical journal

authors： Jia ZR,Shi X,Sun XR

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcriptional factor that could improve the stimulation of angiogenesis and the metabolic adaptation of tumor cells to hypoxia. A recent study showed that HIF-1alpha could induce colon cancer cells epithelial-mesenchymal transition (EMT). However, no eviden...

journal_title：Chinese medical journal

authors： Luo Y,He DL,Ning L,Shen SL,Li L,Li X

更新日期：2006-05-05 00:00:00

abstract：BACKGROUND:Myocardial bridging with systolic compression of the left anterior descending coronary artery (LAD) may be associated with myocardial ischaemia. The clinical outcome in patients with surgical treatment for symptomatic myocardial bridging remains undetermined. This study assessed the middle- and long-term res...

journal_title：Chinese medical journal

authors： Huang XH,Wang SY,Xu JP,Song YH,Sun HS,Tang Y,Dong C,Yang YJ,Hu SS

更新日期：2007-09-20 00:00:00

abstract：BACKGROUND:Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly, and SVA with discrete membranous subaortic stenosis is even rarer. The aim of the study was to make sure the incidence of SVA with discrete membraneous subaortic stenosis in SVA and their surgical results. We retrospectively analyzed 234 patients re...

journal_title：Chinese medical journal

authors： Guo HW,Chang Q,Yu CT,Sun XG,Qian XY,Hu SS

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To explore the management of cerebral ischemia caused by Takayasu's arteritis. METHODS:Ninety-three cases treated from June 1984 to September 1999 at the General Post & Telecom Hospital, the Sir Run Run Shaw Hospital, the First Affiliated Hospital of Zhejiang University, the Second Medical College of Beijing...

journal_title：Chinese medical journal

authors： Wang Z,Shen L,Yu J,Gu Y,Wang S,Guan H,Wu Q,Zhang X,Li M,Wu J,Li G,Pan S,Zhang H,Jin W

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To determine the effects and toxicity of interstitial brachytherapy using iridium-192 on brain malignant gliomas. METHODS:Between January 1992 and January 1995, 56 patients with anaplastic astrocytoma and glioblastoma multiforme were treated with stereotactic brachytherapy using temporary high-activity iridi...

journal_title：Chinese medical journal

authors： Liu Z,Yu X,Guo Y,Li S,Cui Y,Yu X,Yuan Z,Kang J

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term efficacy and safety of lamivudine therapy for the treatment of chronic hepatitis B and the clinical influence of emergence of tyrosine methionine aspartic acid (YMDD) motif mutation of hepatitis B virus (HBV). METHODS:This multicenter, double-blind, randomized, placebo controlled tr...

journal_title：Chinese medical journal

authors： Yao G,Cui Z,Wang B,Yao J,Zeng M

更新日期：2002-12-01 00:00:00

abstract：Background:Technical aspects of the correct placement of medial support locking screws in the locking plate for proximal humerus fractures remain incompletely understood. This study was to evaluate the clinical relationship between the number of medial support screws and the maintenance of fracture reduction after lock...

journal_title：Chinese medical journal

authors： Zeng LQ,Zeng LL,Jiang YW,Wei HF,Zhang W,Chen YF

更新日期：2018-08-05 00:00:00

abstract：BACKGROUND:Three randomised trials have demonstrated that combining bevacizumab with first-line chemotherapy significantly improves progression-free survival versus chemotherapy alone in HER2-negative locally recurrent/metastatic breast cancer (LR/mBC). However, data from Chinese populations are limited and possible di...

journal_title：Chinese medical journal

authors： Xu BH,Jiang ZF,Shen ZZ,Guan ZZ,Chen ZD,Cheng Y,Zheng H,Jiang J,Wang XJ,Tong ZS,Qin SK,Luo Y,Yao M,Wang LW,He J

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of Burn Healing Liquid (BHL) on the proliferation of keratinocytes and fibroblasts and to explore the potential effect of BHL on fibroblast contraction. METHODS:Human keratinocytes and dermal fibroblasts were cultured in media containing serial dilutions of BHL followed by cell pro...

journal_title：Chinese medical journal

authors： Su Y,Chen B,Thang PT,Hughes MA,Xu X,Cherry GW

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Inner retinal oxygenation response (ΔPO(2)) is a worldwide study focus. However, the relevant reports on its radiological measurements are limited. In this study, magnetic resonance imaging (MRI), employing T1 weighted image (T1WI), was used to detect changes in ΔPO(2) following 100% oxygen inhalation in hum...

journal_title：Chinese medical journal

authors： Xu QG,Chen QH,Xian JF,Wang ZC

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Aerosolized amikacin (AA) is a current option for the management of ventilator-associated pneumonia (VAP) caused by multidrug-resistant Gram-negative bacteria (MDR-GNB), as it is reported that AA could increase the alveolar level of the drug without increasing systemic toxicity. This study aimed to evaluate ...

journal_title：Chinese medical journal

authors： Liu C,Zhang YT,Peng ZY,Zhou Q,Hu B,Zhou H,Li JG

更新日期：2017-05-20 00:00:00

abstract：OBJECTIVE:To explore the pathogenesis of glucose metabolic disorder and insulin resistance in critically ill children under severe stress. METHODS:To test glucose, lactate, glucagon, insulin, c-peptide, cortisol levels in 50 critically ill children. While we measured 125I-insulin binding to erythrocytes of 13 critical...

journal_title：Chinese medical journal

authors： Xu F,Yang X,Lu Z,Kuang F

更新日期：1996-10-01 00:00:00